V. Wittmann

发表

Visualization of Protein-Specific Glycosylation inside Living Cells.

A. Zumbusch, Waldemar Schrimpf, C. Hauck, 2016, Angewandte Chemie.

Regioselective Cleavage of Thioether Linkages in Microcystin Conjugates.

V. Wittmann, I. Zemskov, H. Kropp, 2016, Chemistry.

Synthetic Glycosphingolipids for Live-Cell Labeling.

M. Dauner, C. Hauck, V. Bachmann, 2016, Bioconjugate chemistry.

Protein Spin Labeling with a Photocaged Nitroxide Using Diels–Alder Chemistry†

M. Drescher, V. Wittmann, Anandi Kugele, 2019, Chembiochem : a European journal of chemical biology.

Exploring the Potential of Norbornene‐Modified Mannosamine Derivatives for Metabolic Glycoengineering

Anne‐Katrin Späte, Verena F. Schart, V. Wittmann, 2016, Chembiochem : a European journal of chemical biology.

Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels-Alder reaction.

A. Marx, R. Winter, V. Wittmann, 2014, Chemical communications.

Terminal alkenes as versatile chemical reporter groups for metabolic oligosaccharide engineering.

Anne‐Katrin Späte, Verena F. Schart, V. Wittmann, 2014, Chemistry.

Two-color glycan labeling of live cells by a combination of Diels-Alder and click chemistry.

W. Reutter, C. Jüngst, Anne‐Katrin Späte, 2013, Angewandte Chemie.

Carbamate-linked lactose: design of clusters and evidence for selectivity to block binding of human lectins to (neo)glycoproteins with increasing degree of branching and to tumor cells.

N. Bovin, H. Gabius, S. André, 2009, Bioconjugate chemistry.

Glycoproteins: Occurrence and Significance

V. Wittmann, 2008 .

Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses

D. Legler, Anne‐Katrin Späte, V. Wittmann, 2016, Journal of leukocyte biology.

Mechanistic Insight into Nanomolar Binding of Multivalent Neoglycopeptides to Wheat Germ Agglutinin.

V. Wittmann, Philipp Rohse, 2016, Chemistry.

Mechanism of multivalent carbohydrate-protein interactions studied by EPR spectroscopy.

M. Drescher, P. Braun, V. Wittmann, 2011, Angewandte Chemie.

S- and C-glycopeptide derivatives of an LH-RH agonist.

H. Kessler, W. König, V. Wittmann, 2009, International journal of peptide and protein research.

Combinatorial Solid-Phase Synthesis of Multivalent Cyclic Neoglycopeptides.

V. Wittmann, Sonja Seeberger, 2000, Angewandte Chemie.

Total Synthesis of Microcystin-LF and Derivatives Thereof.

D. Dietrich, V. Wittmann, I. Zemskov, 2017, The Journal of organic chemistry.

Temporary attachment of carbohydrates to cyclopeptide templates : a new strategy for single-bead analysis of multivalent neoglycopeptides

H. Schägger, V. Wittmann, Sonja Seeberger, 2003 .

Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.

E. Wagner, Ulrich Lächelt, M. Höhn, 2014, Molecular pharmaceutics.

Precipitation-free high-affinity multivalent binding by inline lectin ligands

M. Drescher, V. Wittmann, Philipp Rohse, 2020, Chemical science.

Conformationally Unambiguous Spin Label for Exploring the Binding Site Topology of Multivalent Systems.

W. Myers, M. Drescher, C. Timmel, 2018, The journal of physical chemistry letters.

Structural investigation of multivalent carbohydrate-protein interactions using synthetic biomolecules.

V. Wittmann, 2013, Current opinion in chemical biology.

Spatial Screening of Lectin Ligands : Cyclic Peptides as Scaffolds for Multivalent Presentation of Carbohydrates

V. Wittmann, Sonja Seeberger, 2001 .

Dienophile‐Modified Mannosamine Derivatives for Metabolic Labeling of Sialic Acids: A Comparative Study

Anne‐Katrin Späte, V. Wittmann, Jeremias E. G. A. Dold, 2017, Chembiochem : a European journal of chemical biology.

Rapid labeling of metabolically engineered cell-surface glycoconjugates with a carbamate-linked cyclopropene reporter.

Anne‐Katrin Späte, Verena F. Schart, V. Wittmann, 2014, Bioconjugate chemistry.

