Ruihong Wang

发表

BRCA1, Histone H2AX Phosphorylation, and Male Meiotic Sex Chromosome Inactivation

C. Deng, Sangsoo Kim, J. Barrett, 2004, Current Biology.

Prothymosin α in Vivo Contains Phosphorylated Glutamic Acid Residues*

S. L. Berger, S. Enkemann, M. Trumbore, 1997, The Journal of Biological Chemistry.

A Role of Smad4 in Iron Metabolism through the Positive Regulation of Hepcidin Expression

Xiaoling Xu, C. Deng, L. Mishra, 2022 .

SIRT1 Deacetylates TopBP1 and Modulates Intra-S-Phase Checkpoint and DNA Replication Origin Firing

Y. Pommier, C. Deng, E. Appella, 2014, International journal of biological sciences.

Progression of Chronic Liver Inflammation and Fibrosis Driven by Activation of c-JUN Signaling in Sirt6 Mutant Mice*

C. Deng, H. Young, T. Lahusen, 2012, The Journal of Biological Chemistry.

Inhibitory Phosphorylation of PP1α Catalytic Subunit during the G1/S Transition*

A. Schönthal, E. Villa-Moruzzi, N. Berndt, 1999, The Journal of Biological Chemistry.

Impaired skin and mammary gland development and increased gamma-irradiation-induced tumorigenesis in mice carrying a mutation of S1152-ATM phosphorylation site in Brca1.

C. Deng, Liu Cao, Sung-Chul Lim, 2009, Cancer research.

The Inhibition and Treatment of Breast Cancer with Poly (ADP-ribose) Polymerase (PARP-1) Inhibitors

C. Deng, S. Prindiville, Liu Cao, 2006, International journal of biological sciences.

Inducible suppression of Fgfr2 and Survivin in ES cells using a combination of the RNA interference (RNAi) and the Cre-LoxP system.

X. Coumoul, Wenmei Li, C. Deng, 2004, Nucleic acids research.

Genetic Interactions between Brca1 and Gadd45a in Centrosome Duplication, Genetic Stability, and Neural Tube Closure*

C. Deng, A. Fornace, M. C. Hollander, 2004, Journal of Biological Chemistry.

The new portrait of mammary gland stem cells

Ruihong Wang, 2006, International journal of biological sciences.

SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion

C. Deng, Wenhui Hao, Xiaoling Xu, 2017, Cell reports.

Protein phosphatase 1α-mediated stimulation of apoptosis is associated with dephosphorylation of the retinoblastoma protein

N. Berndt, C. Liu, V. Avramis, 2001, Oncogene.

Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection

Yueqin Liu, Wenli Liu, Cuiling Li, 2010, Proceedings of the National Academy of Sciences.

Smad7, Id1, and Atoh8 in the mouse liver Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6,

J. Mosser, A. Monnier, S. Vaulont, 2013 .

Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.

Yueqin Liu, Wenli Liu, G. Rodgers, 2010, Blood.

Adapted Resistance to the Knockdown Effect of shRNA-Derived Srsf3 siRNAs in Mouse Littermates

C. Deng, R. Jia, Zhi-Ming Zheng, 2015, International journal of biological sciences.

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint.

C. Deng, Hongtao Yu, Ruihong Wang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Metabolic regulation of protein‐bound glutamyl phosphates: Insights into the function of prothymosin α

S. L. Berger, S. Enkemann, M. Trumbore, 1999, Journal of cellular physiology.

Associations among Metabolism, Circadian Rhythm and Age-Associated Diseases

Ruihong Wang, Yiwei Cao, Ruihong Wang, 2017, Aging and disease.

BRCA1 affects global DNA methylation through regulation of DNMT1

X. Coumoul, Mutsuko Ouchi, C. Deng, 2010, Cell Research.

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver.

Jean Mosser, J. Mosser, A. Monnier, 2008, Blood.

Functional discontinuities in prothymosin α caused by caspase cleavage in apoptotic cells

S. L. Berger, S. Enkemann, M. Trumbore, 2000, Journal of cellular physiology.

Turnover of the Acyl Phosphates of Human and Murine Prothymosin α in Vivo *

L Tao, S. L. Berger, M. Trumbore, 1997, The Journal of Biological Chemistry.

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

S. Goh, Y. T. Lee, Jeffery L. Miller, 2007, Nature Medicine.

SIRT1 Deacetylates FOXA2 and Is Critical for Pdx1 Transcription and β-Cell Formation

C. Deng, Zhen Xiao, Hyun-Seok Kim, 2013, International journal of biological sciences.

Murine Wee1 Plays a Critical Role in Cell Cycle Regulation and Pre-Implantation Stages of Embryonic Development

C. Deng, Cuiling Li, Ruihong Wang, 2006, International journal of biological sciences.

Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference

X. Coumoul, C. Deng, Cuiling Li, 2005, Nucleic acids research.

SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism.

