M. Lucas

发表

Characterization and in vitro translation of polyadenylated messenger ribonucleic acid from Neurospora crassa

M. Lucas, J. W. Jacobson, N. Giles, 1977, Journal of bacteriology.

Potent and highly selective benzimidazole inhibitors of PI3-kinase delta.

P. Savy, E. Bradley, M. Ultsch, 2012, Journal of medicinal chemistry.

Targeting the SYK-BTK axis for the treatment of immunological and hematological disorders: recent progress and therapeutic perspectives.

Christopher S. Stevenson, Seng-Lai Tan, C. Stevenson, 2013, Pharmacology & therapeutics.

Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity.

Daniel F Tardiff, K. Rhodes, J. Piotrowski, 2018, Cell reports.

Antioxidant response to NaCl stress in salt-tolerant and salt-sensitive cultivars of cotton

M. Lucas, D. Gossett, E. Millhollon, 1994 .

Characterization of 5.8S ribosomal ribonucleic acid in Neurospora crassa

L. Vanderhoef, M. Lucas, 1975, Journal of bacteriology.

Rational design of highly selective spleen tyrosine kinase inhibitors.

Johannes C. Hermann, A. Kuglstatter, K. Luk, 2012, Journal of medicinal chemistry.

Antioxidant Response to NaCl Stress in a Control and an NaCl-Tolerant Cotton Cell Line Grown in the Presence of Paraquat, Buthionine Sulfoximine, and Exogenous Glutathione

M. Lucas, D. Gossett, E. Millhollon, 1996, Plant physiology.

The effects of NaCl on antioxidant enzyme activities in callus tissue of salt-tolerant and salt-sensitive cotton cultivars (Gossypium hirsutum L.)

M. Lucas, D. Gossett, E. Millhollon, 1994, Plant Cell Reports.

The relationship between yield and the antioxidant defense system in tomatoes grown under heat stress.

M. Lucas, H. Hanna, H. Y. Hanna, 1996, Free radical research.

Chapter Eleven – Emerging Targets for the Treatment of Idiopathic Pulmonary Fibrosis

D. Budd, M. Lucas, 2013 .

Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.

Christopher S. Stevenson, C. Stevenson, A. Narayanan, 2012, Journal of medicinal chemistry.

Potent and selective inhibitors of PI3Kδ: obtaining isoform selectivity from the affinity pocket and tryptophan shelf.

Steve Price, A. Nadin, BinQing Wei, 2013, Bioorganic & medicinal chemistry letters.

The influence of alpha-amanitin on the NaCl-induced up-regulation of antioxidant enzyme activity in cotton callus tissue.

M. Lucas, D. Gossett, E. Millhollon, 1999, Free radical research.

Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.

Johannes C. Hermann, C. Lukacs, A. Kuglstatter, 2014, Journal of medicinal chemistry.

The synthesis of a natural product family: from debromoisolaurinterol to the aplysins

D. Harrowven, M. Lucas, P. Howes, 2001 .

Total syntheses of aplysin and debromoaplysin using a diastereoselective, sulfur mediated radical cyclisation strategy

D. Harrowven, M. Lucas, P. Howes, 1999 .

A simple and direct method for converting thioamides into thioesters

D. Harrowven, M. Lucas, P. Howes, 1999 .

Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors.

Saul Jaime-Figueroa, Sandra Steiner, R. Greenhouse, 2008, Bioorganic & medicinal chemistry letters.

Microwave-enhanced rhodium-catalyzed conjugate-addition of aryl boronic acids to unprotected maleimides

M. Lucas, P. Iyer, Meaghan M. O’Malley, 2007 .

A diastereoselective radical to polar crossover sequence for the synthesis of the isolaurinterols and aplysins

D. Harrowven, M. Lucas, P. Howes, 1999 .

Total Syntheses of Aplysin and Debromoaplysin Using a Diastereoselective, Sulfur Mediated Radical Cyclization Strategy.

D. Harrowven, M. Lucas, P. Howes, 1999 .

A Simple and Direct Method for Converting Thioamides into Thioesters.

D. Harrowven, M. Lucas, P. Howes, 1999 .

The first total synthesis of (±)-1-desoxyhypnophilin

D. Harrowven, M. Lucas, P. Howes, 2001 .

A total synthesis of (±)-1-desoxyhypnophilin: using ring closing metathesis for the construction of cyclic enones

D. Harrowven, M. Lucas, P. Howes, 2000 .

A thiyl radical mediated cascade sequence for the co-cyclisation of 1,6-hexadienes with sulfur atom transfer

D. Harrowven, M. Lucas, P. Howes, 2000 .

Microwave-Enhanced Rhodium-Catalyzed Conjugate-Addition of Aryl Boronic Acids to Unprotected Maleimides.

M. Lucas, P. Iyer, Meaghan M. O’Malley, 2007 .

Antioxidant Response to Salt Stress During Fiber Development in Cotton Ovules

M. Lucas, D. Gossett, E. Millhollon, 1999 .

Discovery of novel PI3-kinase δ specific inhibitors for the treatment of rheumatoid arthritis: taming CYP3A4 time-dependent inhibition.

P. Savy, Steve Price, A. Nadin, 2012, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of new monoamine reuptake inhibitors with potential therapeutic utility in depression and pain.

R. Greenhouse, M. Lucas, S. Lynch, 2010, Bioorganic & medicinal chemistry letters.

A crystalline protein is responsible for dimorphic egg jellies in the spotted salamander, Ambystoma maculatum (Shaw) (Caudata: Ambystomatidae)

M. Lucas, L. Hardy, 1991 .

Effects of N-acetylcysteine on hyperoxic lung in the rat.

M. Lucas, E. Barbero, M. Ludeña, 1995, Respiratory medicine.

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

Johannes C. Hermann, C. Lukacs, Seng-Lai Tan, 2013, Arthritis Research & Therapy.

Small-molecule inhibitors of spleen tyrosine kinase as therapeutic agents for immune disorders: will promise meet expectations?

Seng-Lai Tan, M. Lucas, 2014, Future medicinal chemistry.

2-Substituted N-aryl piperazines as novel triple reuptake inhibitors for the treatment of depression.

R. Roetz, M. Lucas, P. Iyer, 2010, Bioorganic & medicinal chemistry letters.

Current and emerging therapies for Achondroplasia: The dawn of precision medicine.

N. Ishiyama, E. Dardenne, M. Lucas, 2023, Bioorganic & medicinal chemistry.

Palladium-catalyzed, heteroatom assisted, regioselective cyclizations.

M. E. Krafft, M. Lucas, 2003, Chemical communications.

Palladium‐Catalyzed, Heteroatom Assisted, Regioselective Cyclizations.

M. E. Krafft, M. Lucas, 2003 .

Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors.

Amy D. Fung, N. Arora, S. Harris, 2010, Bioorganic & medicinal chemistry letters.

Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors.

Johannes C. Hermann, John Menke, A. Kuglstatter, 2013, Journal of medicinal chemistry.