C. Combs

发表

Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

A. Floden, Shanshan Li, C. Combs, 2005, The Journal of neuroscience : the official journal of the Society for Neuroscience.

A Pilot Study to Assess Effects of Long-Term Inhalation of Airborne Particulate Matter on Early Alzheimer-Like Changes in the Mouse Brain

Colin K. Combs, L. Wold, Dhaval P. Bhatt, 2015, PloS one.

Astrocytic biotransformation of trans-4-hydroxy-2-nonenal is dose-dependent.

A. Kubátová, M. Picklo, C. Combs, 2006, Chemical research in toxicology.

Amyloid Precursor Protein Mediates Proinflammatory Activation of Monocytic Lineage Cells*

C. Combs, C. Sondag, 2004, Journal of Biological Chemistry.

In utero exposure to fine particulate matter results in an altered neuroimmune phenotype 2 in adult mice 3 4

Wold, L. Wold, Joshua A. Kulas, 2018 .

Expression and function of APP and its metabolites outside the central nervous system

C. Combs, K. Puig, 2013, Experimental Gerontology.

Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain

M. Jensen, G. Combs, M. Sens, 2017, Scientific Reports.

Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer disease.

C. Combs, K. Puig, Lalida Rojanathammanee, 2013, The Journal of nutrition.

Amyloid Precursor Protein Mediates a Tyrosine Kinase-Dependent Activation Response in Endothelial Cells

M. Sens, C. Combs, S. Austin, 2009, The Journal of Neuroscience.

Pro-inflammatory responses in human monocytes are beta1-adrenergic receptor subtype dependent.

E. Sauter, Laurel A. Grisanti, J. Porter, 2010, Molecular immunology.

NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.

C. Norris, C. Combs, K. Puig, 2017, Journal of Alzheimer's disease : JAD.

Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity

M. Golovko, A. Floden, C. Combs, 2012, PloS one.

α1-Adrenergic Receptors Positively Regulate Toll-Like Receptor Cytokine Production from Human Monocytes and Macrophages

E. Sauter, Laurel A. Grisanti, J. Porter, 2011, Journal of Pharmacology and Experimental Therapeutics.

The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice

G. Taglialatela, Joshua A. Kulas, H. Brown-Borg, 2016, Neurobiology of Aging.

Nitrogen–Sulfur-Doped Graphene Quantum Dots with Metal Ion-Resistance for Bioimaging

Yingfen Wu, J. Zhao, Yuqian Xing, 2019, ACS Applied Nano Materials.

Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy

N. A. Smith, C. Combs, K. Nagamoto-Combs, 2019, Front. Cell. Neurosci..

Manipulating phagocyte activity in Alzheimer's disease.

C. Combs, 2010, Journal of Alzheimer's disease : JAD.

Amyloid precursor protein cross‐linking stimulates beta amyloid production and pro‐inflammatory cytokine release in monocytic lineage cells

C. Combs, C. Sondag, C. M. Sondag, 2006, Journal of neurochemistry.

Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Aβ1-40

C. Combs, C. Sondag, 2010, Journal of Neuroinflammation.

Alpha-synuclein expression modulates microglial activation phenotype.

A. Floden, C. Combs, E. Murphy, 2006, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Sex-Dependent Effects of Intestinal Microbiome Manipulation in a Mouse Model of Alzheimer’s Disease

Surjeet Singh, C. Combs, Harpreet Kaur, 2021, Cells.

Sex Steroids Effects on Asthma: A Network Perspective of Immune and Airway Cells

C. Combs, V. Sathish, N. Borkar, 2022, Cells.

Synthesis of Highly Near-Infrared Fluorescent Graphene Quantum Dots Using Biomass-Derived Materials for In Vitro Cell Imaging and Metal Ion Detection.

Yingfen Wu, J. Zhao, C. Combs, 2021, ACS applied materials & interfaces.

Are GLP‐1 receptor agonists useful against traumatic brain injury?

C. Combs, 2015, Journal of neurochemistry.

Amyloid Precursor Protein Expression Modulates Intestine Immune Phenotype

M. Sens, X. Zhou, C. Combs, 2011, Journal of Neuroimmune Pharmacology.

Microglia demonstrate age-dependent interaction with amyloid-β fibrils.

