M. Harada

发表

ERK and p38 MAPK, but not NF-&kgr;B, Are Critically Involved in Reactive Oxygen Species–Mediated Induction of IL-6 by Angiotensin II in Cardiac Fibroblasts

M. Suematsu, S. Ogawa, K. Fukuda, 2001, Circulation research.

cDNA cloning and gene expression of human type Ialpha cGMP-dependent protein kinase.

K. Nakao, N. Tamura, H. Itoh, 1996, Hypertension.

Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes.

K. Nakao, K. Tanimoto, Yoshihiko Saito, 2006, Journal of molecular and cellular cardiology.

Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes.

I. Kishimoto, Y. Miyamoto, I Kishimoto, 2000, Journal of molecular and cellular cardiology.

Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes.

K. Nakao, A. Yoshimura, K. Tanimoto, 2005, Journal of molecular and cellular cardiology.

SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo.

K. Nakao, A. Yoshimura, K. Tanimoto, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Endothelin-1 and cardiotrophin-1 induce brain natriuretic peptide gene expression by distinct transcriptional mechanisms.

N. Tamura, I. Masuda, O. Nakagawa, 1998, Journal of cardiovascular pharmacology.

Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro.

I. Masuda, O. Nakagawa, Y. Miyamoto, 1999, Circulation.

Cardiac natriuretic peptides inhibit TRPC6-mediated prohypertrophic signaling through cGMP-PKG pathway

K. Nakao, M. Nishida, Y. Mori, 2009, BMC Pharmacology.

Vasodilator therapy with hydralazine induces angiotensin AT2 receptor‐mediated cardiomyocyte growth in mice lacking guanylyl cyclase‐A

I. Kishimoto, M. Harada, Y. Saito, 2010, British journal of pharmacology.

Interaction of myocytes and nonmyocytes is necessary for mechanical stretch to induce ANP/BNP production in cardiocyte culture.

H. Itoh, I. Masuda, O. Nakagawa, 1998, Journal of cardiovascular pharmacology.

Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A

Hideki Uosaki, C. Mummery, K. Nakao, 2011, PloS one.

Effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, fluvastatin, on coronary spasm after withdrawal of calcium-channel blockers.

M. Horie, K. Kugiyama, S. Hokimoto, 2008, Journal of the American College of Cardiology.

Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy

K. Nakao, K. Ueshima, T. Nishikimi, 2013, British journal of pharmacology.

Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death.

K. Nakao, M. Murakami, K. Ueshima, 2009, American journal of physiology. Heart and circulatory physiology.

Determination of the B-type natriuretic peptide level as a criterion for abnormalities in Japanese individuals in routine clinical practice: the J-ABS Multi-Center Study (Japan Abnormal BNP Standard).

K. Nakao, K. Ueshima, M. Kawai, 2013, Internal medicine.

Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation.

K. Nakao, A. Fukamizu, I. Kishimoto, 2007, Circulation journal : official journal of the Japanese Circulation Society.

Effects of cardiotrophin-1 on hemodynamics and endocrine function of the heart.

I. Masuda, I. Kishimoto, T. Nishikimi, 2000, American journal of physiology. Heart and circulatory physiology.

Possible involvement of endothelin-1 in cardioprotective effects of benidipine.

K. Nakao, O. Nakagawa, M. Harada, 2000, Hypertension research : official journal of the Japanese Society of Hypertension.

NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function

K. Nakao, A. Noma, M. Horie, 2003, The EMBO journal.

Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A.

K. Nakao, A. Fukamizu, K. Tanimoto, 2004, Endocrinology.

Guanylyl Cyclase-A Inhibits Angiotensin II Type 1A Receptor-Mediated Cardiac Remodeling, an Endogenous Protective Mechanism in the Heart

K. Nakao, A. Fukamizu, K. Tanimoto, 2002, Circulation.

Inhibitory Effect of Natriuretic Peptides on Aldosterone Synthase Gene Expression in Cultured Neonatal Rat Cardiocytes

K. Nakao, H. Kurihara, H. Ogawa, 2003, Circulation.

Nitric oxide-mediated vasodilatation is decreased in forearm resistance vessels in patients with coronary spastic angina.

