Won‐Ki Kim

发表

α-Synuclein Activates Microglia by Inducing the Expressions of Matrix Metalloproteinases and the Subsequent Activation of Protease-Activated Receptor-1

Hee-Sun Kim, M. Woo, M. Baek, 2010, The Journal of Immunology.

3‐Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP‐elicited damage both in vivo and in vitro

E. Shin, Hyoung‐Chun Kim, Tongguang Wang, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mimosine prevents the death of glucose‐deprived immunostimulated astrocytes by scavenging peroxynitrite

Y. Oh, Hyoung‐Chun Kim, Won‐Ki Kim, 2002, Glia.

Attenuation of NMDA Receptor Activity and Neurotoxicity by Nitroxyl Anion, NO−

P. V. Rayudu, J. Stamler, S. Lipton, 1999, Neuron.

Dextromethorphan attenuates trimethyltin-induced neurotoxicity via σ1 receptor activation in rats

Seung Woo Shin, S. Nah, T. Nabeshima, 2007, Neurochemistry International.

Metabolism to dextrorphan is not essential for dextromethorphan's anticonvulsant activity against kainate in mice.

G. Bing, E. Shin, Hyoung‐Chun Kim, 2003, Life sciences.

Pretreatment with interferon-gamma protects microglia from oxidative stress via up-regulation of Mn-SOD.

Chunfu Wu, C. Shin, I. Choi, 2009, Free radical biology & medicine.

Intracellular pH-dependent peroxynitrite-evoked synergistic death of glucose-deprived astrocytes.

Hee-Sun Kim, Hyoung‐Chun Kim, B. Han, 2004, Free radical biology & medicine.

Blockade of peroxynitrite-mediated astrocyte death by manganese(III)-cyclam

Hyoung‐Chun Kim, W. Nam, Youngnam N. Jin, 2003, Neurosciences research.

Adenosine and Purine Nucleosides Protect Rat Primary Astrocytes from Peroxynitrite-Potentiated, Glucose Deprivation-Induced Death: Preservation of Intracellular ATP Level

Hyoung‐Chun Kim, C. Shin, Won‐Ki Kim, 2002, Experimental Neurology.

Changes of hippocampal Cu/Zn-superoxide dismutase after kainate treatment in the rat

G. Bing, Hyoung‐Chun Kim, Kanefusa Kato, 2000, Brain Research.

Protection against kainate neurotoxicity by ginsenosides: Attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress

J. Jeong, E. Shin, Hyoung‐Chun Kim, 2009, Journal of neuroscience research.

Aging exacerbates intracerebral hemorrhage-induced brain injury.

Hyoung‐Chun Kim, Won‐Ki Kim, Geum‐Sil Cho, 2009, Journal of neurotrauma.

Glucocorticoids exacerbate peroxynitrite mediated potentiation of glucose deprivation-induced death of rat primary astrocytes

Hyoung‐Chun Kim, C. Shin, Won‐Ki Kim, 2001, Brain Research.

Glucose deprivation decreases nitric oxide production via NADPH depletion in immunostimulated rat primary astrocytes

Hee-Sun Kim, Hyoung‐Chun Kim, C. Shin, 2002, Glia.

Inhibition of MMP‐3 or ‐9 suppresses lipopolysaccharide‐induced expression of proinflammatory cytokines and iNOS in microglia

Hee-Sun Kim, M. Woo, I. Choi, 2008, Journal of neurochemistry.

Intracerebral Hemorrhage-Induced Brain Injury Is Aggravated in Senescence-Accelerated Prone Mice

Hyoung‐Chun Kim, Yong-Sun Kim, Won‐Ki Kim, 2006, Stroke.

Ginsenosides attenuate kainic acid-induced synaptosomal oxidative stress via stimulation of adenosine A2A receptors in rat hippocampus

J. Jeong, E. Shin, Hyoung‐Chun Kim, 2009, Behavioural Brain Research.

Decrease in the kainate-induced wet dog shake behavior in genetically epilepsy-prone rats: possible involvement of an impaired synaptic transmission to the 5-HT(2A) receptor.

