C. Höbartner

发表

V. Peña, A. Ponce-Salvatierra, Katarzyna Wawrzyniak-Turek, 2016, Nature.

Machine learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes

R. Micura, A. Hildebrandt, M. Helm, 2020, Nucleic acids research.

Preparation of 2′‐Deoxy‐2′‐Methylseleno‐Modified Phosphoramidites and RNA

R. Micura, Kathrin Lang, Renate Rieder, 2006, Current protocols in nucleic acid chemistry.

Chemical synthesis of selenium-modified oligoribonucleotides and their enzymatic ligation leading to an U6 SnRNA stem-loop segment.

R. Micura, C. Höbartner, 2004, Journal of the American Chemical Society.

Bistable secondary structures of small RNAs and their structural probing by comparative imino proton NMR spectroscopy.

R. Micura, Ronald Micura, C. Höbartner, 2003, Journal of molecular biology.

1 Chemical Synthesis of Modified RNA

C. Höbartner, Falk Wachowius, F. Wachowius, 2010 .

Chemical Synthesis of Modified RNA

C. Höbartner, Falk Wachowius, F. Wachowius, 2010 .

Chemical RNA Modifications for Studies of RNA Structure and Dynamics

C. Höbartner, Falk Wachowius, 2010, Chembiochem : a European journal of chemical biology.

On Secondary Structure Rearrangements and Equilibria of Small RNAs

R. Micura, C. Höbartner, 2003, Chembiochem : a European journal of chemical biology.

Fundamental studies of functional nucleic acids: aptamers, riboswitches, ribozymes and DNAzymes.

R. Micura, C. Höbartner, 2020, Chemical Society reviews.

Nucleic Acid‐Catalyzed RNA Ligation and Labeling

C. Höbartner, M. Maghami, 2021, Ribozymes.

Combinatorial mutation interference analysis reveals functional nucleotides required for DNA catalysis.

C. Höbartner, F. Javadi-Zarnaghi, Falk Wachowius, 2010, Angewandte Chemie.

RNA-Cleaving DNA Enzymes and Their Potential Therapeutic Applications as Antibacterial and Antiviral Agents

P. I. Pradeepkumar, C. Höbartner, P. Pradeepkumar, 2012, From Nucleic Acids Sequences to Molecular Medicine.

Aptamers provide superior stainings of cellular receptors studied under super-resolution microscopy

C. Höbartner, M. A. Gomes de Castro, F. Opazo, 2017, PloS one.

High-Throughput Activity Profiling of RNA-Cleaving DNA Catalysts by Deoxyribozyme Sequencing (DZ-seq).

C. Höbartner, M. Sednev, A. Liaqat, 2022, Journal of the American Chemical Society.

On Secondary Structure Rearrangements and Equilibria of Small RNAs

R. Micura, C. Höbartner, 2003, Chembiochem : a European journal of chemical biology.

Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis

C. Dienemann, P. Cramer, J. Schmitzová, 2021, Nature Structural & Molecular Biology.

Mechanism of SARS-CoV-2 polymerase inhibition by remdesivir

D. Tegunov, C. Dienemann, P. Cramer, 2020, bioRxiv.

Eukaryotic 5-methylcytosine (m5C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease

M. Bohnsack, C. Höbartner, K. Bohnsack, 2019, Genes.

Structure and mechanism of the methyltransferase ribozyme MTR1

H. Schindelin, C. Höbartner, M. Mieczkowski, 2022, Nature Chemical Biology.

Debranchase-resistant labeling of RNA using the 10DM24 deoxyribozyme and fluorescent modified nucleotides.

A. Hoskins, C. Höbartner, T. Carrocci, 2017, Chemical communications.

Chemical RNA Modifications for Studies of RNA Structure and Dynamics

C. Höbartner, Falk Wachowius, F. Wachowius, 2010, Chembiochem : a European journal of chemical biology.

One pot synthesis of Cu(II) 2,2'-bipyridyl complexes of 5-hydroxy-hydurilic acid and alloxanic acid: synthesis, crystal structure, chemical nuclease activity and cytotoxicity.

