D. Lane

发表

Iron and Alzheimer's Disease: An Update on Emerging Mechanisms.

Scott Ayton, Ashley I Bush, A. Bush, 2018, Journal of Alzheimer's disease : JAD.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

The Glutamate Aspartate Transporter (GLAST) Mediates l-Glutamate-Stimulated Ascorbate-Release Via Swelling-Activated Anion Channels in Cultured Neonatal Rodent Astrocytes

D. Lane, A. Lawen, Darius J. R. Lane, 2012, Cell Biochemistry and Biophysics.

The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways*

D. Richardson, D. Kalinowski, S. Sahni, 2015, The Journal of Biological Chemistry.

Ferroptosis and NRF2: an emerging battlefield in the neurodegeneration of Alzheimer's disease.

A. Bush, S. Ayton, D. Lane, 2021, Essays in biochemistry.

Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT).

D. Richardson, D. Kalinowski, S. Sahni, 2016, Biochimica et biophysica acta.

A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation.

D. Lane, A. Lawen, 2008, Analytical biochemistry.

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties

D. Richardson, K. Vávrová, D. Kalinowski, 2014, PloS one.

William Hunter and radioiodination: Revolutions in the labelling of proteins with radionuclides of iodine

D. Richardson, D. Lane, 2011 .

The old and new biochemistry of polyamines.

D. Richardson, P. Jansson, D. Lane, 2018, Biochimica et biophysica acta. General subjects.

A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane.

S. Robinson, Hania Czerwinska, D. Lane, 2010, The Biochemical journal.

A rapid and specific microplate assay for the determination of intra- and extracellular ascorbate in cultured cells.

D. Lane, A. Lawen, 2014, Journal of visualized experiments : JoVE.

Ascorbate and plasma membrane electron transport--enzymes vs efflux.

D. Lane, A. Lawen, 2009, Free radical biology & medicine.

Transplasma membrane electron transport comes in two flavors

D. Lane, A. Lawen, 2008 .

Transplasma membrane electron transport comes in two flavors.

D. Lane, A. Lawen, 2008, BioFactors.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Bonnie and Clyde: Vitamin C and iron are partners in crime in iron deficiency anaemia and its potential role in the elderly

D. Richardson, P. Jansson, D. Lane, 2016, Aging.

Non-transferrin Iron Reduction and Uptake Are Regulated by Transmembrane Ascorbate Cycling in K562 Cells*

D. Lane, A. Lawen, 2008, Journal of Biological Chemistry.

Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism.

D. Richardson, D. Lane, Sherin Chikhani, 2013, Biochimica et biophysica acta.

REVIEW Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich’s ataxia

D. Richardson, D. Lane, M. Huang, 2014 .

Making a case for albumin – a highly promising drug-delivery system.

D. Richardson, D. Kalinowski, S. Sahni, 2015, Future medicinal chemistry.

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics.

T. Ganz, D. Richardson, S. Toyokuni, 2016, Biochimica et biophysica acta.

The active role of vitamin C in mammalian iron metabolism: much more than just enhanced iron absorption!

D. Richardson, D. Lane, 2014, Free radical biology & medicine.

Letter to the Editor: “Analysis of the Interaction of Dp44mT with Human Serum Albumin and Calf Thymus DNA Using Molecular Docking and Spectroscopic Techniques”

D. Richardson, D. Kalinowski, S. Sahni, 2016, International journal of molecular sciences.

Novel Mechanism of Cytotoxicity for the Selective Selenosemicarbazone, 2-Acetylpyridine 4,4-Dimethyl-3-selenosemicarbazone (Ap44mSe): Lysosomal Membrane Permeabilization.

D. Richardson, D. Kalinowski, S. Sahni, 2016, Journal of medicinal chemistry.

Exploiting Cancer Metal Metabolism using Anti-Cancer Metal- Binding Agents.

D. Richardson, D. Kalinowski, S. Sahni, 2019, Current medicinal chemistry.

Duodenal Cytochrome b (DCYTB) in Iron Metabolism: An Update on Function and Regulation

D. Richardson, S. Sahni, D. Lane, 2015, Nutrients.

Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases

C. Pantelis, A. Bush, B. Moffat, 2021, Frontiers in Neuroscience.

Expanding horizons in iron chelation and the treatment of cancer: role of iron in the regulation of ER stress and the epithelial-mesenchymal transition.

D. Richardson, D. Kalinowski, N. Shafie, 2014, Biochimica et biophysica acta.

The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones.

D. Richardson, D. Kalinowski, S. Sahni, 2015, Pharmacological research.

Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool.

D. Richardson, D. Kalinowski, J. Kwagyan, 2013, Journal of inorganic biochemistry.

Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells

D. Hibbs, M. Doddareddy, D. Richardson, 2015, Oncotarget.

Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron.

S. Robinson, Hania Czerwinska, G. Bishop, 2010, The Biochemical journal.

Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol

D. Richardson, P. Ponka, A. Sheftel, 2010, Proceedings of the National Academy of Sciences.

Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling.

D. Richardson, D. Kalinowski, A. M. Merlot, 2016, Biochimica et biophysica acta.

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.

D. Richardson, K. Park, D. Kalinowski, 2012, Biochimica et biophysica acta.

Ascorbate and Tumor Cell Iron Metabolism: The Evolving Story and its Link to Pathology.

D. Richardson, D. Kalinowski, P. Jansson, 2020, Antioxidants & redox signaling.

The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targets

M. Zheng, D. Richardson, Zhihai Peng, 2015, Oncotarget.

Frataxin and the molecular mechanism of mitochondrial iron-loading in Friedreich's ataxia.