J. Jeong, E. Shin, Hyoung‐Chun Kim, 2009, Journal of Pharmacological Sciences.

Degradation of Spectrin via Calpains in the Ventral Horn after Transient Spinal Cord Ischemia in Rabbits

K. Yoo, I. Hwang, M. Won, 2006, Neurochemical Research.

Synergistic expression of inducible nitric oxide synthase by phorbol ester and interferon‐γ is mediated through NF‐κB and ERK in microglial cells

Hee-Sun Kim, Hyoung‐Chun Kim, I. Han, 2003 .

New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice.

J. Jhoo, E. Shin, Hyoung‐Chun Kim, 2003, Life sciences.

The dextromethorphan analog dimemorfan attenuates kainate‐induced seizures via σ1 receptor activation: comparison with the effects of dextromethorphan

S. Nah, E. Shin, Hyoung‐Chun Kim, 2005, British journal of pharmacology.

Synergistic Depletion of Astrocytic Glutathione by Glucose Deprivation and Peroxynitrite

Y. Oh, Hyoung‐Chun Kim, Chan-young Shin, 2000, Journal of neurochemistry.

Protease-Activated Receptor-1 and the Subsequent Activation of Metalloproteinases the Expressions of Matrix -Synuclein Activates Microglia by Inducing a

Hee-Sun Kim, M. Woo, M. Baek, 2010 .

Anti-Inflammatory Mechanisms of Isoflavone Metabolites in Lipopolysaccharide-Stimulated Microglial Cells

J. Hyun, Hee-Sun Kim, M. Woo, 2007, Journal of Pharmacology and Experimental Therapeutics.

A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia

T. Joh, Hee-Sun Kim, M. Woo, 2004, Neuropharmacology.

MAPK Activation Oxide-Dependent Inhibition of JNK and p38 Hemin Toxicity due to Nitric Activated Microglia Are Less Vulnerable to

Woong Sun, Hee-Sun Kim, Won‐Ki Kim, 2011 .

Involvement of N-methyl-d-aspartate receptor and free radical in homocysteine-mediated toxicity on rat cerebellar granule cells in culture

Won‐Ki Kim, Y. Pae, 1996, Neuroscience Letters.

Dehydroepiandrosterone inhibits the death of immunostimulated rat C6 glioma cells deprived of glucose

Hyoung‐Chun Kim, C. Shin, Won‐Ki Kim, 2001, Brain Research.

S-Allyl-l-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase

H. Chun, Won‐Ki Kim, N. Chang, 2006, Free radical research.

Phenidone prevents kainate-induced neurotoxicity via antioxidant mechanisms

G. Bing, E. Shin, Hyoung‐Chun Kim, 2000, Brain Research.

Glucose deprivation increases hydrogen peroxide level in immunostimulated rat primary astrocytes

Hyoung‐Chun Kim, C. Shin, Won‐Ki Kim, 2004, Journal of neuroscience research.

Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase.

C. Shin, Won‐Ki Kim, M. Choi, 2008, Journal of neurotrauma.

Neuroprotective effect of fucoidin on lipopolysaccharide accelerated cerebral ischemic injury through inhibition of cytokine expression and neutrophil infiltration

M. Won, I. Kang, Won‐Ki Kim, 2012, Journal of the Neurological Sciences.

S-nitrosation ameliorates homocysteine-induced neurotoxicity and calcium responses in primary culture of rat cortical neurons

Won‐Ki Kim, 1999, Neuroscience Letters.

Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis.

J. Cheong, C. Shin, K. Son, 2007, European journal of pharmacology.

Anxiolytic-like effects of extracts from Albizzia julibrissin bark in the elevated plus-maze in rats.

B. Lee, J. Cheong, H. Chun, 2004, Life sciences.

Repression of interferon-γ-induced inducible nitric oxide synthase (iNOS) gene expression in microglia by sodium butyrate is mediated through specific inhibition of ERK signaling pathways

Hee-Sun Kim, Won‐Ki Kim, So-Young Kim, 2005, Journal of Neuroimmunology.

Repression of interferon-gamma-induced inducible nitric oxide synthase (iNOS) gene expression in microglia by sodium butyrate is mediated through specific inhibition of ERK signaling pathways.

Hee-Sun Kim, Won‐Ki Kim, So-Young Kim, 2005, Journal of neuroimmunology.