Metabolic Glycoengineering with Azide‐ and Alkene‐Modified Hexosamines: Quantification of Sialic Acid Levels

V. Wittmann, Jeremias E. G. A. Dold, Jeremias E. G. A. Dold, 2020, Chembiochem : a European journal of chemical biology.

Cyclopropene derivatives of aminosugars for metabolic glycoengineering

V. Wittmann, Jessica Hassenrück, 2019, Beilstein journal of organic chemistry.

Triple Orthogonal Labeling of Glycans by Applying Photoclick Chemistry

Anne‐Katrin Späte, Verena F. Schart, V. Wittmann, 2019, Chembiochem : a European journal of chemical biology.

Copper(II)-Mediated Activation of Sugar Oxazolines: Mild and Efficient Synthesis of β-Glycosides ofN-Acetylglucosamine

V. Wittmann, D. Lennartz, 2002 .

Short Synthesis of (2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-d-glucopyranosyl)benzene and 4-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-d-glucopyranosyl)bromobenzene

V. Wittmann, C. Fleck, T. Seitz, 2015 .

Human MRP2 exports MC-LR but not the glutathione conjugate.

D. Dietrich, B. Stieger, Gurjot Kaur, 2019, Chemico-biological interactions.

Application of the Inverse-Electron-Demand Diels-Alder Reaction for Metabolic Glycoengineering

V. Wittmann, L. M. Haiber, Markus Kufleitner, 2021, Frontiers in Chemistry.

Application of the Thioacid‐Azide Ligation (TAL) for the Preparation of Glycosylated and Fluorescently Labeled Amino Acids

V. Wittmann, Jamsad Mannuthodikayil, Katja Rohmer, 2015 .

Optimising broadband pulses for DEER depends on concentration and distance range of interest

M. Drescher, V. Wittmann, S. Weickert, 2020, Magnetic Resonance.

Protein Spin Labeling with a Photocaged Nitroxide Using Diels–Alder Chemistry

M. Drescher, V. Wittmann, Anandi Kugele, 2019, Chembiochem : a European journal of chemical biology.

1H-Tetrazole as Catalyst in Phosphomorpholidate Coupling Reactions: Efficient Synthesis of GDP-Fucose, GDP-Mannose, and UDP-Galactose.

Chi‐Huey Wong, V. Wittmann, 1997, The Journal of organic chemistry.

clickECM: Development of a cell-derived extracellular matrix with azide functionalities.

G. Tovar, P. Kluger, S. Keller, 2017, Acta biomaterialia.

Orthogonally Protected Furanoid Sugar Diamino Acids for Solid-Phase Synthesis of Oligosaccharide Mimetics.

V. Wittmann, F. John, 2015, The Journal of organic chemistry.

Generation of an azide-modified extracellular matrix by adipose-derived stem cells using metabolic glycoengineering

P. Kluger, S. Keller, V. Wittmann, 2019, Current Directions in Biomedical Engineering.

Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels–Alder reactions

T. Mayer, Anne‐Katrin Späte, Verena F. Schart, 2014, Beilstein journal of organic chemistry.

Azides in Carbohydrate Chemistry

Henning S. g. Beckmann, V. Wittmann, 2010 .

Synthesis of C-Glycopeptides via Free Radical Addition of Glycosyl Bromides to Dehydroalanine Derivatives†‡

H. Kessler, M. Köck, M. Kottenhahn, 1992 .

Synthese von C-Glycopeptiden durch radikalische Addition von Glycosylbromiden an Dehydroalaninderivate†‡

H. Kessler, M. Köck, M. Kottenhahn, 1992 .

Occurrence and Significance

V. Wittmann, 2001 .

Multivalent Carbohydrate-Functionalized Polymer Nanocrystals.

S. Mecking, V. Wittmann, Q. Tong, 2018, Biomacromolecules.

Rapid Screening of Lectins for Multivalency Effects with a Glycodendrimer Microarray

R. Liskamp, R. Pieters, V. Wittmann, 2010, Chembiochem : a European journal of chemical biology.

Preparation and Transmetallation of a Triphenylstannyl β-D-Glucopyranoside: A highly stereoselective route to β-D-C-glycosides via glycosyl dianions

A. Vasella, H. Kessler, V. Wittmann, 1994 .

De novo sequencing of peptides on single resin beads by MALDI-FTICR tandem mass spectrometry

M. Przybylski, V. Wittmann, A. Semmler, 2010, Journal of the American Society for Mass Spectrometry.

Orthogonally protected sugar diamino acids as building blocks for linear and branched oligosaccharide mimetics.

