D. Layman

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Breast tumors induced by N‐methyl‐N‐nitrosourea are damaging to bone strength, structure, and mineralization in the absence of metastasis in rats

E. Evans, C. Moulton, A. W. Wagoner Johnson, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The influence of starvation and refeeding on the lipoprotein lipase activity of skeletal muscle and adipose tissue of lean and obese Zucker rats.

P. Bechtel, D. Quig, D. Layman, 1983, The Journal of nutrition.

Preexercise meal composition alters plasma large neutral amino acid responses during exercise and recovery.

R. Boileau, D. Layman, G. Paul, 1996, The American journal of clinical nutrition.

Protein in optimal health: heart disease and type 2 diabetes.

R. Krauss, F. Nuttall, P. Clifton, 2008, The American journal of clinical nutrition.

The Role of Models in Metabolic Research: a Physiological Perspective

R. Wolfe, J. Rosenblatt, D. Layman, 1988 .

Increased ratio of dietary carbohydrate to protein shifts the focus of metabolic signaling from skeletal muscle to adipose

S. Devkota, D. Layman, 2011, Nutrition & metabolism.

Dietary protein impact on glycemic control during weight loss.

D. Layman, J. Baum, 2004, The Journal of nutrition.

Protein Quantity and Quality at Levels above the RDA Improves Adult Weight Loss

D. Layman, 2004, Journal of the American College of Nutrition.

Moderate carbohydrate, moderate protein weight loss diet reduces cardiovascular disease risk compared to high carbohydrate, low protein diet in obese adults: A randomized clinical trial

E. Evans, D. Layman, Denise A Walker Lasker, 2008, Nutrition & metabolism.

A diet high in protein, dairy, and calcium attenuates bone loss over twelve months of weight loss and maintenance relative to a conventional high-carbohydrate diet in adults.

E. Evans, Xuming He, P. Kris-Etherton, 2008, The Journal of nutrition.

Optimizing Adult Protein Intake During Catabolic Health Conditions

S. Phillips, D. Layman, D. Paddon-Jones, 2020, Advances in nutrition.

Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle.

G. Freund, T. Anthony, J. O'Connor, 2005, American journal of physiology. Endocrinology and metabolism.

Protein quality assessment: impact of expanding understanding of protein and amino acid needs for optimal health.

D. Tomé, G. Schaafsma, D. Layman, 2008, The American journal of clinical nutrition.

Dietary Guidelines should reflect new understandings about adult protein needs

D. Layman, 2009, Nutrition & metabolism.

Excretion of 3-methylhistidine and hydroxyproline following acute weight-training exercise.

R. Boileau, C. Horswill, D. Layman, 1988, International journal of sports medicine.

A reduced carbohydrate, increased protein diet stabilizes glycemic control and minimizes adipose tissue glucose disposal in rats.

Manabu T. Nakamura, G. Freund, D. Layman, 2006, The Journal of nutrition.

The Emerging Role of Dairy Proteins and Bioactive Peptides in Nutrition and Health Dietary Protein Impact on Glycemic Control during Weight Loss 1

D. Layman, J. Baum, 2004 .

Increased dietary protein modifies glucose and insulin homeostasis in adult women during weight loss.

D. Layman, Harn Shiue, J. Baum, 2003, The Journal of nutrition.

The influence of early nutrition on the serum cholesterol of the adult rat.

P. Kris-Etherton, D. Layman, I. Frantz, 1979, The Journal of nutrition.

Glutathione peroxidase activity in iron-deficient rats.

D. Layman, R. Bell, Y. H. Lee, 1981, The Journal of nutrition.

3-kinase activity in rat skeletal muscle Leucine reduces the duration of insulin-induced PI

E. Volpi, M. Drummond, E. Glynn, 2011 .

Nitrogen metabolism at chronic low energy intakes

D. Layman, M. Sika, 1993 .

Effects of protein intake and gender on body composition changes: a randomized clinical weight loss trial

E. Evans, P. Kris-Etherton, M. Thorpe, 2012, Nutrition & Metabolism.

Meat intake's influence on body fatness cannot be assessed without measurement of body fat.

