M. Amar

发表

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells.

A. Remaley, R. Youle, Robert J. Huang, 2011, The Journal of clinical investigation.

Apolipoprotein C-II: New findings related to genetics, biochemistry, and role in triglyceride metabolism.

A. Remaley, L. Freeman, A. Wolska, 2017, Atherosclerosis.

Lecithin: cholesterol acyltransferase--from biochemistry to role in cardiovascular disease.

A. Remaley, M. Amar, A. Sethi, 2009, Current opinion in endocrinology, diabetes, and obesity.

Cholesteryl Ester Transfer Protein Corrects Dysfunctional High Density Lipoproteins and Reduces Aortic Atherosclerosis in Lecithin Cholesterol Acyltransferase Transgenic Mice*

R. F. Hoyt, H. Brewer, R. Shamburek, 1999, The Journal of Biological Chemistry.

Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo

A. Remaley, T. Eggerman, R. Star, 2017, PloS one.

Class B Scavenger Receptor Types I and II and CD36 Targeting Improves Sepsis Survival and Acute Outcomes in Mice

A. Remaley, T. Eggerman, R. Star, 2012, The Journal of Immunology.

Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited Published, JLR Papers in Press, October 23, 2006.

B. Brewer, H. Brewer, R. Shamburek, 2007, Journal of Lipid Research.

Hepatic ABCG5 and ABCG8 Overexpression Increases Hepatobiliary Sterol Transport but Does Not Alter Aortic Atherosclerosis in Transgenic Mice*

G. Szakács, H. Brewer, R. Shamburek, 2004, Journal of Biological Chemistry.

Effects of FXR in foam-cell formation and atherosclerosis development.

B. Brewer, F. Gonzalez, B. Paigen, 2006, Biochimica et biophysica acta.

ABCA1 Overexpression in the Liver of LDLr-KO Mice Leads to Accumulation of Pro-atherogenic Lipoproteins and Enhanced Atherosclerosis*

H. Brewer, R. Shamburek, A. Remaley, 2006, Journal of Biological Chemistry.

Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein.

R. F. Hoyt, H. Brewer, R. Shamburek, 2009, Metabolism: clinical and experimental.

Role of Lecithin

R. Shamburek, A. Remaley, L. Freeman, 2014 .

A new phenotypic classification system for dyslipidemias based on the standard lipid panel

R. Shamburek, A. Remaley, R. Rosenson, 2021, Lipids in health and disease.

Complex association of apolipoprotein E–containing HDL with coronary artery disease burden in cardiovascular disease

A. Remaley, N. Mehta, Marcus Y. Chen, 2022, JCI insight.

Low ambient oxygen prevents atherosclerosis

Jichun Chen, P. M. Hwang, A. Remaley, 2016, Journal of Molecular Medicine.

Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia

A. Remaley, J. Witztum, Longhou Fang, 2015, Disease Models & Mechanisms.

Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue

A. Remaley, V. Manganiello, F. Ahmad, 2016, Scientific Reports.

A New Equation for Calculation of Low-Density Lipoprotein Cholesterol in Patients With Normolipidemia and/or Hypertriglyceridemia.

A. Jaffe, R. Shamburek, A. Remaley, 2020, JAMA cardiology.

Supplementation with saury oil, a fish oil high in omega-11 monounsaturated fatty acids, improves plasma lipids in healthy subjects.

J. Troendle, R. Shamburek, A. Remaley, 2019, Journal of clinical lipidology.

Apolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents.

D. Sviridov, A. Remaley, D. Osei-Hwedieh, 2011, Pharmacology & therapeutics.

The role of hepatic lipase in lipoprotein metabolism and atherosclerosis.

C. Haudenschild, K. Dugi, M. Amar, 1999, Current opinion in lipidology.

A new phenotypic classification system for dyslipidemias based on the standard lipid panel

P. Wilson, R. Shamburek, A. Remaley, 2021, Lipids in health and disease.

Familial lecithin:cholesterol acyltransferase deficiency: First-in-human treatment with enzyme replacement.