Augmented death in immunostimulated astrocytes deprived of glucose: inhibition by an iron porphyrin FeTMPyP

Hyoung‐Chun Kim, Dong-Hoon Shin, C. Shin, 2001, Journal of Neuroimmunology.

p38 mitogen-activated protein kinase mediates lipopolysaccharide, not interferon-γ, -induced inducible nitric oxide synthase expression in mouse BV2 microglial cells

I. Han, Won‐Ki Kim, J. Ryu, 2002, Neuroscience Letters.

Excretory–secretory products from Paragonimus westermani increase nitric oxide production in microglia in PKC-dependent and -independent manners

I. Choi, Youngnam N. Jin, Won‐Ki Kim, 2009, Neuroscience Research.

Oxidative damage causes formation of lipofuscin-like substances in the hippocampus of the senescence-accelerated mouse after kainate treatment

G. Bing, E. Shin, Hyoung‐Chun Kim, 2002, Behavioural Brain Research.

Simvastatin prevents oxygen and glucose deprivation/reoxygenation‐induced death of cortical neurons by reducing the production and toxicity of 4‐hydroxy‐2E‐nonenal

Hee-Sun Kim, Y. Oh, I. Choi, 2006, Journal of neurochemistry.

Ginseng saponin metabolite suppresses phorbol ester–induced matrix metalloproteinase‐9 expression through inhibition of activator protein‐1 and mitogen‐activated protein kinase signaling pathways in human astroglioma cells

J. Hyun, Hee-Sun Kim, Dong-Hyun Kim, 2006, International journal of cancer.

Role of glutathione peroxidase in the ontogeny of hippocampal oxidative stress and kainate seizure sensitivity in the genetically epilepsy-prone rats

E. Shin, Hyoung‐Chun Kim, Won‐Ki Kim, 2008, Neurochemistry International.

Protection by a manganese porphyrin of endogenous peroxynitrite‐induced death of glial cells via inhibition of mitochondrial transmembrane potential decrease

Hyoung‐Chun Kim, I. Choi, W. Nam, 2000, Glia.

Proliferation-dependent vulnerability of glucose-deprived astrocytes to nitric oxide-induced cytotoxicity

Won‐Ki Kim, Jung-Jin Choi, Jung‐Jin Choi, 1998, Neuroscience Letters.

Excretory-Secretory Products Produced by Paragonimus westermani Differentially Regulate the Nitric Oxide Production and Viability of Microglial Cells

I. Choi, Won‐Ki Kim, Jae‐Chul Lee, 2005, International Archives of Allergy and Immunology.

Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells.

J. Hyun, Hee-Sun Kim, Won‐Ki Kim, 2005, Biochemical and biophysical research communications.

Anti-inflammatory effects of short chain fatty acids in IFN-γ-stimulated RAW 264.7 murine macrophage cells : Involvement of NF-κB and ERK signaling pathways

Hee-Sun Kim, Jin Sun Park, Eun-Jung Lee, 2007 .

Role of oxidative stress in epileptic seizures

J. Jeong, E. Shin, Hyoung‐Chun Kim, 2011, Neurochemistry International.

Effects of dextromethorphan on the seizures induced by kainate and the calcium channel agonist BAY k-8644: comparison with the effects of dextrorphan

E. Shin, Hyoung‐Chun Kim, C. Shin, 2001, Behavioural Brain Research.

Kainate-induced mitochondrial oxidative stress contributes to hippocampal degeneration in senescence-accelerated mice.

J. Jeong, G. Bing, E. Shin, 2008, Cellular signalling.

[27] Redox congeners of nitric oxide, N-methyl-d-aspartate receptors, and Intracellular calcium ion

J. Stamler, S. Lipton, Won‐Ki Kim, 1996 .

Polyphenol amentoflavone affords neuroprotection against neonatal hypoxic‐ischemic brain damage via multiple mechanisms

J. Lee, S. Kang, Dong-Hoon Shin, 2006, Journal of neurochemistry.

Macrophageal/microglial cell activation and cerebral injury induced by excretory–secretory products secreted by Paragonimus westermani

Won‐Ki Kim, J. Kwon, Geum‐Sil Cho, 2006, Neuroscience Research.

Selective modulation of lipopolysaccharide-stimulated cytokine expression and mitogen-activated protein kinase pathways by dibutyryl-cAMP in BV2 microglial cells.