S. K. Trigun, R. Koiri, C. Höbartner, 2011, Journal of inorganic biochemistry.

Synthesis and characterization of RNA containing a rigid and nonperturbing cytidine-derived spin label.

S. Sigurdsson, C. Höbartner, Falk Wachowius, 2012, The Journal of organic chemistry.

Measurement of Angstrom to Nanometer Molecular Distances with 19 F Nuclear Spins by EPR/ENDOR Spectroscopy

M. Bennati, C. Höbartner, S. Dechert, 2019, Angewandte Chemie.

High-resolution measurement of long-range distances in RNA: pulse EPR spectroscopy with TEMPO-labeled nucleotides† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc04631a

M. Bennati, Deniz Sezer, C. Höbartner, 2016, Chemical science.

Synthesis and properties of DNA oligonucleotides with a zwitterionic backbone structure.

Anatol P. Spork, C. Ducho, C. Höbartner, 2014, Chemical communications.

Biochemie 2011. 5-Hydroxymethylcytosin im Genom

C. Höbartner, 2012 .

Enzymatische Derivatisierung von 5‐Hydroxymethylcytosin in DNA

C. Höbartner, 2011 .

Enzymatic labeling of 5-hydroxymethylcytosine in DNA.

C. Höbartner, 2011, Angewandte Chemie.

Large Stokes shift fluorescence activation in an RNA aptamer by intermolecular proton transfer to guanine

C. Lambert, V. Peña, C. Höbartner, 2021, Nature Communications.

Structure–fluorescence activation relationships of a large Stokes shift fluorogenic RNA aptamer

C. Höbartner, Irene Bessi, C. Steinmetzger, 2019, Nucleic acids research.

Repurposing Antiviral Drugs for Orthogonal RNA‐Catalyzed Labeling of RNA

C. Höbartner, Surjendu Dey, Ann‐Kathrin Lenz, 2020, Angewandte Chemie.

N6‐Isopentenyladenosine in RNA Determines the Cleavage Site of Endonuclease Deoxyribozymes

C. Höbartner, M. Sednev, M. Michel, 2020, Angewandte Chemie.

N 6‐Isopentenyladenosine in RNA Determines the Cleavage Site of Endonuclease Deoxyribozymes

C. Höbartner, M. Sednev, M. Michel, 2020, Angewandte Chemie.

Tuning Exciton Coupling of Merocyanine Nucleoside Dimers by RNA, DNA and GNA Double Helix Conformations

F. Würthner, C. Höbartner, D. Bialas, 2021, Angewandte Chemie.

A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.

R. Micura, D. Patel, E. Mairhofer, 2015, Angewandte Chemie.

Recent advances in DNA catalysis.

S. Silverman, C. Höbartner, 2007, Biopolymers.

Mechanism of SARS-CoV-2 polymerase stalling by remdesivir

D. Tegunov, C. Dienemann, P. Cramer, 2021, Nature communications.

NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A–T phosphoramidite building blocks

C. Ducho, C. Höbartner, B. Schmidtgall, 2015, Beilstein journal of organic chemistry.

RNA‐Cleaving Deoxyribozymes Differentiate Methylated Cytidine Isomers in RNA

C. Höbartner, M. Sednev, A. Liaqat, 2021, Angewandte Chemie.

Probing secondary structures of spin-labeled RNA by pulsed EPR spectroscopy.

M. Bennati, C. Höbartner, G. Sicoli, 2010, Angewandte Chemie.

Synthesis of spin-labeled riboswitch RNAs using convertible nucleosides and DNA-catalyzed RNA ligation.

