B. Miller

发表

Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.

S. Orkin, O. Platt, G. P. Beardsley, 1984, The Journal of clinical investigation.

Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia.

D. Faller, E. Vichinsky, T. Papayannopoulou, 1989, Blood.

A minimal cytoplasmic subdomain of the erythropoietin receptor mediates p70 S6 kinase phosphorylation.

M. H. Nguyen, B. Beattie, D. Barber, 2001, Experimental hematology.

Molecular Mechanisms of Erythropoietin Signaling

J. Cheung, B. Miller, 2001, Nephron.

Identification of the Erythropoietin Receptor Domain Required for Calcium Channel Activation*

B. Beattie, D. Barber, J. Cheung, 1999, The Journal of Biological Chemistry.

Bcl-3 expression and nuclear translocation are induced by granulocyte-macrophage colony-stimulating factor and erythropoietin in proliferating human erythroid precursors.

E. Harhaj, S. Sun, B. Miller, 1998, Blood.

Identification of an N-terminal TRPC2 splice variant which inhibits calcium influx.

J. Cheung, D. Barber, R. Stahl, 2005, Cell calcium.

Interaction of TRPC2 and TRPC6 in Erythropoietin Modulation of Calcium Influx*

J. Cheung, D. Barber, R. Stahl, 2004, Journal of Biological Chemistry.

A Novel TRPM2 Isoform Inhibits Calcium Influx and Susceptibility to Cell Death*

J. Cheung, B. Miller, X. Chu, 2003, The Journal of Biological Chemistry.

Expression of SCL is normal in transfusion-dependent Diamond-Blackfan anemia but other bHLH proteins are deficient.

C. Begley, N. Olivieri, G. Clawson, 1997, Blood.

Regulation of the Transient Receptor Potential Channel TRPM2 by the Ca2+ Sensor Calmodulin*

J. Cheung, B. Z. Peterson, B. Miller, 2006, Journal of Biological Chemistry.

Three-dimensional intracellular calcium gradients in single human burst-forming units-erythroid-derived erythroblasts induced by erythropoietin.

D. Tillotson, B. Miller, R. Scaduto, 1990, The Journal of clinical investigation.

Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma

Hong-Gang Wang, B. Miller, Neema Bhat, 2018, Molecular Cancer Therapeutics.

Expression Patterns of Immune Genes Reveal Heterogeneous Subtypes of High-Risk Neuroblastoma

Zhenqiu Liu, Hong-Gang Wang, V. Spiegelman, 2020, Cancers.

TRPM2 Channels Protect against Cardiac Ischemia-Reperfusion Injury

S. Merali, Xueqian Zhang, J. Cheung, 2014, The Journal of Biological Chemistry.

The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2

J. Cheung, Hong-Gang Wang, Shu-Jen Chen, 2019, Scientific Reports.

TRPM2 in Cancer.

B. Miller, 2019, Cell calcium.

A Splice Variant of the Human Ion Channel TRPM2 Modulates Neuroblastoma Tumor Growth through Hypoxia-inducible Factor (HIF)-1/2α*

T. Abraham, Y. Kawasawa, S. Merali, 2014, The Journal of Biological Chemistry.

Transient Receptor Potential-Melastatin Channel Family Member 2: Friend or Foe.

J. Cheung, B. Miller, 2017, Transactions of the American Clinical and Climatological Association.

Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance.

Xueqian Zhang, J. Cheung, W. Koch, 2015, American journal of physiology. Heart and circulatory physiology.

TRPM2ChannelsProtectagainstCardiacIschemia-Reperfusion InjuryIA *□S

S. Merali, Xueqian Zhang, J. Cheung, 2014 .

LUCA-15 suppresses CD95-mediated apoptosis in Jurkat T cells

M. Lerman, Gwyn T. Williams, L. Sutherland, 2001, Oncogene.

Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.

B. Miller, L. Bell, J. Cheung, 1994, Cell calcium.

EXPRESSION OF ANGIOTENSIN II TYPE I RECEPTOR ON ERYTHROID PROGENITORS OF PATIENTS WITH POST TRANSPLANT ERYTHROCYTOSIS1

J. Cheung, B. Miller, N. Ahsan, 2000, Transplantation.

Effects of alcohol feeding on synthesis and secretion of apolipoproteins by regenerating rat sciatic nerve.

