A. B. C. Simas

发表

Nerve Agents’ Surrogates: Invaluable Tools for Development of Acetylcholinesterase Reactivators

K. Kuča, Samir F A Cavalcante, A. B. C. Simas, 2019, Current Organic Chemistry.

Acyclic ketene aminal phosphates derived from N,N-diprotected acetamides: stability and cross-couplings

A. B. C. Simas, D. L. Sales, Karla C. Pais, 2009 .

Evaluation of the performance of differently immobilized recombinant lipase B from Candida antarctica preparations for the synthesis of pharmacological derivatives in organic media

J. Pinto, M. Coelho, D. Freire, 2016 .

Selectivity Studies Towards the Synthesis of Novel Biaryl Ureas by (Hetero)Nanocatalysis: Size Control and Support Effects

A. B. C. Simas, L. S. Aguiar, J. D. Senra, 2016 .

Molecular Modeling and In Vitro Studies of a Neutral Oxime as a Potential Reactivator for Acetylcholinesterase Inhibited by Paraoxon

M. Valis, K. Kuča, T. França, 2018, Molecules.

Kinetic resolution of (±)-1,2-O-isopropylidene-3,6-di-O-benzyl-myo-inositol by lipases: An experimental and theoretical study on the reaction of a key precursor of chiral inositols

A. G. Cunha, M. G. Albuquerque, D. Freire, 2011 .

In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon

K. Kuča, T. França, J. Granjeiro, 2019, Biomolecules.

Recent Progress in Transition-Metal-Catalyzed C-N Cross-Couplings: Emerging Approaches Towards Sustainability

A. B. C. Simas, L. S. Aguiar, J. D. Senra, 2011 .

The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway

Nathalia Amado, J. Abreu, F. Gomes, 2022, International journal of molecular sciences.

On the kinetic resolution of sterically hindered myo-inositol derivatives in organic media by lipases

A. G. Cunha, M. Coelho, D. Freire, 2012 .

Heterocyclic Silyllithium Reagents as Precursors of Masked Hydroxyl Groups. Preliminary Results

A. B. C. Simas, G. Stork, 1996 .

Accurel MP 1000 as a support for the immobilization of lipase from Burkholderia cepacia: Application to the kinetic resolution of myo-inositol derivatives

M. Coelho, D. Freire, R. Fernández-Lafuente, 2015 .

Preparation of core–shell polymer supports to immobilize lipase B from Candida antarctica: Effect of the support nature on catalytic properties

A. G. Cunha, J. Pinto, D. Freire, 2014 .

Enantioselective palladium-catalyzed addition of 1,3-dicarbonyl compounds to an allene derivative.

B. Trost, J. Xie, B. Plietker, 2005, Chemistry.

Palladium on Layered Double Hydroxide: A Heterogeneous System for the Enol Phosphate Carbon-Oxygen Bond Activation in Aqueous Media

A. B. C. Simas, J. D. Senra, L. F. B. Malta, 2017 .

Synthesis and pharmacological evaluation of prenylated and benzylated pterocarpans against snake venom.

P. A. Melo, A. B. C. Simas, P. Costa, 2004, Bioorganic & medicinal chemistry letters.

Direct selective and controlled protection of multiple hydroxyl groups in polyols via iterative regeneration of stannylene acetals

A. B. C. Simas, Angelo A.T. da Silva, Tarcizio J. dos Santos Filho, 2009 .

Efficient desymmetrization of 4,6-di-O-benzyl-myo-inositol by Lipozyme TL-IM.

D. Freire, A. B. C. Simas, L. S. Aguiar, 2014, Carbohydrate research.

Synthesis of lipase/silica biocatalysts through the immobilization of CALB on porous SBA-15 and their application on the resolution of pharmaceutical derivatives and on nutraceutical enrichment of natural oil

D. Freire, R. Fernández-Lafuente, E. A. Manoel, 2021 .

Lipase Regioselective O‐Acetylations of a myo‐Inositol Derivative: Efficient Desymmetrization of 1,3‐Di‐O‐benzyl‐myo‐inositol

D. Freire, R. Fernández-Lafuente, E. A. Manoel, 2018 .

Kinetic resolution of a precursor for myo-inositol phosphates under continuous flow conditions

M. Coelho, D. Freire, E. A. Manoel, 2013 .

Experimental design of the kinetic resolution of a key precursor of high-value bioactive myo-inositols by an immobilized lipase

A. G. Cunha, D. Freire, M. Godoy, 2013 .

Efficient kinetic resolution of (±)-1,2-O-isopropylidene-3,6-di-O-benzyl-myo-inositol with the lipase B of Candida antarctica