C. Höbartner, Jan Seikowski, K. Wawrzyniak, 2013, Bioorganic & medicinal chemistry.

Mg2+-dependent conformational changes and product release during DNA-catalyzed RNA ligation monitored by Bimane fluorescence

T. Jovin, C. Höbartner, E. Turriani, 2014, Nucleic acids research.

Measurement of Angstrom to Nanometer Molecular Distances with 19F Nuclear Spins by EPR/ENDOR Spectroscopy

M. Bennati, C. Höbartner, S. Dechert, 2019, Angewandte Chemie.

Human METTL16 is a N6‐methyladenosine (m6A) methyltransferase that targets pre‐mRNAs and various non‐coding RNAs

Henning Urlaub, Christof Lenz, C. Lenz, 2017, EMBO reports.

A dual-mode microwave resonator for double electron-electron spin resonance spectroscopy at W-band microwave frequencies.

M. Bennati, C. Höbartner, I. Tkach, 2011, Journal of magnetic resonance.

Supramolecular Fluorescence Resonance Energy Transfer in Nucleobase‐Modified Fluorogenic RNA Aptamers

C. Höbartner, C. Steinmetzger, Carmen Bäuerlein, 2020, Angewandte Chemie.

Methylation of the nucleobases in RNA oligonucleotides mediates duplex-hairpin conversion.

R. Micura, M. Ebert, B. Jaun, 2001, Nucleic acids research.

Synthesis, gene silencing, and molecular modeling studies of 4'-C-aminomethyl-2'-O-methyl modified small interfering RNAs.

V. G. Chittoor, S. Patankar, C. Höbartner, 2012, The Journal of organic chemistry.

Triggering of RNA secondary structures by a functionalized nucleobase.

R. Micura, K. Breuker, C. Höbartner, 2004, Angewandte Chemie.

DNA Catalysts for Synthetic Applications in Biomolecular Chemistry

C. Höbartner, P. Pradeepkumar, 2012 .

NSUN3 and ABH1 modify the wobble position of mt‐tRNA Met to expand codon recognition in mitochondrial translation

M. Rodnina, P. Rehling, M. Bohnsack, 2016, The EMBO journal.

NSUN6 is a human RNA methyltransferase that catalyzes formation of m5C72 in specific tRNAs

M. Bohnsack, Ahmed S. Warda, C. Höbartner, 2015, RNA.

Incorporation of 4'-C-aminomethyl-2'-O-methylthymidine into DNA by thermophilic DNA polymerases.

C. Höbartner, Kiran R. Gore, P. Pradeepkumar, 2012, Chemical communications.

Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography.

A. Serganov, A. Polonskaia, R. Micura, 2005, Journal of the American Chemical Society.

Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation

A. Serganov, A. Polonskaia, L. Malinina, 2005, Nature Structural &Molecular Biology.

High-frequency 263 GHz PELDOR

M. Bennati, C. Höbartner, I. Tkach, 2014 .

The ‘hidden side’ of spin labeled oligonucleotides: Molecular Dynamics study focusing on the EPR-silent components of base pairing

G. Groenhof, C. Höbartner, S. Dantu, 2019, bioRxiv.

Chemoselective labeling and site‐specific mapping of 5‐formylcytosine as a cellular nucleic acid modification

D. Feineis, C. Höbartner, Julia Dietzsch, 2018, FEBS letters.

The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5′–3′ exoribonuclease XRN1

M. Bohnsack, K. Sloan, C. Höbartner, 2018, RNA.

Strategies for Characterization of Enzymatic Nucleic Acids.

C. Höbartner, F. Javadi-Zarnaghi, 2017, Advances in biochemical engineering/biotechnology.

The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome

R. Lührmann, J. Schmitzová, P. Fabrizio, 2015, Genes & development.

Efficiency and precision of microRNA biogenesis modes in plants

B. Meyers, J. Palatnik, Rodolfo M. Rasia, 2018, Nucleic acids research.

Fluorogenic Labeling of 5-Formylpyrimidine Nucleotides in DNA and RNA.

C. Höbartner, Jan Seikowski, B. Samanta, 2016, Angewandte Chemie.

Lanthanide cofactors accelerate DNA-catalyzed synthesis of branched RNA.

