P. Abreu

发表

Computational strategy for visualizing structures and teaching biochemistry

H. Castro, P. Abreu, Karina de Lima Carvalho, 2019, Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology.

DNA methylation: A promising target for the twenty-first century

H. Castro, E. Braggio, C. R. Rodrigues, 2008 .

Structure-function inferences based on molecular modeling, sequence-based methods and biological data analysis of snake venom lectins.

M. G. Albuquerque, H. Castro, C. R. Rodrigues, 2006, Toxicon : official journal of the International Society on Toxinology.

Antiviral Activity of 1,4-Disubstituted-1,2,3-Triazoles against HSV-1 in vitro

D. Bloom, P. Abreu, C. Buarque, 2020, Antiviral therapy.

Structure–activity relationship of a series of 1,2-dihydroquinoline analogues and binding mode with Vibrio cholerae dihydrofolate reductase

P. Abreu, V. Rabelo, Thienne F. Sampaio, 2016, Medicinal Chemistry Research.

Antibacterial profile against drug-resistant Staphylococcus epidermidis clinical strain and structure-activity relationship studies of 1H-pyrazolo[3,4-b]pyridine and thieno[2,3-b]pyridine derivatives.

H. Castro, C. R. Rodrigues, J. C. Borges, 2008, Bioorganic & medicinal chemistry.

Targeting Chikungunya virus by computational approaches: from viral biology to the development of therapeutic strategies

I. Paixão, P. Abreu, V. Rabelo, 2020, Expert opinion on therapeutic targets.

Molecular Modeling of a Phenyl‐Amidine Class of NMDA Receptor Antagonists and the Rational Design of New Triazolyl‐Amidine Derivatives

Raquel A. C. Leão, M. G. Albuquerque, H. Castro, 2013, Chemical biology & drug design.

Virtual screening identified compounds that bind to cyclin dependent kinase 2 and prevent herpes simplex virus type 1 replication and reactivation in neurons.

D. Bloom, T. Edwards, P. Abreu, 2019, Antiviral research.

Design strategies of oxidosqualene cyclase inhibitors: Targeting the sterol biosynthetic pathway

N. Romeiro, P. Abreu, V. Rabelo, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

Anti-inflammatory properties of pterocarpanquinone LQB-118 in mice.

M. N. Rennó, P. Abreu, P. Costa, 2016, Bioorganic & medicinal chemistry.

Effects of tauroursodeoxycholic acid on glucose homeostasis: Potential binding of this bile acid with the insulin receptor.

E. Carneiro, P. Abreu, R. A. Ribeiro, 2021, Life sciences.

Pro-Apoptotic Antitumoral Effect of Novel Acridine-Core Naphthoquinone Compounds against Oral Squamous Cell Carcinoma

B. K. Robbs, P. Abreu, V. Rabelo, 2022, Molecules.

Exploring 1,2,3-triazole derivatives by using in vitro and in silico assays to target new antifungal agents and treat Candidiasis

H. Castro, C. R. Rodrigues, V. Ferreira, 2017, Medicinal Chemistry Research.

Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products

A. Lourenço, H. Castro, P. H. Rampelotto, 2014, Front. Mar. Sci..

Class A β-lactamases and inhibitors: In silico analysis of the binding mode and the relationship with resistance.

H. Castro, P. Abreu, V. Rabelo, 2018, Journal of biotechnology.

Structural insights into the inhibition of the nsP2 protease from Chikungunya virus by molecular modeling approaches

P. Abreu, V. Rabelo, I. C. N. de Palmer Paixão, 2022, Journal of Molecular Modeling.

Structure–activity relationship of a series of 1,2-dihydroquinoline analogues and binding mode with Vibrio cholerae dihydrofolate reductase

P. Abreu, V. Rabelo, Thienne F. Sampaio, 2016, Medicinal Chemistry Research.

Synthesis, biological, and theoretical evaluations of new 1,2,3-triazoles against the hemolytic profile of the Lachesis muta snake venom.

H. Castro, C. R. Rodrigues, A. Fuly, 2009, Bioorganic & medicinal chemistry.

Synthesis, HIV-RT inhibitory activity and SAR of 1-benzyl-1H-1,2,3-triazole derivatives of carbohydrates.

H. Castro, C. R. Rodrigues, V. Ferreira, 2009, European journal of medicinal chemistry.

Identification of Nor-β-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain

A. Lourenço, H. Castro, C. R. Rodrigues, 2011, Current Microbiology.

Synthesis of new 4-(phenylamino)thieno(2,3-b)pyridines and derivatives of the novel benzo(b)thieno(3,2-h)-1,6-naphthyridine tetracyclic system

M. G. Albuquerque, H. Castro, C. R. Rodrigues, 2008 .

Identification of a Potential Lead Structure for Designing New Antimicrobials to Treat Infections Caused by Staphylococcus epidermidis-Resistant Strains

A. Lourenço, H. Castro, C. R. Rodrigues, 2008, Current Microbiology.

Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives.

