Huilin Zhao

发表

Functional Insights of MraZ on the Pathogenicity of Staphylococcus aureus

Bingjie Wang, Jingjing Duan, Ye Jin, 2021, Infection and drug resistance.

Design, synthesis, and evaluation of orally active benzimidazoles and benzoxazoles as vascular endothelial growth factor-2 receptor tyrosine kinase inhibitors.

Daniel Elbaum, P. Gallant, A. Coxon, 2007, Journal of medicinal chemistry.

Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.

David P. Carney, P. Gallant, M. Morrison, 2011, Bioorganic & medicinal chemistry letters.

Structure-Based Design of Potent and Selective CK1γ Inhibitors.

H. Bregman, J. Newcomb, Xin Huang, 2012, ACS medicinal chemistry letters.

Methicillin-resistant Staphylococcus aureus in China: a multicentre longitudinal study and whole-genome sequencing

Liang Chen, Yanlei Xu, Huilin Zhao, 2022, Emerging microbes & infections.

The Co-occurrence of NDM-5, MCR-1, and FosA3-Encoding Plasmids Contributed to the Generation of Extensively Drug-Resistant Klebsiella pneumoniae

Bingjie Wang, Yanlei Xu, Huilin Zhao, 2022, Frontiers in Microbiology.

The Prevalence and Determinants of Fusidic Acid Resistance Among Methicillin-Resistant Staphylococcus aureus Clinical Isolates in China

Liang Chen, Baoshan Wan, Yanlei Xu, 2021, Frontiers in Medicine.

Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.

P. Gallant, T. Bush, M. Morrison, 2010, Journal of medicinal chemistry.

Molecular Characteristics of Rifampin-Sensitive and -Resistant Isolates and Characteristics of rpoB Gene Mutations in Methicillin-Resistant Staphylococcus aureus

Bingjie Wang, Huilin Zhao, Xinyi Wang, 2021, Infection and drug resistance.

Molecular characteristic of rifampin-sensitive and resistant isolates and characteristics of rpoB gene mutations in MRSA

Huilin Zhao, Xinyi Wang, L. Rao, 2021 .

Virtual screening and molecular dynamics simulation for identification of natural antiviral agents targeting SARS-CoV-2 NSP10

Lei He, Huilin Zhao, Ri-lei Yu, 2022, Biochemical and Biophysical Research Communications.

Small-molecule compound SYG-180-2-2 attenuates Staphylococcus aureus virulence by inhibiting hemolysin and staphyloxanthin production

Yanghua Xiao, Bingjie Wang, Yanlei Xu, 2022, Frontiers in Cellular and Infection Microbiology.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

In Vitro Activity of Vancomycin, Teicoplanin, Linezolid and Daptomycin Against Methicillin-Resistant Staphylococcus aureus Isolates Collected from Chinese Hospitals in 2018–2020

Bingjie Wang, Yanlei Xu, Huilin Zhao, 2021, Infection and drug resistance.

Identification of small molecule inhibitors of proline-rich tyrosine kinase 2 (Pyk2) with osteogenic activity in osteoblast cells.

W. Richards, Matthew R. Lee, D. Bauer, 2009, Bioorganic & medicinal chemistry letters.

Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

Xin Huang, David Powers, Daniela Metz, 2006, Journal of medicinal chemistry.

Phylogenetic analysis and virulence characteristics of methicillin-resistant Staphylococcus aureus ST764-SCCmec II: an emerging hypervirulent clone ST764-t1084 in China

Yanghua Xiao, Bingjie Wang, Yanlei Xu, 2023, Emerging microbes & infections.

Dissemination of Methicillin-Resistant Staphylococcus aureus Sequence Type 764 Isolates with Mupirocin Resistance in China

Bingjie Wang, Yanlei Xu, Huilin Zhao, 2023, Microbiology spectrum.

Small-Molecule Compound SYG-180-2-2 to Effectively Prevent the Biofilm Formation of Methicillin-Resistant Staphylococcus aureus

L. Zhan, Bingjie Wang, Yanlei Xu, 2022, Frontiers in Microbiology.

Identification of methicillin-resistant Staphylococcus aureus ST8 isolates in China with potential high virulence

Liang Chen, Yanlei Xu, Huilin Zhao, 2022, Emerging microbes & infections.

Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors.

P. Gallant, M. Morrison, P. Rose, 2007, Bioorganic & medicinal chemistry letters.

Structural basis for the interaction between casein kinase 1 delta and a potent and selective inhibitor.

Xin Huang, A. Long, Huilin Zhao, 2012, Journal of medicinal chemistry.

Crystal structure of an inactive Akt2 kinase domain.

Xin Huang, P. Rose, Yan Gu, 2003, Structure.

Phylogenetic Analysis and Virulence Characteristics of Methicillin-Resistant Staphylococcus aureus ST45 in China: a Hyper-Virulent Clone Associated with Bloodstream Infections

Yanghua Xiao, Liang Chen, Bingjie Wang, 2023, mSystems.

Co-occurrence of OXA-232, RmtF-encoding plasmids, and pLVPK-like virulence plasmid contributed to the generation of ST15-KL112 hypervirulent multidrug-resistant Klebsiella pneumoniae

Liangxing Wang, Bingjie Wang, Huilin Zhao, 2023, Frontiers in Microbiology.

Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.

Richard Kendall, P. Gallant, M. Morrison, 2007, Journal of medicinal chemistry.

Structural basis for the potent and selective inhibition of casein kinase 1 epsilon.

Xin Huang, A. Long, Huilin Zhao, 2012, Journal of medicinal chemistry.

The small molecule ZY-214-4 may reduce the virulence of Staphylococcus aureus by inhibiting pigment production

L. Zhan, Qing Zhan, Yanlei Xu, 2021, BMC microbiology.

Co-Occurrence of Rare ArmA-, RmtB-, and KPC-2–Encoding Multidrug-Resistant Plasmids and Hypervirulence iuc Operon in ST11-KL47 Klebsiella pneumoniae

Bingjie Wang, Yanlei Xu, Huilin Zhao, 2022, Microbiology spectrum.

Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.

P. Gallant, M. Morrison, D. Elbaum, 2006, Journal of medicinal chemistry.

Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase.

David Powers, Paul Hughes, Richard Kendall, 2007, Journal of medicinal chemistry.

Phenotypic and genomic analysis of the hypervirulent ST22 methicillin-resistant Staphylococcus aureus in China

Yanghua Xiao, Liang Chen, Baoshan Wan, 2023, mSystems.

Small-Molecule Compound CY-158-11 Inhibits Staphylococcus aureus Biofilm Formation

Yanghua Xiao, Bingjie Wang, Yanlei Xu, 2023, Microbiology spectrum.

Characterization difference of typical KL1, KL2 and ST11-KL64 hypervirulent and carbapenem-resistant Klebsiella pneumoniae.

Bingjie Wang, Yanlei Xu, Huilin Zhao, 2023, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.