K. Furukawa

发表

Identification of lysine 15 at the active site in Escherichia coli glycogen synthase. Conservation of Lys-X-Gly-Gly sequence in the bacterial and mammalian enzymes.

M. Inouye, J. Preiss, M. Tagaya, 1990, The Journal of biological chemistry.

Role of the conserved Lys-X-Gly-Gly sequence at the ADP-glucose-binding site in Escherichia coli glycogen synthase.

M. Tagaya, K. Tanizawa, T. Fukui, 1993, The Journal of biological chemistry.

Identification of Lys277 at the active site of Escherichia coli glycogen synthase. Application of affinity labeling combined with site-directed mutagenesis.

M. Tagaya, K. Tanizawa, T. Fukui, 1994, The Journal of biological chemistry.

Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus.

Yoshimasa Takahashi, M. Shimoda, M. Nomura, 2013, International immunology.

Cloning and nucleotide sequences of histidase and regulatory genes in the Bacillus subtilis hut operon and positive regulation of the operon

K. Furukawa, M. Oda, A. Sugishita, 1988, Journal of bacteriology.

Analysis of the transcriptional activity of the hut promoter in Bacillus subtilis and identification of a cis‐acting regulatory region associated with catabolite repression downstream from the site of transcription

H. Shoun, T. Hoshino, K. Furukawa, 1992, Molecular microbiology.

Cyclic GMP regulation of the plasma membrane (Ca2+-Mg2+)ATPase in vascular smooth muscle.

H. Nakamura, K. Furukawa, 1987, Journal of biochemistry.

An NMR Biochemical Assay for Fragment-Based Drug Discovery: Evaluation of an Inhibitor Activity on Spermidine Synthase of Trypanosoma cruzi.

K. Yamasaki, K. Furukawa, T. Niimi, 2016, Journal of medicinal chemistry.

Crystal structures of the RNA triphosphatase from Trypanosoma cruzi provide insights into how it recognizes the 5′-end of the RNA substrate

C. Ho, Y. Takagi, K. Furukawa, 2020, The Journal of Biological Chemistry.

Augmented Antibody Response with Premature Germinal Center Regression in CD40L Transgenic Mice

T. Tsubata, T. Tokuhisa, T. Higuchi, 2010, The Journal of Immunology.

Investigation of the Pyrimidine Preference by the c-Myb DNA-binding Domain at the Initial Base of the Consensus Sequence*

A. Sarai, H. Nakamura, M. Oda, 1997, The Journal of Biological Chemistry.

Identification of lysyl and glycyl residues located at the active site in glycogen synthase and their roles in the catalytic reaction

K. Furukawa, 1993 .

T cells specific to hapten carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodies.

M. Oda, S. Ogawa, R. Abe, 2007, International immunology.

The vaso-contractile action of zooxanthellatoxin-B from a marine dinoflagellate is mediated via Ca2+ influx in the rabbit aorta.

H. Nakamura, Y. Ohizumi, A. Murai, 2001, Canadian journal of physiology and pharmacology.

A specific feedback by anti-IgE autoantibodies on the cytokine network in allergy.

S. Miescher, M. Vogel, M. Rudolf, 1993, Agents and actions. Supplements.

Xestoquinone activates skeletal muscle actomyosin ATPase by modification of the specific sulfhydryl group in the myosin head probably distinct from sulfhydryl groups SH1 and SH2.

H. Sakamoto, H. Nakamura, Y. Ohizumi, 1995, Biochemistry.

Conformational analysis of human serum albumin and its non-enzymatic glycation products using monoclonal antibodies.

K. Furukawa, Jin Muraoka, T. Azuma, 2011, Journal of biochemistry.

A Role of the Third Complementarity-determining Region in the Affinity Maturation of an Antibody*

K Furukawa, H. Shirai, H Nakamura, 2001, The Journal of Biological Chemistry.

Junctional amino acids determine the maturation pathway of an antibody.

