H. Yamaguchi

发表

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice

R. J. Kelleher, Raphael Kopan, E. Giaime, 2010, Proceedings of the National Academy of Sciences.

Early decrease in intermediate monocytes in peripheral blood is characteristic of multiple system atrophy-cerebellar type

J. Kira, R. Yamasaki, N. Isobe, 2020, Journal of Neuroimmunology.

Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study

A. Hiwatashi, J. Kira, T. Fujii, 2017, Journal of Neuroinflammation.

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

H. Cai, E. Giaime, J. Bonventre, 2012, Molecular Neurodegeneration.

Loss of DJ-1 Does Not Affect Mitochondrial Respiration but Increases ROS Production and Mitochondrial Permeability Transition Pore Opening

E. Giaime, Jie Shen, T. Kitada, 2012, PloS one.

MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

M. Ohno, K. Sakumi, M. Furuichi, 2006, Cell Death and Differentiation.

Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis

J. Kira, S. Nagata, R. Yamasaki, 2020, Proceedings of the National Academy of Sciences.

Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model

J. Kira, R. Yamasaki, A. Fujita, 2018, Journal of Neuroinflammation.

Prevention of the Mutagenecity and Cytotoxicity of Oxidized Purine Nucleotides

M. Behmanesh, K. Sakumi, Y. Nakabeppu, 2007 .

Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy

T. Iwaki, J. Kira, R. Yamasaki, 2022, Brain pathology.

A novel model for treatment of hypertrophic pachymeningitis

J. Kira, B. Malissen, M. Kawano, 2019, Annals of clinical and translational neurology.

MTH1, an Oxidized Purine Nucleoside Triphosphatase, Suppresses the Accumulation of Oxidative Damage of Nucleic Acids in the Hippocampal Microglia during Kainate-Induced Excitotoxicity

M. Furuichi, Y. Nakabeppu, D. Kang, 2006, The Journal of Neuroscience.

Potentiation in Hippocampal CA1 Pyramidal Neurons Caffeine-Mediated Presynaptic Long-Term

Eduardo D. Martín, M. White, D. Burks, 2015 .

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons

Jie Shen, F. A. Lai, Bei Wu, 2013, Proceedings of the National Academy of Sciences.

Temporal expression profiling of DAMPs-related genes revealed the biphasic post-ischemic inflammation in the experimental stroke model

M. Mogi, Y. Mori, H. Yamaguchi, 2020, Molecular Brain.

A case of stiff-person syndrome due to secondary adrenal insufficiency.

J. Kira, K. Yamashita, R. Yamasaki, 2017, Rinsho shinkeigaku = Clinical neurology.

Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Mouse Model of Parkinson's Disease

T. Seike, M. Ohno, K. Sakumi, 2009, PloS one.

Oxidative damage in nucleic acids and Parkinson's disease

K. Sakumi, Y. Nakabeppu, H. Yamaguchi, 2007, Journal of neuroscience research.

MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides.

Y. Nakabeppu, H. Yamaguchi, D. Tsuchimoto, 2006, DNA repair.

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

Douglas R. Porter, A. Pisani, P. Bonsi, 2007, Proceedings of the National Academy of Sciences.

Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination

M. Götz, J. Kira, S. Nagata, 2021, Journal of Neuroinflammation.

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice

A. Pisani, E. Pothos, Jie Shen, 2009, Proceedings of the National Academy of Sciences.

Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study

A. Hiwatashi, J. Kira, T. Fujii, 2017, Journal of Neuroinflammation.

Brainstem posterior reversible encephalopathy syndrome in a case with Guillain–Barré syndrome

J. Kira, R. Yamasaki, N. Isobe, 2019, Clinical and Experimental Neuroimmunology.

Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia

J. Kira, R. Yamasaki, N. Isobe, 2018, Front. Immunol..

Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior

J. Kira, Koichiro Matsumoto, R. Yamasaki, 2021, Brain, Behavior, and Immunity.

Histological analysis of neurodegeneration in the mouse brain.

Jie Shen, H. Yamaguchi, 2013, Methods in molecular biology.

HLA-DRB1*04:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis

A. Hiwatashi, O. Togao, J. Kira, 2018, Multiple sclerosis.

Cerebral blood flow laterality derived from arterial spin labeling as a biomarker for assessing the disease severity of parkinson's disease

K. Yamashita, A. Hiwatashi, O. Togao, 2017, Journal of magnetic resonance imaging : JMRI.

Multimodal diagnostic approach for limbic encephalitis associated with antivoltage‐gated potassium channel complex antibodies

H. Shigeto, J. Kira, T. Uehara, 2015 .

Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice

Jie Shen, H. Yamaguchi, 2007, Molecular Neurodegeneration.

Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model

J. Kira, R. Yamasaki, A. Fujita, 2018, Journal of Neuroinflammation.

Structural changes in Parkinson’s disease: voxel-based morphometry and diffusion tensor imaging analyses based on 123I-MIBG uptake

S. Baba, K. Yamashita, A. Hiwatashi, 2017, European Radiology.

[A case of rhabdomyolysis after status epilepticus without stroke-like episodes in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes].

H. Shigeto, J. Kira, T. Uchiumi, 2016, Rinsho shinkeigaku = Clinical neurology.

A case of rhabdomyolysis after status epilepticus without stroke-like episodes in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.

H. Shigeto, J. Kira, T. Uchiumi, 2017, Rinsho shinkeigaku = Clinical neurology.

Dermatomyositis complicated with asymmetric peripheral neuritis on exacerbation: A case report and literature review

H. Shigeto, J. Kira, T. Irie, 2016 .

A case of multiple system atrophy-parkinsonian type with stuttering- and palilalia-like dysfluencies and putaminal atrophy.

K. Yamashita, A. Hiwatashi, J. Kira, 2017, Journal of fluency disorders.

Iguratimod Ameliorates the Severity of Secondary Progressive Multiple Sclerosis in Model Mice by Directly Inhibiting IL-6 Production and Th17 Cell Migration via Mitigation of Glial Inflammation

R. Yamasaki, N. Isobe, H. Yamaguchi, 2023, Biology.

Peripheral blood T cell subset characteristics of multiple sclerosis in remission phase correlate with annualized relapse rates

J. Kira, R. Yamasaki, H. Yamaguchi, 2016 .

Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model

N. Isobe, H. Yamaguchi, K. Masaki, 2024, Scientific reports.