R. C. Lin, S. Ochs, L. Lumeng, 1992, Alcoholism, clinical and experimental research.

Thy‐1 is a differentiation antigen that characterizes immature murine erythroid and myeloid hematopoietic progenitors

D. Linch, J. Lipton, S. Burakoff, 1985, Journal of cellular physiology.

TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1.

M. Love, W. B. Reeves, B. Miller, 2014, The Journal of clinical investigation.

TRPM 2 mediates ischemic kidney injury and oxidant stress through RAC 1

M. Love, W. B. Reeves, B. Miller, 2022 .

Effect of chronic alcohol ingestion on the binding of high density lipoproteins to rat hepatic membranes: involvement of apolipoprotein E.

R. C. Lin, B. Miller, 1992, Alcoholism, clinical and experimental research.

TRPM2 Ca 2 (cid:1) channel regulates energy balance and glucose metabolism

R. Friedline, Jason K. Kim, D. Jung, 2012 .

TRPM 2 Ca 2 channel regulates energy balance and glucose metabolism

R. Friedline, F. Kim, Eunjung Lee, 2012 .

TRPM2 Ca2+ channel regulates energy balance and glucose metabolism.

R. Friedline, F. Kim, Eunjung Lee, 2012, American journal of physiology. Endocrinology and metabolism.

NF-κB Transcription Factors Are Involved in Normal Erythropoiesis

Shao-Cong Sun, Min Zhang, B. Miller, 1998 .

Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy

S. Merali, Xueqian Zhang, J. Cheung, 2020, Cell Death & Disease.

Trpm2 enhances physiological bioenergetics and protects against pathological oxidative cardiac injury: Role of Pyk2 phosphorylation

Xueqian Zhang, J. Cheung, M. Madesh, 2019, Journal of cellular physiology.

TRPM2 protects against tissue damage following oxidative stress and ischaemia–reperfusion

J. Cheung, B. Miller, 2016, The Journal of physiology.

NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx.

G. Dubyak, B. Miller, H. M. Russo, 2016, American journal of physiology. Cell physiology.

and influx 2 + efflux and Ca + disruption : roles for K lysosome disruption but inhibited by extensive lysosome NLRP 3 inflammasome signaling

G. Dubyak, B. Miller, H. M. Russo, 2016 .

Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage.

J. Buckwalter, J. Martin, James A. Martin, 2002, Osteoarthritis and cartilage.

Detection of staphylococcal enterotoxins A, B, C, D, and E in foods by radioimnunoassay, using staphyloccal cells containing protein A as immunoadsorbent

M. Bergdoll, R. Reiser, B. Miller, 1978, Applied and environmental microbiology.

Ca 2 (cid:2) entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance MAMMALIAN CELLS

Xueqian Zhang, J. Cheung, W. Koch, 2015 .

Deficiency of alpha-spectrin synthesis in burst-forming units-erythroid in lethal hereditary spherocytosis

C. F. Whitfield, B. Miller, L. Lopresti-Morrow, 1991 .

Deficiency of alpha-spectrin synthesis in burst-forming units-erythroid in lethal hereditary spherocytosis.

C. F. Whitfield, B. Miller, L. Lopresti-Morrow, 1991, Blood.

Rapid Publication Hydroxyurea Enhances Fetal Hemoglobin Production in Sickle Cell Anemia

S. Orkin, G. P. Beardsley, D. Nathan, 2013 .

The human homologue of the Aspergillus nuclear migration gene nudC is preferentially expressed in dividing cells and ciliated epithelia

S. Osmani, C. Gocke, B. Miller, 2000, Histochemistry and Cell Biology.

A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis.

C. Lynch, S. Osmani, A. Osmani, 1999, Experimental hematology.

Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia.

S. Orkin, N. Olivieri, D. Nathan, 1987, The New England journal of medicine.

TRPC3 Activation by Erythropoietin Is Modulated by TRPC6*

J. Cheung, A. Barber, D. Barber, 2009, Journal of Biological Chemistry.

Analysis of hemoglobin F production in Saudi Arabian families with sickle cell anemia.