D. Richardson, D. Kalinowski, S. Sahni, 2016, Clinical science.

Turning the gun on cancer: Utilizing lysosomal P-glycoprotein as a new strategy to overcome multi-drug resistance.

D. Richardson, N. Seebacher, P. Jansson, 2016, Free radical biology & medicine.

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.

D. Richardson, Yu Yu, D. Kalinowski, 2016, Biochemical pharmacology.

Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics.

D. Richardson, K. Park, D. Kalinowski, 2016, Metallomics : integrated biometal science.

VDAC1 Is a Transplasma Membrane NADH-Ferricyanide Reductase*

V. De Pinto, M. Baker, J. Ly, 2004, Journal of Biological Chemistry.

Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action.

D. Lane, A. Lawen, 2013, Antioxidants & redox signaling.

N-myc Downstream Regulated 1 (NDRG1) Is Regulated by Eukaryotic Initiation Factor 3a (eIF3a) during Cellular Stress Caused by Iron Depletion

D. Richardson, F. Saletta, Z. Kovacevic, 2013, PloS one.

Tumor stressors induce two mechanisms of intracellular P-glycoprotein–mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones

D. Richardson, K. Park, S. Sahni, 2018, The Journal of Biological Chemistry.

The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1

M. Zheng, D. Richardson, D. Kalinowski, 2015, Oncotarget.

Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

D. Richardson, Y. Suryo Rahmanto, R. Casero, 2018, Biochimica et biophysica acta. Molecular basis of disease.

Mitochondrial mayhem: the mitochondrion as a modulator of iron metabolism and its role in disease.

D. Richardson, D. Lane, M. Huang, 2011, Antioxidants & redox signaling.

Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.

D. Richardson, D. Kalinowski, S. Sahni, 2015, Biochimica et biophysica acta.

Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich's ataxia

D. Richardson, D. Lane, A. Anzovino, 2014, British journal of pharmacology.

Biochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxia.

D. Richardson, D. Lane, M. Huang, 2013, The Biochemical journal.

The Metastasis Suppressor, N-myc Downstream-regulated Gene 1 (NDRG1), Inhibits Stress-induced Autophagy in Cancer Cells

D. Richardson, D. Kalinowski, S. Sahni, 2014, The Journal of Biological Chemistry.

Transcriptional regulation of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by the chelator, Dp44mT.

D. Richardson, Z. Kovacevic, D. Lane, 2017, Biochimica et biophysica acta. General subjects.

Glutathione S-transferase and MRP1 form an integrated system involved in the storage and transport of dinitrosyl-dithiolato iron complexes in cells.

D. Richardson, D. Kalinowski, S. Sahni, 2014, Free radical biology & medicine.

Can we target the a2-macroglobulin-hepcidin interaction to treat pathologic hypoferremia? "The advent of a new range of hepcidin therapeutics may now just be a matter of time."

D. Lane, 2014 .

Can we target the α2-macroglobulin-hepcidin interaction to treat pathologic hypoferremia?

D. Richardson, D. Lane, 2014, Future medicinal chemistry.

Melanotransferrin Functions as a Pro-Oncogenic WNT Agonist: A Yin-Yang Relationship in Melanoma with the WNT Antagonist and Metastasis Suppressor, NDRG1

J. Wilmott, X. Zhao, D. Richardson, 2023, bioRxiv.

Voltage-dependent anion-selective channel 1 (VDAC1)--a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane.

A. Messina, V. De Pinto, K. Zarschler, 2005, The international journal of biochemistry & cell biology.

IRON METABOLISM AND AUTOPHAGY: A POORLY EXPLORED RELATIONSHIP THAT HAS IMPORTANT CONSEQUENCES FOR HEALTH AND DISEASE

D. Richardson, S. Sahni, P. Jansson, 2015, Nagoya journal of medical science.

Acireductone dioxygenase 1 (ADI1) is regulated by cellular iron by a mechanism involving the iron chaperone, PCBP1, with PCBP2 acting as a potential co-chaperone.

D. Richardson, R. Sutak, P. Jansson, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression.

D. Richardson, D. Lane, M. Huang, 2013, The Biochemical journal.

Nitrogen Monoxide (NO) Storage and Transport by Dinitrosyl-Dithiol-Iron Complexes: Long-lived NO That Is Trafficked by Interacting Proteins*

D. Richardson, Y. Suryo Rahmanto, D. Kalinowski, 2012, The Journal of Biological Chemistry.

Neuropathological Mechanisms of β-N-Methylamino-L-Alanine (BMAA) with a Focus on Iron Overload and Ferroptosis

A. Bush, Hamed Kazemi Shariat Panahi, G. Guillemin, 2022, Neurotoxicity Research.

Glucose Modulation Induces Lysosome Formation and Increases Lysosomotropic Drug Sequestration via the P-Glycoprotein Drug Transporter*

D. Richardson, N. Seebacher, P. Jansson, 2015, The Journal of Biological Chemistry.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Frataxin, a molecule of mystery: trading stability for function in its iron-binding site.

D. Richardson, D. Lane, 2010, The Biochemical journal.

The Glutamate Aspartate Transporter (GLAST) Mediates l-Glutamate-Stimulated Ascorbate-Release Via Swelling-Activated Anion Channels in Cultured Neonatal Rodent Astrocytes

D. Lane, A. Lawen, 2013, Cell Biochemistry and Biophysics.

Chaperone turns gatekeeper: PCBP2 and DMT1 form an iron-transport pipeline.

D. Richardson, D. Lane, 2014, The Biochemical journal.

The lure of a LYR: The logistics of iron sulfur cluster delivery.

D. Lane, A. Merlot, Des R. Richardson, 2014, Cell metabolism.