A. G. Cunha, D. Freire, R. V. Almeida, 2010 .

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

K. Kuča, T. França, E. Nepovimova, 2021, Journal of Enzyme Inhibition and Medicinal Chemistry.

The use of aqueous potassium dichloroiodate for the synthesis of ureas

A. B. C. Simas, L. S. Aguiar, G. M. Viana, 2013 .

REGIOSELECTIVE LITHIATION OF RESORCINOL DERIVATIVES : SYNTHESIS OF MONO O-MOM- AND O-BENZYLRESORCINOLS PRENYLATED AT C-2 OR C-4 POSITIONS

A. B. C. Simas, P. Costa, A. L. Coelho, 1999 .

A Convenient Synthesis of (±)-4-Prenylpterocarpin

M. L. Vasconcellos, A. B. C. Simas, P. Costa, 1992 .

Regioselective lithiations of a pterocarpan skeleton: the first synthesis of (±)-4′-dehydroxycabenegrin A-I

A. B. C. Simas, P. Costa, A. J. Silva, 2001 .

Acetylcholinesterase: The “Hub” for Neurodegenerative Diseases and Chemical Weapons Convention

Roberto B. Sousa, K. Kuča, T. França, 2020, Biomolecules.

Kinetic resolution of (R,S)-1,2-isopropylidene glycerol (solketal) ester derivatives by lipases

D. Freire, C. P. Borges, A. Machado, 2011 .

Kinetic Resolution of 1,3,6-Tri‑O‑benzyl-myo-Inositol by Novozym 435: Optimization and Enzyme Reuse

A. G. Cunha, M. Coelho, D. Freire, 2012 .

Stereocontrolled elaboration of quaternary carbon centers involving the asymmetric michael-type alkylation of chiral imines: an efficient enantioselective access to (+)-vincamine

J. D'angelo, A. B. C. Simas, P. Costa, 1997 .

FORMAL ENANTIOSELECTIVE SYNTHESIS OF (+)-VINCAMINE. THE FIRST ENANTIOSELECTIVE ROUTE TO (+)-3,14-EPIVINCAMINE AND ITS ENANTIOMER

A. B. C. Simas, P. Costa, J. Alves, 1999 .

An expeditious and consistent procedure for tetrahydrofuran (THF) drying and deoxygenation by the still apparatus

L. L. Carvalho, A. B. C. Simas, V. L. P. Pereira, 2009 .

Ligand-free Suzuki–Miyaura reactions in PEG 300

O. Antunes, A. B. C. Simas, L. S. Aguiar, 2010 .

Hydroxypropyl‐α‐Cyclodextrin‐Capped Palladium Nanoparticles: Active Scaffolds for Efficient Carbon‐Carbon Bond Forming Cross‐Couplings in Water

R. C. Michel, O. Antunes, A. B. C. Simas, 2009 .

Synthesis of reference compounds related to Chemical Weapons Convention for verification and drug development purposes – a Brazilian endeavour

Samir F. de A. Cavalcante, R L de Paula, Daniel A. S. Kitagawa, 2018 .

Hydrophilic cyclodextrin protected Pd nanoclusters: insights into their size control and host–guest behavior

Y. Cordeiro, R. C. Michel, R. Simão, 2011 .

Effects of natural compounds on Xenopus embryogenesis: a potential read out for functional drug discovery targeting Wnt/β-catenin signaling.

Nathalia Amado, J. Abreu, R. Kuster, 2012, Current topics in medicinal chemistry.

Synthesis and in vitro evaluation of neutral aryloximes as reactivators of Electrophorus eel acetylcholinesterase inhibited by NEMP, a VX surrogate.

K. Kuča, Joyce S F D de Almeida, A. B. C. Simas, 2019, Chemico-biological interactions.

STRAIGHTFORWARD, ECONOMICAL PROCEDURES FOR MICROSCALE ELLMAN'S TEST FOR CHOLINESTERASE INHIBITION AND REACTIVATION

A. B. C. Simas, Monique Cardozo, R. B. Rodrigues, 2018 .

One-Pot Synthesis of NEMP, a VX Surrogate, and Reactivation of NEMP-Inhibited Electrophorus Eel Acetylcholinesterase by Current Antidotes

A. B. C. Simas, R. Rodrigues, T. Silva, 2018 .

The Use of Aqueous Potassium Dichloroiodate for the Synthesis of Ureas.

A. B. C. Simas, L. S. Aguiar, Marcela Guariento Vasconcelos, 2013 .