S. Orkin, N. Olivieri, D. Nathan, 1987, Blood.

Saudi Arabian Sickle Cell Anemia a

S. Orkin, N. Olivieri, D. Nathan, 1989, Annals of the New York Academy of Sciences.

NF-kappaB transcription factors are involved in normal erythropoiesis.

S. Sun, Shao-Cong Sun, B. Miller, 1998, Blood.

Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma.

B. Beattie, D. Barber, B. Miller, 2005, Experimental cell research.

The effect of natural killer cells on the development of syngeneic hematopoietic progenitors.

B. Miller, L. Holmberg, K. Ault, 1984, Journal of immunology.

Effect of glucagon on hepatic taurocholate uptake: relationship to membrane potential.

L. Lumeng, B. Miller, J. Edmondson, 1985, The American journal of physiology.

Mechanisms of Erythropoietin Signal Transduction: Involvement of Calcium Channels

J. Cheung, B. Miller, 1994, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Involvement of the fungal nuclear migration gene nudC human homolog in cell proliferation and mitotic spindle formation.

M. Razzaque, G. Clawson, S. Osmani, 2002, Experimental cell research.

Erythropoietin-modulated calcium inﬂux through TRPC2 is mediated by phospholipase C (cid:1) and IP 3 R

J. Cheung, D. Barber, R. Stahl, 2004 .

Glucocorticoids enhance the anti-leukemic activity of FLT3 inhibitors in FLT3 mutant acute myeloid leukemia.

Zhongming Zhao, Zhenqiu Liu, Hong-Gang Wang, 2020, Blood.

proteins in the response of erythroblasts to erythropoietin Role of pertussis toxin-sensitive guanosine triphosphate-binding

C. F. Whitfield, B. Miller, K. Foster, 2011 .

LUCA-15-encoded sequence variants regulate CD95-mediated apoptosis

C. Cooper, Gwyn T. Williams, L. Sutherland, 2000, Oncogene.

G-Protein a Subunit Gi a 2 Mediates Erythropoietin Signal Transduction in Human Erythroid Precursors

J. Cheung, C. Hansen, M. Linder, 2013 .

G-protein alpha subunit Gi(alpha)2 mediates erythropoietin signal transduction in human erythroid precursors.

C. Hansen, M. Linder, B. Miller, 1996, The Journal of clinical investigation.

Interferon-γ Modulates Fetal Hemoglobin Synthesis in Sickle Cell Anemia and Thalassemia

D. Faller, N. Olivieri, S. Perrine, 1990 .

Steel factor affects SCL expression during normal erythroid differentiation.

J. Cheung, C. Begley, D. Wojchowski, 1994, Blood.

Influence of Acetate Buffers and Metal Ions on Ketonization Rates of Enolpyruvate: A Further Test of the Marcus Function.

B. Miller, D. Leussing, 1985 .

Detection of leukemia-related karyotypes in granulocyte/macrophage colonies from a patient with acute myelomonocytic leukemia.

J. Lipton, D. Nathan, H. Weinstein, 1983, The New England journal of medicine.

Identification of cell surface antigens present on murine hematopoietic stem cells.

T. Springer, B. Miller, G. Antognetti, 1985, Journal of immunology.

Ion channels in human erythroblasts. Modulation by erythropoietin.

D. Tillotson, B. Miller, U. Brauneis, 1992, The Journal of clinical investigation.

High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined.

S. Orkin, D. Weatherall, D. Nathan, 1986, Blood.

Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis.

K. McIntyre, N. Letvin, G. P. Beardsley, 1985, The Journal of clinical investigation.

High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined

S. Orkin, D. Weatherall, D. Nathan, 1986 .

Influence of hydroxyurea on fetal hemoglobin production in vitro.

O. Platt, D. Nathan, G. Dover, 1987, Blood.

Influence of steel factor on hemoglobin synthesis in sickle cell disease.

D. Williams, A. Bernstein, N. Olivieri, 1992, Blood.

Gamma-interferon alters globin gene expression in neonatal and adult erythroid cells.

