C. Eastman

发表

Functional definition of seizure provides new insight into post-traumatic epileptogenesis

Ramon Diaz-Arrastia, D. R. Verley, Shahin Hakimian, 2009, Brain : a journal of neurology.

Mild passive focal cooling prevents epileptic seizures after head injury in rats

D. R. Verley, J. Ojemann, M. Smyth, 2013, Annals of neurology.

Differential expression of the astrocytic enzymes 3-hydroxyanthranilic acid oxygenase, kynurenine aminotransferase and glutamine synthetase in seizure-prone and non-epileptic mice

R. Schwarcz, C. Eastman, A. Chapman, 1994, Epilepsy Research.

Is 3-hydroxykynurenine an endogenous neurotoxin in Huntington's disease?

T. Guilarte, C. Eastman, 1993, Journal of the Neurological Sciences.

Cytotoxicity of 3-hydroxykynurenine in a neuronal hybrid cell line

T. Guilarte, C. Eastman, 1989, Brain Research.

Cytotoxicity of 3-hydroxykynurenine: implications for CNS damage in neonatal vitamin B-6 deficiency.

T. Guilarte, C. Eastman, 1991, Advances in experimental medicine and biology.

Metabolism of [5‐3H]Kynurenine in the Rat Brain In Vivo: Evidence for the Existence of a Functional Kynurenine Pathway

R. Schwarcz, P. Guidetti, C. Eastman, 1995, Journal of neurochemistry.

Uptake of 3-hydroxykynurenine measured in rat brain slices and in a neuronal cell line

T. Guilarte, J. Lever, C. Eastman, 1992, Brain Research.

Disposition of the aromatic amine, benzidine, in the rat: characterization of mutagenic urinary and biliary metabolites.

K. F. Scott, C. Eastman, R. Rodgers, 1984, Toxicology and applied pharmacology.

in the Spinal Cord Slice Mu Opiates Inhibit Long-Term Potentiation Induction

J. Sandkühler, R. Donahue, B. Taylor, 2015 .

Mu opiates inhibit long-term potentiation induction in the spinal cord slice.

C. Chavkin, C. Chavkin, C. Eastman, 2001, Journal of neurophysiology.

The role of hydrogen peroxide in the in vitro cytotoxicity of 3-hydroxykynurenine

T. Guilarte, C. Eastman, 1990, Neurochemical Research.

Synthesis and enantiomeric resolution of tritiated (D,L)‐3‐hydroxykynurenine

T. Guilarte, J. Lever, C. Eastman, 1990 .

Increased Brain Quinolinic Acid Production in Mice Infected with a Hamster Neurotropic Measles Virus

R. Schwarcz, K. Kristensson, A. Löve, 1994, Experimental Neurology.

Trimethyltin ototoxicity in albino rats.

C. Eastman, L. Fechter, J. Young, 1987, Neurotoxicology and teratology.

Vitamin B-6, kynurenines, and central nervous system function: developmental aspects

T. Guilarte, C. Eastman, 1992 .

Modeling Post-Traumatic Epilepsy for Therapy Development

John W. Miller, R. D’Ambrosio, G. Curia, 2016 .

Temporal Expression of Neuroinflammatory and Oxidative Stress Markers and Prostaglandin E2 Receptor EP2 Antagonist Effect in a Rat Model of Epileptogenesis.

R. Dingledine, R. D’Ambrosio, Varun Rawat, 2022, ACS pharmacology & translational science.

Inadequate experimental methods and erroneous epilepsy diagnostic criteria result in confounding acquired focal epilepsy with genetic absence epilepsy

John W. Miller, R. D’Ambrosio, C. Eastman, 2015, 1509.01206.

Optimized methods for epilepsy therapy development using an etiologically realistic model of focal epilepsy in the rat

R. D’Ambrosio, N. Temkin, Jason S. Fender, 2015, Experimental Neurology.

Antiepileptic and Antiepileptogenic Performance of Carisbamate after Head Injury in the Rat: Blind and Randomized Studies

D. R. Verley, R. D’Ambrosio, Tessandra H Stewart, 2011, Journal of Pharmacology and Experimental Therapeutics.

Chronic dysfunction of astrocytic inwardly rectifying K+ channels specific to the neocortical epileptic focus after fluid percussion injury in the rat.

Peter A. Groblewski, D. R. Verley, P. Groblewski, 2010, Journal of neurophysiology.

ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat

D. R. Verley, R. D’Ambrosio, N. Temkin, 2010, Experimental Neurology.

Metabolism of the human carcinogen, benzidine, in the isolated perfused rat liver.

K. F. Scott, C. Eastman, R. Rodgers, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Modulating neuroinflammation and oxidative stress to prevent epilepsy and improve outcomes after traumatic brain injury

R. D’Ambrosio, C. Eastman, T. Ganesh, 2019, Neuropharmacology.

Running title: astrocytes in posttraumatic epileptogenesis CHRONIC DYSFUNCTION OF ASTROCYTIC INWARDLY RECTIFYING K+ 1 CHANNELS SPECIFIC TO THE NEOCORTICAL EPILEPTIC FOCUS AFTER FLUID 2 PERCUSSION INJURY IN THE RAT

Peter A. Groblewski, D. R. Verley, P. Groblewski, 2010 .

Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation

R. D’Ambrosio, E. Perucca, C. Eastman, 2013, Expert review of neurotherapeutics.

Preclinical pharmacokinetics and tolerability of a novel meglumine‐based parenteral solution of topiramate and topiramate combinations for treatment of status epilepticus

H. Goodkin, R. D’Ambrosio, W. Löscher, 2023, Epilepsia.

Therapeutic Effects of Time-Limited Treatment with Brivaracetam on Posttraumatic Epilepsy after Fluid Percussion Injury in the Rat

R. D’Ambrosio, P. Klein, Jason S. Fender, 2021, The Journal of Pharmacology and Experimental Therapeutics.