T. Joh, Hee-Sun Kim, P. Jang, 2003, Brain research. Molecular brain research.

Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase

C. Shin, Won‐Ki Kim, J. Ryu, 2006, Neuroscience Research.

Kainate treatment alters TGF-beta3 gene expression in the rat hippocampus.

K. Flanders, Shin-Geon Choi, G. Bing, 2002, Brain research. Molecular brain research.

Prenatal Exposure To Magnetic Field Increases Dopamine Levels In The Striatum Of Offspring

G. Bing, E. Shin, Hyoung‐Chun Kim, 2001, Clinical and experimental pharmacology & physiology.

Effect of repeated seizure experiences on tyrosine hydroxylase immunoreactivities in the brain of genetically epilepsy-prone rats

Hyoung‐Chun Kim, C. Shin, P. Jobe, 2000, Brain Research Bulletin.

Microglial activation and tyrosine hydroxylase immunoreactivity in the substantia nigral region following transient focal ischemia in rats

Youngbuhm Huh, Jong Hoon Ryu, Chan Young Shin, 2003, Neuroscience Letters.

Dimemorfan prevents seizures induced by the L-type calcium channel activator BAY k-8644 in mice

T. Nabeshima, J. Jhoo, E. Shin, 2004, Behavioural Brain Research.

Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: Essential role of astrocyte-derived plasminogen activator inhibitor-1

Chang Soon Choi, L. Ignarro, Kyu Suk Cho, 2011, Neurochemistry International.

N-Methyl-d-aspartate receptor antagonists memantine and MK-801 attenuate the cerebral infarct accelerated by intracorpus callosum injection of lipopolysaccharides

Won‐Ki Kim, C. Ju, Geum‐Sil Cho, 2013, Neuroscience Letters.

Potentiation of N‐methyl‐D‐aspartate‐mediated neurotoxicity by immunostimulated murine microglia

Won‐Ki Kim, K. Ko, 1998, Journal of neuroscience research.

Evidence that protease-activated receptor-2 mediates trypsin-induced reversal of stellation in cultured rat astrocytes

Gyu Hwan Park, Hyoung‐Chun Kim, C. Shin, 2006, Neuroscience Research.

Glial Cell-Specific Regulation of the JC Virus Early Promoter by Histone Deacetylase Inhibitors

J. Henson, Hee-Sun Kim, E. Choi, 2003, Journal of Virology.

Etoposide Reduces Peroxynitrite-Induced Cytotoxicity via Direct Scavenging Effect

I. Choi, Won‐Ki Kim, 2010, Experimental neurobiology.

Nitric oxide-enhanced excitotoxity-independent apoptosis of glucose-deprived neurons

Hyoung‐Chun Kim, Won‐Ki Kim, K. Ko, 1999, Neuroscience Research.

An immunocytochemical study of mitochondrial manganese-superoxide dismutase in the rat hippocampus after kainate administration

Hyoung-Chun Kim, Won-Ki Kim, Kwang Ho Ko, 2000, Neuroscience Letters.

Immunostimulation of rat primary astrocytes decreases intracellular ATP level

Hyoung‐Chun Kim, C. Shin, Won‐Ki Kim, 2001, Brain Research.

IL-6 attenuates trimethyltin-induced cognitive dysfunction via activation of JAK2/STAT3, M1 mAChR and ERK signaling network.

J. Jeong, T. Nabeshima, Kuniaki Saito, 2013, Cellular signalling.

Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging

J. Jeong, S. Nah, T. Nabeshima, 2013, Neuropsychopharmacology.

Antioxidant propolis attenuates kainate-induced neurotoxicity via adenosine A1 receptor modulation in the rat

J. Jhoo, E. Shin, Hyoung‐Chun Kim, 2004, Neuroscience Letters.

PROTECTION AGAINST KAINATE NEUROTOXICITY BY PYRROLIDINE DITHIOCARBAMATE

J. Jhoo, E. Shin, Hyoung‐Chun Kim, 2004, Clinical and experimental pharmacology & physiology.

Role of MAPK/ERK1/2 in the glucose deprivation-induced death in immunostimulated astroglia

Hyoung‐Chun Kim, Won‐Ki Kim, K. Ko, 2005, Neuroscience Letters.

