C. Frelin

M. Dehouck, R. Cecchelli, G. Torpier, 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Sensitization by calyculin A of brain capillary endothelial cells to endothelin‐1

P. Vigne, C. Frelin, J. Breittmayer, 1995, British journal of pharmacology.

The irreversibility of endothelin action is a property of a late intracellular signalling event.

R. Marsault, P. Vigne, C. Frelin, 1991, Biochemical and biophysical research communications.

Competitive and non competitive interactions of BQ-123 with endothelin ETA receptors.

P. Vigne, C. Frelin, J. Breittmayer, 1993, European journal of pharmacology.

Na(+)-K(+)-Cl- cotransporter of brain capillary endothelial cells. Properties and regulation by endothelins, hyperosmolar solutions, calyculin A, and interleukin-1.

P. Vigne, C. Frelin, A. L. López Farré, 1994, The Journal of biological chemistry.

Palytoxin. Recent electrophysiological and pharmacological evidence for several mechanisms of action.

C. Van Renterghem, C. Frelin, 1995, General pharmacology.

Ethylisopropyl-amiloride: a new and highly potent derivative of amiloride for the inhibition of the Na+/H+ exchange system in various cell types.

M. Lazdunski, P. Vigne, C. Frelin, 1983, Biochemical and biophysical research communications.

Endothelins inhibit adenylate cyclase in brain capillary endothelial cells.

C. Frelin, A. Ladoux, 1991, Biochemical and biophysical research communications.

The Na+/K+/Cl- cotransport in C6 glioma cells. Properties and role in volume regulation.

M. Lazdunski, C. Frelin, O. Chassande, 1988, European journal of biochemistry.

[3H]phenamil, a radiolabelled diuretic for the analysis of the amiloride-sensitive Na+ channels in kidney membranes.

M. Lazdunski, P. Barbry, P. Vigne, 1986, Biochemical and biophysical research communications.

Biochemical characterization of the Na+/K+/Cl- co-transport in chick cardiac cells.

M. Lazdunski, C. Frelin, O. Chassande, 1986, Biochemical and biophysical research communications.

Biochemical evidence for pharmacological similarities between alpha-adrenoreceptors and voltage-dependent Na+ and Ca++ channels.

M. Lazdunski, P. Vigne, C. Frelin, 1982, Biochemical and biophysical research communications.

The growth of heart cells in culture. Evidences for a multiple activation of the pleiotypic program.

C. Frelin, 1978, Biochimie.

Pleiotypic response of rat heart cells in culture to serum stimulation.

C. Frelin, P. Padieu, 1976, Biochimie.

Na+ channels as sites of action of the cardioactive agent DPI 201-106 with agonist and antagonist enantiomers.

M. Lazdunski, G. Romey, U. Quast, 1987, Proceedings of the National Academy of Sciences of the United States of America.

3,4 Dichlorobenzamil‐sensitive, monovalent cation channel induced by palytoxin in cultured aortic myocytes

C. Renterghem, C. Frelin, 1993, British journal of pharmacology.

The effect of extracellular calcium on the contractile action of endothelin.

R. Marsault, P. Vigne, C. Frelin, 1990, Biochemical and biophysical research communications.

Characterization and Channel Coupling of the P2Y12Nucleotide Receptor of Brain Capillary Endothelial Cells*

E. Barnard, Y. Wong, D. Brown, 2002, The Journal of Biological Chemistry.

The regulation of protein turnover in newborn rat heart cell cultures.

C. Frelin, 1980, The Journal of biological chemistry.

Cross Talk Among Cyclic AMP, Cyclic GMP, and Ca2+ ‐Dependent Intracellular Signalling Mechanisms in Brain Capillary Endothelial Cells

P. Vigne, C. Frelin, Lise Lund, 1994, Journal of neurochemistry.

Endothelins activate phospholipase A2 in brain capillary endothelial cells

P. Vigne, C. Frelin, 1994, Brain Research.

Coexpression of endothelial markers and CD14 by cytokine mobilized CD34+ cells under angiogenic stimulation.

C. Frelin, J. Bayle, D. Nakul-Aquaronne, 2003, Cardiovascular research.

IL1 and TNF alpha induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway.