V. Wittmann, Frank Sicherl, 2005, Angewandte Chemie.

Fluoro-Carba-Sugars are Glycomimetic Activators of the glmS Ribozyme.

G. Mayer, A. Schüller, V. Wittmann, 2017, Chemistry.

Stereoselective synthesis of 1,1'-linked alpha-l-lyxopyranosyl beta-d-glucopyranoside, the proposed biosynthetic precursor of the FG ring system of avilamycins.

V. Wittmann, Magnus S. Schmidt, 2008, Carbohydrate research.

Stereoselective Synthesis of C‐Glycoside with a Glycosyl Dianion

H. Kessler, V. Wittmann, 1993 .

Synthesis and Application of Glycopeptide and Glycoprotein Mimetics

V. Wittmann, Daniel Specker, 2006 .

Structural basis of multivalent binding to wheat germ agglutinin.

K. Diederichs, D. Schwefel, W. Welte, 2010, Journal of the American Chemical Society.

Unexpected formation of complex bridged tetrazoles via intramolecular 1,3-dipolar cycloaddition of 1,2-O-cyanoalkylidene derivatives of 3-azido-3-deoxy-D-allose.

V. Wittmann, M. Worch, 2008, Carbohydrate research.

RNA-Targeting with Aminoglycoside-Analogues

V. Wittmann, 2003 .

Dynamic Combinatorial Libraries

V. Wittmann, 2002 .

Real-Time NMR Studies of Oxyamine Ligations of Reducing Carbohydrates under Equilibrium Conditions.

V. Wittmann, D. E. Wieland, Oliver R. Baudendistel, 2016, Chemistry.

Ligand Recognition by E- and P-Selectin: Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis x Derivatives and Sialyl Lewis x Carboxylic Acids

Chi‐Huey Wong, V. Wittmann, G. Weitz-Schmidt, 1998 .

Synthesis of C‐Glycopeptides via Free Radical Addition of Glycosyl Bromides to Dehydroalanine Derivatives.

H. Kessler, M. Kottenhahn, V. Wittmann, 1992 .

A Tripeptide Approach to the Solid‐Phase Synthesis of Peptide Thioacids and N‐Glycopeptides

C. Unverzagt, V. Wittmann, Odin Keiper, 2019, Chemistry.

Activation of the glmS Ribozyme Confers Bacterial Growth Inhibition

C. Mayer, G. Bierbaum, G. Mayer, 2017, Chembiochem : a European journal of chemical biology.

Carba-sugars activate the glmS-riboswitch of Staphylococcus aureus.

G. Mayer, Christina E Lünse, V. Wittmann, 2011, ACS chemical biology.

Total Syntheses of Callipeltoside A

V. Wittmann, 2002 .

Muropeptide Rescue in Bacillus subtilis Involves Sequential Hydrolysis by β-N-Acetylglucosaminidase and N-Acetylmuramyl-l-Alanine Amidase

C. Mayer, K. Nitzsche, V. Wittmann, 2010, Journal of bacteriology.

Facile Synthesis of Oligosaccharides

V. Wittmann, 2002 .

Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack.

S. Hung, M. Burkart, C. Wong, 1997, Biochemistry.

Structural Comparison of Oligoribonucleotides and Their 2′-Deoxy-2′-fluoro Analogs by heteronuclear NMR spectroscopy

H. Schwalbe, B. Reif, C. Griesinger, 1997 .

Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy.

D. Dietrich, V. Wittmann, Marcia Y Maier, 2018, Chemico-biological interactions.

Machine learning prediction of cyanobacterial toxin (microcystin) toxicodynamics in humans.

F. Schreiber, D. Dietrich, V. Wittmann, 2019, ALTEX.

The STEAP1262–270 peptide encapsulated into PLGA microspheres elicits strong cytotoxic T cell immunity in HLA‐A*0201 transgenic mice—A new approach to immunotherapy against prostate carcinoma

M. Groettrup, D. Legler, V. Wittmann, 2016, The Prostate.

Metabolic glycoengineering - exploring glycosylation with bioorthogonal chemistry.

V. Wittmann, L. M. Haiber, Markus Kufleitner, 2022, Chemical Society reviews.

Time and space-resolved quantification of plasma membrane sialylation for measurements of cell function and neurotoxicity

M. Leist, Anna-Katharina Holzer, Petra Kranaster, 2019, Archives of Toxicology.

An Advanced ‘clickECM’ That Can be Modified by the Inverse‐Electron‐Demand Diels‐Alder Reaction

P. Kluger, V. Wittmann, A. Southan, 2021, Chembiochem : a European journal of chemical biology.

Preparation of carbohydrate arrays by using Diels-Alder reactions with inverse electron demand.

