B. Kream

发表

Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties.

R. Rizzoli, C. Rosen, P. Ammann, 2011, Bone.

Identification of Novel cAMP Responsive Element Modulator (CREM) Isoforms Expressed by Osteoblasts

Y-F Huang, B. Kream, F. Liu, 2005, Calcified Tissue International.

Parathyroid Hormone Induces Expression of the Inducible cAMP Early Repressor in Osteoblastic MC3T3‐E1 Cells and Mouse Calvariae

S. Tetradis, J. Nervina, B. Kream, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Insulin increases the steady state level of alpha-1(I) procollagen mRNA in the osteoblast-rich segment of fetal rat calvaria.

D. Rowe, R. Craig, B. Kream, 1989, Endocrinology.

Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling

Stephen N. Jones, C. Lengner, G. Stein, 2006, The Journal of cell biology.

Basic fibroblast growth factor inhibits type I collagen gene expression in osteoblastic MC3T3-E1 cells.

M. Hurley, B. Kream, L. Raisz, 1993, The Journal of biological chemistry.

Regulation of bone formation.

B. Kream, L. Raisz, 1983, The New England journal of medicine.

Regulation of bone formation (second of two parts).

B. Kream, L. Raisz, Raisz Lg, 1983, The New England journal of medicine.

Identification of Residues Essential for HSV ICP8 Mediated Annealing of ssDNA

S. Weller, B. Kream, Jaliyah Peterson, 2020 .

The P2 Promoter of the CREM Gene is Responsive to cAMP-PKA Signaling Pathway in Osteoblastic MC3T3-E1 Cells

B. Kream, Yu-feng Huang, 2011 .

The Role of Proximal cAMP Responsive Element (CRE) in Parathyroid Hormone and cAMP Induction of Human Interleukin-6 Promoter Activity

B. Kream, J. Harrison, Yu-feng Huang, 2010 .

Expression of inducible cAMP early repressor is coupled to the cAMP-protein kinase A signaling pathway in osteoblasts.

C. Molina, S. Tetradis, J. Nervina, 2003, Bone.

Regulation of COL1A1 expression in type I collagen producing tissues: Identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice

D. Rowe, R. Salvatori, B. Kream, 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Transgenic mice with osteoblast-targeted insulin-like growth factor-I show increased bone remodeling.

C. Rosen, G. Gronowicz, B. Kream, 2006, Bone.

The role of bone morphogenetic protein 4 (BMP-4) in tooth development

Jian Q. Feng, S. Harris, S. E. Harris, 2008 .

The role and mechanisms of bone morphogenetic protein 4 and 2 (BMP-4 and BMP-2) in postnatal skeletal development

B. Hogan, Y. Mishina, Jian Q. Feng, 2008 .

Genetic approaches to determine the role of glucocorticoid signaling in osteoblasts

H. Woitge, B. Kream, J. Harrison, 2002, Endocrine.

Rearrangement of a conditional allele regardless of inheritance of a Cre recombinase transgene

B. Kream, R. Cochrane, S. Clark, 2007, Genesis.

Calvariae from Fetal Mice with a Disrupted Igf1 Gene Have Reduced Rates of Collagen Synthesis but Maintain Responsiveness to Glucocorticoids

H. Woitge, B. Kream, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Impact of Targeted PPARγ Disruption on Bone Remodeling

Nianlan Yang, M. Hamrick, C. Isales, 2015, Molecular and Cellular Endocrinology.

Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice.

Q. Gao, C. Hao, M. Breyer, 2009, Bone.

CREM deficiency in mice alters the response of bone to intermittent parathyroid hormone treatment.

G. Gronowicz, Fei-peng Liu, B. Kream, 2007, Bone.

Transgenic expression of 11beta-hydroxysteroid dehydrogenase type 2 in osteoblasts reveals an anabolic role for endogenous glucocorticoids in bone.

L. B. Sher, H. Woitge, G. Gronowicz, 2004, Endocrinology.

Characterization of the effect of insulin on collagen synthesis in fetal rat bone.

E. Canalis, B. Kream, L. Raisz, 1985, Endocrinology.

Hormonal control of skeletal growth.

B. Kream, L. Raisz, 1981, Annual review of physiology.

Hormonal regulation of bone formation.

