A. Yokota

发表

Osteoclasts are involved in the maintenance of dormant leukemic cells.

S. Kimura, J. Kuroda, A. Yokota, 2009, Leukemia research.

Isolation of mesenchymal stromal/stem cells from small-volume umbilical cord blood units that do not qualify for the banking system

H. Hirai, A. Takaori-Kondo, T. Ichinohe, 2015, International Journal of Hematology.

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer.

S. Kimura, Motoyoshi Tanaka, J. Kuroda, 2005, The Journal of clinical investigation.

Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes.

M. Caligiuri, N. Salomonis, L. Shih, 2018, Cancer discovery.

Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice.

H. Hirai, A. Yokota, T. Maekawa, 2015, Biochemical and biophysical research communications.

Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models

Y. Hayashi, X. An, J. Cancelas, 2017, Haematologica.

Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL-positive leukemic cells.

S. Kimura, M. Reule, J. Lyons, 2010, Blood.

ABT‐737 is a useful component of combinatory chemotherapies for chronic myeloid leukaemias with diverse drug‐resistance mechanisms

A. Strasser, M. Andreeff, M. Taniwaki, 2007, British journal of haematology.

Constitutively active ABL family kinases, TEL/ABL and TEL/ARG, harbor distinct leukemogenic activities in vivo

H. Hirai, K. Okuda, A. Yokota, 2017, Leukemia.

C/EBP b is a critical mediator of IFN- a – induced exhaustion of chronic myeloid leukemia stem cells

D. Tenen, Y. Hayashi, H. Hirai, 2019 .

system, and cyclosporine A augments its in vivo activity leukemia cells in the central nervous + suppresses the growth of Ph INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor,

S. Kimura, J. Kuroda, S. Masuda, 2010 .

INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity.

S. Kimura, J. Kuroda, S. Masuda, 2007, Blood.

Zoledronate synergises with imatinib mesylate to inhibit Ph+ primary leukaemic cell growth

S. Kimura, J. Kuroda, Y. Fujiyama, 2005, British journal of haematology.

Novel agents to override imatinib resistance mechanisms

S. Kimura, A. Yokota, 2008 .

Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

H. Hirai, A. Andoh, T. Ichinohe, 2017, International Journal of Hematology.

Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma

M. Monden, K. Aozasa, Y. Oji, 2004, Cancer science.

C/EBP b isoforms sequentially regulate regenerating mouse hematopoietic stem/progenitor cells

Y. Hayashi, H. Hirai, A. Yokota, 2020 .

Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer

Y. Miyoshi, S. Noguchi, K. Aozasa, 2003, Cancer science.

Overexpression of the Wilms' tumor gene WT1 in primary astrocytic tumors

Toshiki Yoshimine, Sumiyuki Nishida, Motohiko Maruno, 2004, Cancer science.

Hypoxia/pseudohypoxia‐mediated activation of hypoxia‐inducible factor‐1α in cancer

Y. Hayashi, H. Harada, A. Yokota, 2019, Cancer science.

Cytotoxic effects of γδ T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy

H. Wada, S. Kimura, J. Kuroda, 2005 .

Anti-myeloma effect of homoharringtonine with concomitant targeting of the myeloma-promoting molecules, Mcl-1, XIAP, and β-catenin

M. Andreeff, M. Taniwaki, S. Kimura, 2008, International journal of hematology.

β-Catenin Small Interfering RNA Successfully Suppressed Progression of Multiple Myeloma in a Mouse Model

M. Taniwaki, S. Kimura, J. Kuroda, 2009, Clinical Cancer Research.

A Novel CD135+ Subset of Mouse Monocytes with a Distinct Differentiation Pathway and Antigen-Presenting Properties

H. Hirai, K. Tashiro, M. Nagao, 2022, The Journal of Immunology.

Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia

A. Strasser, M. Andreeff, M. Taniwaki, 2007, Cell Death and Differentiation.

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia.

Tomoko Niwa, Takeshi Yuasa, Eri Kawata, 2005, Blood.

Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment

T. Tsuruo, S. Kimura, J. Kuroda, 2010, Cell Death and Differentiation.

Galectin‐9 ameliorates acute GVH disease through the induction of T‐cell apoptosis

A. Yamauchi, H. Hirai, S. Kimura, 2011, European journal of immunology.

Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer

F. Tanaka, S. Kimura, T. Yoshikawa, 2008, Molecular Cancer Therapeutics.

C/EBPβ is required for survival of Ly6C- monocytes.

D. Tenen, H. Hirai, A. Yokota, 2017, Blood.

C/EBPβ is a critical mediator of IFN-α-induced exhaustion of chronic myeloid leukemia stem cells.

D. Tenen, Y. Hayashi, H. Hirai, 2019, Blood advances.

A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.

H. Hirai, S. Kimura, T. Kiuchi, 2010, Cancer letters.

C/EBPβ isoforms sequentially regulate regenerating mouse hematopoietic stem/progenitor cells.

Y. Hayashi, H. Hirai, A. Yokota, 2020, Blood advances.

Erratum to: Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

H. Hirai, A. Andoh, T. Ichinohe, 2017, International Journal of Hematology.

The early neutrophil-committed progenitors aberrantly differentiate into immunoregulatory monocytes during emergency myelopoiesis.

Y. Hayashi, H. Hirai, Y. Asahina, 2023, Cell reports.

The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies

L. Huo, A. Yokota, Gang Huang, 2020, Molecules and cells.

Multiple myeloma cells adapted to long-exposure of hypoxia exhibit stem cell characters with TGF-β/Smad pathway activation.

Susumu Nakata, H. Hirai, Y. Nakagawa, 2018, Biochemical and biophysical research communications.

AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model

J. Strovel, M. Taniwaki, Y. Hayashi, 2011, Blood cancer journal.

A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo

S. Kimura, A. Yokota, T. Maekawa, 2006, British Journal of Cancer.

Administration of PLK1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer

F. Tanaka, S. Kimura, T. Yoshikawa, 2008 .

Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor

Taira Maekawa, Atsushi Sato, H. Hirai, 2015, Cancer science.

Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.

S. Kimura, J. Kuroda, A. Yokota, 2005, Cancer letters.

Cytotoxic effects of gammadelta T cells expanded ex vivo by a third generation bisphosphonate for cancer immunotherapy.

H. Wada, S. Kimura, J. Kuroda, 2005, International journal of cancer.

The anti-leukemic efficacy of the third generation bisphosphonate ONO5920/YM529.

S. Kimura, J. Kuroda, Y. Fujiyama, 2005, Leukemia research.

Zoledronic acid mediates Ras-independent growth inhibition of prostate cancer cells.

S. Kimura, J. Kuroda, A. Yokota, 2005, Oncology research.

Vitamin K2 Supports Hematopoiesis through Acting on Bone Marrow Mesenchymal Stromal/Stem Cells

H. Hirai, T. Ichinohe, A. Yokota, 2015 .

AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model

J. Strovel, M. Taniwaki, Y. Hayashi, 2011, Blood cancer journal.

Inhibition of Wnt/β-Catenin Signaling by AV65 Treatment Caused Cell Cycle Arrest and Induced Caspase-Independent or -Dependent Apoptosis in CML Cells.

J. Strovel, H. Hirai, S. Kimura, 2009 .

A Novel β-catenin Inhibitor, AV65 Suppresses the Growth of CML Cell Lines Which Acquire Imatinib-Resistance Because of Abl Kinase Domain Mutations Including T315I and Hypoxia-Adaptation.

J. Strovel, S. Kimura, A. Yokota, 2008 .

INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity.

S. Kimura, J. Kuroda, S. Masuda, 2007, Blood.

A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro.

H. Hirai, S. Kimura, T. Kiuchi, 2010, Cancer letters.

A Third-Generation Bisphosphonate, Minodronic Acid (YM529), Augments the Interferon α/β-Mediated Inhibition of Renal Cell Cancer Cell Growth Both In vitro and In vivo

S. Kimura, J. Kuroda, A. Yokota, 2005 .

A third-generation bisphosphonate, minodronic acid (YM529), augments the interferon alpha/beta-mediated inhibition of renal cell cancer cell growth both in vitro and in vivo.

S. Kimura, J. Kuroda, A. Yokota, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.