Michael Freeley

发表

Microdamage: a cell transducing mechanism based on ruptured osteocyte processes.

David Taylor, J. Hazenberg, Michael Freeley, 2006, Journal of biomechanics.

Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.

Jongsun Park, R. Wange, Y. Volkov, 2007, Cellular signalling.

Differential modulation of Helicobacter pylori lipopolysaccharide‐mediated TLR2 signaling by individual Pellino proteins

D. Kelleher, P. Moynagh, Michael Freeley, 2017, Helicobacter.

LFA-1/ICAM-1 Ligation in Human T Cells Promotes Th1 Polarization through a GSK3β Signaling–Dependent Notch Pathway

B. Boehm, A. Kizhakeyil, N. Verma, 2016, The Journal of Immunology.

Deoxycholic acid induces proinflammatory cytokine production by model oesophageal cells via lipid rafts

A. Long, J. Gilmer, Michael Freeley, 2021, The Journal of Steroid Biochemistry and Molecular Biology.

RNAi Screening with Self-Delivering, Synthetic siRNAs for Identification of Genes That Regulate Primary Human T Cell Migration

D. Leake, A. Davies, D. Kelleher, 2015, Journal of biomolecular screening.

RAB40C regulates RACK1 stability via the ubiquitin–proteasome system

G. Baillie, P. Kiely, A. Long, 2018, Future science OA.

RAB 40 C regulates RACK 1 stability via the ubiquitin – proteasome system

G. Baillie, P. Kiely, A. Long, 2018 .

The two hit hypothesis: an improved method for siRNA-mediated gene silencing in stimulated primary human T cells.

A. Long, Michael Freeley, 2013, Journal of immunological methods.

The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration.

Y. Volkov, D. Kelleher, A. Long, 2006, Gastroenterology.

CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes.

A. Fanning, Y. Volkov, D. Kelleher, 2005, International immunology.

Regulating the Regulator: Phosphorylation of PKC θ in T Cells

A. Long, Michael Freeley, 2012, Front. Immun..

Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes.

Y. Volkov, D. Kelleher, A. Long, 2005, Biochemical and biophysical research communications.

Protein kinase C delta is a substrate of tissue transglutaminase and a novel autoantigen in coeliac disease.

C. Feighery, A. Long, Michael Freeley, 2013, Clinical immunology.

Current postgraduate training programs and online courses in precision medicine

Michael Freeley, 2019, Expert review of molecular diagnostics.

Advances in siRNA delivery to T-cells: potential clinical applications for inflammatory disease, cancer and infection.

A. Long, Michael Freeley, 2013, The Biochemical journal.

Candidate Gene Knockdown in Celiac Disease.

R. McManus, A. Long, Michael Freeley, 2015, Methods in molecular biology.

Analysis of dynamic tyrosine phosphoproteome in LFA‐1 triggered migrating t‐cells

C. Botting, N. Verma, Y. Volkov, 2011, Journal of cellular physiology.

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

J. Conroy, J. McKeating, D. Doherty, 2011, Hepatology.

L-plastin Expression in HCT 116 Colorectal Cells Increases Migration and ROS in an NADPH Oxidase-Dependent Manner

A. Long, Michael Freeley, E. Foran, 2022 .

Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression

O. Sheils, S. Aherne, Michael Freeley, 2016, International journal of molecular medicine.

Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites.

D. Kelleher, A. Long, Michael Freeley, 2011, Cellular signalling.

L-Plastin Regulates Polarization and Migration in Chemokine-Stimulated Human T Lymphocytes

D. Kashanin, A. Davies, D. Kelleher, 2012, The Journal of Immunology.

CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

D. Doherty, A. Long, T. Rogers, 2018, Front. Immunol..

Phosphorylation of Rab5a Protein by Protein Kinase Cϵ Is Crucial for T-cell Migration*

G. Baier, F. Fresser, N. Verma, 2014, The Journal of Biological Chemistry.

Protein kinase C: a regulator of cytoskeleton remodelling and T-cell migration.

A. Long, Michael Freeley, 2014, Biochemical Society transactions.

A High-Content Analysis Toolbox Permits Dissection of Diverse Signaling Pathways for T Lymphocyte Polarization

A. Davies, D. Kelleher, D. Dunican, 2010, Journal of biomolecular screening.

Phosphorylation of Rab5a Protein by Protein Kinase Cϵ Is Crucial for T-cell Migration*

G. Baier, F. Fresser, N. Verma, 2014, The Journal of Biological Chemistry.

Comment on "PDK1 Nucleates T Cell Receptor-Induced Signaling Complex for NF-κB Activation"

G. Baier, A. Long, S. Shaw, 2006, Science.

Analysis of dynamic tyrosine phosphoproteome in LFA‐1 triggered migrating t‐cells

C. Botting, N. Verma, Y. Volkov, 2011, Journal of cellular physiology.

Bile acids induce IL-1α and drive NLRP3 inflammasome-independent production of IL-1β in murine dendritic cells

E. Lavelle, Michael Freeley, E. Oleszycka, 2023, Frontiers in immunology.