A. Rodríguez-García

发表

Target genes of the Streptomyces tsukubaensis FkbN regulator include most of the tacrolimus biosynthesis genes, a phosphopantetheinyl transferase and other PKS genes

J. Martín, María Ordóñez-Robles, A. Rodríguez-García, 2016, Applied Microbiology and Biotechnology.

Transcriptomic Analysis of Streptomyces coelicolor Differentiation in Solid Sporulating Cultures: First Compartmentalized and Second Multinucleated Mycelia Have Different and Distinctive Transcriptomes

J. Martín, Á. Manteca, P. Yagüe, 2013, PloS one.

A regulatory gene (ccaR) required for cephamycin and clavulanic acid production in Streptomyces clavuligerus: amplification results in overproduction of both beta-lactam compounds

J. Martín, J. Martín, P. Liras, 1997, Journal of bacteriology.

CcaR Is an Autoregulatory Protein That Binds to the ccaR and cefD-cmcI Promoters of the Cephamycin C-Clavulanic Acid Cluster in Streptomyces clavuligerus

J. Martín, P. Liras, I. Santamarta, 2002, Journal of bacteriology.

ArgR of Streptomyces coelicolor Is a Versatile Regulator

J. Martín, P. Liras, I. Santamarta, 2012, PloS one.

The dynamic architecture of the metabolic switch in Streptomyces coelicolor

Kay Nieselt, Rainer Breitling, Eriko Takano, 2010, BMC Genomics.

Genome‐wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a ΔphoP mutant

C. Barreiro, J. Martín, Fernando Santos-Beneit, 2007, Proteomics.

Cross‐talk between two global regulators in Streptomyces: PhoP and AfsR interact in the control of afsS, pstS and phoRP transcription

J. Martín, Fernando Santos-Beneit, Antonio Rodríguez-García, 2009, Molecular microbiology.

Novel Two-Component Systems Implied in Antibiotic Production in Streptomyces coelicolor

M. Díaz, R. Santamaría, A. Rodríguez-García, 2011, PloS one.

Two Proteins with Ornithine Acetyltransferase Activity Show Different Functions in Streptomyces clavuligerus: Oat2 Modulates Clavulanic Acid Biosynthesis in Response to Arginine

J. Martín, P. Liras, A. Rodríguez-García, 2004, Journal of bacteriology.

ArgR of Streptomyces coelicolor Is a Pleiotropic Transcriptional Regulator: Effect on the Transcriptome, Antibiotic Production, and Differentiation in Liquid Cultures

Á. Manteca, P. Yagüe, P. Liras, 2018, Front. Microbiol..

Discovering the potential of S. clavuligerus for bioactive compound production: cross-talk between the chromosome and the pSCL4 megaplasmid

Y. Martínez-Burgo, P. Liras, A. Rodríguez-García, 2017, BMC Genomics.

Transcriptomic studies of phosphate control of primary and secondary metabolism in Streptomyces coelicolor

Kay Nieselt, Nigel J. Burroughs, Trond E. Ellingsen, 2012, Applied Microbiology and Biotechnology.

Self-control of the PHO regulon: the PhoP-dependent protein PhoU controls negatively expression of genes of PHO regulon in Streptomyces coelicolor

J. Martín, A. Rodríguez-García, A. Sola-Landa, 2017, The Journal of Antibiotics.

Analysis of the Pho regulon in Streptomyces tsukubaensis.

J. Martín, María Ordóñez-Robles, A. Rodríguez-García, 2017, Microbiological research.

The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: comparison in Streptomyces coelicolor and Streptomyces avermitilis

J. Martín, P. Liras, A. Rodríguez-García, 2017, The Journal of Antibiotics.

Transcriptional response to vancomycin in a highly vancomycin-resistant Streptomyces coelicolor mutant.

