A. Khoshnan

发表

Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.

P. Patterson, P. Reinhart, A. Khoshnan, 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Elevated IKKα Accelerates the Differentiation of Human Neuronal Progenitor Cells and Induces MeCP2-Dependent BDNF Expression

P. Patterson, A. Khoshnan, 2012, PloS one.

Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cell-based therapies and studies related to the expansion of double-positive T-cells during aging.

A. Nel, R. Effros, C. June, 2000, Clinical Immunology.

DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease.

F. Giorgini, E. W. Green, L. Miller-Fleming, 2014, Human molecular genetics.

Antibodies and intrabodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms.

P. Patterson, S. Ou, A. Khoshnan, 2013, Methods in molecular biology.

Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms.

P. Patterson, S. Ou, A. Khoshnan, 2004, Methods in molecular biology.

Primary human CD4+ T cells contain heterogeneous I kappa B kinase complexes: role in activation of the IL-2 promoter.

A. Nel, A. Manning, C. June, 1999, Journal of immunology.

The Physical Association of Protein Kinase Cθ with a Lipid Raft-Associated Inhibitor of κB Factor Kinase (IKK) Complex Plays a Role in the Activation of the NF-κB Cascade by TCR and CD281

A. Nel, C. Tindell, A. Khoshnan, 2000, The Journal of Immunology.

Gut Bacteria Regulate the Pathogenesis of Huntington’s Disease in Drosophila Model

Jung Hyun Yoo, J. Marsh, A. Huda, 2021, bioRxiv.

TCR and CD 28 B Cascade by κ in the Activation of the NFB Factor Kinase ( IKK ) Complex Plays a Role κ with a Lipid Raft-Associated Inhibitor of θ The Physical Association of Protein Kinase C

A. Nel, C. Tindell, A. Khoshnan, 2000 .

The NF-κB Cascade Is Important in Bcl-xL Expression and for the Anti-Apoptotic Effects of the CD28 Receptor in Primary Human CD4+ Lymphocytes1

A. Nel, B. Bennett, C. Tindell, 2000, The Journal of Immunology.

The NF-kB Cascade Is Important in Bcl-xL Expression and for the Anti-Apoptotic Effects of the CD28 Receptor in Primary Human CD4 Lymphocytes

B. Bennett, A. Nel, C. Tindell, 2000 .

Trichomonas vaginalis with a double-stranded RNA virus has upregulated levels of phenotypically variable immunogen mRNA

J. Alderete, A. Khoshnan, 1994, Journal of virology.

Neurotoxicity of manganese oxide nanomaterials

P. Patterson, J. Hering, A. Khoshnan, 2009 .

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

S. Finkbeiner, M. Hayden, J. Marsh, 2009, The Journal of cell biology.

Activation of the IκB Kinase Complex and Nuclear Factor-κB Contributes to Mutant Huntingtin Neurotoxicity

P. Patterson, P. Reinhart, A. Khoshnan, 2004, The Journal of Neuroscience.

Characterization of double-stranded RNA satellites associated with the Trichomonas vaginalis virus

J. Alderete, A. Khoshnan, 1995, Journal of virology.

Hepatitis C Virus Core Protein Binds to the Cytoplasmic Domain of Tumor Necrosis Factor (TNF) Receptor 1 and Enhances TNF-Induced Apoptosis

M. Lai, C. Ware, A. Khoshnan, 1998, Journal of Virology.

IKK&bgr; and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD

Jung Hyun Yoo, Barbara Calamini, P. Patterson, 2017, Human molecular genetics.

Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin

Jung Hyun Yoo, P. Patterson, R. Langen, 2018, Human molecular genetics.

Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity

P. Patterson, A. Khoshnan, J. Ko, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Amplification of neurotoxic HTTex1 assemblies in human neurons

Jung Hyun Yoo, M. Kennedy, R. Langen, 2021, Neurobiology of Disease.

Sonicated fibrils of huntingtin exon-1 preferentially seed neurons and produce toxic assemblies

Jung Hyun Yoo, R. Langen, A. Khoshnan, 2021, bioRxiv.

IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model

A. Khoshnan, R. Soylu-Kucharz, Å. Petersén, 2022, iScience.

The role of IκB kinase complex in the neurobiology of Huntington's disease

P. Patterson, A. Khoshnan, 2011, Neurobiology of Disease.

IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington’s disease mouse model

Å. Petersén, A. Khoshnan, R. Soylu-Kucharz, 2021, bioRxiv.

IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin

P. Patterson, A. Khoshnan, J. Ko, 2009, PloS one.

Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

P. Patterson, D. Lo, A. Southwell, 2008, The Journal of Neuroscience.

Involvement of dsRNA virus in the protein compositionand growth kinetics of host Trichomonas vaginalis

D. Provenzano, J. Alderete, A. Khoshnan, 2014, Archives of Virology.

Multiple double-stranded RNA segments are associated with virus particles infecting Trichomonas vaginalis

J. Alderete, A. Khoshnan, 1993, Journal of virology.

Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice

E. Wanker, J. Grimm, G. Bates, 2021, Frontiers in Neuroscience.

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

L. Kaltenbach, S. Zeitlin, M. Arrasate, 2009 .

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

L. Kaltenbach, S. Zeitlin, M. Arrasate, 2009 .