M. Wiessler, Henning S. g. Beckmann, V. Wittmann, 2012, Chemistry.

Bridging lectin binding sites by multivalent carbohydrates.

R. Pieters, V. Wittmann, 2013, Chemical Society reviews.

Efficient N‐Terminal Glycoconjugation of Proteins by the N‐End Rule

N. Budisa, Henning S. g. Beckmann, V. Wittmann, 2008, Chembiochem : a European journal of chemical biology.

Synthesis of Highly Selective Submicromolar Microcystin‐Based Inhibitors of Protein Phosphatase (PP)2A over PP1

B. Simon, F. Salvi, M. Köhn, 2016, Angewandte Chemie.

8 . 2 Glycoproteins : Properties

V. Wittmann, 2010 .

Chapter 8.1 Occurrence and Significance

J. W. Goethe-Universität, V. Wittmann, 2008 .

Chapter 8.2 (Glycoproteins): Properties

J. W. Goethe-Universität, V. Wittmann, 2008 .

One-pot procedure for diazo transfer and azide-alkyne cycloaddition: triazole linkages from amines.

Henning S. g. Beckmann, V. Wittmann, 2007, Organic letters.

Spatial screening of cyclic neoglycopeptides: identification of polyvalent wheat-germ agglutinin ligands.

V. Wittmann, Sonja Seeberger, 2004, Angewandte Chemie.

High-affinity multivalent wheat germ agglutinin ligands by one-pot click reaction

H. Möller, Henning S. g. Beckmann, V. Wittmann, 2012, Beilstein journal of organic chemistry.

NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides.

H. Schwalbe, S. Wijmenga, C. Griesinger, 2004, Angewandte Chemie.

Simultaneous Detection of 14 Microcystin Congeners from Tissue Samples Using UPLC- ESI-MS/MS and Two Different Deuterated Synthetic Microcystins as Internal Standards

D. Dietrich, V. Fessard, V. Wittmann, 2019, Toxins.

N-Acetylmuramyl-L-Alanine Amidase

C. Mayerl, V. Wittmann, Silke Litzinger, 2010 .

Modified Hammerhead Ribozymes as Potential Therapeutics

A. Ganser, M. Grez, J. Engels, 1998 .

Fluoro-Carba-Sugars are Glycomimetic Activators of the glmS Ribozyme.

G. Mayer, A. Schüller, V. Wittmann, 2017, Chemistry.

Intracellular Imaging of Protein-Specific Glycosylation.

A. Zumbusch, Franziska Doll, V. Wittmann, 2018, Methods in enzymology.

Dienophile‐Modified Mannosamine Derivatives for Metabolic Labeling of Sialic Acids: A Comparative Study

Anne‐Katrin Späte, V. Wittmann, Jeremias E. G. A. Dold, 2017, Chembiochem : a European journal of chemical biology.

Terminal alkenes as versatile chemical reporter groups for metabolic oligosaccharide engineering.

Anne‐Katrin Späte, Verena F. Schart, V. Wittmann, 2014, Chemistry.

Identification of d-amino acid oxidase and propiverine interaction partners and their potential role in the propiverine-mediated nephropathy.

D. Dietrich, V. Wittmann, Marcia Y Maier, 2018, Chemico-biological interactions.

Mechanistic Insight into Nanomolar Binding of Multivalent Neoglycopeptides to Wheat Germ Agglutinin.

V. Wittmann, Philipp Rohse, 2016, Chemistry.

Probing multivalent carbohydrate-lectin interactions by an enzyme-linked lectin assay employing covalently immobilized carbohydrates.

V. Wittmann, Katja Rohmer, Caroline Maierhofer, 2007, Bioorganic & medicinal chemistry.

Time and space-resolved quantification of plasma membrane sialylation for measurements of cell function and neurotoxicity

M. Leist, Anna-Katharina Holzer, Petra Kranaster, 2019, Archives of Toxicology.

Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.

E. Wagner, Ulrich Lächelt, M. Höhn, 2014, Molecular pharmaceutics.

Simultaneous Detection of 14 Microcystin Congeners from Tissue Samples Using UPLC- ESI-MS/MS and Two Different Deuterated Synthetic Microcystins as Internal Standards

D. Dietrich, V. Fessard, Jonathan Puddick, 2019, Toxins.