Xiaoling Xu, Seung Min Jeong, Clary B Clish, 2013, Cancer cell.

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.

C. Deng, K. Gardner, M. Hung, 2008, Molecular cell.

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice.

G. Gores, C. Deng, M. Torbenson, 2006, The Journal of clinical investigation.

Roles of BRCA1 in DNA damage repair: a link between development and cancer.

C. Deng, Ruihong Wang, Ruihong Wang, 2003, Human molecular genetics.

Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging

Kairong Cui, K. Zhao, C. Deng, 2016, Scientific Reports.

A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.

C. Deng, A. Nussenzweig, Junjie Chen, 2009, Molecular cell.

Absence of the full-length breast cancer-associated gene-1 leads to increased expression of insulin-like growth factor signaling axis members.

X. Coumoul, S. Andò, D. Leroith, 2006, Cancer research.

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

C. Deng, M. Greene, C. Isaacs, 2011, Nature Medicine.

SIRT1 deficiency compromises mouse embryonic stem cell differentiation, and embryonic and adult hematopoiesis in the mouse

C. Deng, H. Broxmeyer, H. Chae, 2012 .

ATM – Chk 2 – p 53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca 1 deficiency

Noboru, Motoyama, X. Coumoul, 2013 .

ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency

S. Elledge, X. Coumoul, C. Deng, 2006, The EMBO journal.

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.

C. Deng, O. Gavrilova, Hyun-Seok Kim, 2011, The Journal of clinical investigation.

Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis.

Xiaoling Xu, Won-Il Jeong, Bin Gao, 2010, Cell metabolism.

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity.

X. Wang, T. Veenstra, C. Deng, 2011, Cancer cell.

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.

X. Wang, C. Deng, E. Appella, 2008, Cancer cell.

SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice*

Oksana Gavrilova, William Jou, Xiaoling Xu, 2010, The Journal of Biological Chemistry.

Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors

C. Deng, E. Choi, Jeong-A Lim, 2018, Experimental & Molecular Medicine.

Identification and characterization of cancer initiating cells from BRCA1 related mammary tumors using markers for normal mammary stem cells

C. Deng, R. Koup, D. Ambrozak, 2008, International journal of biological sciences.

RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis

X. Coumoul, C. Deng, Hyun-Seok Kim, 2007, Nature Genetics.

Erratum: Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

C. Deng, M. Greene, C. Isaacs, 2011, Nature Medicine.

Protein phosphatase 1α activity prevents oncogenic transformation

N. Berndt, Rui-Hong Wang, Norbert Berndt, 2006 .

Liver Steatosis and Increased ChREBP Expression in Mice Carrying a Liver Specific SIRT1 Null Mutation under a Normal Feeding Condition

C. Deng, Cuiling Li, Ruihong Wang, 2010, International journal of biological sciences.

Efficient drug screening and gene correction for treating liver disease using patient‐specific stem cells

Yoon-Young Jang, Jun O. Liu, S. Leach, 2013, Hepatology.

Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR*

F. Liu, W. Ogawa, Lijun Zhou, 2010, The Journal of Biological Chemistry.

SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse.

C. Deng, H. Broxmeyer, H. Chae, 2011, Blood.

Sirt1, Notch and stem cell "age asymmetry"

H. Broxmeyer, C. Mantel, C. Deng, 2008, Cell cycle.

Hyperplasia and Spontaneous Tumor Development in the Gynecologic System in Mice Lacking the BRCA1-Δ11 Isoform

C. Deng, Liu Cao, Sung-Chul Lim, 2006, Molecular and Cellular Biology.

Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice

C. Deng, D. Schrump, Xiaoling Xu, 2021, Oncogene.

Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach.

X. Coumoul, C. Deng, Xiaoling Xu, 2007, Carcinogenesis.

Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo.

C. Deng, C. Brocker, F. Gonzalez, 2014, American journal of physiology. Endocrinology and metabolism.

The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment

C. Deng, M. Chua, Y. Chinn, 2020, EBioMedicine.

Olfactomedin 4 Is Essential for Superoxide Production and Sensitizes Oxidative Stress-Induced Apoptosis in Neutrophils.

C. Deng, Yueqin Liu, Wenli Liu, 2009 .

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression.

C. Deng, L. Mishra, Xiaoling Xu, 2005, Cell metabolism.