J. Martín, Á. Manteca, P. Yagüe, 2014, Future microbiology.

Genome-wide analysis of the regulation of pimaricin production in Streptomyces natalensis by reactive oxygen species

P. Moradas-Ferreira, A. Rodríguez-García, M. V. Mendes, 2014, Applied Microbiology and Biotechnology.

Complex Transcriptional Control of the Antibiotic Regulator afsS in Streptomyces: PhoP and AfsR Are Overlapping, Competitive Activators

J. Martín, A. Rodríguez-García, F. Santos-Beneit, 2011, Journal of bacteriology.

The RNA Polymerase Omega Factor RpoZ Is Regulated by PhoP and Has an Important Role in Antibiotic Biosynthesis and Morphological Differentiation in Streptomyces coelicolor

Mónica Barriuso-Iglesias, J. Martín, Miriam Martínez-Castro, 2011, Applied and Environmental Microbiology.

Transcriptomic Analysis of Liquid Non-Sporulating Streptomyces coelicolor Cultures Demonstrates the Existence of a Complex Differentiation Comparable to That Occurring in Solid Sporulating Cultures

J. Martín, Á. Manteca, P. Yagüe, 2014, PloS one.

Cross‐talk of global nutritional regulators in the control of primary and secondary metabolism in Streptomyces

C. Prieto, J. Martín, A. Rodríguez-García, 2011, Microbial biotechnology.

Modulation of multiple gene clusters expression by a single PAS-LuxR transcriptional regulator

A. Rodríguez-García, F. Santos-Beneit, Tamara D. Payero, 2022, bioRxiv.

Complete genome sequence of 'Mycobacterium neoaurum' NRRL B-3805, an androstenedione (AD) producer for industrial biotransformation of sterols.

C. Barreiro, S. Macdonald, Margaret C. M. Smith, 2016, Journal of biotechnology.

The pcd Gene Encoding Piperideine-6-Carboxylate Dehydrogenase Involved in Biosynthesis of α-Aminoadipic Acid Is Located in the Cephamycin Cluster ofStreptomyces clavuligerus

J. Martín, F. Enguita, P. Liras, 1998, Journal of bacteriology.

Complex transcriptional control of the antibiotic regulator

J. Martín, A. Rodríguez-García, F. Santos-Beneit, 2011 .

Characterization and expression of the arginine biosynthesis gene cluster of Streptomyces clavuligerus.

J. Martín, P. Liras, R. Pérez-Redondo, 2000, Journal of molecular microbiology and biotechnology.

Genome Sequencing of Steroid Producing Bacteria Using Ion Torrent Technology and a Reference Genome.

C. Barreiro, R. Pérez-Redondo, A. Rodríguez-García, 2017, Methods in molecular biology.

The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene.

J. Martín, P. Liras, R. Pérez-Redondo, 1998, Gene.

Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF

A. Rodríguez-García, J. F. Aparicio, F. Santos-Beneit, 2022, Antibiotics.

Transcriptional Studies on a Streptomyces clavuligerus oppA2 Deletion Mutant: N-Acetylglycyl-Clavaminic Acid Is an Intermediate of Clavulanic Acid Biosynthesis

J. Martín, Y. Martínez-Burgo, P. Liras, 2018, Applied and Environmental Microbiology.

Deletion of the pyc Gene Blocks Clavulanic Acid Biosynthesis Except in Glycerol-Containing Medium: Evidence for Two Different Genes in Formation of the C3 Unit

J. Martín, P. Liras, R. Pérez-Redondo, 1999, Journal of bacteriology.

Multi-omics Study of Planobispora rosea, Producer of the Thiopeptide Antibiotic GE2270A

R. Breitling, G. Thomas, E. Takano, 2021, mSystems.

Evolution of the clusters of genes for β-lactam antibiotics: a model for evolutive combinatorial assembly of new β-lactams

J. Martín, P. Liras, A. Rodríguez-García, 1998 .

Phosphate-dependent regulation of the low- and high-affinity transport systems in the model actinomycete Streptomyces coelicolor.

J. Martín, J. Martín, A. Rodríguez-García, 2008, Microbiology.

Genome-wide analysis of the regulation of pimaricin production in Streptomyces natalensis by reactive oxygen species

A. Rodríguez-García, M. V. Mendes, J. F. Aparicio, 2014, Applied Microbiology and Biotechnology.

The gamma-butyrolactone receptors BulR1 and BulR2 of Streptomyces tsukubaensis: tacrolimus (FK506) and butyrolactone synthetases production control

C. Barreiro, J. Martín, G. López, 2014, Applied Microbiology and Biotechnology.

LAL Regulators SCO0877 and SCO7173 as Pleiotropic Modulators of Phosphate Starvation Response and Actinorhodin Biosynthesis in Streptomyces coelicolor

J. Martín, A. Rodríguez-García, Susana M. Guerra, 2012, PloS one.

Natural and synthetic tetracycline-inducible promoters for use in the antibiotic-producing bacteria Streptomyces

R. Pérez-Redondo, A. Rodríguez-García, Margaret C. M. Smith, 2005, Nucleic acids research.

RNA-Seq-Based Comparative Transcriptomics: RNA Preparation and Bioinformatics.