H. Nakamura, H. Shirai, K. Furukawa, 1999, Immunity.

Fibrinogen Nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer.

J. Takamatsu, S. Iwanaga, H. Saito, 1989, Journal of biochemistry.

Thermodynamics of specific and non-specific DNA binding by the c-Myb DNA-binding domain.

K Furukawa, A. Sarai, H. Nakamura, 1998, Journal of molecular biology.

Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi

Y. Takagi, Motomichi Doi, K. Furukawa, 2019, PLoS neglected tropical diseases.

Strategy for affinity maturation of an antibody with high evolvability to (4-hydroxy-3-nitrophenyl) acetyl hapten.

Takeyuki Shimizu, A. Murakami, I. Yamato, 2007, Molecular immunology.

Kinetic analysis of DNA binding by the c‐Myb DNA‐binding domain using surface plasmon resonance

K Furukawa, A. Sarai, H. Nakamura, 1999, FEBS letters.

Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.

T. Kurosaki, H. Koseki, S. Moriyama, 2013, Immunity.

Crystal structures of FMN‐bound and FMN‐free forms of dihydroorotate dehydrogenase from Trypanosoma brucei

K. Yamasaki, Tomohiko Yamaguchi, T. Kubota, 2018, FEBS open bio.

Thermodynamic and kinetic aspects of antibody evolution during the immune response to hapten.

Masayuki Oda, M. Oda, M. Ishimura, 2003, Molecular immunology.

Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells.

H. Nakamura, Y. Ohizumi, K. Furukawa, 2001, European journal of pharmacology.

BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.

K. Hayashi, D. Kitamura, Mutsumi Yamamoto, 2004, International immunology.

CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP

N. Ito, T. Adachi, T. Tsubata, 2016, The Journal of experimental medicine.

Inositol 1,4,5‐trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle

K. Mikoshiba, Y. Ohmiya, Motomichi Doi, 2016, FEBS open bio.

Identification of indispensable residues for specific DNA-binding in the imperfect tandem repeats of c-Myb R2R3.

K Furukawa, A. Sarai, H. Nakamura, 1997, Protein engineering.

Biological functions and structural biology of Plasmodium falciparum autophagy‐related proteins: The under‐explored options for novel antimalarial drug design

K. Yamasaki, K. Furukawa, M. Ibrahim, 2023, Chemical biology & drug design.

Probing the Active Site in Glycogen Synthase by Affinity Labeling with Nucleotidyl Derivatives of Pyridoxal Phosphate

M. Tagaya, T. Fukui, K. Furukawa, 1991 .

A landscape for the dynamics of an immune response.

K. Furukawa, T. Azuma, A. Furukawa, 2004, Biochemical and biophysical research communications.

Initial repertoire of anti-(4-hydroxy-3-nitrophenylacetyl) antibodies as potential donors for effective affinity maturation.

T. Okajima, K. Furukawa, T. Azuma, 2006, Molecular immunology.

A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy.

H. Nakamura, K. Furukawa, M. Oda, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Biological activities of anti-IgE antibodies.

S. Miescher, M. Vogel, B. Stadler, 1993, International Archives of Allergy and Immunology.

Construction of an artificial tandem protein of the c-Myb DNA-binding domain and analysis of its DNA binding specificity.

A. Sarai, H. Nakamura, K. Furukawa, 1999, Biochemical and biophysical research communications.

Effect of anti-IgE antibodies on Fc epsilonRI-bound IgE.

S. Miescher, M. Vogel, M. Rudolf, 1996, Journal of immunology.

Fragment-Based Drug Discovery for Trypanosoma brucei Glycosylphosphatidylinositol-Specific Phospholipase C through Biochemical and WaterLOGSY-NMR Methods.

K. Yamasaki, T. Yamasaki, K. Furukawa, 2022, Journal of biochemistry.

Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.

T. Kurosaki, H. Koseki, Ryo Shinnakasu, 2013, Immunity.

Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus.

Yoshimasa Takahashi, M. Shimoda, M. Nomura, 2013, International immunology.