C. Höbartner, F. Javadi-Zarnaghi, 2013, Journal of the American Chemical Society.

NOseq: amplicon sequencing evaluation method for RNA m6A sites after chemical deamination

J. König, A. Hildebrandt, Jean-Yves Roignant, 2020, Nucleic acids research.

Efficiency and precision of miRNA biogenesis modes in plants

B. Meyers, J. Palatnik, Rodolfo M. Rasia, 2018, bioRxiv.

The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation

Marleen Heinrichs, M. Bohnsack, C. Höbartner, 2022, Nature communications.

Yeast Prp2 liberates the 5′ splice site and the branch site adenosine for catalysis of pre-mRNA splicing

K. Hartmuth, R. Lührmann, C. Höbartner, 2017, RNA.

Substrate-assisted mechanism of RNP disruption by the spliceosomal Brr2 RNA helicase

M. Wahl, C. Höbartner, K. Santos, 2016, Proceedings of the National Academy of Sciences.

N6 -Methyladenosine-Sensitive RNA-Cleaving Deoxyribozymes.

M. Bohnsack, K. Sloan, C. Höbartner, 2018, Angewandte Chemie.

Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions

S. Joseph, E. Westhof, R. Micura, 2018, Nature Communications.

DNA-catalyzed formation of nucleopeptide linkages.

S. Silverman, C. Höbartner, D. A. Baum, 2008, Angewandte Chemie.

Enzymatic combinatorial nucleoside deletion scanning mutagenesis of functional RNA.

Katarzyna Wawrzyniak-Turek, C. Höbartner, 2014, Chemical communications.

Deoxyribozyme-mediated ligation for incorporating EPR spin labels and reporter groups into RNA.

Katarzyna Wawrzyniak-Turek, C. Höbartner, 2014, Methods in enzymology.

Multimodal optical sensing and analyte specificity using single-walled carbon nanotubes.

Michael S Strano, Taekjip Ha, Daniel A Heller, 2009, Nature nanotechnology.

Site-specific RNA methylation by a methyltransferase ribozyme

C. Höbartner, Carolin P. M. Scheitl, Mohammad Ghaem Maghami, 2020, Nature.

Engineering a selective small-molecule substrate binding site into a deoxyribozyme.

S. Silverman, C. Höbartner, 2007, Angewandte Chemie.

Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications.

R. Micura, Renate Rieder, C. Höbartner, 2009, Methods in molecular biology.

Repurposing Antiviral Drugs for Orthogonal RNA‐Catalyzed Labeling of RNA

C. Höbartner, Surjendu Dey, Mohammad Ghaem Maghami, 2020, Angewandte Chemie.

Direct in vitro selection of trans-acting ribozymes for posttranscriptional, site-specific, and covalent fluorescent labeling of RNA.

C. Höbartner, Carolin P. M. Scheitl, Mohammad Ghaem Maghami, 2019, Journal of the American Chemical Society.

Probing essential nucleobase functional groups in aptamers and deoxyribozymes by nucleotide analogue interference mapping of DNA.

C. Höbartner, F. Wachowius, 2011, Journal of the American Chemical Society.

The Synthesis of 2′-O-[(Triisopropylsilyl)oxy] methyl (TOM) Phosphoramidites of Methylated Ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for Use in Automated RNA Solid-Phase Synthesis

R. Micura, C. Kreutz, C. Höbartner, 2003 .

Modulation of RNA tertiary folding by incorporation of caged nucleotides.

S. Silverman, C. Höbartner, 2005, Angewandte Chemie.

RNA Two‐State Conformation Equilibria and the Effect of Nucleobase Methylation

R. Micura, M. Ebert, B. Jaun, 2002 .

Orientation selection in distance measurements between nitroxide spin labels at 94 GHz EPR with variable dual frequency irradiation.