R. Shamburek, A. Remaley, L. Freeman, 2016, Journal of clinical lipidology.

A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides

R. Pastor, Soumitra S Ghosh, S. Neher, 2020, Science Translational Medicine.

The role of hepatic lipase in lipoprotein metabolism and atherosclerosis

M. Amar, S. Santamarina-Fojo, Changting Haudenschild, 1998 .

Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells Published, JLR Papers in Press, March 1, 2005. DOI 10.1194/jlr.M400396-JLR200

N. Seidah, M. Krempf, H. Brewer, 2005, Journal of Lipid Research.

Scavenger receptor-BI is a receptor for lipoprotein(a)

L. Becker, A. Remaley, L. Freeman, 2013, Journal of Lipid Research.

Apolipoprotein C-II Mimetic Peptide Promotes the Plasma Clearance of Triglyceride-Rich Lipid Emulsion and the Incorporation of Fatty Acids into Peripheral Tissues of Mice

A. Remaley, T. Sakurai, A. Wolska, 2019, Journal of nutrition and metabolism.

Asymmetry in the Lipid Affinity of Bihelical Amphipathic Peptides

D. Sviridov, H. Brewer, A. Remaley, 2008, Journal of Biological Chemistry.

Enhanced ABCG1 expression increases atherosclerosis in LDLr-KO mice on a western diet.

A. Remaley, B. Paigen, M. Amar, 2006, Biochemical and biophysical research communications.

A Novel Apolipoprotein C-II Mimetic Peptide That Activates Lipoprotein Lipase and Decreases Serum Triglycerides in Apolipoprotein E–Knockout Mice

A. Remaley, T. Sakurai, L. Freeman, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Mite-induced Asthma Attenuates the Induction of House Dust 5a, an Apolipoprotein A-i Mimetic Peptide

J. McCoy, S. Levine, M. Amar, 2022 .

Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice

A. Remaley, T. Eggerman, Chengyu Liu, 2015, BioMed research international.

Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo.

H. Brewer, R. Shamburek, B. Föger, 2000, Journal of lipid research.

Hepatic lipase facilitates the selective uptake of cholesteryl esters from remnant lipoproteins in apoE-deficient mice.

R. F. Hoyt, H. Brewer, R. Shamburek, 1998, Journal of lipid research.

Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations Published, JLR Papers in Press, November 4, 2002. DOI 10.1194/jlr.M200414-JLR200

H. Brewer, A. Remaley, T. Tansey, 2003, Journal of Lipid Research.

Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mices⃞ Published, JLR Papers in Press, October 27, 2006.

H. Brewer, R. Shamburek, B. Paigen, 2007, Journal of Lipid Research.

The Ligand-binding Function of Hepatic Lipase Modulates the Development of Atherosclerosis in Transgenic Mice*

H. Brewer, R. Shamburek, B. Paigen, 2004, Journal of Biological Chemistry.

Apolipoprotein Mimetic Peptides: Potential New Therapies for Cardiovascular Diseases

A. Remaley, A. Wolska, M. Amar, 2021, Cells.

SR-BI mediates neutral lipid sorting from LDL to lipid droplets and facilitates their formation

A. Remaley, T. Eggerman, S. K. Drake, 2020, PloS one.

Sphingosine 1-Phosphate Lyase Deficiency Disrupts Lipid Homeostasis in Liver*

R. Proia, A. Remaley, B. Lee, 2010, The Journal of Biological Chemistry.

Erratum to: Randomized double blind clinical trial on the effect of oral α-cyclodextrin on serum lipids

R. Shamburek, A. Remaley, A. Courville, 2017, Lipids in Health and Disease.

Randomized double blind clinical trial on the effect of oral α-cyclodextrin on serum lipids

R. Shamburek, A. Remaley, A. Courville, 2016, Lipids in Health and Disease.

Comparison of Omega-3 Eicosapentaenoic Acid Versus Docosahexaenoic Acid-Rich Fish Oil Supplementation on Plasma Lipids and Lipoproteins in Normolipidemic Adults

A. Remaley, N. Mehta, A. Courville, 2020, Nutrients.

Estimated Atherosclerotic Cardiovascular Disease Risk Score: An Automated Decision Aid for Statin Therapy.

