G. Leytze

发表

Covalent Dimerization of CD28/CTLA-4 and Oligomerization of CD80/CD86 Regulate T Cell Costimulatory Interactions*

P. Linsley, J. Bajorath, R. Peach, 1996, The Journal of Biological Chemistry.

Both Extracellular Immunoglobin-like Domains of CD80 Contain Residues Critical for Binding T Cell Surface Receptors CTLA-4 and CD28 (*)

Jürgen Bajorath, Peter S. Linsley, Alejandro Aruffo, 1995, The Journal of Biological Chemistry.

Interaction of the cytoplasmic tail of CTLA-4 (CD152) with a clathrin-associated protein is negatively regulated by tyrosine phosphorylation.

K. Bennett, P. Linsley, G. Schieven, 1997, Biochemistry.

Proliferation of human T lymphocytes induced with superantigens is not dependent on costimulation by the CD28 counter-receptor B7.

P. Linsley, N. Damle, G. Leytze, 1993, Journal of immunology.

Activation with superantigens induces programmed death in antigen‐primed CD4+ class II+ major histocompatibility complex T lymphocytes via a CD11a/CD18‐dependent mechanism

J. Ledbetter, N. Damle, G. Leytze, 1993, European journal of immunology.

Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes.

P. Linsley, A. Aruffo, J. Ledbetter, 1993, Journal of immunology.

Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7.

P. Linsley, A. Aruffo, J. Ledbetter, 1994, Journal of immunology.

Induction and reversal of long-lived specific unresponsiveness to a T-dependent antigen following CTLA4Ig treatment.

P. Linsley, G. Leytze, P. Wallace, 1995, Journal of immunology.

Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28

K. Constantine, L. Mueller, P. Linsley, 1997, Nature Structural Biology.

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1

P. Linsley, J. Bajorath, R. Peach, 1994, The Journal of experimental medicine.

Binding Stoichiometry of the Cytotoxic T Lymphocyte-associated Molecule-4 (CTLA-4)

P. Linsley, J. Bajorath, J. Bradshaw, 1995, The Journal of Biological Chemistry.

Costimulation via vascular cell adhesion molecule-1 induces in T cells increased responsiveness to the CD28 counter-receptor B7.

P. Linsley, H. Ochs, A. Aruffo, 1993, Cellular immunology.

Reduced CD3-mediated protein tyrosine phosphorylation in anergic CD4+ and CD8+ T cells.

M. Greene, A. Bhandoola, R. Hintzen, 1993, Journal of immunology.