F Tang

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors.

Cherrington, R A Blake, S. Hubbard, 2000, Cancer research.

Identification of substituted 3-[(4,5,6, 7-tetrahydro-1H-indol-2-yl)methylene]-1,3-dihydroindol-2-ones as growth factor receptor inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rbeta tyrosine kinases.

S. Hubbard, G. Mcmahon, L. Sun, 2000, Journal of medicinal chemistry.

Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases.

G. Mcmahon, L. Sun, C. Tang, 1999, Journal of medicinal chemistry.

Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases.

G. Mcmahon, L. Sun, C. Tang, 1998, Journal of medicinal chemistry.