E. Canalis, B. Kream, L. Raisz, 1978, Recent progress in hormone research.

Impaired Cortical Bone Acquisition and Osteoblast Differentiation in Mice with Osteoblast-Targeted Disruption of Glucocorticoid Signaling

L. B. Sher, B. Kream, D. Adams, 2006, Calcified Tissue International.

Chapter 41 – Clinical and Basic Aspects of Glucocorticoid Action in Bone

B. Kream, 2002 .

Cloning and in Vitro Characterization ofα 1(I)-Collagen 11β-Hydroxysteroid Dehydrogenase Type 2 Transgenes as Models for Osteoblast-Selective Inactivation of Natural Glucocorticoids.

H. Woitge, Z. Krozowski, B. Kream, 2001, Endocrinology.

Cortisol enhances the anabolic effects of insulin-like growth factor I on collagen synthesis and procollagen messenger ribonucleic acid levels in cultured 21-day fetal rat calvariae.

B. Kream, L. Raisz, D. Petersen, 1990, Endocrinology.

The role of DNA synthesis in the responses of fetal rat calvariae to cortisol

B. Kream, L. Raisz, B. Lukert, 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Hormonal regulation of collagen synthesis in a clonal rat osteosarcoma cell line.

D. Rowe, R. Majeska, B. Kream, 1986, Endocrinology.

A specific high-affinity binding macromolecule for 1,25-dihydroxyvitamin D3 in fetal bone.

H. DeLuca, S. Yamada, B. Kream, 1977, Science.

A specific binding protein for 1,25-dihydroxyvitamin D3 in rat intestinal cytosol.

H. DeLuca, B. Kream, 1977, Biochemical and biophysical research communications.

The chick intestinal cytosol binding protein for 1,25-dihydroxyvitamin D3: a study of analog binding.

H. DeLuca, B. Kream, M. Jose, 1977, Archives of biochemistry and biophysics.

Specific cytosol-binding protein for 1,25-dihydroxyvitamin D3 in rat intestine.

H. DeLuca, S. Yamada, B. Kream, 1977, The Journal of biological chemistry.

Isolation of an inhibitor of 25-hydroxyvitamin D3-1-hydroxylase from rat serum.

H. DeLuca, B. Kream, K. Botham, 1976, Biochemistry.

Effects of transforming growth factor α and interleukin‐1 on DNA synthesis, collagen synthesis, procollagen mRNA levels, and prostaglandin E2 production in cultured fetal rat calvaria

M. Hurley, B. Kream, L. Raisz, 1989, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid Hormone Regulates the Expression of Fibroblast Growth Factor‐2 mRNA and Fibroblast Growth Factor Receptor mRNA in Osteoblastic Cells

M. Sabbieti, M. Hurley, S. Tetradis, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Failure of conventional doses of 1 alpha, 25-dihydroxycholecalciferol to correct hypocalcemia in a girl with idiopathic hypoparathyroidism.

H. DeLuca, J. Eisman, R. Chesney, 1977, The New England journal of medicine.

Origin of 25-hydroxyvitamin D3 binding protein from tissue cytosol preparations.

H. DeLuca, N. Kendrick, B. Kream, 1979, Archives of biochemistry and biophysics.

Rat plasma 25-hydroxyvitamin D3 binding protein: an inhibitor of the 25-hydroxyvitamin D3-1alpha-hydroxylase.

H. DeLuca, B. Kream, K. Botham, 1978, Archives of biochemistry and biophysics.

Vitamin D Regulation of Type I Collagen Expression in Bone

B. Kream, A. Lichtler, 2011 .

Activation of serum complement inhibits collagen synthesis in fetal rat bone in organ culture

A. Sandberg, B. Kream, L. Raisz, 1982, Calcified Tissue International.

Comparison of the effects of vitamin D metabolites on collagen synthesis and resportion of fetal rat bone in organ culture

B. Kream, L. Raisz, H. Simmons, 2006, Calcified Tissue International.

Hormonal regulation of collagen gene expression in osteoblastic cell-overview and new findings.

D. Rowe, B. Kream, A. Lichtler, 1989, Connective tissue research.

Interleukin‐1 Represses COLIA1 Promoter Activity in Calvarial Bones of Transgenic ColCAT Mice In Vitro and In Vivo

D. Rowe, P. Krebsbach, B. Kream, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells.

H. Herschman, S. Tetradis, B. Kream, 1997, Endocrinology.

Prostaglandin E2 inhibits alpha 1(I)procollagen gene transcription and promoter activity in the immortalized rat osteoblastic clonal cell line Py1a.

B. Kream, L. Raisz, A. Lichtler, 1993, Molecular endocrinology.

GSK-3β function in bone regulates skeletal development, whole-body metabolism, and male life span.

J. Woodgett, G. Bell, G. Karsenty, 2013, Endocrinology.

Interleukin-1 alpha and phorbol ester inhibit collagen synthesis in osteoblastic MC3T3-E1 cells by a transcriptional mechanism.