H. Castro, C. R. Rodrigues, Cláudio Cirne-Santos, 2009, Bioorganic & medicinal chemistry.

Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases.

M. G. Albuquerque, H. Castro, C. R. Rodrigues, 2010, Journal of atherosclerosis and thrombosis.

Identification and characterization of a new member of snake venom thrombin inhibitors from Bothrops insularis using a proteomic approach.

H. Castro, C. R. Rodrigues, P. Ho, 2008, Toxicon : official journal of the International Society on Toxinology.

Targeting CYP51 for drug design by the contributions of molecular modeling

Carlos R Rodrigues, Helena C Castro, H. Castro, 2017, Fundamental & clinical pharmacology.

Marine Diterpenes: Molecular Modeling of Thrombin Inhibitors with Potential Biotechnological Application as an Antithrombotic

H. Castro, P. Abreu, L. Terra, 2017, Marine drugs.

Looking at the proteases from a simple perspective

Natália I V Loureiro, Carlos R Rodrigues, Helena C Castro, 2011, Journal of molecular recognition : JMR.

Perezone, from the gorgonian Pseudopterogorgia rigida, induces oxidative stress in human leukemia cells

P. Jimenez, L. Costa-Lotufo, P. Abreu, 2015 .

Mechanism of resistance to acyclovir in thymidine kinase mutants from Herpes simplex virus type 1: a computational approach

N. Romeiro, I. Paixão, P. Abreu, 2019, Journal of biomolecular structure & dynamics.

Physical Education: Adaptations and Benefits for Deaf Students

H. C. Castro, P. Abreu, Alex Sandro Lins Ramos, 2019, Creative Education.

Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel

H. Castro, C. R. Rodrigues, P. Sathler, 2014, Journal of enzyme inhibition and medicinal chemistry.

Chemoselective Synthesis of Mannich Adducts from 1,4-Naphthoquinones and Profile as Autophagic Inducers in Oral Squamous Cell Carcinoma

B. K. Robbs, B. Pontes, V. Ferreira, 2022, Molecules.

Virtual screening and drug repositioning as strategies for the discovery of new antifungal inhibitors of oxidosqualene cyclase

N. Romeiro, P. Abreu, V. Rabelo, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Synthesis and Antileishmanial Activity of New 1-Aryl-1H-Pyrazole-4- Carboximidamides Derivatives

H. Castro, C. R. Rodrigues, L. Leon, 2011 .

Identification of Pyrroloformamide as a Cytokinesis Modulator

J. L. La Clair, P. Jimenez, P. Abreu, 2014, Chembiochem : a European journal of chemical biology.

Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives.

H. Castro, C. R. Rodrigues, P. Sathler, 2017, Chemical & pharmaceutical bulletin.

Oxoquinoline Derivatives: Identification and Structure–Activity Relationship (SAR) Analysis of New Anti-HSV-1 Agents

H. Castro, C. R. Rodrigues, V. Ferreira, 2011, Current Microbiology.

Exploring 1,2,3-triazole derivatives by using in vitro and in silico assays to target new antifungal agents and treat Candidiasis

H. Castro, C. R. Rodrigues, V. Ferreira, 2017, Medicinal Chemistry Research.

Anticancer Activity and Molecular Targets of Piper cernuum Substances in Oral Squamous Cell Carcinoma Models

B. K. Robbs, C. Carollo, A. Macedo, 2023, Biomedicines.

Tuberculosis: Finding a New Potential Antimycobacterium Derivative in a Aldehyde–Arylhydrazone–Oxoquinoline Series

H. Castro, C. R. Rodrigues, M. Lourenço, 2012, Current Microbiology.

Synthesis of 5-amino-1-aryl-3-methyl-1H-pyrazole-4-carbonitriles, Antifungal Activity and In Silico Analysis

H. Castro, A. Bernardino, P. Abreu, 2020 .

Structural insights into the inhibition of the nsP2 protease from Chikungunya virus by molecular modeling approaches

P. Abreu, V. Rabelo, I. C. N. de Palmer Paixão, 2022, Journal of Molecular Modeling.

Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives

Cláudio Cirne-Santos, Caroline Barros, R. Faria, 2022, Journal of the Brazilian Chemical Society.

DNA methylation: a promising target for the twenty-first century.

H. Castro, E. Braggio, C. R. Rodrigues, 2008, Expert opinion on therapeutic targets.

Molecular Modeling of a Phenyl‐Amidine Class of NMDA Receptor Antagonists and the Rational Design of New Triazolyl‐Amidine Derivatives

Raquel A. C. Leão, M. G. Albuquerque, H. Castro, 2013, Chemical Biology and Drug Design.

Chloroquinolone carboxamide derivatives as new anti-HSV-1 promising drugs.

H. Castro, P. Abreu, M. de Souza, 2022, Current topics in medicinal chemistry.

In silico structural characteristics and α-amylase inhibitory properties of Ric c 1 and Ric c 3, allergenic 2S albumins from Ricinus communis seeds.

H. Castro, O. Machado, P. Abreu, 2011, Journal of agricultural and food chemistry.