A. Floden, C. Combs, 2011, Journal of Alzheimer's disease : JAD.

Microglial Phenotype Is Regulated by Activity of the Transcription Factor, NFAT (Nuclear Factor of Activated T Cells)

C. Combs, K. Nagamoto-Combs, 2010, The Journal of Neuroscience.

Amyloid Precursor Protein Mediated Changes in Intestinal Epithelial Phenotype In Vitro

C. Combs, K. Puig, Gunjan D Manocha, 2015, PloS one.

Microglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype

A. Floden, C. Combs, 2007, Journal of Neuroscience Methods.

Particulate matter exposure exacerbates A β plaque deposition and gliosis in APP/PS1 mice

L. Wold, A. Floden, C. Combs, 2021 .

Microglia Demonstrate Age-Dependent Interaction with Beta-amyloid Fibrils

A. Floden, C. Combs, 2012 .

HLA-II-Dependent Neuroimmune Changes in Group A Streptococcal Necrotizing Fasciitis

Ganesh Ambigapathy, C. Combs, Suba Nookala, 2022, bioRxiv.

Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells

N. A. Smith, C. Combs, K. Nagamoto-Combs, 2018, Journal of Neuroinflammation.

Iba1 immunoreactivity is enhanced following an antigen retrieval treatment with EDTA, pH 6.0

C. Combs, A. Ghatak, 2014, MethodsX.

A novel cell line from spontaneously immortalized murine microglia

Joshua A. Kulas, C. Combs, K. Nagamoto-Combs, 2014, Journal of Neuroscience Methods.

Regulation of beta-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor alpha.

G. Landreth, J. C. Karlo, C. Combs, 2001, Neurochemistry international.

Cellular and Molecular Mechanisms of Glial Scarring and Progressive Cavitation: In Vivo and In VitroAnalysis of Inflammation-Induced Secondary Injury after CNS Trauma

Colin K. Combs, Jerry Silver, J. Silver, 1999, The Journal of Neuroscience.

Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells

N. A. Smith, C. Combs, K. Nagamoto-Combs, 2018, Journal of Neuroinflammation.

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia

C. Combs, C. Sondag, Gunjan Dhawan, 2009, Journal of Neuroinflammation.

The role of α-synuclein in brain lipid metabolism: a downstream impact on brain inflammatory response

G. Barceló-Coblijn, M. Golovko, C. Combs, 2009, Molecular and Cellular Biochemistry.

Brain changes associated with thromboxane receptor antagonist SQ 29,548 treatment in a mouse model

M. Golovko, C. Combs, K. Puig, 2015, Journal of neuroscience research.

Identification of Microglial Signal Transduction Pathways Mediating a Neurotoxic Response to Amyloidogenic Fragments of β-Amyloid and Prion Proteins

G. Landreth, S. Cannady, C. Combs, 1999, The Journal of Neuroscience.

Effects of Probiotic Supplementation on Short Chain Fatty Acids in the AppNL-G-F Mouse Model of Alzheimer's Disease.

H. Kaur, Surjeet Singh, D. Darland, 2020, Journal of Alzheimer's disease : JAD.

Salivary Aβ Secretion and Altered Oral Microbiome in Mouse Models of AD.

A. Floden, C. Combs, Suba Nookala, 2021, Current Alzheimer research.

Temporal progression of Alzheimer's disease in brains and intestines of transgenic mice

Abbie J. Smith, T. Saido, Takashi Saito, 2019, Neurobiology of Aging.

Overexpression of mutant amyloid-β protein precursor and presenilin 1 modulates enteric nervous system.

N. Foster, M. Sens, X. Zhou, 2015, Journal of Alzheimer's disease : JAD.

Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE−/− mice

C. Combs, S. Austin, 2010, Neurobiology of Aging.

Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer’s disease

M. Klug, H. Kaur, M. Golovko, 2020, Neurobiology of Aging.

Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis

K. Seyb, M. Glicksman, C. Combs, 2015, PloS one.

Amyloid-β oligomers stimulate microglia through a tyrosine kinase dependent mechanism

A. Floden, C. Combs, Gunjan Dhawan, 2012, Neurobiology of Aging.

Gut Inflammation Induced by Dextran Sulfate Sodium Exacerbates Amyloid-β Plaque Deposition in the AppNL - G - F Mouse Model of Alzheimer's Disease.

H. L. Pecoraro, C. Combs, Mona Sohrabi, 2021, Journal of Alzheimer's disease : JAD.

Inflammatory mechanisms in neurodegeneration

M. Tremblay, J. Neher, C. Combs, 2019, Journal of neurochemistry.

Amyloid precursor protein in pancreatic islets.

