H. Marriott

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Decreased Alveolar Macrophage Apoptosis Is Associated with Increased Pulmonary Inflammation in a Murine Model of Pneumococcal Pneumonia1

S. Cross, P. Ince, H. Marriott, 2006, The Journal of Immunology.

Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

S. Cross, R. Chambers, N. Arnold, 2012, Thorax.

Polymersomes Eradicating Intracellular Bacteria.

S. Foster, A. Poma, L. Rizzello, 2020, ACS nano.

HIV gp120 in the Lungs of Antiretroviral Therapy‐treated Individuals Impairs Alveolar Macrophage Responses to Pneumococci

M. Noursadeghi, R. Read, A. Geretti, 2018, American journal of respiratory and critical care medicine.

A mathematical model shows macrophages delay Staphylococcus aureus replication, but limitations in microbicidal capacity restrict bacterial clearance

M. Boots, H. Marriott, D. Dockrell, 2020, Journal of theoretical biology.

Divergent Roles for TRAIL in Lung Diseases

A. Lawrie, H. Marriott, A. Braithwaite, 2018, Front. Med..

A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia

D. Witcher, V. Wroblewski, S. Walmsley, 2012, Thorax.

Interleukin-1β Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages

T. Mitchell, G. Pozzi, M. Nicklin, 2011, Infection and Immunity.

Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y11 Receptor1

A. Surprenant, C. Bingle, M. Kassack, 2007, The Journal of Immunology.

Inhaled Nitric Oxide as a Therapy for Diseases of the Pulmonary Vasculature

T. Higenbottam, H. Marriott, 2000 .

The acute effects of dexfenfluramine on human and porcine pulmonary vascular tone and resistance.

T. Higenbottam, E. Laude, H. Marriott, 1999, Chest.

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.

P. Carmeliet, P. Ratcliffe, C. Taylor, 2011, The Journal of clinical investigation.

Evaluation of the anti-inflammatory effects of β-adrenoceptor agonists on human lung macrophages.

H. Marriott, S. Suvarna, P. Peachell, 2016, European journal of pharmacology.

Phd 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

P. Carmeliet, P. Ratcliffe, C. Taylor, 2017 .

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

P. Carmeliet, P. Ratcliffe, C. Taylor, 2017, The Journal of clinical investigation.

Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.

F. Formenti, F. V. van Eeden, P. Robbins, 2014, Blood.

PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Hypoxia-inducible factor 2 a regulates key neutrophil functions in humans , mice , and zebra fi sh

F. Formenti, P. Robbins, R. Johnson, 2014 .

A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci

G. Kroemer, B. Chain, T. Mitchell, 2011, PLoS pathogens.

Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages

S. Foster, R. Read, S. Johnston, 2015, Cellular microbiology.

Polymersomes Targeting Mononuclear Phagocytes

S. Foster, S. Yona, A. Poma, 2017 .

Targeting mononuclear phagocytes for eradicating intracellular parasites

S. Foster, S. Yona, A. Poma, 2017, bioRxiv.

Model of Pulmonary Infection to Pneumococcal Clearance in a Resolving Alveolar Macrophage Apoptosis Contributes

P. Ince, V. Ridger, H. Marriott, 2003 .

Pneumolysin: a double-edged sword during the host-pathogen interaction.

T. Mitchell, H. Marriott, D. Dockrell, 2008, Current molecular medicine.

Pneumolysin Activates Macrophage Lysosomal Membrane Permeabilization and Executes Apoptosis by Distinct Mechanisms without Membrane Pore Formation

T. Mitchell, R. Read, Ashleigh Holmes, 2014, mBio.

Distinct Mechanisms without Membrane Pore Formation Membrane Permeabilization and Executes Apoptosis by Pneumolysin Activates Macrophage Lysosomal 2014

T. Mitchell, R. Read, Ashleigh Holmes, 2014 .

Streptococcus pneumoniae: the role of apoptosis in host defense and pathogenesis.

H. Marriott, D. Dockrell, 2006, The international journal of biochemistry & cell biology.

THE ROLE OF THE MACROPHAGE IN LUNG DISEASE MEDIATED BY BACTERIA

H. Marriott, D. Dockrell, 2007, Experimental lung research.

Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia.

S. Cross, D. Greaves, S. Shapiro, 2019, American journal of respiratory and critical care medicine.

The anti‐inflammatory effects of PGE2 on human lung macrophages are mediated by the EP4 receptor

H. Marriott, L. Kay, P. Peachell, 2016, British journal of pharmacology.

Pellino-1 Regulates the Responses of the Airway to Viral Infection

J. Stewart, Shao-Cong Sun, W. Timens, 2018, Frontiers in Cellular and Infection Microbiology.

Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages

Dave Singh, D. Greaves, C. Brightling, 2017, American journal of respiratory and critical care medicine.

Liposomal Co-Entrapment of CD40mAb Induces Enhanced IgG Responses against Bacterial Polysaccharide and Protein

A. Heath, H. Marriott, C. Hatzifoti, 2008, PloS one.

Mitochondrial fission is increased in macrophages during mROS production in response to S. pneumoniae

P. Bullough, P. Shaw, K. D. De Vos, 2021, bioRxiv.

Macrophages utilize mitochondrial fission to enhance mROS production during responses to Streptococcus pneumoniae

P. Bullough, P. Shaw, K. D. De Vos, 2019 .

Contrasting roles for reactive oxygen species and nitric oxide in the innate response to pulmonary infection with Streptococcus pneumoniae.