A. Astrup, M. Westerterp-Plantenga, P. Clifton, 2010, The American journal of clinical nutrition.

Induction of autophagy through the activating transcription factor 4 (ATF4)-dependent amino acid response pathway in maternal skeletal muscle may function as the molecular memory in response to gestational protein restriction to alert offspring to maternal nutrition

Huan Wang, Yuan-Xiang Pan, Dan Zhou, 2015, British Journal of Nutrition.

Meal Distribution of Dietary Protein and Leucine Influences Long-Term Muscle Mass and Body Composition in Adult Rats.

C. Moulton, D. Layman, L. Norton, 2017, The Journal of nutrition.

Leucine dense whey proteins

D. Layman, Jacob M. Wilson, L. Norton, 2011 .

Cellular development of skeletal muscle of rats during recovery from prolonged undernutrition.

D. Layman, S. Glore, 1987, The Journal of nutrition.

Role of leucine in protein metabolism during exercise and recovery.

D. Layman, 2002, Canadian journal of applied physiology = Revue canadienne de physiologie appliquee.

Effects of leucine on in vitro protein synthesis and degradation in rat skeletal muscles.

D. Layman, S. O. Hong, 1984, The Journal of nutrition.

Response of Skeletal Muscle Protein Synthesis and Breakdown to Levels of Dietary Protein and Fat During Growth in Weanling Rats

D. Layman, R. Durschlag, Colleen K. Smith, 1982 .

Gut microbiota mediate the FGF21 adaptive stress response to chronic dietary protein-restriction in mice

S. Devkota, J. Gilbert, Connie W. Y. Ha, 2021, Nature Communications.

Whole body and plasma protein synthesis in exercise and recovery in human subjects.

R. Wolfe, F. Jahoor, D. Layman, 1990, The American journal of physiology.

Egg Protein as a Source of Power, Strength, and Energy

N. Rodriguez, D. Layman, 2009 .

Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise.

D. Layman, L. Norton, 2006, The Journal of nutrition.

Branched-Chain Amino Acids in Exercise Leucine Regulates Translation Initiation of Protein Synthesis in Skeletal Muscle after Exercise 1 , 2

D. Layman, L. Norton, 2005 .

Lipoprotein lipase activities in exercise-trained rats isocalorically fed high or low fat diets

Cecelia M. Brown, D. Quig, D. Layman, 1987 .

Branched-Chain Amino Acids : Metabolism , Physiological Function , and Application Potential Importance of Leucine in Treatment of Obesity and the Metabolic Syndrome 1 – 3

D. Layman, Denise A Walker, D. Walker, 2005 .

Skeletal muscle growth in lean and obese Zucker rats.

D. Layman, R. Durschlag, 1983, Growth.

Dietary Protein Distribution Positively Influences 24-h Muscle Protein Synthesis in Healthy Adults123

M. Sheffield-Moore, K. English, D. Layman, 2014, The Journal of nutrition.

Iron deficiency impairs protein synthesis in immune tissues of rat pups.

D. Layman, A. R. Sherman, L. Rosch, 1987, The Journal of nutrition.

Changes in aerobic and anaerobic metabolism in rat cardiac and skeletal muscles after total or partial dietary restrictions.

D. Layman, P. Hegarty, P. Swan, 1981, The Journal of nutrition.

The leucine content of a complete meal directs peak activation but not duration of skeletal muscle protein synthesis and mammalian target of rapamycin signaling in rats.

T. Anthony, P. Garlick, D. Layman, 2009, The Journal of nutrition.

synthesis during recovery from exercise Availability of eIF4E regulates skeletal muscle protein

S. Kimball, L. Jefferson, D. Layman, 2012 .

Oat, wheat or corn cereal ingestion before exercise alters metabolism in humans.

R. Boileau, D. Layman, G. Paul, 1996, The Journal of nutrition.

Leucine supplementation enhances skeletal muscle recovery in rats following exercise.

T. Anthony, D. Layman, J. Anthony, 1999, The Journal of nutrition.

Leucine or carbohydrate supplementation reduces AMPK and eEF2 phosphorylation and extends postprandial muscle protein synthesis in rats.

