S. Kwak

Y. Kawahara, S. Kwak, 2005, Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases.

Human spinal motoneurons express low relative abundance of GluR2 mRNA: an implication for excitotoxicity in ALS

I. Kanazawa, Y. Kawahara, S. Kwak, 2003, Journal of neurochemistry.

Concentration-dependent changes in motor behavior produced by continuous intrathecal infusion of excitatory amino acids in the rat spinal cord.

S. Kwak, A. Hirata, R. Nakamura, 1997, Brain research. Brain research protocols.

Acute and late neurotoxicity in the rat spinal cord in vivo induced by glutamate receptor agonists

S. Kwak, Ryoji Nakamura, 1995, Journal of the Neurological Sciences.

High‐affinity Na+/K+‐dependent glutamate transporter EAAT4 is expressed throughout the rat fore‐ and midbrain

L. Arckens, Y. Michotte, R. Mccullumsmith, 2008, The Journal of comparative neurology.

Aceruloplasminemia in a Japanese woman with a novel mutation of CP gene: Clinical presentations and analysis of genetic and molecular pathogenesis

A. Hida, S. Tsuji, A. Iwata, 2010, Journal of the Neurological Sciences.

Evaluation of corticospinal tracts in ALS with diffusion tensor MRI and brainstem stimulation

I. Kanazawa, O. Abe, S. Aoki, 2008, Neurology.

Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons

S. Tsuji, A. Kakita, Hitoshi Takahashi, 2012, Neurobiology of Disease.

Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in an ALS mouse model

S. Kwak, T. Yamashita, S. Teramoto, 2022, Life Science Alliance.

4 – Use of Acromelic Acid for Production of Rat Spinal Lesions

H. Shinozaki, S. Kwak, M. Ishida, 1991 .

Determination of editors at the novel A-to-I editing positions

S. Tsuji, N. Suzuki, Y. Nishimoto, 2008, Neuroscience Research.

Studies on neurotransmitter markers and neuronal cell density in the cerebellar system in olivopontocerebellar atrophy and cortical cerebellar atrophy

I. Kanazawa, N. Nukina, H. Mizusawa, 1985, Journal of the Neurological Sciences.

Cell death cascade and molecular therapy in ADAR2-deficient motor neurons of ALS

S. Kwak, T. Yamashita, 2019, Neuroscience Research.

A case of adult onset pure pallidal degeneration I. Clinical manifestations and neuropathological observations

H. Shibasaki, J. Goto, I. Nakano, 1991, Journal of the Neurological Sciences.

Cancer association as a risk factor for anti-HMGCR antibody-positive myopathy

A. Hida, S. Tsuji, M. Inoue, 2016, Neurology: Neuroimmunology & Neuroinflammation.

A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology

T. Saido, N. Iwata, S. Kwak, 2012, Nature Communications.

AMPA receptor‐mediated neuronal death in sporadic ALS

S. Kwak, T. Hideyama, H. Aizawa, 2010, Neuropathology : official journal of the Japanese Society of Neuropathology.

Altered Intracellular Milieu of ADAR2-Deficient Motor Neurons in Amyotrophic Lateral Sclerosis

S. Kwak, Takenari Yamashita, Shin Kwak, 2017, Genes.

Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line

N. Hasebe, J. Sawada, S. Kwak, 2009, Neuroscience Research.

Newly identified ADAR-mediated A-to-I editing positions as a tool for ALS research

Y. Nishimoto, S. Kwak, T. Yamashita, 2008, RNA biology.

In situ nick end-labeling detects necrosis of hippocampal pyramidal cells induced by kainic acid

I. Kanazawa, S. Takekoshi, Keiichi Watanabe, 1996, Neuroscience Letters.

Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2

P. Seeburg, S. Tsuji, M. Higuchi, 2010, The Journal of Neuroscience.

Roles of Aging, Circular RNAs, and RNA Editing in the Pathogenesis of Amyotrophic Lateral Sclerosis: Potential Biomarkers and Therapeutic Targets

S. Kwak, H. Tsuji, Takashi Hosaka, 2023, Cells.

A case of adult onset pure pallidal degeneration II. Analysis of neurotransmitter markers, with special reference to the termination of pallidothalamic tract in human brain

H. Shibasaki, T. Mannen, S. Kwak, 1991, Journal of the Neurological Sciences.

ADAR2-dependent A-to-I RNA editing in the extracellular linear and circular RNAs

A. Tamaoka, T. Hosaka, S. Kwak, 2019, Neuroscience Research.

The AMPA receptor antagonist perampanel robustly rescues amyotrophic lateral sclerosis (ALS) pathology in sporadic ALS model mice

S. Kwak, T. Yamashita, S. Teramoto, 2016, Scientific Reports.

Co-Occurrence of TDP-43 Mislocalization with Reduced Activity of an RNA Editing Enzyme, ADAR2, in Aged Mouse Motor Neurons

S. Kwak, T. Hideyama, T. Yamashita, 2012, PloS one.

Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA

S. Tsuji, G. Sobue, Y. Kawahara, 2006, Neuroscience Research.

Increased Cu/Zn superoxide dismutase-like immunoreactivity in the swollen axons of rats intoxicated chronically with β,β′-iminodipropionitrile

Masahiko Watanabe, I. Kanazawa, S. Murayama, 1995, Neuroscience Letters.