K. Kugiyama, R. Tsunoda, H. Ogawa, 2001, Japanese circulation journal.

p300 Plays a Critical Role in Maintaining Cardiac Mitochondrial Function and Cell Survival in Postnatal Hearts

K. Nakao, M. Takano, M. Murakami, 2009, Circulation research.

Overexpression of Brain Natriuretic Peptide Facilitates Neutrophil Infiltration and Cardiac Matrix Metalloproteinase-9 Expression After Acute Myocardial Infarction

K. Nakao, N. Tamura, K. Tanimoto, 2004, Circulation.

Fibronectin signaling stimulates BNP gene transcription by inhibiting neuron-restrictive silencer element-dependent repression.

K. Nakao, Y. Naruse, I. Kishimoto, 2002, Cardiovascular research.

Angiotensin II-induced ventricular hypertrophy and extracellular signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation.

K. Nakao, I. Kishimoto, Yoshihiko Saito, 2003, Hypertension research : official journal of the Japanese Society of Hypertension.

Angiotensin II Type 2 Receptor Deficiency Exacerbates Heart Failure and Reduces Survival After Acute Myocardial Infarction in Mice

K. Nakao, K. Tanimoto, M. Iwai, 2003, Circulation.

A heart-specific increase in cardiotrophin-1 gene expression precedes the establishment of ventricular hypertrophy in genetically hypertensive rats.

I. Masuda, O. Nakagawa, T. Hosoya, 1999, Journal of hypertension.

The effects of the selective ROCK inhibitor, Y27632, on ET‐1‐induced hypertrophic response in neonatal rat cardiac myocytes – possible involvement of Rho/ROCK pathway in cardiac muscle cell hypertrophy

K. Nakao, N. Tamura, O. Nakagawa, 1999, FEBS letters.

cDNA cloning of rat cardiotrophin-1 (CT-1): augmented expression of CT-1 gene in ventricle of genetically hypertensive rats.

K. Nakao, I. Masuda, O. Nakagawa, 1996, Biochemical and biophysical research communications.

The Neuron-Restrictive Silencer Element–Neuron-Restrictive Silencer Factor System Regulates Basal and Endothelin 1-Inducible Atrial Natriuretic Peptide Gene Expression in Ventricular Myocytes

K. Nakao, Y. Naruse, I. Kishimoto, 2001, Molecular and Cellular Biology.

Effect of interleukin-1 beta on cardiac hypertrophy and production of natriuretic peptides in rat cardiocyte culture.

K. Nakao, O. Nakagawa, H. Yasue, 1999, Journal of molecular and cellular cardiology.

The heart is a source of circulating cardiotrophin-1 in humans.

I. Kishimoto, H. Yasue, M. Harada, 2000, Biochemical and biophysical research communications.

Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a -786T-->C mutation associated with coronary spastic angina.

K. Kangawa, I. Kishimoto, H. Yasue, 2000, Human molecular genetics.

Roles of natriuretic peptides in heart failure.

H. Itoh, I. Masuda, O. Nakagawa, 1996, Journal of cardiac failure.

Role of cardiac nonmyocytes in cyclic mechanical stretch-induced myocyte hypertrophy.

H. Itoh, I. Masuda, O. Nakagawa, 1997, Heart and vessels.

Salacia oblonga root decreases cardiac hypertrophy in Zucker diabetic fatty rats: inhibition of cardiac expression of angiotensin II type 1 receptor

Yuhao Li, Y. Qi, T. H. Huang, 2008, Diabetes, obesity & metabolism.

Retrograde percutaneous coronary intervention for acute myocardial infarction following blunt chest trauma

H. Okumura, M. Harada, Mikiko Mikuri, 2018, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

GENE REGULATION OF BRAIN NATRIURETIC PEPTIDE IN CARDIOCYTE HYPERTROPHY BY α1‐ADRENERGIC STIMULATION

H. Itoh, O. Nakagawa, K. Nakao, 1995, Clinical and experimental pharmacology & physiology. Supplement.

Guanylyl cyclase-A inhibits angiotensin II type 2 receptor-mediated pro-hypertrophic signaling in the heart.

K. Nakao, M. Horiuchi, I. Kishimoto, 2009, Endocrinology.

RT-PCR for CYP 11 B 2 and GAPDH : Design of Primers and Probes

K. Nakao, H. Kurihara, H. Ogawa, 2003 .

Lack of association between T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene and essential hypertension.

K. Nakao, I. Kishimoto, H. Yasue, 2000, Hypertension research : official journal of the Japanese Society of Hypertension.