C. Barreiro, A. Rodríguez-García, A. Sola-Landa, 2017, Methods in molecular biology.

Streptomyces tsukubaensis as a new model for carbon repression: transcriptomic response to tacrolimus repressing carbon sources

J. Martín, P. Liras, María Ordóñez-Robles, 2017, Applied Microbiology and Biotechnology.

Genome-wide transcriptome response of Streptomyces tsukubaensis to N-acetylglucosamine: effect on tacrolimus biosynthesis.

J. Martín, María Ordóñez-Robles, A. Rodríguez-García, 2018, Microbiological research.

A 1.8-Mb-reduced Streptomyces clavuligerus genome: relevance for secondary metabolism and differentiation

J. Martín, Y. Martínez-Burgo, P. Liras, 2014, Applied Microbiology and Biotechnology.

Evolution of the clusters of genes for beta-lactam antibiotics: a model for evolutive combinatorial assembly of new beta-lactams.

J. Martín, P. Liras, A. Rodríguez-García, 1998, International microbiology : the official journal of the Spanish Society for Microbiology.

Draft Genome of Streptomyces tsukubaensis NRRL 18488, the Producer of the Clinically Important Immunosuppressant Tacrolimus (FK506)

C. Prieto, C. García-Estrada, A. Tauch, 2012, Journal of bacteriology.

Arginine boxes and the argR gene in Streptomyces clavuligerus: evidence for a clear regulation of the arginine pathway

J. Martín, P. Liras, A. Rodríguez-García, 1997, Molecular microbiology.

Metabolic Switches and Adaptations Deduced from the Proteomes of Streptomyces coelicolor Wild Type and phoP Mutant Grown in Batch Culture*

Kay Nieselt, David A. Hodgson, Nigel J. Burroughs, 2011, Molecular & Cellular Proteomics.

Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor

J. Martín, W. Wohlleben, A. Rodríguez-García, 2012, Nucleic acids research.

Identification of different promoters in the absA1–absA2 two-component system, a negative regulator of antibiotic production in Streptomyces coelicolor

J. Martín, A. Rodríguez-García, Fernando Santos-Beneit, 2013, Molecular Genetics and Genomics.

Phosphate control over nitrogen metabolism in Streptomyces coelicolor: direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP

J. Martín, Juan F. Martín, Fernando Santos-Beneit, 2009, Nucleic acids research.

Target genes and structure of the direct repeats in the DNA-binding sequences of the response regulator PhoP in Streptomyces coelicolor

J. Martín, A. Apel, A. Rodríguez-García, 2008, Nucleic acids research.

Binding of PhoP to promoters of phosphate‐regulated genes in Streptomyces coelicolor: identification of PHO boxes

J. Martín, A. Rodríguez-García, A. Sola-Landa, 2005, Molecular microbiology.

Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis

A. Truman, Y. Martínez-Burgo, P. Liras, 2019, Front. Microbiol..

Phosphate control of phoA, phoC and phoD gene expression in Streptomyces coelicolor reveals significant differences in binding of PhoP to their promoter regions.

J. Martín, A. Apel, A. Rodríguez-García, 2007, Microbiology.

Phosphate and carbon source regulation of two PhoP-dependent glycerophosphodiester phosphodiesterase genes of Streptomyces coelicolor.

J. Martín, A. Apel, A. Rodríguez-García, 2009, Microbiology.

Reference-Grade Genome and Large Linear Plasmid of Streptomyces rimosus: Pushing the Limits of Nanopore Sequencing

H. Petković, J. Zucko, G. Thomas, 2022, Microbiology spectrum.

Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus.

J. Martín, P. Liras, I. Santamarta, 2006, Research in microbiology.