C. Damais, P. Vigne, C. Frelin, 1993, Brain research.

Actions, interactions, and apparent affinities of various ceveratrum alkaloids at sodium channels of cultured neuroblastoma and cardiac cells

M. Lazdunski, C. Frelin, P. Honerjäger, 1982, Naunyn-Schmiedeberg's Archives of Pharmacology.

Activity of adenosine diphosphates and triphosphates on a P2YT‐type receptor in brain capillary endothelial cells

E. Barnard, J. Simon, P. Vigne, 2001, British journal of pharmacology.

The P2Y purinoceptor in rat brain microvascular endothelial cells couple to inhibition of adenylate cyclase

J. Neary, E. Barnard, P. Vigne, 1996, British journal of pharmacology.

ADP induces inositol phosphate-independent intracellular Ca2+ mobilization in brain capillary endothelial cells.

P. Vigne, C. Frelin, J. Breittmayer, 1993, The Journal of biological chemistry.

Analysis of the influence of nucleotidases on the apparent activity of exogenous ATP and ADP at P2Y1 receptors

P. Vigne, C. Frelin, Jean Philippe Breittmayer, 1998, British journal of pharmacology.

Endothelins activate Na+/H+ exchange in brain capillary endothelial cells via a high affinity endothelin-3 receptor that is not coupled to phospholipase C.

P. Vigne, C. Frelin, A. Ladoux, 1991, The Journal of biological chemistry.

USE OF INHIBITORS OF eIF5A HYPUSINYLATION TO TREAT DISEASES AND ISCHEMIC HYPOXIC

P. Vigne, C. Frelin, M. Tauc, 2010 .

THE EGG WHITE PROTEIN EVIDENCE FOR RATITE AFFINITIES

C. G. Sibley, C. Frelin, 2008 .

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome.

N. Melis, Amine Belaid, B. Mograbi, 2017, Journal of the American Society of Nephrology : JASN.

Human kidney amiloride-binding protein: cDNA structure and functional expression.

A. Ullrich, M. Champe, P. Barbry, 1990, Proceedings of the National Academy of Sciences of the United States of America.

The appearance of voltage-sensitive Na+ channels during the in vitro differentiation of embryonic chick skeletal muscle cells.

M. Lazdunski, G. Romey, P. Vigne, 1981, The Journal of biological chemistry.

Ontogeny of the (Na+,K+)-ATPase during chick skeletal myogenesis.

M. Lazdunski, P. Vigne, C. Frelin, 1982, The Journal of biological chemistry.

Biochemical studies of the structure, mechanism and differentiation of the voltage-sensitive sodium channel

M. Lazdunski, J. Barhanin, G. Ponzio, 1980, Neurochemistry International.

The interaction of ervatamine and epiervatamine with the action potential Na+ ionophore.

M. Lazdunski, G. Ponzio, G. Romey, 1981, Molecular pharmacology.

Biochemical properties of the Na+/H+ exchange system in rat brain synaptosomes. Interdependence of internal and external pH control of the exchange activity.

P Barbry, M. Lazdunski, P. Barbry, 1985, The Journal of biological chemistry.

Interaction of tralomethrin, tralocythrin, and related pyrethroids in Na+ channels of insect and mammalian neuronal cells

C. Frelin, M. Roche, P. Bruneau, 1985 .

Activation of Cardiac Endothelium as a Compensatory Component in Endotoxin-Induced Cardiomyopathy: Role of Endothelin, Prostaglandins, and Nitric Oxide

A. Mebazaa, G. D. De Keulenaer, D. Brutsaert, 2001, Circulation.

Regulation of Vascular Endothelial Growth Factor Expression in Human Keratinocytes by Retinoids*

C. Frelin, A. Ladoux, M. Lenoir, 2000, The Journal of Biological Chemistry.

Hypoxia-induced transcriptional activation of vascular endothelial growth factor is inhibited by serum.

C. Frelin, G. D’angelo, A. Ladoux, 2000, Biochemical and biophysical research communications.

Amiloride and its analogs as tools to inhibit Na+ transport via the Na+ channel, the Na+/H+ antiport and the Na+/Ca2+ exchanger.

M. Lazdunski, P. Barbry, P. Vigne, 1988, Biochimie.

Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids.

C. Frelin, A. Ladoux, M. Lenoir, 1998, The Journal of biological chemistry.

Cyclosporin A Prevents the Hypoxic Adaptation by Activating Hypoxia-inducible Factor-1α Pro-564 Hydroxylation*

E. Duplan, P. Vigne, C. Frelin, 2003, The Journal of Biological Chemistry.

The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.