Association of CT Dinucleotide Repeat Polymorphism in the 5′-Flanking Region of the Guanylyl Cyclase (GC)-A Gene with Essential Hypertension in the Japanese

K. Nakao, K. Kangawa, I. Kishimoto, 2008, Hypertension Research.

Yukio Hypertension Endothelial Nitric Oxide Synthase Gene Is Positively Associated With Essential

K. Nakao, H. Itoh, I. Masuda, 1998 .

Images in cardiovascular medicine. Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance.

K. Nakao, E. Tadamura, K. Hosoda, 2007, Circulation.

Endothelial nitric oxide synthase gene is positively associated with essential hypertension.

H. Itoh, I. Masuda, T. Akamizu, 1998, Hypertension.

Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-kappaB activation and alleviates myocardial ischemia/reperfusion injury.

D. Garbers, G. Takemura, I. Kishimoto, 2001, The Journal of clinical investigation.

Urocortin, a newly identified corticotropin-releasing factor-related mammalian peptide, stimulates atrial natriuretic peptide and brain natriuretic peptide secretions from neonatal rat cardiomyocytes.

K. Nakao, O. Nakagawa, T. Ebisawa, 1998, Biochemical and biophysical research communications.

Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 Is Involved in gp130 Resistance in Cardiovascular System in Rat Treated With Cardiotrophin-1 In Vivo

K. Nakao, A. Yoshimura, I. Masuda, 2001, Circulation research.

Cardiac tamponade caused by uremic pericarditis in a patient with endstage renal disease due to diabetic nephropathy

K. Nakao, H. Yokoi, M. Mukoyama, 2007 .

cDNA Cloning and Gene Expression of Human Type Iα cGMP-Dependent Protein Kinase

K. Nakao, N. Tamura, H. Itoh, 1996 .

Outside-in signalling of fibronectin stimulates cardiomyocyte hypertrophy in cultured neonatal rat ventricular myocytes.

I. Masuda, O. Nakagawa, I. Kishimoto, 2000, Journal of molecular and cellular cardiology.

Aldosterone Induces Angiotensin-Converting-Enzyme Gene Expression in Cultured Neonatal Rat Cardiocytes

O. Nakagawa, Y. Saito, H. Ogawa, 2001, Circulation.

T-Type Ca2+ Channel Blockade Prevents Sudden Death in Mice With Heart Failure

K. Nakao, M. Takano, M. Murakami, 2009, Circulation.

Role of Natriuretic Peptide Receptor Guanylyl Cyclase-A in Myocardial Infarction Evaluated Using Genetically Engineered Mice

K. Nakao, A. Fukamizu, K. Tanimoto, 2005, Hypertension.

Coronary artery aneurysms after adult-onset Kawasaki disease.

M. Gunshin, K. Doi, R. Inokuchi, 2013, Circulation.

Salacia oblonga root improves cardiac lipid metabolism in Zucker diabetic fatty rats: modulation of cardiac PPAR-alpha-mediated transcription of fatty acid metabolic genes.

Yuhao Li, T. H. Huang, J. Yamahara, 2006, Toxicology and applied pharmacology.

Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system.

S. Narumiya, H. Itoh, O. Nakagawa, 1994, Circulation.

Mitochondrial Cardiomyopathy Evaluated With Cardiac Magnetic Resonance

K. Nakao, E. Tadamura, K. Hosoda, 2007 .

Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes.

T. Igaki, H. Itoh, I. Masuda, 1997, Circulation.

Pomegranate Flower Extract Diminishes Cardiac Fibrosis in Zucker Diabetic Fatty Rats: Modulation of Cardiac Endothelin-1 and Nuclear Factor-kappaB Pathways

Yuhao Li, T. H. Huang, J. Yamahara, 2005, Journal of cardiovascular pharmacology.

Effectiveness of delayed enhanced MRI for identification of cardiac sarcoidosis: comparison with radionuclide imaging.

S. Kanao, K. Togashi, T. Saga, 2005, AJR. American journal of roentgenology.

The effects of sarpogrelate on cardiomyocyte hypertrophy.

K. Nakao, M. Harada, K. Ikeda, 2000, Life sciences.

IS040 Positive association between essential hypertension and Glu298Asp polymorphism in the endothelial nitric oxide synthase gene

K. Nakao, I. Masuda, Yoshihiko Saito, 1998 .

Ghrelin strongly stimulates growth hormone release in humans.

K. Nakao, K. Hosoda, H. Ariyasu, 2000, The Journal of clinical endocrinology and metabolism.

The role of cardiovascular research and clinical training in health care reform.

E. Antman, M. Laks, C. Schmid, 1994, Circulation.