B. Kream, D. Petersen, J. Lorenzo, 1990, Molecular endocrinology.

Regulation of the alpha 1(I) collagen promoter in vascular smooth muscle cells. Comparison with other alpha 1(I) collagen-producing cells in transgenic animals and cultured cells.

B. Sokolov, D. Breault, B. Kream, 1994, The Journal of biological chemistry.

Regulation of collagen synthesis in fetal rat calvaria by 1,25-dihydroxyvitamin D3.

D. Rowe, B. Kream, 1982, The Journal of biological chemistry.

Insulin-Like Growth Factor I Does Not Drive New Bone Formation in Experimental Arthritis

D. Baeten, B. Kream, R. Lories, 2016, PloS one.

Parathyroid hormone induces interleukin-6 heterogeneous nuclear and messenger RNA expression in murine calvarial organ cultures.

B. Kream, J. Lorenzo, J. Harrison, 1998, Bone.

Parathyroid hormone represses alpha 1(I) collagen promoter activity in cultured calvariae from neonatal transgenic mice.

D. Rowe, B. Kream, A. Lichtler, 1993, Molecular endocrinology.

Parathyroid hormone blocks the stimulatory effect of insulin-like growth factor-I on collagen synthesis in cultured 21-day fetal rat calvariae.

B. Kream, L. Raisz, D. Petersen, 1990, Bone.

Cortisol decreases bone formation by inhibiting periosteal cell proliferation.

B. Kream, L. Raisz, Y. S. Chyun, 1984, Endocrinology.

Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells

D. Rowe, P. Krebsbach, B. Kream, 1993, Molecular and cellular biology.

Differential utilization of regulatory domains within the alpha 1(I) collagen promoter in osseous and fibroblastic cells

D. Rowe, G. Gronowicz, D. Pavlin, 1992, The Journal of cell biology.

Transgenic Expression of COLlAl-Chloramphenicol Acetyltransferase Fusion Genes in Bone: Differential Utilization of Promoter Elements In Vivo and in Cultured Cells

D. Rowe, B. Kream, Charles, 2022 .

A sensitive, precise, and convenient method for determination of 1,25-dihydroxyvitamin D in human plasma.

H. DeLuca, J. Eisman, B. Kream, 1976, Archives of biochemistry and biophysics.

1,25-Dihydroxyvitamin D3 inhibition of col1a1 promoter expression in calvariae from neonatal transgenic mice.

D. Rowe, D. Pavlin, R. Salvatori, 1998, Biochimica et biophysica acta.

Parathyroid Hormone Induction of Cyclooxygenase-2 in Murine Osteoblasts: Role of the Calcium-Calcineurin-NFAT Pathway

H. Drissi, H. Herschman, B. Kream, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid hormone inhibits collagen synthesis and the activity of rat Col1a1 transgenes mainly by a cAMP‐mediated pathway in mouse calvariae

B. Kream, A. Lichtler, S. Clark, 2000, Journal of cellular biochemistry.

1,25-Dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8.

D. Rowe, B. Kream, A. Lichtler, 1989, Endocrinology.

Inhibition of bone collagen synthesis by the tumor promoter phorbol 12‐myristate 13‐acetate

J. Feyen, B. Kream, D. Petersen, 1988, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation.

P. Dechow, S. E. Harris, M. Harris, 2010, Bone.

Prostaglandin synthesis by fetal rat bone in vitro: evidence for a role of prostacyclin.

B. Kream, L. Raisz, K. C. Nicolaou, 1979, Prostaglandins.

Modulation of the Effects of Glucocorticoids on Collagen Synthesis in Fetal Rat Calvariae by Insulin‐like Growth Factor Binding Protein‐2

J. Feyen, S. Tetradis, B. Kream, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Structural determinants of the capacity of heparin to inhibit collagen synthesis in 21‐day fetal rat calvariae

M. Hurley, B. Kream, L. Raisz, 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid hormone alters collagen synthesis and procollagen mRNA levels in fetal rat calvaria.

D. Rowe, B. Kream, L. Raisz, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Clinical and Basic Aspects of Glucocorticoid Action in Bone

B. Kream, B. Lukert, L. Graves, 2008 .

Construction of DNA sequences complementary to rat alpha 1 and alpha 2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D.

D. Rowe, B. Kream, C. Genovese, 1984, Biochemistry.

Tissue-specific and dexamethasone-inducible expression of alkaline phosphatase from alternative promoters of the rat bone/liver/kidney/placenta gene.