D. Faller, S. Perrine, S. Emerson, 1987, Blood.

Determination of the hemoglobin F program in human progenitor-derived erythroid cells.

D. Linch, J. Lipton, D. Nathan, 1985, The Journal of clinical investigation.

erythroid cells Gamma-interferon alters globin gene expression in neonatal and adult

D. Faller, S. Perrine, S. Emerson, 2011 .

Analysis of Hemoglobin F Production in Saudi Arabian Families With Sickle Cell Anemia

S. Orkin, N. Olivieri, D. Nathan, 1987 .

Hydroxyurea increases fetal hemoglobin production in sickle cell anemia.

S. Orkin, O. Platt, G. P. Beardsley, 1984, Transactions of the Association of American Physicians.

Granulocyte-macrophage colony-stimulating factor reactivates fetal hemoglobin synthesis in erythroblast clones from normal adults.

U. Testa, E. Tritarelli, C. Labbaye, 1989, Blood.

MB-02 cells undergo fetal to adult globin gene switching in response to erythropoietin.

S. Perrine, D. Morgan, B. Miller, 1989, Biochemical and biophysical research communications.

Erythropoietin stimulates a rise in intracellular free calcium concentration in single early human erythroid precursors.

D. Tillotson, B. Miller, R. Scaduto, 1988, The Journal of clinical investigation.

Butryic acid analogues augment γ globin gene expression in neonatal erythroid progenitors

D. Faller, S. Perrine, B. Miller, 1987 .

Production in Sickle Cell Anemia

S. Orkin, G. P. Beardsley, D. Nathan, 1984 .

Trpc2 depletion protects red blood cells from oxidative stress-induced hemolysis.

J. Cheung, Shu-Jen Chen, I. Hirschler-Laszkiewicz, 2012, Experimental hematology.

The Transient Receptor Potential (TRP) Channel TRPC3 TRP Domain and AMP-activated Protein Kinase Binding Site Are Required for TRPC3 Activation by Erythropoietin*

J. Cheung, Shu-Jen Chen, I. Hirschler-Laszkiewicz, 2011, The Journal of Biological Chemistry.

TRPC3 Is the Erythropoietin-regulated Calcium Channel in Human Erythroid Cells*

J. Cheung, D. Barber, I. Hirschler-Laszkiewicz, 2008, Journal of Biological Chemistry.

Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R.

J. Cheung, D. Barber, R. Stahl, 2004, American journal of physiology. Cell physiology.

Erythropoietin Modulates Calcium Influx through TRPC2*

J. Cheung, D. Carey, L. Birnbaumer, 2002, The Journal of Biological Chemistry.

Modulation of calcium channels in human erythroblasts by erythropoietin.

D. Tillotson, K. Bokvist, B. Miller, 1997, Blood.

Role of pertussis toxin-sensitive guanosine triphosphate-binding proteins in the response of erythroblasts to erythropoietin.

C. F. Whitfield, B. Miller, J. Robishaw, 1991, Blood.

Stopping the Biologic Clock for Globin Gene Switching a

Y. Kan, D. Faller, A. Sytkowski, 1990, Annals of the New York Academy of Sciences.

Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics*

Joseph Y. Cheung, Thomas Abraham, Barbara A. Miller, 2016, The Journal of Biological Chemistry.

The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation

Xueqian Zhang, J. Cheung, M. Madesh, 2018, American journal of physiology. Cell physiology.

Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy

S. Merali, Xueqian Zhang, J. Cheung, 2020, Cell Death & Disease.

An Integrated Framework for Genome Analysis Reveals Numerous Previously Unrecognizable Structural Variants in Leukemia Patients’ Samples

J. Broach, Feng Yue, A. Hastie, 2019, bioRxiv.

The Role of TRP Channels in Oxidative Stress-induced Cell Death

B. A. Miller, B. Miller, B. A. Miller, 2006, The Journal of Membrane Biology.

Role of TRPM2 in cell proliferation and susceptibility to oxidative stress.

J. Cheung, Jason K. Kim, Shu-Jen Chen, 2013, American journal of physiology. Cell physiology.

RNA dependent DNA synthesis in cell free preparations of human leukemia cells.

