Christopher R. Lupfer

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The ketone metabolite β-hydroxybutyrate blocks NLRP 3 inflammasome – mediated inflammatory disease

P. A. Crawford, E. Alnemri, T. Horvath, 2015 .

A Novel Lactococcal Vaccine Expressing a Peptide from the M2 Antigen of H5N2 Highly Pathogenic Avian Influenza A Virus Prolongs Survival of Vaccinated Chickens

B. Geller, Christopher R. Lupfer, Kaleb A. Reese, 2013, Veterinary medicine international.

The role of inflammasome modulation in virulence

T. Kanneganti, Christopher R. Lupfer, 2012, Virulence.

Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease

P. A. Crawford, E. Alnemri, T. Horvath, 2015, Nature Medicine.

Common Differences: The Ability of Inflammasomes to Distinguish Between Self and Pathogen Nucleic Acids During Infection.

Christopher R. Lupfer, P. Anand, Meagan Rippee-Brooks, 2019, International review of cell and molecular biology.

Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance

T. Kanneganti, Christopher R. Lupfer, K. Stokes, 2017, Journal of Virology.

Nucleotide Oligomerization and Binding Domain 2-Dependent Dendritic Cell Activation Is Necessary for Innate Immunity and Optimal CD8+ T Cell Responses to Influenza A Virus Infection

P. Thomas, T. Kanneganti, Christopher R. Lupfer, 2014, Journal of Virology.

Treatment of human respiratory syncytial virus infected Balb/C mice with the proteasome inhibitor bortezomib (Velcade, PS-341) results in increased inflammation and mortality.

Christopher R. Lupfer, M. Pastey, K. Patton, 2010, Toxicology.

Decreased replication of human respiratory syncytial virus treated with the proteasome inhibitor MG-132.

Christopher R. Lupfer, M. Pastey, 2010, Virus research.

Antifungal Norditerpene Oidiolactones from the Fungus Oidiodendron truncatum, a Potential Biocontrol Agent for White-Nose Syndrome in Bats.

R. Blanchette, B. Held, C. Salomon, 2020, Journal of natural products.

Inflammasome activation by nucleic acids and nucleosomes in sterile inflammation… or is it sterile?

T. Kanneganti, Christopher R. Lupfer, A. Rodriguez, 2017, The FEBS journal.

Sodium Pyruvate Nasal Spray Reduces the Severity of Nasal Inflammation and Congestion in Patients with Allergic Rhinitis

Christopher R. Lupfer, Alain Martin, Ronald Amen, 2022, Journal of aerosol medicine and pulmonary drug delivery.

Inhalation of Sodium Pyruvate to Reduce the Symptoms and Severity of Respiratory Diseases Including COVID-19, Long COVID, and Pulmonary Fibrosis

Christopher R. Lupfer, Ronald Amen, Riley Nadler, 2021, European Journal of Respiratory Medicine.

Unsolved Mysteries in NLR Biology

T. Kanneganti, Christopher R. Lupfer, 2013, Front. Immunol..

What came first, the virus or the egg: Innate immunity during viral coinfections

Christopher R. Lupfer, Meagan Rippee-Brooks, Riley N Marcinczyk, 2020, Immunological reviews.

Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection

M. Lamkanfi, P. Vogel, T. Kanneganti, 2014, PLoS pathogens.

Increased Survivorship and Altered Cytokine Profile from Treatment of Influenza A H1N1-Infected Mice with Ekybion: A Drug Complex of Natural Extracts and Inorganic Compounds

Christopher R. Lupfer, M. Pastey, Maciej Maselko, 2010, Evidence-based complementary and alternative medicine : eCAM.

The Inflammasome: Regulation of Nitric Oxide and Antimicrobial Host Defence.

H. Zaki, Christopher R. Lupfer, Rajalaksmy A. Ramachandran, 2018, Advances in microbial physiology.

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Paul G. Thomas, Peter Vogel, Mondira Kundu, 2013, Nature Immunology.

Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers

D. A. Stein, P. Iversen, Christopher R. Lupfer, 2008, Archives of Virology.

Inflammasome control of viral infection.

T. Kanneganti, Christopher R. Lupfer, Ankit Malik, 2015, Current opinion in virology.

Sodium Pyruvate Ameliorates Influenza A Virus Infection In Vivo

Christopher R. Lupfer, J. M. Reel, 2020, bioRxiv.

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection

Si Ming Man, G. Neale, M. Lamkanfi, 2016, The Journal of experimental medicine.

Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae

J. McCullers, A. Smith, T. Kanneganti, 2019, PloS one.

Editorial: Role of NOD-Like Receptors in Infectious and Immunological Diseases

H. Zaki, Christopher R. Lupfer, P. Anand, 2020, Frontiers in Immunology.

Integrating Inflammasome Signaling in Sexually Transmitted Infections

Christopher R. Lupfer, P. Anand, 2016, Trends in immunology.

The Role of Inflammasomes in Viral Infection

T. Kanneganti, Christopher R. Lupfer, 2011 .

Pyruvate affects inflammatory responses of macrophages during influenza A virus infection

Christopher R. Lupfer, J. M. Reel, Hazar Abusalamah, 2020, Virus Research.

The expanding role of NLRs in antiviral immunity

T. Kanneganti, Christopher R. Lupfer, 2013, Immunological reviews.

Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59

R. Webby, T. Kanneganti, A. Ellebedy, 2011, Proceedings of the National Academy of Sciences.

Inhibition of Multiple Subtypes of Influenza A Virus in Cell Cultures with Morpholino Oligomers

D. A. Stein, Jianzhu Chen, P. Iversen, 2006, Antimicrobial Agents and Chemotherapy.

Interaction of the Human Respiratory Syncytial Virus matrix protein with cellular adaptor protein complex 3 plays a critical role in trafficking

Christopher R. Lupfer, M. Pastey, Maciej Maselko, 2017, PloS one.