B. Kream, J. Zernik, K. Twarog, 1991, Biochemical and biophysical research communications.

Variable effects of dexamethasone on protein synthesis in clonal rat osteosarcoma cells.

B. Kream, B. Hodge, 1988, Endocrinology.

New bone resorption stimulation factor elaborated by a human osteosarcoma cell line.

M. Viola, B. Kream, G. Eilon, 1984, Cancer research.

Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells

J. Nyman, Y. Mishina, D. Rowe, 2013, Journal of Cell Science.

Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation.

E. Canalis, B. Kream, Maobin Yang, 2010, Bone.

Transgenic Models of Bone Disease

B. Kream, J. Harrison, 2006 .

CHAPTER 27 – Transgenic Models of Bone Disease

B. Kream, J. Harrison, 2006 .

Osteoblast Deletion of Exon 3 of the Androgen Receptor Gene Results in Trabecular Bone Loss in Adult Male Mice

M. Bouxsein, David Handelsman, V. Glatt, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

D. Surdez, O. Delattre, A. Üren, 2016, Oncotarget.

Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.

G. Stein, J. Lian, J. Colby, 2010, Developmental biology.

Dexamethasone suppresses in vivo levels of bone collagen synthesis in neonatal mice.

B. Kream, L. Raisz, L G Raisz, 1997, Bone.

Pregnenolone-binding proteins in the rat adrenal cortex.

L. Sauer, B. Kream, 1977, Endocrinology.

Epidermal Growth Factor Receptor Plays an Anabolic Role in Bone Metabolism In Vivo

D. Threadgill, Yibin Kang, Xianrong Zhang, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Regulation of type I collagen gene expression in bone.

D. Rowe, P. Krebsbach, D. Pavlin, 1995, Connective tissue research.

CHAPTER 40 – Vitamin D Regulation of Type I Collagen Expression in Bone

B. Kream, 2005 .

In situ hybridization analysis of the expression of the type II collagen gene in the developing chicken limb bud.

B. Kream, H. Nah, W. Kulyk, 1988, Collagen and related research.

Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac.

P. Epstein, S. Ben-Sasson, B. Kream, 2013, The Biochemical journal.

Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues.

H. Woitge, Fei-peng Liu, B. Kream, 2004, The International journal of developmental biology.

Calcitonin induces expression of the inducible cAMP early repressor in osteoclasts

B. Kream, Maobin Yang, 2008, Endocrine.

Postnatal growth and bone mass in mice with IGF-I haploinsufficiency.

C. Rosen, B. Kream, D. Adams, 2006, Bone.

PDE8 Regulates Rapid Teff Cell Adhesion and Proliferation Independent of ICER

P. Epstein, S. Ben-Sasson, B. Kream, 2010, PloS one.

Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop

Sundeep Khosla, D. Kiel, M. Drezner, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

1,25-Dihydroxyvitamin D in biological fluids: a simplified and sensitive assay.

H. DeLuca, J. Eisman, B. Kream, 1976, Science.

Analysis of regulatory regions in the COL1A1 gene responsible for 1,25‐dihydroxyvitamin D3‐mediated transcriptional repression in osteoblastic cells

D. Rowe, J. Pike, D. Pavlin, 1994, Journal of cellular biochemistry.

Osteopenia in transgenic mice with osteoblast-targeted expression of the inducible cAMP early repressor.

G. Gronowicz, Fei-peng Liu, B. Kream, 2008, Bone.

Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice

D. Rowe, P. Krebsbach, D. Pavlin, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effect of heparin on bone formation in cultured fetal rat calvaria

M. Hurley, G. Gronowicz, B. Kream, 1990, Calcified Tissue International.

Isolation and characterization of the rat alpha 1(I) collagen promoter. Regulation by 1,25-dihydroxyvitamin D.

D. Rowe, B. Kream, A. Lichtler, 1989, The Journal of biological chemistry.

Effects of prostaglandin E2 on bone formation in cultured fetal rat calvariae: role of insulin-like growth factor-I.

E. Canalis, T. McCarthy, B. Kream, 1993, Endocrinology.

Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition.

L. Donahue, C. Ackert-Bicknell, M. Adamo, 2006, Endocrinology.

Intestinal cytosol binders of 1,25-dihydroxyvitamin D and 25-hydroxyvitamin D.

H. DeLuca, J. Eisman, R. Reynolds, 1976, Archives of biochemistry and biophysics.

Isolation and characterization of the rat alpha 1(I) collagen promoter. Regulation by vitamin D.

D. Rowe, B. Kream, A. Lichtler, 1994, Journal of Biological Chemistry.