R. Dirven

发表

Mutation in blood coagulation factor V associated with resistance to activated protein C

Pieter H. Reitsma, Bobby P. C. Koeleman, P. Reitsma, 1994, Nature.

No evidence for a direct effect of von Willebrand factor's ABH blood group antigens on von Willebrand factor clearance

P. Reitsma, J. Eikenboom, G. Castaman, 2015, Journal of thrombosis and haemostasis : JTH.

P. Reitsma, G. Castaman, R. Dirven, 2015 .

VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease.

J. Goudemand, J. Eikenboom, J. Batlle, 2013, Blood.

THROMBOSIS AND HEMOSTASIS VWF propeptide and ratios between VWF , VWF propeptide , and FVIII in the characterization of type 1 von Willebrand disease

J. Goudemand, J. Eikenboom, J. Batlle, 2013 .

Severity of bleeding tendency in von Willebrand disease is associated with von Willebrand factor string formation

Voorberg, Jan, R. Dirven, 2012 .

Biogenesis and exocytosis of Weibel-Palade bodies is affected by naturally occurring variants within the von Willebrand factor A1-A3 domains

P. Reitsma, J. Voorberg, K. Valentijn, 2012 .

Biogenesis of Weibel-Palade bodies in von Willebrand’s disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation

P. Reitsma, J. Voorberg, K. Valentijn, 2012, Haematologica.

Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease*

P. Reitsma, A. Koster, J. Voorberg, 2011, The Journal of Biological Chemistry.

Variability of von Willebrand factor‐related parameters in endothelial colony forming cells

E. Weijers, J. Eikenboom, R. Dirven, 2019, Journal of thrombosis and haemostasis : JTH.

Factor Va Is Inactivated by Activated Protein C in the Absence of Cleavage Sites at Arg-306, Arg-506, and Arg-679*

R. Bertina, J. Rosing, H. L. Vos, 2004, Journal of Biological Chemistry.

Endothelial characteristics in healthy endothelial colony forming cells; generating a robust and valid ex vivo model for vascular disease

E. Weijers, J. Eikenboom, P. James, 2020, Journal of thrombosis and haemostasis : JTH.

The activated protein C (APC)-resistant phenotype of APC cleavage site mutants of recombinant factor V in a reconstituted plasma model

R. Bertina, J. Rosing, H. L. Vos, 2002, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The Prothrombin 20210 A Allele Is Frequently Coinherited in Young Carriers of the Factor V Arg 506 to Gln Mutation With Venous Thrombophilia

J. Jansen, B. Koeleman, B. A. Reijden, 2017 .

The R306G and R506Q mutations in coagulation Factor V reveals additional cleavage sites for Activated Protein C in the R313-R321 region and at R505.

R. Bertina, H. L. Vos, R. Dirven, 2010, Thrombosis research.

Expression of tissue factor and tissue factor pathway inhibitor in monocytes in response to bacterial lipopolysaccharide and phorbolester

P. Reitsma, R. Bertina, R. Dirven, 1994, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Tissue Factor-Induced Coagulation Can Be Inhibited by Aprotinin (Trasylol)

R. Bertina, R. Dirven, A. Van den Besselaar, 1993, Thrombosis and Haemostasis.

Characterization of an immunologic polymorphism (D79H) in the heavy chain of factor V

F. Rosendaal, R. Bertina, H. Vos, 2004, Journal of thrombosis and haemostasis : JTH.

Storage and secretion of naturally occurring von Willebrand factor A domain variants

P. Reitsma, J. Voorberg, K. Valentijn, 2014, British journal of haematology.

Characterization of large in-frame von Willebrand factor deletions highlights differing pathogenic mechanisms.

D. Hampshire, J. Goudemand, C. Halldén, 2020, Blood advances.

The R2-haplotype associated Asp2194Gly mutation in the light chain of human factor V results in lower expression levels of FV, but has no influence on the glycosylation of Asn2181

R. Bertina, R. Dirven, M. Kolfschoten, 2003, Thrombosis and Haemostasis.

Ex vivo Improvement of a von Willebrand Disease Type 2A Phenotype Using an Allele-Specific Small-Interfering RNA

S. Anvar, J. Eikenboom, F. Leebeek, 2020, Thrombosis and Haemostasis.

Correction of a dominant‐negative von Willebrand factor multimerization defect by small interfering RNA‐mediated allele‐specific inhibition of mutant von Willebrand factor

J. Eikenboom, B. V. van Vlijmen, R. Dirven, 2018, Journal of thrombosis and haemostasis : JTH.

Ex vivo Improvementof a vonWillebrandDisease Type2A Phenotype Using an Allele-Specific Small-Interfering RNA

S. Anvar, J. Eikenboom, F. Leebeek, 2020 .

Factor Va is inactivated by APC in the absence of cleavage sites at Arg 306 , Arg 506 and Arg 679

R. Bertina, J. Rosing, R. Dirven, 2003 .

Angiogenic characteristics of blood outgrowth endothelial cells from patients with von Willebrand disease

P. Reitsma, J. Voorberg, J. Eikenboom, 2015, Journal of thrombosis and haemostasis : JTH.

Unraveling von Willebrand factor extracellular traps

P. Reitsma, J. Voorberg, K. Valentijn, 2013 .

Biogenesis of Weibel-Palade bodies in von Willebrand’s disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation

P. Reitsma, J. Voorberg, K. Valentijn, 2012, Haematologica.

Small interfering RNA–mediated allele-selective silencing of von Willebrand factor in vitro and in vivo

J. Eikenboom, B. V. van Vlijmen, R. Dirven, 2023, Blood advances.

Approaches to induce the maturation process of human induced pluripotent stem cell derived-endothelial cells to generate a robust model

R. Dirven, Jeroen Eikenboom, Suzan de Boer, 2024, PloS one.