Joshua A. Kulas, C. Combs, K. Puig, 2017, The Journal of endocrinology.

Proinflammatory Chemical Signaling: Cytokines

C. Combs, K. Nagamoto-Combs, 2014 .

Pro-Inflammatory Responses in Human Monocytes are β1- Adrenergic Receptor Subtype Dependenta,b

E. Sauter, Laurel A. Grisanti, J. Porter, 2010 .

Bitter receptor TAS2R138 facilitates lipid droplet degradation in neutrophils during Pseudomonas aeruginosa infection

Min Wu, C. Combs, Zhihan Wang, 2021, Signal Transduction and Targeted Therapy.

Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition

A. Floden, C. Combs, Lalida Rojanathammanee, 2015, Journal of Neuroinflammation.

IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model

M. Klug, A. Floden, C. Combs, 2020, Frontiers in Cellular Neuroscience.

Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.

G. Landreth, D. Johnson, S. Cannady, 2000, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons

K. Herrup, D. Geldmacher, Qian Wu, 2000, Neurobiology of Aging.

β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis

G. Landreth, S. Kao, C. Combs, 2001, The Journal of Neuroscience.

β-Amyloid-Stimulated Microglia Induce Neuron Death via Synergistic Stimulation of Tumor Necrosis Factor α and NMDA Receptors

A. Floden, Shanshan Li, C. Combs, 2005, The Journal of Neuroscience.

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

G. Landreth, S. Kao, C. Combs, 2001, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Inflammation and Microglia Actions in Alzheimer’s Disease

C. Combs, 2009, Journal of Neuroimmune Pharmacology.

Particulate Matter Exposure Exacerbates Amyloid-β Plaque Deposition and Gliosis in APP/PS1 Mice.

L. Wold, A. Floden, C. Combs, 2021, Journal of Alzheimer's disease : JAD.

Exploiting Microglial Functions for the Treatment of Glioblastoma.

Pierluigi Navarra, L. Tentori, C. Dello Russo, 2017, Current cancer drug targets.

Amyloid Precursor Protein Expression Modulates Intestine Immune Phenotype

M. Sens, X. Zhou, C. Combs, 2012, Journal of Neuroimmune Pharmacology.

Mechanisms of Microglial Activation by Amyloid Precursor Protein and its Proteolytic Fragments

C. Combs, S. Austin, 2008 .

Anti-α4β1 Integrin Antibodies Attenuated Brain Inflammatory Changes in a Mouse Model of Alzheimer’s Disease

C. Combs, K. Puig, Gunjan D Manocha, 2018, Current Alzheimer research.

β-Amyloid Stimulates Murine Postnatal and Adult Microglia Cultures in a Unique Manner

A. Floden, C. Combs, 2006, The Journal of Neuroscience.

APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease

Brett A. McGregor, Joshua A. Kulas, D. Darland, 2016, The Journal of Neuroscience.

Modulation of Inflammatory Cytokines and Mitogen-activated Protein Kinases by Acetate in Primary Astrocytes

C. Combs, T. A. Rosenberger, Mahmoud L. Soliman, 2012, Journal of Neuroimmune Pharmacology.

Acetate reduces microglia inflammatory signaling in vitro

C. Combs, K. Puig, T. A. Rosenberger, 2012, Journal of neurochemistry.

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease

C. Combs, Gunjan Dhawan, Colin K Combs, 2012, Journal of Neuroinflammation.

Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues.

G. Taglialatela, Joshua A. Kulas, S. Barger, 2019, American journal of physiology. Endocrinology and metabolism.

Prolonged microgliosis in the rhesus monkey central nervous system after traumatic brain injury.

David W. McNeal, R. Morecraft, D. McNeal, 2007, Journal of neurotrauma.

Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition

A. Floden, C. Combs, Lalida Rojanathammanee, 2015, Journal of Neuroinflammation.

β-Amyloid Fibrils Activate Parallel Mitogen-Activated Protein Kinase Pathways in Microglia and THP1 Monocytes

Douglas R. McDonald, G. Landreth, C. Combs, 1998, The Journal of Neuroscience.