M. Lazdunski, P. Vigne, C. Frelin, 1983, The Journal of biological chemistry.

[3H]Ethylpropylamiloride, a ligand to analyze the properties of the Na+/H+ exchange system in the membranes of normal and hypertrophied kidneys.

M. Lazdunski, P. Barbry, P. Vigne, 1985, Journal of Biological Chemistry.

Guanabenz, guanochlor, guanoxan and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes.

M. Lazdunski, P. Vigne, C. Frelin, 1989, European journal of pharmacology.

Intracellular pH of Cardiac Cells: Hormonal Regulation and Role in Ischemia

M. Lazdunski, P. Vigne, C. Frelin, 1989 .

Properties of the Na+-dependent Cl-/HCO3- exchange system in U937 human leukemic cells.

J. Abita, C. Frelin, E. Cragoe, 1987, European journal of biochemistry.

Coordinated Up-regulation by hypoxia of adrenomedullin and one of its putative receptors (RDC-1) in cells of the rat blood-brain barrier.

A Ladoux, C Frelin, C. Frelin, 2000, The Journal of biological chemistry.

ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptor.

C. Gachet, P. Vigne, C. Léon, 1998, Molecular pharmacology.

Characterization of the effects of 2‐methylthio‐ATP and 2‐chloro‐ATP on brain capillary endothelial cells: similarities to ADP and differences from ATP

P. Vigne, C. Frelin, J. Breittmayer, 1994, British journal of pharmacology.

The role of the Na+/H+ exchange system in cardiac cells in relation to the control of the internal Na+ concentration. A molecular basis for the antagonistic effect of ouabain and amiloride on the heart.

M. Lazdunski, P. Vigne, C. Frelin, 1984, The Journal of biological chemistry.

Na+ channels with high and low affinity tetrodotoxin binding sites in the mammalian skeletal muscle cell. Difference in functional properties and sequential appearance during rat skeletal myogenesis.

M. Lazdunski, P. Vigne, C. Frelin, 1983, The Journal of biological chemistry.

Myocardial electrophysiology: intracellular studies on heart cell cultures from newborn rats.

P. Athias, C. Frelin, J. Klepping, 1979, Pathologie-biologie.

The Na+/H+ antiport is activated by serum and phorbol esters in proliferating myoblasts but not in differentiated myotubes. Properties of the activation process.

M. Lazdunski, P. Vigne, C. Frelin, 1985, The Journal of biological chemistry.

Endothelin mobilizes Ca2+ from a caffeine- and ryanodine-insensitive intracellular pool in rat atrial cells.

R. Marsault, P. Vigne, C. Frelin, 1990, The Journal of biological chemistry.

Diet dependent longevity and hypoxic tolerance of adult Drosophila melanogaster

P. Vigne, C. Frelin, 2007, Mechanisms of Ageing and Development.

A Low Protein Diet Increases the Hypoxic Tolerance in Drosophila

P. Vigne, C. Frelin, 2006, PloS one.

C-type natriuretic peptide is a potent activator of guanylate cyclase in endothelial cells from brain microvessels.

P. Vigne, C. Frelin, 1992, Biochemical and biophysical research communications.

ATP and UTP increase secretion of bronchial inhibitor by human tracheal gland cells in culture.

M. Merten, C. Figarella, C. Frelin, 1993, The American journal of physiology.

Endothelin stimulates phosphatidylinositol hydrolysis and DNA synthesis in brain capillary endothelial cells.

R. Marsault, P. Vigne, C. Frelin, 1990, The Biochemical journal.

Effect of environmental factors and tissue culture methodology in producing and studying cultured cardiac cells.

P. Athias, C. Frelin, P. Padieu, 1976, Recent advances in studies on cardiac structure and metabolism.

Daily Variations of Serum Glucose Levels in Moulting Redpolls Acanthis flammea and in Migrating Robins Erithacus rubecula

C. Frelin, 1974 .

The lipoprotein lipase activity in cultured beating heart cells of the post-natal rat.

C. Frelin, A. Pinson, P. Padieu, 1974, Biochimie.

IL1 and TNFα induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway

C. Damais, P. Vigne, C. Frelin, 1993, Brain Research.

Activation by Nitric Oxide of Guanylate Cyclase in Endothelial Cells from Brain Capillaries

R. Marsault, C. Frelin, Robert Marsault, 1992, Journal of neurochemistry.

The effect of PPADS as an antagonist of inositol (1,4,5)trisphosphate induced intracellular calcium mobilization

P. Pacaud, P. Vigne, C. Frelin, 1996, British journal of pharmacology.

Mechanisms of vasoconstriction.

