M. Read

发表

Postinduction transcriptional repression of E-selectin and vascular cell adhesion molecule-1.

M. Gerritsen, T. Collins, M. Read, 1996, Journal of immunology.

NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation

Amyj . Williams, T. Collins, M. Whitley, 1994, The Journal of experimental medicine.

Salicylates inhibit I kappa B-alpha phosphorylation, endothelial-leukocyte adhesion molecule expression, and neutrophil transmigration.

F. Luscinskas, T. Collins, M. Read, 1996, Journal of immunology.

Nedd8 Modification of Cul-1 Activates SCFβTrCP-Dependent Ubiquitination of IκBα

V. Chau, J. Brownell, V. Palombella, 2000, Molecular and Cellular Biology.

Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells.

C. Peng, Yiguo Hu, Shaoguang Li, 2007, Blood.

Chemoresistance: Impact of Nuclear Factor (NF)-κB Inhibition by Small Interfering RNA

M. Read, O. P. Veiby, 2004, Clinical Cancer Research.

Enhanced Chemosensitivity to Irinotecan by RNA Interference-Mediated Down-Regulation of the NF-B p 65 Subunit

M. Read, O. P. Veiby, 2004 .

A new model of cancer cachexia: contribution of the ubiquitin-proteasome pathway.

A. Goldberg, P. Elliott, L. Dick, 1999, American journal of physiology. Endocrinology and metabolism.

A new model of cancer cachexia: contribution of the ubiquitin-proteasome pathway.

A. Goldberg, P. Elliott, L. Dick, 1999, The American journal of physiology.

Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity

J. Kutok, M. Read, J. Proctor, 2014, PloS one.

T. Maniatis, T. Collins, M. Whitley, 1994, Molecular and cellular biology.

Nedd8 Modification of Cul-1 Activates SCF

V. Chau, J. Brownell, V. Palombella, 2000 .

Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells.

M. Read, J. Hawiger, S. R. Cordle, 1993, The Journal of biological chemistry.

Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.

James R. Porter, J. Sydor, M. Foley, 2008, Journal of medicinal chemistry.

NF-gB and Ir~B~: An Inducible Regulatory System

Amyj . Williams, T. Collins, M. Whitley, 1994 .

Cell-free pool of CD14 mediates activation of transcription factor NF-kappa B by lipopolysaccharide in human endothelial cells.

M. Read, R. Veach, J. Hawiger, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional regulation of endothelial cell adhesion molecules : NF-icB and cytokine-inducible enhancers

T. Maniatis, T. Collins, D. Thanos, 2004 .

Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).

Jeanne A. Ferguson, J. Sydor, J. Adams, 2009, Journal of medicinal chemistry.

Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/lpr mouse model of systemic lupus erythematosus

Samuel K. Shimp, C. Reilly, M. Rylander, 2012, Cellular and Molecular Immunology.

Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90

Jie Ge, James R. Porter, J. Sydor, 2006, Proceedings of the National Academy of Sciences.

Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer

A. Jimeno, M. Hidalgo, A. Pandey, 2008, Molecular Cancer Therapeutics.

Tumor Necrosis Factor α-Induced E-selectin Expression Is Activated by the Nuclear Factor-κB and c-JUN N-terminal Kinase/p38 Mitogen-activated Protein Kinase Pathways*

T. Collins, J. Best, M. Whitley, 1997, The Journal of Biological Chemistry.

The Hedgehog Signaling Pathway in Cancer Pathogenesis and Therapy

V. Palombella, M. Read, 2012 .

Endothelial interferon regulatory factor 1 cooperates with NF-kappa B as a transcriptional activator of vascular cell adhesion molecule 1

T. Maniatis, T. Collins, D. Thanos, 1995, Molecular and cellular biology.

The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression.

T. Maniatis, F. Luscinskas, T. Collins, 1995, Immunity.

Ubiquitination of IkBa

V. Chau, J. Brownell, V. Palombella, 2000 .

adhesion molecule 1 . transcriptional activator of vascular cell cooperates with NF-kappa B as a Endothelial interferon regulatory factor 1

T. Maniatis, T. Collins, R. Pine, 1995 .

An intact NEDD8 pathway is required for Cullin‐dependent ubiquitylation in mammalian cells

W. Kaelin, William Y. Kim, M. Ohh, 2002, EMBO reports.

New developments in the discovery of small molecule Hedgehog pathway antagonists.

M. Tremblay, M. Read, Margaret A Read, 2010, Current opinion in chemical biology.

The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway

Jeanne A. Ferguson, J. Sydor, J. Adams, 2013, Xenobiotica; the fate of foreign compounds in biological systems.

570 POSTER Activity of IPI-926, a novel inhibitor of the HH pathway, in subcutaneous and orthotopically implanted xenograft tumors that express SHH ligand

J. Sydor, V. Palombella, Z. Oaks, 2008 .

Abstract LB-380: Direct targeting of the Hedgehog pathway in primary chondrosarcoma xenografts with the Smoothened inhibitor IPI-926

B. Alman, J. Wunder, H. Whetstone, 2011 .

Transcriptional regulation of endothelial cell adhesion molecules: NF‐κB and cytokine‐inducible enhancers

T. Maniatis, T. Collins, D. Thanos, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Chemoresistance: Impact of Nuclear Factor (NF)-κB Inhibition by Small Interfering RNA

M. Read, O. P. Veiby, 2004, Clinical Cancer Research.

Abstract 5045: The Hh inhibitor IPI-926 inhibits relapse of a non-small cell lung cancer xenograft model following treatment with an EGF-R targeted tyrosine kinase inhibitor

M. Read, J. Macdougall, Kerry F White, 2010 .