C. Proud, T. Anthony, C. Moulton, 2011, American journal of physiology. Endocrinology and metabolism.

Muscle catabolism in lean and obese zucker rats fed a very low calorie diet

P. Bechtel, J. Novakofski, D. Layman, 1992 .

Adaptations of adult lean and obese zucker rats during food restriction

P. Bechtel, D. Layman, S. Glore, 1988 .

Leucine content of dietary proteins is a determinant of postprandial skeletal muscle protein synthesis in adult rats

C. Moulton, P. Garlick, D. Layman, 2012, Nutrition & Metabolism.

Dairy bioactive proteins and peptides: a narrative review

N. Auestad, D. Layman, 2021, Nutrition reviews.

Eating patterns, diet quality and energy balance A perspective about applications and future directions for the food industry

D. Layman, 2014, Physiology & Behavior.

Total-body electrical conductivity (TOBEC): relationship to estimates of muscle mass, fat-free weight, and lean body mass.

R. Boileau, C. Horswill, D. Layman, 1989, The American journal of clinical nutrition.

The role of leucine in weight loss diets and glucose homeostasis.

D. Layman, 2003, The Journal of nutrition.

Applications for α-lactalbumin in human nutrition

J. Fernstrom, D. Layman, B. Lönnerdal, 2018, Nutrition reviews.

Amount and type of protein influences bone health.

R. Heaney, Donald K Layman, D. Layman, 2008, The American journal of clinical nutrition.

A high protein moderate carbohydrate diet fed at discrete meals reduces early progression of N-methyl-N-nitrosourea-induced breast tumorigenesis in rats

S. Devkota, K. Singletary, C. Moulton, 2010, Nutrition & metabolism.

Assessing the Role of Cattle in Sustainable Food Systems

D. Layman, 2018, Nutrition Today.

The effect of age on protein synthesis and ribosome aggregation to messenger RNA in rat liver.

A. Richardson, G. Ricca, D. Layman, 1976, Archives of biochemistry and biophysics.

Cellular Development of Skeletal Muscle during Early Periods of Nutritional Restriction and Subsequent Rehabilitation

D. Layman, S. Glore, 1983, Pediatric Research.

Defining meal requirements for protein to optimize metabolic roles of amino acids

G. Brinkworth, B. Rasmussen, T. Anthony, 2015, The American journal of clinical nutrition.

Comparison of morphological and biochemical parameters of growth in rat skeletal muscles.

D. Layman, P. Hegarty, P. Swan, 1980, Journal of anatomy.

Loss of tissues in female rats subjected to food restriction during lactation or during both gestation and lactation.

D. Layman, S. Glore, 1985, The Journal of nutrition.

The effect of acute dietary restriction on muscle fibre number in weanling rats

D. Layman, P. Hegarty, P. Swan, 1981, British Journal of Nutrition.

Important Concepts in Protein Nutrition, Aging, and Skeletal Muscle: Honoring Dr Douglas Paddon-Jones (1969-2021) by Highlighting His Research Contributions.

Wayne N. Campbell, Stuart M Phillips, D. Layman, 2023, The Journal of nutrition.

postprandial muscle protein synthesis in rats AMPK and eEF 2 phosphorylation and extends Leucine or carbohydrate supplementation reduces

C. Proud, T. Anthony, C. Moulton, 2012 .

Symposium : Dairy Product Components and Weight Regulation The Role of Leucine in Weight Loss Diets and Glucose Homeostasis 1 , 2

D. Layman, 2002 .

Availability of eIF4E regulates skeletal muscle protein synthesis during recovery from exercise.

S. Kimball, L. Jefferson, D. Layman, 1998, American journal of physiology. Cell physiology.

Dietary protein and exercise have additive effects on body composition during weight loss in adult women.

R. Boileau, E. Evans, D. Layman, 2005, The Journal of nutrition.

A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women.

R. Boileau, J. Painter, Donald K Layman, 2003, The Journal of nutrition.

Time course changes in IGFBP-1 after treadmill exercise and postexercise food intake in rats.

T. Anthony, M. Lewitt, S. Donovan, 2001, American journal of physiology. Endocrinology and metabolism.

The effects of a higher protein intake during energy restriction on changes in body composition and physical function in older women.