B. Miller, W. H. Murphy, W. Ackermann, 1971, Biochemical and biophysical research communications.

Burst-forming units-erythroid from erythropoietic protoporphyria patients fluoresce under 405 nm light.

M. Mathews-Roth, B. Miller, R. Wise, 1996, Blood.

Butryic acid analogues augment gamma globin gene expression in neonatal erythroid progenitors.

D. Faller, S. Perrine, B. Miller, 1987, Biochemical and biophysical research communications.

TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.

J. Cheung, L. Penn, D. Carey, 2006, American journal of physiology. Cell physiology.

Alcohol feeding impedes early atherosclerosis in low-density lipoprotein receptor knockout mice: factors in addition to high-density lipoprotein-apolipoprotein A1 are involved.

R. C. Lin, J. Dai, B. Miller, 1997, Alcoholism, clinical and experimental research.

The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1

J. Cheung, Hong-Gang Wang, George-Lucian Moldovan, 2022, Scientific Reports.

The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury.

Xueqian Zhang, J. Cheung, W. Koch, 2013, American journal of physiology. Heart and circulatory physiology.

TRPM2 Function and Potential as a Drug Target

B. Miller, 2012 .

TRP channels as mediators of oxidative stress.

B. Miller, Wenyi Zhang, 2011, Advances in experimental medicine and biology.

Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.

J. Cheung, B. Miller, Qin Tong, 2007, American journal of physiology. Cell physiology.

Inhibition of TRPM2 function by PARP inhibitors protects cells from oxidative stress‐induced death

B. Miller, 2004, British journal of pharmacology.

Activation of abundant precursors associated with the response of Mlsa H-2k spleens to Mlsc antigen.

L. Jenski, B. Miller, M. Belloni, 1987, Immunological investigations.

Concentrations of apolipoproten AI, AII, and E in plasma and lipoprotein fractions of alcoholic patients: Gender differences in the effects of alcohol

R. C. Lin, T. J. Kelly, B. Miller, 1995, Hepatology.

Francisella tularensis Catalase Restricts Immune Function by Impairing TRPM2 Channel Activity*

J. Melendez, A. Chandrasekaran, M. Trebak, 2015, The Journal of Biological Chemistry.

The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression

J. Cheung, Hong-Gang Wang, I. Hirschler-Laszkiewicz, 2022, Scientific Reports.

A deletion/insertion polymorphism in the human BCR gene on chromosome 22.

C. Westbrook, B. Blazar, C. Rubin, 1988, Nucleic acids research.

Erythropoietin stimulates a rise in intracellular-free calcium concentration in single BFU-E derived erythroblasts at specific stages of differentiation.

D. Tillotson, B. Miller, R. Scaduto, 1989, Blood.

and PARP cleavage caspases hematopoietic cell death through activation of TRPM2 is an ion channel that modulates

T. Gudermann, J. Cheung, L. Penn, 2010 .

Analysis of high fetal hemoglobin production in sickle cell anemia patients from the Eastern Province of Saudi Arabia.

S. Orkin, N. Olivieri, D. Nathan, 1987, Progress in clinical and biological research.

Anemia But Other bHLH Proteins Are Deficient Expression of SCL Is Normal in Transfusion-Dependent Diamond-Blackfan

C. Begley, N. Olivieri, G. Clawson, 1997 .

Conditions for an in vitro culture of murine mixed hematopoietic colonies and their putative cellular origin

A. Huang, B. Miller, C. Dunn, 1982 .

Role of TRPM2 in cell proliferation and susceptibility to oxidative stress.

J. Cheung, Jason K. Kim, Shu-Jen Chen, 2013, American journal of physiology. Cell physiology.

The Nuclear Migration Gene Nudc and Human Hematopoiesis

G. Reaman, S. Osmani, C. Gocke, 2000, Leukemia and Lymphoma.

Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance.

Xueqian Zhang, J. Cheung, W. Koch, 2015, American journal of physiology. Heart and circulatory physiology.

Thy-1 antigen in murine hematopoietic progenitor differentiation.

J. Lipton, B. Miller, 1983, Progress in clinical and biological research.