S. Sigurdsson, U. Diederichsen, S. Pornsuwan, 2013, Physical chemistry chemical physics : PCCP.

High-resolution measurement of long-range distances in RNA: pulse EPR spectroscopy with TEMPO-labeled nucleotides

M. Bennati, Deniz Sezer, C. Höbartner, 2016 .

Coronavirus-Replikation: Mechanismus und Inhibition durch Remdesivir

C. Dienemann, P. Cramer, C. Höbartner, 2021, BIOspektrum.

Control of membrane gaps by synaptotagmin-Ca2+ measured with a novel membrane distance ruler

R. Jahn, P. Walla, C. Höbartner, 2014, Nature Communications.

Staining of Membrane Receptors with Fluorescently-labeled DNA Aptamers for Super-resolution Imaging.

C. Höbartner, Maria Angela Gomes de Castro, F. Opazo, 2017, Bio-protocol.

N 6 ‐Methyladenosine‐Sensitive RNA‐Cleaving Deoxyribozymes

M. Bohnsack, K. Sloan, C. Höbartner, 2018, Angewandte Chemie.

Combinatorial nucleoside-deletion-scanning mutagenesis of functional DNA.

C. Höbartner, B. Samanta, 2013, Angewandte Chemie.

Mutationsanalyse funktionaler DNA durch statistische Nucleosiddeletion

C. Höbartner, Biswajit Samanta, 2013 .

In Vitro Assays for RNA Methyltransferase Activity.

M. Bohnsack, K. Sloan, C. Höbartner, 2017, Methods in molecular biology.

Functional Hallmarks of a Catalytic DNA that Makes Lariat RNA.

C. Höbartner, F. Javadi-Zarnaghi, 2016, Chemistry.

Site-selective depurination by a periodate-dependent deoxyribozyme.

S. Silverman, Scott K Silverman, C. Höbartner, 2007, Chemical communications.

A Multicolor Large Stokes Shift Fluorogen-Activating RNA Aptamer with Cationic Chromophores.

C. Höbartner, Kiran R. Gore, C. Steinmetzger, 2019, Chemistry.

Translation of non-standard codon nucleotides reveals minimal requirements for codon-anticodon interactions

S. Joseph, E. Westhof, R. Micura, 2018, Nature Communications.

M. Bennati, Deniz Sezer, C. Höbartner, 2016, Chemical science.

Human METTL16 is a N6‐methyladenosine (m6A) methyltransferase that targets pre‐mRNAs and various non‐coding RNAs

C. Lenz, H. Urlaub, M. Bohnsack, 2017, EMBO reports.

Probing essential nucleobase functional groups in aptamers and deoxyribozymes by nucleotide analogue interference mapping of DNA.

C. Höbartner, F. Wachowius, 2011, Journal of the American Chemical Society.

Combinatorial mutation interference analysis reveals functional nucleotides required for DNA catalysis.

C. Höbartner, F. Javadi-Zarnaghi, F. Wachowius, 2010, Angewandte Chemie.

A Multicolor Large Stokes Shift Fluorogen-Activating RNA Aptamer with Cationic Chromophores.

C. Höbartner, Kiran R. Gore, C. Steinmetzger, 2019, Chemistry.

Eukaryotic 5-methylcytosine (m5C) RNA Methyltransferases: Mechanisms, Cellular Functions, and Links to Disease

M. Bohnsack, C. Höbartner, K. Bohnsack, 2019, Genes.

How RNA modification allows non-conventional decoding in mitochondria

M. Bohnsack, K. Sloan, C. Höbartner, 2017, Cell cycle.

N6 -Methyladenosine-Sensitive RNA-Cleaving Deoxyribozymes.

M. Bohnsack, K. Sloan, C. Höbartner, 2018, Angewandte Chemie.

Synthesis of spin-labeled riboswitch RNAs using convertible nucleosides and DNA-catalyzed RNA ligation.

C. Höbartner, Jan Seikowski, K. Wawrzyniak, 2013, Bioorganic & medicinal chemistry.