Impact of modulating gut bacteria using antibiotic, probiotic, and prebiotic interventions in the APPNL‐G‐F mouse model of Alzheimer disease

H. Kaur, C. Combs, K. Nagamoto-Combs, 2020, Alzheimer's & Dementia.

Expression of mutant alpha-synuclein modulates microglial phenotype in vitro

C. Combs, E. Murphy, Lalida Rojanathammanee, 2011, Journal of Neuroinflammation.

Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists

G. Landreth, S. Cannady, C. Combs, 2000, The Journal of Neuroscience.

Getting to the Heart of Alzheimer Disease

L. Wold, F. del Monte, C. Combs, 2019, Circulation research.

Long-term gliosis and molecular changes in the cervical spinal cord of the rhesus monkey after traumatic brain injury.

R. Morecraft, W. Darling, C. Combs, 2010, Journal of neurotrauma.

Regulation of β-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor α

G. Landreth, C. Combs, P. Bates, 2001, Neurochemistry International.

Lack of Alpha-Synuclein Modulates Microglial Phenotype In Vitro

M. Golovko, C. Combs, E. Murphy, 2011, Neurochemical Research.

An improved approach to align and embed multiple brain samples in a gelatin-based matrix for simultaneous histological processing

Kumi Nagamoto-Combs, Gunjan D. Manocha, Kendra Puig, 2016, Journal of Neuroscience Methods.

Tumor necrosis factor alpha stimulates NMDA receptor activity in mouse cortical neurons resulting in ERK‐dependent death

Brij B. Singh, J. H. Jara, A. Floden, 2007, Journal of neurochemistry.

b-Amyloid Fibrils Activate Parallel Mitogen-Activated Protein Kinase Pathways in Microglia and THP 1 Monocytes

Douglas R. McDonald, G. Landreth, C. Combs, 1998 .

Differential ability of a thiazolidinedione PPARγ agonist to attenuate cytokine secretion in primary microglia and macrophage‐like cells

C. Combs, Andrew P. Woster, 2007, Journal of neurochemistry.

α-Synuclein Expression Modulates Microglial Activation Phenotype

Colin K. Combs, Eric J. Murphy, A. Floden, 2006, The Journal of Neuroscience.

Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice

C. Scherzer, A. Floden, C. Combs, 2017, Molecular Neurodegeneration.

EFFECTS OF DEXTRAN SULFATE SODIUM-INDUCED COLITIS ON A MOUSE MODEL OF ALZHEIMER’S DISEASE

C. Combs, Mona Sohrabi, 2018, Alzheimer's & Dementia.

Activation of Neurotensin Receptor 1 Facilitates Neuronal Excitability and Spatial Learning and Memory in the Entorhinal Cortex: Beneficial Actions in an Alzheimer's Disease Model

E. Wada, F. Lesage, S. Lei, 2014, The Journal of Neuroscience.

Reactive Macrophages Increase Oxidative Stress and Alpha-Synuclein Nitration During Death of Dopaminergic Neuronal Cells in Co-Culture: Relevance to Parkinson’s Disease

M. Ebadi, C. Combs, S. Shavali, 2005, Neurochemical Research.

Tremor quantification of Parkinson's disease - a pilot study

Kouhyar Tavakolian, Reza Fazel-Rezai, Md Nafiul Alam, 2016, 2016 IEEE International Conference on Electro Information Technology (EIT).

A Quantitative Assessment of Bradykinesia Using Inertial Measurement Unit

Kouhyar Tavakolian, Reza Fazel-Rezai, Ajay K. Verma, 2017 .

Modulation of Inflammatory Cytokines and Mitogen-activated Protein Kinases by Acetate in Primary Astrocytes

C. Combs, T. A. Rosenberger, Mahmoud L. Soliman, 2013, Journal of Neuroimmune Pharmacology.

Liver Bile Acid Changes in Mouse Models of Alzheimer’s Disease

M. Golovko, C. Combs, Harpreet Kaur, 2021, International journal of molecular sciences.

The conformational epitope for a new Aβ42 protofibril‐selective antibody partially overlaps with the peptide N‐terminal region

Joshua A. Kulas, C. Combs, Benjamin A Colvin, 2017, Journal of neurochemistry.

Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer’s Disease in AppNL-G-F Mice

C. Combs, Harpreet Kaur, Suba Nookala, 2023, International journal of molecular sciences.

IL-6 Deficiency Exacerbates Allergic Asthma and Abrogates the Protective Effect of Allergic Inflammation against Streptococcus pneumoniae Pathogenesis

Min Wu, Sumit Ghosh, Ganesh Ambigapathy, 2020, The Journal of Immunology.

In utero exposure to fine particulate matter results in an altered neuroimmune phenotype in adult mice.

L. Wold, Joshua A. Kulas, M. P. McDonald, 2018, Environmental pollution.