F. Ding

发表

Discovery of benzimidazole pyrrolidinyl amides as prolylcarboxypeptidase inhibitors.

Michael E. Lassman, Shirly Pinto, M. Garcia-Calvo, 2011, Bioorganic & medicinal chemistry letters.

Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor.

M. Forrest, Kenneth K. Wu, Q. Deng, 2007, Journal of medicinal chemistry.

Tetrahydro anthranilic acid as a surrogate for anthranilic acid: application to the discovery of potent niacin receptor agonists.

Hong C Shen, J. Tata, S. Colletti, 2008, Bioorganic & medicinal chemistry letters.

Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.

Kenneth K. Wu, Q. Deng, Hong C Shen, 2009, Journal of medicinal chemistry.

Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.

M. Forrest, Kenneth K. Wu, Q. Deng, 2010, Journal of medicinal chemistry.

NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains

J. Anglister, N. Kessler, F. Naider, 2013, The FEBS journal.

Synthesis and biological evaluation of platensimycin analogs.

M. Maccoss, Hong C Shen, S. Soisson, 2009, Bioorganic & medicinal chemistry letters.

Design of Potent IGF1‐R Inhibitors Related to Bis‐azaindoles

C. Venot, W. Metz, F. Ding, 2010, Chemical biology & drug design.

Cross‐Linking of a DOPA‐Containing Peptide Ligand into its G Protein‐Coupled Receptor

J. Becker, F. Naider, F. Ding, 2009, Biochemistry.

Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A.

Hong C Shen, X. Tong, Qing Chen, 2010, Bioorganic & medicinal chemistry letters.

Completely different amyloidogenic potential of nearly identical peptide fragments.

E. Gazit, F. Naider, F. Ding, 2003, Biopolymers.

Anthranilic acid replacements in a niacin receptor agonist.

D. Blom, Hong C Shen, J. Tata, 2010, Bioorganic & medicinal chemistry letters.

Effects of N‐ and C‐terminal addition of oligolysines or native loop residues on the biophysical properties of transmembrane domain peptides from a G‐protein coupled receptor

F. Naider, F. Ding, B. Arshava, 2006, Journal of peptide science : an official publication of the European Peptide Society.

A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors.

J. Berger, Gaochao Zhou, Bei B. Zhang, 2009, Bioorganic & medicinal chemistry letters.

Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors.

J. Berger, Gaochao Zhou, Bei B. Zhang, 2009, Bioorganic & medicinal chemistry letters.

Identification of Residue-to-residue Contact between a Peptide Ligand and Its G Protein-coupled Receptor Using Periodate-mediated Dihydroxyphenylalanine Cross-linking and Mass Spectrometry*

A. Link, J. Becker, F. Naider, 2010, The Journal of Biological Chemistry.

Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold.

A. Swensen, G. Kaczorowski, B. Priest, 2016, Bioorganic & medicinal chemistry letters.

Discovery of MK-8153, a Potent and Selective ROMK Inhibitor and Novel Diuretic/Natriuretic.

K. Samuel, Haifeng Tang, B. Pio, 2021, Journal of medicinal chemistry.

Discovery of a highly potent, selective, and bioavailable soluble epoxide hydrolase inhibitor with excellent ex vivo target engagement.

J. Berger, Gaochao Zhou, Sanjeev Kumar, 2009, Journal of medicinal chemistry.

Study of the binding environment of alpha-factor in its G protein-coupled receptor using fluorescence spectroscopy.

M. Hauser, J. Becker, F. Naider, 2008, The journal of peptide research : official journal of the American Peptide Society.

Alpha-heteroarylation of esters, lactones, amides, and lactams by nucleophilic aromatic substitution.

Hong C Shen, S. Colletti, F. Ding, 2006, Organic letters.

Structure and topology of a peptide segment of the 6th transmembrane domain of the Saccharomyces cerevisae alpha-factor receptor in phospholipid bilayers.

J. Becker, G. Veglia, K. Valentine, 2001, Biopolymers.

Synergism between a CD4-mimic peptide and antibodies elicited by a constrained V3 peptide.

J. Anglister, F. Naider, F. Ding, 2013, AIDS research and human retroviruses.

Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors.

J. Berger, Gaochao Zhou, Sanjeev Kumar, 2009, Bioorganic & medicinal chemistry letters.

ATR-FTIR study of the structure and orientation of transmembrane domains of the Saccharomyces cerevisiae alpha-mating factor receptor in phospholipids.

J. Becker, F. Naider, H. Xie, 2001, Biochemistry.

The Chain Length Dependence of Helix Formation of the Second Transmembrane Domain of a G Protein-coupled Receptor ofSaccharomyces cerevisiae*

J. Becker, F. Naider, N. Verberkmoes, 2002, The Journal of Biological Chemistry.

HIV-1 peptide vaccine candidates: selecting constrained V3 peptides with highest affinity to antibody 447-52D.

B. Mester, J. Anglister, F. Naider, 2009, Biochemistry.

Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast.

F. Naider, M. Dumont, F. Ding, 2013, Protein engineering, design & selection : PEDS.

Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p.

F. Naider, M. Dumont, F. Ding, 2011, Journal of molecular biology.

Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor.

J. Becker, F. Naider, M. Dumont, 2010, Biochemistry.

The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide.

Inbal Ayzenshtat, R. Levy, J. Anglister, 2011, Journal of molecular biology.

Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies.

B. Mester, J. Anglister, F. Naider, 2009, Biochemistry.

Synthesis and Biophysical Characterization of a Multidomain Peptide from a Saccharomyces cerevisiae G Protein-coupled Receptor*

J. Becker, F. Naider, N. Verberkmoes, 2003, Journal of Biological Chemistry.

Orally Bioavailable Macrocyclic Peptide That Inhibits Binding of PCSK9 to the Low Density Lipoprotein Receptor

Jeffrey T. Kuethe, D. Johns, T. Tucker, 2023, Circulation.

Synthesis of a Double Transmembrane Domain Fragment of Ste2p by Native Chemical Ligation

J. Becker, F. Naider, F. Ding, 2007, International Journal of Peptide Research and Therapeutics.

Guided reconstitution of membrane protein fragments

J. Becker, F. Naider, M. Dumont, 2014, Biopolymers.

Synthesis and biophysical analysis of transmembrane domains of a Saccharomyces cerevisiae G protein-coupled receptor.

J. Becker, F. Naider, H. Xie, 2000, Biochemistry.

Probing the binding domain of the Saccharomyces cerevisiae alpha-mating factor receptor with rluorescent ligands.

M. Hauser, J. Becker, F. Naider, 2001, Biochemistry.

Discovery of benzodihydroisofurans as novel, potent, bioavailable and brain-penetrant prolylcarboxypeptidase inhibitors.

Michael E. Lassman, Shirly Pinto, M. Garcia-Calvo, 2012, Bioorganic & medicinal chemistry letters.

A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast.

J. Becker, F. Naider, A. Ćelić, 2004, Biochemistry.

Design of Potent IGF1‐R Inhibitors Related to Bis‐azaindoles

C. Venot, F. Ding, D. Lesuisse, 2010, Chemical biology & drug design.

The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide.

Inbal Ayzenshtat, R. Levy, J. Anglister, 2011, Journal of molecular biology.

Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A.

Hong C Shen, X. Tong, Qing Chen, 2010, Bioorganic & medicinal chemistry letters.