Guan-Hua Lai

Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3.

Guan-Hua Lai, Zichen Zhang, Alphonse E Sirica, 2003, Molecular cancer therapeutics.