H. Marriott, P. Hellewell, M. Whyte, 2007, Vaccine.

Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection

T. J. Mitchell, R. Read, H. Marriott, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Deﬁciency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and ﬁbrosis

R. Chambers, N. Arnold, S. Walmsley, 2022 .

Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa.

G. Taylor, P. Henson, H. Marriott, 2008, American journal of respiratory and critical care medicine.

Bacterial Disease Challenge with Common Causes of Invasive Regulate Innate Responses Following Distinct Cell Death Programs in Monocytes

C. Read, S. Walmsley, A. Preston, 2010 .

Pneumococcal Pneumonia Inflammation in a Murine Model of Associated with Increased Pulmonary Decreased Alveolar Macrophage Apoptosis Is

S. Cross, H. Marriott, P. Hellewell, 2006 .

Interleukin-1 (cid:1) Regulates CXCL8 Release and Inﬂuences Disease Outcome in Response to Streptococcus pneumoniae , Deﬁning Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages

T. Mitchell, G. Pozzi, M. Nicklin, 2022 .

Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia.

T. S. Wilkinson, S. Cross, P. Ince, 2008, American journal of respiratory and critical care medicine.

Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin1

G. Taylor, S. Walmsley, D. Buttle, 2008, The Journal of Immunology.

Bacterial Toxin , Pyocyanin Regulating Neutrophil Apoptosis by a Major Subversion of a Lysosomal Pathway Dockrell and

G. Taylor, S. Walmsley, D. Buttle, 2008 .

Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism

P. Carmeliet, S. Foster, J. Thomson, 2017, Science Immunology.

HIV gp120 in Lungs of ART-‐Treated Individuals Impairs Alveolar Macrophage 2 Responses To Pneumococci 3

M. Noursadeghi, R. Read, A. Geretti, 2018 .

Inhibition of Macrophage Apoptosis by Neisseria meningitidis Requires Nitric Oxide Detoxification Mechanisms

R. Read, H. Marriott, D. Dockrell, 2006, Infection and Immunity.

The mouse lung early cellular innate immune response is not sufficient to control fungal infection with Cryptococcus neoformans

L. Carlin, S. Johnston, H. Marriott, 2019, bioRxiv.

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

Marc Daigneault, David H. Dockrell, Moira K. B. Whyte, 2010, PloS one.

RIPOSTE: a framework for improving the design and analysis of laboratory-based research

James M. Eales, Bethany Shinkins, M Dawn Teare, 2015, eLife.

Alveolar macrophages in pulmonary host defence – the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing

H. Marriott, D. Dockrell, M. Bewley, 2013, Clinical and experimental immunology.

Monocytes Regulate the Mechanism of T-cell Death by Inducing Fas-Mediated Apoptosis during Bacterial Infection

T. Mitchell, R. Read, T. D. de Silva, 2012, PLoS pathogens.

The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages

M. Collins, S. Renshaw, H. Marriott, 2022, bioRxiv.

Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance.

G. Kroemer, R. Craig, R. Read, 2005, The Journal of clinical investigation.

Alveolar Macrophage Apoptosis Contributes to Pneumococcal Clearance in a Resolving Model of Pulmonary Infection 1

P. Ince, V. Ridger, H. Marriott, 2003, The Journal of Immunology.

Proteomic Evaluation and Validation of Cathepsin D Regulated Proteins in Macrophages Exposed to Streptococcus pneumoniae*

P. Wright, B. Chain, J. Noirel, 2011, Molecular & Cellular Proteomics.

S. Francis, S. Renshaw, A. Lawrie, 2011, Journal of leukocyte biology.

Mechanistic links between acute respiratory tract infections and acute coronary syndromes.

S. Francis, H. Marriott, D. Dockrell, 2013, The Journal of infection.

Transient increase in atherosclerotic plaque macrophage content following Streptococcus pneumoniae pneumonia in ApoE-deficient mice

P. Heath, S. Francis, C. Gelsthorpe, 2022, Frontiers in Cellular and Infection Microbiology.

Distinct Cell Death Programs in Monocytes Regulate Innate Responses Following Challenge with Common Causes of Invasive Bacterial Disease

S. Walmsley, R. Read, H. Marriott, 2010, The Journal of Immunology.

Primary and secondary pulmonary hypertension

T. Higenbottam, H. Marriott, T. Siddons, 1998 .

Circulating nitrite anions are a directly acting vasodilator and are donors for nitric oxide.

M. B. Davies, T. Higenbottam, P. J. Foster, 2002, Clinical science.

Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice

L. Bingle, C. Bingle, E. E. LeClair, 2012, Cell and Tissue Research.

Pellino-1 Regulates Immune Responses to Haemophilus influenzae in Models of Inflammatory Lung Disease

Shao-Cong Sun, A. Condliffe, H. Marriott, 2019, Front. Immunol..

Alveolar macrophages in pulmonary host defence – the unrecognized role of apoptosis as a mechanism of intracellular bacterial killing

H. Marriott, D. Dockrell, J. Aberdein, 2013, Clinical and experimental immunology.

Edinburgh Research Explorer TNF-related apoptosis-inducing ligand (TRAIL) regulates inflammatory neutrophil apoptosis and enhances resolution of inflammation

S. Renshaw, A. Lawrie, H. Marriott, 2022 .