Curtis L. Johnson, Curtis L Johnson, Dimitrios C Karampinos, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Protein metabolic roles in treatment of obesity

S. Devkota, D. Layman, 2010, Current opinion in clinical nutrition and metabolic care.

Potential importance of leucine in treatment of obesity and the metabolic syndrome.

D. Layman, D. Walker, 2006, The Journal of nutrition.

Growth hormone promotes somatic and skeletal muscle growth recovery in rats following chronic protein-energy malnutrition.

S. Donovan, D. Layman, T. A. Gautsch, 1999, The Journal of nutrition.

Branched-chain ketoacid ingestion: an alternative to efficiently increase skeletal muscle protein synthesis.

D. Layman, D. Paddon-Jones, 2019, American Journal of Clinical Nutrition.

Nutrition & Metabolism Dietary Guidelines Should Reflect New Understandings about Adult Protein Needs New Concepts about Protein for the Dietary Guidelines

D. Layman, 2022 .

Leucine contents of isonitrogenous protein sources predict post prandial skeletal muscle protein synthesis in rats fed a complete meal

P. Garlick, D. Layman, L. Norton, 2009 .

Protein as a Functional Food Ingredient for Weight Loss and Maintaining Body Composition

R. Wildman, D. Layman, Jennifer Seyler, 2006 .

Effects of prolonged meal-feeding on the body composition of adult rats

D. Layman, S. Glore, J. G. Link, 1984 .

A moderate-protein diet produces sustained weight loss and long-term changes in body composition and blood lipids in obese adults.

E. Evans, P. Kris-Etherton, A. Griel, 2009, The Journal of nutrition.

Response of the IGF-I system to prolonged undernutrition and its involvement in somatic and skeletal muscle growth retardation in rats.

S. Donovan, D. Layman, T. A. Gautsch, 1998, Growth, development, and aging : GDA.

Availability of eIF4E regulates skeletal muscle protein synthesis during recovery from exercise.

S. Kimball, L. Jefferson, D. Layman, 1998, The American journal of physiology.

An in vivo examination of the effects of leucine on skeletal muscle protein synthesis in the fasting rat

Soon-Kwang Hong, D. Layman, G. J. Wibert, 1991 .

Human Nutrition and Metabolism Dietary Protein and Exercise Have Additive Effects on Body Composition during Weight Loss in Adult Women 1 , 2

R. Boileau, E. Evans, D. Layman, 2005 .

Lipoprotein lipase activity and chylomicron clearance in rats fed a high fat diet.

C. M. Brown, D. Layman, Cecelia M. Brown, 1988, The Journal of nutrition.

Response of glutathione peroxidase and catalase to excess dietary iron in rats.

H. W. Norton, D. Layman, R. Bell, 1981, The Journal of nutrition.

Protein Nutrition, Meal Timing, and Muscle Health

D. Layman, 2013 .

Nutrition and fitness: How Much Protein Does an Athlete Need?

D. Layman, 1987 .

Equal Distributions of Dietary Protein Throughout the Day Maximizes Rat Skeletal Muscle Mass

C. Moulton, P. Garlick, D. Layman, 2010 .

Meal Distribution of Dietary Protein and Leucine Influences Long-Term Muscle Mass and Body Composition in Adult Rats.

C. Moulton, D. Layman, L. Norton, 2017, The Journal of nutrition.

Dietary protein holds positive and negative effects on bone health in rats

E. Evans, C. Moulton, A. W. Wagoner Johnson, 2009 .

Sample site selection for tracer studies applying a unidirectional circulatory approach.

R. Wolfe, D. Layman, 1987, The American journal of physiology.

Isonitrogenous protein sources with different leucine contents differentially effect translation initiation and protein synthesis in skeletal muscle

P. Garlick, D. Layman, L. Norton, 2008 .

Post-Meal Responses of Elongation Factor 2 (eEF2) and Adenosine Monophosphate-Activated Protein Kinase (AMPK) to Leucine and Carbohydrate Supplements for Regulating Protein Synthesis Duration and Energy Homeostasis in Rat Skeletal Muscle

T. Anthony, C. Moulton, P. Garlick, 2012, Nutrients.

Impacts of protein quantity and distribution on body composition

D. Layman, 2024, Frontiers in nutrition.