A. Remaley, A. Wolska, M. Sampson, 2022, Clinical chemistry.

Dietary Palmitoleic Acid Attenuates Atherosclerosis Progression and Hyperlipidemia in Low-Density Lipoprotein Receptor-Deficient Mice.

A. Remaley, Kwame Donkor, M. Sampson, 2019, Molecular nutrition & food research.

Safety and Tolerability of ACP-501, a Recombinant Human Lecithin:Cholesterol Acyltransferase, in a Phase 1 Single-Dose Escalation Study.

R. Shamburek, A. Remaley, L. Freeman, 2016, Circulation research.

LCAT protects against Lipoprotein‐X formation in a murine model of drug‐induced intrahepatic cholestasis

A. Remaley, S. Karathanasis, L. Freeman, 2019, Pharmacology research & perspectives.

Intravenous toxicity and toxicokinetics of an HDL mimetic, Fx‐5A peptide complex, in cynomolgus monkeys

A. Remaley, M. Bourdi, M. Amar, 2018, Regulatory toxicology and pharmacology : RTP.

This information is current as Mite-Induced Asthma Attenuates the Induction of House Dust 5 A , an Apolipoprotein A-I Mimetic Peptide , Remaley and

J. McCoy, S. Levine, M. Amar, 2010 .

Dietary Intake Patterns Are Consistent Across Seasons in a Cohort of Healthy Adults in a Metropolitan Population.

A. Courville, M. Amar, Rachel C. Kelley, 2016, Journal of the Academy of Nutrition and Dietetics.

Apolipoprotein AI mimetic peptides: possible new agents for the treatment of atherosclerosis.

R. Shamburek, A. Remaley, M. Amar, 2007, Current opinion in investigational drugs.

Lecithin Cholesterol Acyltransferase: An Anti- or Pro-atherogenic Factor?

R. Shamburek, A. Remaley, M. Amar, 2011, Current atherosclerosis reports.

A cholesterol-lowering VLP vaccine that targets PCSK9.

A. Remaley, J. Schiller, B. Chackerian, 2015, Vaccine.

Effect of niacin monotherapy on high density lipoprotein composition and function

A. Remaley, N. Mehta, T. Vaisar, 2020, Lipids in Health and Disease.

Fluorescent pegylated nanoparticles demonstrate fluid-phase pinocytosis by macrophages in mouse atherosclerotic lesions.

H. Kruth, M. Amar, Chiara Buono, 2009, The Journal of clinical investigation.

Intranasal Delivery of E-Selectin Reduces Atherosclerosis in ApoE−/− Mice

A. Elkahloun, A. Remaley, J. Hallenbeck, 2011, PloS one.

The Farnesoid X-receptor Is an Essential Regulator of Cholesterol Homeostasis*

Grace Guo, H. Brewer, F. Gonzalez, 2003, The Journal of Biological Chemistry.

5A, an Apolipoprotein A-I Mimetic Peptide, Attenuates the Induction of House Dust Mite-Induced Asthma

P. Dagur, J. McCoy, A. Remaley, 2011, The Journal of Immunology.

Randomized double blind clinical trial on the effect of oral α-cyclodextrin on serum lipids

R. Shamburek, A. Remaley, A. Courville, 2016, Lipids in Health and Disease.

Zinc Finger Protein Tristetraprolin Interacts with CCL3 mRNA and Regulates Tissue Inflammation

P. Blackshear, A. Remaley, Ping-yuan Wang, 2011, The Journal of Immunology.

Inflammationwith CCL3 mRNA and Regulates Tissue Zinc Finger Protein Tristetraprolin Interacts

P. Blackshear, A. Remaley, Ping-yuan Wang, 2011 .

Creation of Apolipoprotein C-II (ApoC-II) Mutant Mice and Correction of Their Hypertriglyceridemia with an ApoC-II Mimetic Peptide

A. Remaley, Chengyu Liu, Ling Yang, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Low ambient oxygen prevents atherosclerosis

Jichun Chen, A. Remaley, Ping-yuan Wang, 2016, Journal of Molecular Medicine.

Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo.

