C. Beyer

发表

Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control.

J. Hirsch, B. Beer, A. Blume, 1989, Molecular pharmacology.

TTI-237: a novel microtubule-active compound with in vivo antitumor activity.

C. Discafani, J. Gibbons, J. Lucas, 2008, Cancer research.

HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

T. Fojo, R. Andersen, J. Nieman, 2003, Cancer research.

Synthesis and SAR of 6-chloro-4-fluoroalkylamino-2-heteroaryl-5-(substituted)phenylpyrimidines as anti-cancer agents.

N. Zhang, C. Discafani, J. Lucas, 2009, Bioorganic & medicinal chemistry.

A calicheamicin conjugate with a fully humanized anti-MUC1 antibody shows potent antitumor effects in breast and ovarian tumor xenografts.

A. Mountain, C. Beyer, D. Shochat, 2005, Bioconjugate chemistry.

An anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Choice of linker.

I. Bernstein, C. Beyer, D. Flowers, 2002, Bioconjugate chemistry.

Studies of individual amino acid residues of the decapeptide tyrocidine A by proton double-resonance difference spectroscopy in the correlation mode.

J. Dadok, H. Wyssbrod, C. Beyer, 1975, Biochemistry.

A 'dot-immunobinding assay' on nitrocellulose membrane for the determination of the immunoglobulin class of mouse monoclonal antibodies.

C. Beyer, 1984, Journal of immunological methods.

Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells.

C. Discafani, S. Rabindran, G. Krishnamurthy, 2005, Bioorganic & medicinal chemistry letters.

Lymphocyte transformation induced by chemical modification of membrane components. I. Characteristics of the direct and indirect restimulation responses of rat lymph node cells to periodate.

C. Beyer, W. Bowers, 1977, Journal of immunology.

MAC-321, a novel taxane with greater efficacy than paclitaxel and docetaxel in vitro and in vivo.

F. Loganzo, D. Sampath, C. Discafani, 2003, Molecular cancer therapeutics.

2-cyanoaminopyrimidines as a class of antitumor agents that promote tubulin polymerization.

N. Zhang, S. Ayral-Kaloustian, C. Beyer, 2007, Bioorganic & medicinal chemistry letters.

Characterization of ligand binding to mitochondrial benzodiazepine receptors.

J. Hirsch, A. Blume, C. Beyer, 1989, Molecular pharmacology.

Synthesis and SAR of [1,2,4]triazolo[1,5-a]pyrimidines, a class of anticancer agents with a unique mechanism of tubulin inhibition.

Nan Zhang, Judy Lucas, N. Zhang, 2007, Journal of medicinal chemistry.

D-piece modifications of the hemiasterlin analog HTI-286 produce potent tubulin inhibitors.

F. Loganzo, G. Krishnamurthy, L. Greenberger, 2004, Bioorganic & medicinal chemistry letters.

Rat dendritic cells function as accessory cells and control the production of a soluble factor required for mitogenic responses of T lymphocytes.

C. Beyer, J. Labadie, J. O'Brien, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Cathepsin D of mouse leukemia L1210 cells. Unusual intracellular localization and biochemical properties.

C. Beyer, N. Yago, W. Bowers, 1977, Biochimica et biophysica acta.

Preclinical Pharmacologic Evaluation of MST-997, an Orally Active Taxane with Superior In vitro and In vivo Efficacy in Paclitaxel- and Docetaxel-Resistant Tumor Models

Deepak Sampath, Carol Rios, D. Sampath, 2006, Clinical Cancer Research.

Synthesis and biological activity of analogues of the antimicrotubule agent N, β, β-trimethyl-L-phenylalanyl-N1-[(1S, 2E)-3-carboxy-1-isopropylbut-2-enyl]-N1, 3 -dimethyl-L-valinamide (HTI-286)

R. Williamson, F. Loganzo, C. Discafani, 2004 .

Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia.

Irwin Hollander, I. Bernstein, H. Tsou, 2002, Bioconjugate chemistry.

The microtubule-active antitumor compound TTI-237 has both paclitaxel-like and vincristine-like properties

J. Gibbons, S. Ayral-Kaloustian, N. Zhang, 2009, Cancer Chemotherapy and Pharmacology.

Structural requirements for binding and fluorescence enhancement of the fluorescent probe TNS with peptides.

L. Craig, C. Beyer, W. Gibbons, 1973, Nature: New biology.

Periodate and concanavalin A induce blast transformation of rat lymphocytes by an indirect mechanism.

C. Beyer, W. Bowers, 1975, Proceedings of the National Academy of Sciences of the United States of America.

Cell-cell interactions in blast transformation of rat lymphocytes by neuraminidase and galactose oxidase.

M. Kielian, C. Beyer, W. Bowers, 1977, Experimental cell research.

Lymphocyte transformation induced by chemical modification of membrane components. II. Effect of neuraminidase treatment of responder cells on proliferation and cytotoxicity in indirect stimulation.

C. Beyer, W. Bowers, 1978, Journal of immunology.

PERIODATE-INDUCED BLAST TRANSFORMATION IN MIXTURES OF RAT LYMPHOID CELLS

C. Beyer, W. Bowers, 1977 .

Heterogenous tryptophan environments in the cyclic peptides tyrocidines B and C. Phosphorescence studies.

L. Craig, C. Beyer, J. Longworth, 1974, The Journal of biological chemistry.

An anti-MUC1 antibody-calicheamicin conjugate for treatment of solid tumors. Choice of linker and overcoming drug resistance.

Ana T Menendez, L. Greenberger, F. Durr, 2005, Bioconjugate chemistry.

Two Photoaffinity Analogues of the Tripeptide, Hemiasterlin, Exclusively Label α-Tubulin

F. Loganzo, G. Krishnamurthy, A. Zask, 2005 .

Interaction of the fluorescent probe 2-p-toluidinylnaphthalene-6-sulfonate with peptides. Structural requirements for binding and fluorescence enhancement.

L. Craig, C. Beyer, W. Gibbons, 1972, Biochemistry.

Separation of 2,4-dinitrophenylhydrazones into classes by thin-layer chromatography on zinc carbonate

C. Beyer, T. E. Kargl, 1972 .

Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286).

R. Williamson, F. Loganzo, C. Discafani, 2004, Journal of medicinal chemistry.

Cathepsin D of Rat Thoracic Duct Lymphocytes: Unusual Intracellular Localization and Biochemical Properties

C. Beyer, J. Panagides, N. Yago, 1977 .