GluR4c, an alternative splicing isoform of GluR4, is abundantly expressed in the adult human brain.

I. Kanazawa, Y. Kawahara, S. Kwak, 2004, Brain research. Molecular brain research.

Edited GluR2, a gatekeeper for motor neurone survival?

S. Buckingham, A. Jones, S. Blackshaw, 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

The abnormal processing of TDP-43 is not an upstream event of reduced ADAR2 activity in ALS motor neurons

S. Kwak, T. Hideyama, T. Yamashita, 2012, Neuroscience Research.

Studies on neurotransmitter markers of the basal ganglia in Pick's disease, with special reference to dopamine reduction

I. Kanazawa, T. Mizutani, N. Nukina, 1988, Journal of the Neurological Sciences.

Small neurons in the lower spinal cord are selectively damaged in the spastic rat by acromelic acid

H. Shinozaki, S. Kwak, H. Aizawa, 1990 .

Agonists for metabotropic glutamate receptors in the rat delay recovery from halothane anesthesia.

H. Shinozaki, S. Kwak, M. Ishida, 1994, European journal of pharmacology.

Tridimensional distribution of markers of neurotransmitters within the “accumbens area” of normal human brains

I. Kanazawa, Y. Toyokura, H. Sugita, 1984, Neuroscience.

Novel splice variants of human ADAR2 mRNA: skipping of the exon encoding the dsRNA-binding domains, and multiple C-terminal splice sites.

S. Tsuji, Y. Kawahara, S. Kwak, 2005, Gene.

Specific lesions of rat spinal interneurons induced by systemic administration of acromelic acid, a new potent kainate analogue

H. Shinozaki, S. Kwak, M. Ishida, 1989, Brain Research.

Pharmacological Contradictions in Neurotoxicity of Excitatory Amino Acids as a Cause of Ischemic Injuries

H. Shinozaki, S. Kwak, M. Ishida, 1992 .

Acromelic acid as a tool for the study of specific neurone damages

H. Shinozaki, S. Kwak, M. Ishida, 1990 .

Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptor‐mediated excitotoxicity in ALS

I. Kanazawa, Y. Kawahara, S. Kwak, 2006, Journal of neurochemistry.

Prolyl Isomerase Pin1 Expression in the Spinal Motor Neurons of Patients With Sporadic Amyotrophic Lateral Sclerosis

S. Kwak, T. Hideyama, H. Aizawa, 2022, Journal of clinical neurology.

Effect of Serum Perampanel Concentration on Sporadic Amyotrophic Lateral Sclerosis Progression

S. Kwak, T. Hideyama, H. Aizawa, 2023, Journal of clinical neurology.

Noise-induced compensation for postural hypotension in primary autonomic failure

Yoshiharu Yamamoto, I. Hidaka, R. Soma, 2002, Brain Research.

The AMPA receptor antagonist perampanel robustly rescues amyotrophic lateral sclerosis (ALS) pathology in sporadic ALS model mice

S. Kwak, T. Yamashita, S. Teramoto, 2016, Scientific Reports.

Ethanol Preference and Drinking Behavior Are Controlled by RNA Editing in the Nucleus Accumbens

Yoshihisa Watanabe, Masaki Tanaka, S. Kwak, 2019, Front. Behav. Neurosci..

Genetic and epigenetic studies of amyotrophic lateral sclerosis

A. Al-Chalabi, T. Siddique, P. Leigh, 2013, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Unique nuclear vacuoles in the motor neurons of conditional ADAR2-knockout mice

S. Kwak, S. Sasaki, T. Hideyama, 2014, Brain Research.

High‐affinity Na+/K+‐dependent glutamate transporter EAAT4 is expressed throughout the rat fore‐ and midbrain

L. Arckens, Y. Michotte, R. Mccullumsmith, 2008, The Journal of comparative neurology.

Denervation induces long-lasting changes in the distribution of microtubule proteins in hippocampal neurons

A. Matus, S. Kwak, S. Kwak, 1988, Journal of Neurocytology.

Systemic administration of acromelic acid induces selective neuron damage in the rat spinal cord.

H. Shinozaki, S. Kwak, H. Aizawa, 1991, Life sciences.

Ca2+‐permeable AMPA receptors associated with epileptogenesis of hypothalamic hamartoma

H. Kitaura, A. Kakita, S. Kameyama, 2017, Epilepsia.

Hemiparkinsonism associated with a mesencephalic tumor

I. Kanazawa, T. Momose, I. Imafuku, 2002, Journal of the Neurological Sciences.