M. Garcia-Blanco, B. Brewer, A. Remaley, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

R. F. Hoyt, H. Brewer, A. Remaley, 2001, Proceedings of the National Academy of Sciences of the United States of America.

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice.

H. Brewer, R. Shamburek, A. Remaley, 2001, The Journal of clinical investigation.

HDL-replacement therapy: mechanism of action, types of agents and potential clinical indications

D. Sviridov, A. Remaley, M. Amar, 2008, Expert review of cardiovascular therapy.

Abstract 18091: Role of Endothelial Expression of ABCA1 and SR-BI Genes in HDL Metabolism, Cholesterol Trafficking and Protection Against Atherosclerosis.

A. Remaley, M. Sampson, M. Amar, 2010 .

Lcat overexpression in different animal models: modulation of atherosclerosis by CETP, HL and apoA-1

H. Brewer, J. Hoeg, C. Koch, 1999 .

Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.

R. Shamburek, A. Remaley, E. Wasmuth, 2008, Human molecular genetics.

Dietary α-cyclodextrin reduces atherosclerosis and modifies gut flora in apolipoprotein E-deficient mice.

A. Remaley, Jun Zhu, T. Sakurai, 2017, Molecular nutrition & food research.

Apolipoprotein E negatively regulates house dust mite-induced asthma via a low-density lipoprotein receptor-mediated pathway.

N. Raghavachari, A. Remaley, S. Levine, 2010, American journal of respiratory and critical care medicine.

The E-box motif in the proximal ABCA1 promoter mediates transcriptional repression of the ABCA1 gene.

H. Brewer, A. Remaley, L. Freeman, 2002, Journal of lipid research.

Human SR-BI and SR-BII Potentiate Lipopolysaccharide-Induced Inflammation and Acute Liver and Kidney Injury in Mice

A. Remaley, T. Eggerman, R. Star, 2016, The Journal of Immunology.

This information is current as and Acute Liver and Kidney Injury in Mice Lipopolysaccharide-Induced Inflammation Human SR-BI and SR-BII Potentiate Star and

T. Eggerman, P. S. Yuen, Xuzhen Hu, 2016 .

Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice.

R. F. Hoyt, B. Paigen, Z. Nong, 2003, The Journal of clinical investigation.

Contribution of Macromolecular Structure to the Retention of Low-Density Lipoprotein at Arterial Branch Points

R. Balaban, A. Remaley, J. L. Schroeder, 2008, Circulation.

5A Apolipoprotein Mimetic Peptide Promotes Cholesterol Efflux and Reduces Atherosclerosis in Mice

D. Sviridov, A. Remaley, M. Amar, 2010, Journal of Pharmacology and Experimental Therapeutics.

Apolipoprotein E Negatively Regulates House Dust Mite-induced Asthma via a LDL Receptor-mediated Pathway

N. Raghavachari, A. Remaley, S. Levine, 2010 .

A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency With Severe Triglyceridemia and Pancreatitis

D. Rader, R. Hegele, R. Shamburek, 2017, The Journal of clinical endocrinology and metabolism.

The Role of the Novel Lipokine Palmitoleic Acid in Cardiovascular Health: from Bench to Bedside*

A. Remaley, M. Sampson, M. Amar, 2019, Journal of Clinical Lipidology.

In vivo evidence for both lipolytic and nonlipolytic function of hepatic lipase in the metabolism of HDL.

R. F. Hoyt, H. Brewer, R. Shamburek, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Approach to the Patient with a Suboptimal Statin Response: Causes and Algorithm for Clinical Management.

A. Remaley, A. Wolska, M. Amar, 2023, The Journal of clinical endocrinology and metabolism.

Hydrophobic Amino Acids in the Hinge Region of the 5A Apolipoprotein Mimetic Peptide are Essential for Promoting Cholesterol Efflux by the ABCA1 Transporter

I. Anishchenko, A. Remaley, S. Turner, 2013, The Journal of Pharmacology and Experimental Therapeutics.

A VACCINE-BASED STRATEGY FOR REDUCING CARDIOVASCULAR DISEASE RISK FACTORS

A. Remaley, I. Lindquist, B. Chackerian, 2017 .