J. Wiltsie

发表

A new class of prolylcarboxypeptidase inhibitors, part 2: the aminocyclopentanes.

Michael E. Lassman, Shirly Pinto, J. Lisnock, 2012, Bioorganic & medicinal chemistry letters.

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease

E. Scolnick, J. Hermes, R. Cummings, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Anthrax lethal factor inhibition

E. Scolnick, A. Woods, D. Zaller, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities.

Scott K. Smith, J. Phillips, Jesús Martín, 2012, Bioorganic & medicinal chemistry letters.

Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites

Jeffrey Yuan, D. Schmatz, B. Nare, 2002, The Journal of Biological Chemistry.

Discovery of novel non-steroidal reverse indole mineralocorticoid receptor antagonists.

J. Lisnock, A. Crespo, Gaochao Zhou, 2016, Bioorganic & medicinal chemistry letters.

Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonists.

J. Lisnock, A. Crespo, Gaochao Zhou, 2013, Bioorganic & medicinal chemistry letters.

In Vitro Assays for the Discovery of PCSK9 Autoprocessing Inhibitors

J. Gesell, Shirly Pinto, M. Kavana, 2016, Journal of biomolecular screening.

The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection.

E. Scolnick, A. Woods, D. Zaller, 2006, Bioorganic & Medicinal Chemistry Letters.

Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid Moiety.

Shirly Pinto, J. Lisnock, R. DeVita, 2013, ACS medicinal chemistry letters.

PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products.

Yang Li, Li Zhang, Guy Harris, 2008, Chemistry & biology.

Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moiety.

Shirly Pinto, M. Reibarkh, R. DeVita, 2019, Bioorganic & medicinal chemistry letters.

Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety.

Shirly Pinto, J. Lisnock, R. DeVita, 2014, ACS medicinal chemistry letters.

Heterocyclic core analogs of a direct thrombin inhibitor.

A. Crespo, J. Wiltsie, M. Kurtz, 2014, Bioorganic & medicinal chemistry letters.

Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC).

Shirly Pinto, R. Nargund, P. Váchal, 2019, Bioorganic & medicinal chemistry letters.

Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus.

Scott K. Smith, J. Phillips, Jesús Martín, 2011, Chemistry & biology.

Toxoplasma gondii Cyclic GMP-Dependent Kinase: Chemotherapeutic Targeting of an Essential Parasite Protein Kinase

B. Nare, Suresh B. Singh, P. Liberator, 2002, Eukaryotic Cell.

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

T. Roemer, Xinwei Sher, G. Scapin, 2017, PloS one.

Discovery of benzimidazole oxazolidinediones as novel and selective nonsteroidal mineralocorticoid receptor antagonists.

J. Lisnock, A. Crespo, Gaochao Zhou, 2015, ACS medicinal chemistry letters.

The Bowel as a Focus of Sepsis in Chronic Rheumatic Disease

J. Wiltsie, 1940, Postgraduate medical journal.

Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors.

Shirly Pinto, J. Lisnock, M. Garcia-Calvo, 2014, Bioorganic & medicinal chemistry letters.

Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors.

Shirly Pinto, J. Lisnock, M. Garcia-Calvo, 2013, Bioorganic & medicinal chemistry letters.

A new class of prolylcarboxypeptidase inhibitors, part 1: discovery and evaluation.

Michael E. Lassman, Shirly Pinto, J. Lisnock, 2012, Bioorganic & medicinal chemistry letters.

The role of a parasite-specific allosteric site in the distinctive activation behavior of Eimeria tenella cGMP-dependent protein kinase.

P. Liberator, R. Donald, J. Wiltsie, 2002, Biochemistry.

The Catalytic Flexibility of tRNAIle-lysidine Synthetase Can Generate Alternative tRNA Substrates for Isoleucyl-tRNA Synthetase

J. Wiltsie, S. Salowe, L. Sonatore, 2009, Journal of Biological Chemistry.

Discovery of benzodihydroisofurans as novel, potent, bioavailable and brain-penetrant prolylcarboxypeptidase inhibitors.

Michael E. Lassman, Shirly Pinto, M. Garcia-Calvo, 2012, Bioorganic & medicinal chemistry letters.

Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione series.

J. Lisnock, A. Crespo, Gaochao Zhou, 2014, Bioorganic & medicinal chemistry letters.