Saqib Kidwai

发表

System-Wide Analysis Unravels the Differential Regulation and In Vivo Essentiality of Virulence-Associated Proteins B and C Toxin-Antitoxin Systems of Mycobacterium tuberculosis

P. Tiwari, Ramandeep Singh, A. Deep, 2018, The Journal of infectious diseases.

Corrigendum: MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs.

P. Tiwari, Ramandeep Singh, O. Narayan, 2015, Nature communications.

NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G

D. Saini, N. Srinivasan, M. Essafi, 2019, Antimicrobial Agents and Chemotherapy.

Dual Mechanism of Action of 5-Nitro-1,10-Phenanthroline against Mycobacterium tuberculosis

D. Alland, P. Tiwari, Pradeep Kumar, 2017, Antimicrobial Agents and Chemotherapy.

Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner.

Abhirup Ghosh, S. Saha, Ramandeep Singh, 2017, Biochimica et biophysica acta. General subjects.

NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy

Gagandeep, Ramandeep Singh, R. Shaliwal, 2020, Frontiers in Microbiology.

VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response

K. Datta, H. Gowda, Arun Sharma, 2020, Science Advances.

MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs

P. Tiwari, Ramandeep Singh, O. Narayan, 2015, Nature Communications.

Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

S. Saha, Ramandeep Singh, D. Chaudhary, 2022, Scientific Reports.

Synthesis and Antitubercular Activity Evaluation of Novel Unsymmetrical Cyclohexane‐1,2‐diamine Derivatives

Beena, Ramandeep Singh, S. Joshi, 2012, Archiv der Pharmazie.

Bile acid amphiphiles with tunable head groups as highly selective antitubercular agents

A. Singh, Ramandeep Singh, Vedagopuram Sreekanth, 2014 .

Novel isoniazid–amidoether derivatives: synthesis, characterization and antimycobacterial activity evaluation

Beena, A. Tyagi, Ramandeep Singh, 2015 .

Synthesis of novel 1,2,3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation.

Beena, A. Tyagi, Ramandeep Singh, 2014, European journal of medicinal chemistry.

CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs

Ramandeep Singh, D. Chaudhary, Saqib Kidwai, 2018, Front. Cell. Infect. Microbiol..

Polyphosphate Deficiency in Mycobacterium tuberculosis Is Associated with Enhanced Drug Susceptibility and Impaired Growth in Guinea Pigs

P. Tiwari, Ramandeep Singh, Saqib Kidwai, 2013, Journal of bacteriology.

Exopolyphosphatases PPX1 and PPX2 from Mycobacterium tuberculosis regulate dormancy response and pathogenesis.

D. Saini, P. Tiwari, Ramandeep Singh, 2022, Microbial pathogenesis.

3D QSAR-based design and liquid phase combinatorial synthesis of 1,2-disubstituted benzimidazole-5-carboxylic acid and 3-substituted-5H-benzimidazo[1,2-d][1,4]benzodiazepin-6(7H)-one derivatives as anti-mycobacterial agents.

V. Vyas, M. Ghate, Ramandeep Singh, 2019, MedChemComm.

Design, Synthesis, Characterization, and Anti-tubercular activity of Novel Ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate Analogues: Molecular Target Identification and Molecular Docking Studies

Ramandeep Singh, Saqib Kidwai, Sandeep Chandrashekharappa, 2023, Journal of Molecular Structure.

Synthesis of 1,3,4-oxadiazole and imidazo[1,2-a]pyridine based molecular hybrids and their in vitro antituberculosis and cytotoxicity studies

Ramandeep Singh, D. Rawat, Saqib Kidwai, 2019 .

Design and synthesis of benzimidazole derivatives as antimycobacterial agents

Ramandeep Singh, D. Rawat, Padam Singh, 2022, Journal of biochemical and molecular toxicology.

Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin–antitoxin system: targeting a tRNase to tackle mycobacterial adaptation

Prabhakar Tiwari, Ramandeep Singh, Sakshi Agarwal, 2018, Nucleic acids research.

Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis

D. Saini, P. Tiwari, Ramandeep Singh, 2019, The Journal of Biological Chemistry.

Novel fluorophenyl tethered thiazole and chalcone analogues as potential anti-tubercular agents: Design, synthesis, biological and in silico evaluations

R. Chauhan, Ramandeep Singh, Saqib Kidwai, 2022, Journal of Molecular Structure.

Disulfiram inhibits M. tuberculosis growth by altering methionine pool, redox status and host-immune response

Bernett Lee, Pradeep Kumar, Ramandeep Singh, 2020, bioRxiv.

A natural product inspired hybrid approach towards the synthesis of novel pentamidine based scaffolds as potential anti-parasitic agents.

K. Srivastava, S. Puri, Suman Gupta, 2013, Bioorganic & Medicinal Chemistry Letters.

Synthesis and evaluation of antimycobacterial activity of riboflavin derivatives.

Ramandeep Singh, Manisha Singh, V. Khedkar, 2021, Bioorganic & medicinal chemistry letters.

Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis

P. Tiwari, Ramandeep Singh, S. Agarwal, 2016, Scientific Reports.

Discovery of small molecule inhibitors of Mycobacterium tuberculosis ClpC1: SAR studies and antimycobacterial evaluation

Ramandeep Singh, Saqib Kidwai, S. Sundriyal, 2023, Results in Chemistry.

Design, Synthesis and In-vitro Antitubercular Evaluation of Novel 7-methoxy Pyrrolo[1,2-a]quinoline Analogues as CYP 121 Inhibitors

Ramandeep Singh, Saqib Kidwai, Sandeep Chandrashekharappa, 2023, Journal of Molecular Structure.

Novel 4,5-dibromo-N-phenyl-1H-pyrrole-2-carboxamide Hybrids as Promising DNA Gyrase Inhibitors: Design, Synthesis and Antimicrobial Evaluation

A. Kajee, Saqib Kidwai, M. Palkar, 2023, Journal of Molecular Structure.

Identification and optimization of pyridine carboxamide-based scaffold as a drug lead for Mycobacterium tuberculosis

Saqib Kidwai, R. Dhiman, Saurabh Chugh, 2024, Antimicrobial agents and chemotherapy.

Polyphosphate kinase-1 regulates bacterial and host metabolic pathways involved in pathogenesis of Mycobacterium tuberculosis

Ramandeep Singh, Mitul Srivastava, Shailendra Asthana, 2024, Proceedings of the National Academy of Sciences of the United States of America.