C Frelin, C. Frelin, 1991, American heart journal.

The interaction of sea anemone and scorpion neurotoxins with tetrodotoxin-resistant Na+ channels in rat myoblasts. A comparison with Na+ channels in other excitable and non-excitable cells.

M. Lazdunski, P. Vigne, H. Schweitz, 1984, Molecular pharmacology.

Strong Dietary Restrictions Protect Drosophila against Anoxia/Reoxygenation Injuries

P. Vigne, C. Frelin, M. Tauc, 2009, PloS one.

Tetrodotoxin-sensitive and tetrodotoxin-resistant Na+ channels differ in their sensitivity to Cd2+ and Zn2+.

M. Lazdunski, C. Cognard, P. Vigne, 1986, European journal of pharmacology.

Properties and functions of a neuromedin-B-preferring bombesin receptor in brain microvascular endothelial cells.

C. Van Renterghem, P. Vigne, C. Frelin, 1995, European journal of biochemistry.

Benzoyl ATP is an antagonist of rat and human P2Y1 receptors and of platelet aggregation.

C. Gachet, P. Vigne, B. Hechler, 1999, Biochemical and biophysical research communications.

The specificity of the sodium channel for monovalent cations.

M. Lazdunski, P. Vigne, C. Frelin, 1981, European journal of biochemistry.

Et-1 and Et-3 actions mediated by cloned ETA endothelin receptors exhibit different sensitivities to BQ-123.

D. Guédin, M. Cousin, C. Frelin, 1996, Biochemical and biophysical research communications.

Function of Vasoactive Factors in the Cerebral Microcirculation

P. Vigne, C. Frelin, A. Ladoux, 1992, Journal of cardiovascular pharmacology.

Identification of an amiloride sensitive Na+/H+ exchange system in brain synaptosomes

M. Lazdunski, P. Vigne, S. Sauvaigo, 1984, Brain Research.

Palytoxin acidifies chick cardiac cells and activates the Na+/H+ antiporter

P. Vigne, C. Frelin, Jean-Philippe Breittmayer, 1990, FEBS letters.

An in vitro system to study the action potential sodium channel

M. Lazdunski, G. Ponzio, R. Chicheportiche, 1980, FEBS letters.

Corticosteroid receptors in cells derived from rat brain microvessels: mRNA identification and aldosterone binding.

P. Eldin, C. Frelin, M. Claire, 1992, The American journal of physiology.

Astrocytes Are Target Cells for Endothelins and Sarafotoxin

R. Marsault, P. Vigne, C. Frelin, 1990, Journal of neurochemistry.

PPADS inhibits P2Y1 purinoceptors in rat brain capillary endothelial cells and in rat ileal myocytes by an indirect mechanism.

P. Pacaud, P. Vigne, C. Frelin, 1998, Biochemical and biophysical research communications.

The regulation of the cytoplasmic free Ca2+ concentration in aortic smooth muscle cells (A7r5 line) after stimulation by vasopressin and bombesin.

M. Lazdunski, P. Vigne, C. Frelin, 1988, European journal of biochemistry.

Analysis of the hypoxia-sensing pathway in Drosophila melanogaster.

E. Duplan, P. Vigne, P. Thérond, 2006, The Biochemical journal.

Plasticity of the responses to chronic hypoxia and dietary restriction in an aged organism: Evidence from the Drosophila model

P. Vigne, C. Frelin, 2007, Experimental Gerontology.

Cardiac and lung VEGF mRNA expression in chronically hypoxic and monocrotaline-treated rats.

S. Eddahibi, E. Teiger, S. Adnot, 1998, Chest.

Contributions of NO synthase and heme oxygenase to cGMP formation by cytokine and hemin treated brain capillary endothelial cells.

P. Vigne, C. Frelin, A. Ladoux, 1995, Biochemical and biophysical research communications.

High reactivity of aortic fibroblasts to vasoactive agents: endothelins, bradykinin and nucleotides.

R. Marsault, P. Vigne, C. Frelin, 1992, Biochemical and biophysical research communications.

Thapsigargin, a new inotropic agent, antagonizes action of endothelin-1 in rat atrial cells.

P. Vigne, C. Frelin, J. Breittmayer, 1992, American Journal of Physiology.