Anti-inflammatory effects of short chain fatty acids in IFN-gamma-stimulated RAW 264.7 murine macrophage cells: involvement of NF-kappaB and ERK signaling pathways.

Hee-Sun Kim, Eun-Jung Lee, Won‐Ki Kim, 2007, International immunopharmacology.

Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice

G. Bing, E. Shin, Hyoung‐Chun Kim, 2012, Journal of Neuroinflammation.

Sodium butyrate suppresses interferon-gamma-, but not lipopolysaccharide-mediated induction of nitric oxide and tumor necrosis factor-alpha in microglia

Hee-Sun Kim, I. Han, Won‐Ki Kim, 2004, Journal of Neuroimmunology.

Platelet-activating factor receptor knockout mice are protected from MPTP-induced dopaminergic degeneration

J. Jeong, T. Nabeshima, Takao Shimizu, 2013, Neurochemistry International.

Transient ischemia-induced changes of excitatory amino acid carrier 1 in the ventral horn of the lumbar spinal cord in rabbits

K. Yoo, I. Hwang, M. Won, 2007, Neurological research.

Lipopolysaccharides-activated human astroglioma cells induce apoptotic death of T-lymphocytes via c-Jun N-terminal kinases-dependent up-regulation of TRAIL

J. Cheong, Won‐Ki Kim, J. Kwon, 2006, Neuroscience Research.

Expression and changes of calbindin D-28k immunoreactivity in the ventral horn after transient spinal cord ischemia in rabbits

I. Hwang, M. Won, T. Kang, 2004, Neuroscience Letters.

Dextromethorphan modulates the AP-1 DNA-binding activity induced by kainic acid

G. Bing, Hyoung‐Chun Kim, Jau-Shyong Hong, 1999, Brain Research.

Very delayed neuronal loss occurs in the glomerular layer of the main olfactory bulb following transient ischemia in gerbils

In Koo Hwang, Ki-Yeon Yoo, K. Yoo, 2004, Neuroscience Letters.

Differential Regulation of Matrix Metalloproteinase-9 and Tissue Plasminogen Activator Activity by the Cyclic-AMP System in Lipopolysaccharide-stimulated Rat Primary Astrocytes

H. Kim, J. Cheong, Jongmin Lee, 2008, Neurochemical Research.

Repeated intracerebroventricular infusion of nicotine prevents kainate-induced neurotoxicity by activating the α7 nicotinic acetylcholine receptor

S. Nah, G. Bing, E. Shin, 2007, Epilepsy Research.

Calbindin D-28k is expressed in the microvascular basal lamina in the ventral horn at early time after transient spinal cord ischemia in the rabbit

K. Yoo, I. Hwang, M. Won, 2005, Brain Research.

Prolonged exposure to cigarette smoke blocks the neurotoxicity induced by kainic acid in rats.

G. Bing, E. Shin, Hyoung‐Chun Kim, 1999, Life sciences.

Mapk Activation Oxide-dependent Inhibition of Jnk and P38 Hemin Toxicity Due to Nitric Activated Microglia Are Less Vulnerable To

Woong Sun, Hee-Sun Kim, Won‐Ki Kim, 2022 .

Protease-activated Receptor-1 and the Subsequent Activation of Metalloproteinases the Expressions of Matrix -synuclein Activates Microglia by Inducing Α

Hee-Sun Kim, M. Baek, I. Choi, 2022 .

Kainate-induced mitochondrial oxidative stress contributes to hippocampal degeneration in senescence-accelerated mice.

J. Jeong, G. Bing, E. Shin, 2008, Cellular signalling.

Is topiramate a potential therapeutic agent for cerebral hypoxic/ischemic injury?

Won‐Ki Kim, J. Choi, 2007, Experimental Neurology.

Intracerebral Hemorrhage-Induced Brain Injury Is Aggravated in Senescence-Accelerated Prone Mice

Hyoung‐Chun Kim, Yong-Sun Kim, Won‐Ki Kim, 2006, Stroke.

Synergistic expression of inducible nitric oxide synthase by phorbol ester and interferon-gamma is mediated through NF-kappaB and ERK in microglial cells.

Hyoung‐Chun Kim, I. Han, E. Joe, 2003, Journal of neuroscience research.