A. Galeone

发表

MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma

Giuseppe Basso, Achille Iolascon, Giuseppe Cinalli, 2011, PloS one.

Synthesis and characterization of DNA quadruplexes containing T‐tetrads formed by bunch‐oligonucleotides

G. Piccialli, Jussara Amato, L. Mayol, 2006, Biopolymers.

Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution

G. Piccialli, L. Mayol, A. Galeone, 2004 .

Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG2T(G3T)3] and Its Derivatives with an Abasic Site Replacing Single Thymidine

A. Russo, G. Russo, A. Galeone, 2021, International journal of molecular sciences.

Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923

L. Mayol, A. Pepe, E. Tramontano, 2020, International journal of molecular sciences.

Backbone modified TBA analogues endowed with antiproliferative activity.

A. Russo, G. Russo, A. Galeone, 2017, Biochimica et biophysica acta. General subjects.

More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures.

L. Mayol, A. Galeone, A. Virgilio, 2014, Organic & biomolecular chemistry.

A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract.

L. Mayol, A. Randazzo, A. Galeone, 2008, Molecular bioSystems.

Solution Structure of the Head-to-Head Dimer of Calicheamicin Oligosaccharide Domain and d(CGTAGGATATCCTACG) 2

G. Bifulco, K. Nicolaou, W. Chazin, 1996 .

Solution Structure of the Complex between the Head-to-Tail Dimer of Calicheamicin Gamma-1-I Oligosaccharide and a DNA Duplex Containing D(Acct) and D(Tcct) High-Affinity Binding Sites

G. Bifulco, K. Nicolaou, W. Chazin, 1998 .

Structural Model of the hUbA1-UbcH10 Quaternary Complex: In Silico and Experimental Analysis of the Protein-Protein Interactions between E1, E2 and Ubiquitin

A. Fusco, B. Catalanotti, E. Pedone, 2014, PloS one.

A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance.

L. Mayol, A. Galeone, A. Virgilio, 2014, Organic & biomolecular chemistry.

Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites

L. Mayol, A. Galeone, A. Virgilio, 2015 .

Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine.

L. Mayol, A. Randazzo, A. Galeone, 2004, Bioorganic & medicinal chemistry.

1H-NMR Study of the Quadruplex [d(TGGGT)]4 Containing a Modified Thymine

G. Barone, C. Giancola, L. Mayol, 2003, Nucleosides, nucleotides & nucleic acids.

Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides.

L. Mayol, A. Galeone, A. Virgilio, 2011, Biochimie.

uL3 Mediated Nucleolar Stress Pathway as a New Mechanism of Action of Antiproliferative G-quadruplex TBA Derivatives in Colon Cancer Cells

A. Russo, G. Russo, A. Galeone, 2020, Biomolecules.

Biophysical properties of quadruple helices of modified human telomeric DNA

G. Barone, C. Giancola, A. Randazzo, 2005, Biopolymers.

Circular dichroism and thermal melting differentiation of Hoechst 33258 binding to the curved (A4T4) and straight (T4A4) DNA sequences

B. Catalanotti, C. Canzonetta, A. Scipioni, 2002 .

Solid-phase synthesis of oligonucleotides containing a bipyridine ligand at the 3'-3' inversion of polarity site.

L. Mayol, A. Galeone, G. Oliviero, 2001, Bioorganic & medicinal chemistry letters.

The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures.

C. Giancola, L. Mayol, A. Galeone, 2015, Organic & biomolecular chemistry.

Tetra-end-linked oligonucleotides forming DNA G-quadruplexes: a new class of aptamers showing anti-HIV activity.

G. Piccialli, S. Haider, J. Balzarini, 2010, Chemical communications.

Novel monomolecular derivatives of the anti-HIV-1 G-quadruplex-forming Hotoda's aptamer containing inversion of polarity sites.

S. Richter, M. Nadai, A. Galeone, 2020, European journal of medicinal chemistry.

Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence.

G. Tell, D. Marasco, B. Demple, 2019, DNA repair.

On the connection between inherent DNA flexure and preferred binding of hydroxymethyluracil-containing DNA by the type II DNA-binding protein TF1.

E. Geiduschek, L. Mayol, A. Galeone, 1996, Journal of molecular biology.

Antiproliferative Effects of the Aptamer d(GGGT)4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer Cells

A. Russo, G. Russo, A. Galeone, 2022, International journal of molecular sciences.

Effect of gamma-hydroxypropano deoxyguanosine, the major acrolein-derived adduct, on monomolecular quadruplex structure of telomeric repeat d(TTAGGG)(4).

G. Piccialli, L. Mayol, A. Galeone, 2004, Bioorganic & medicinal chemistry letters.

Ptaquiloside, the major carcinogen of bracken fern, in the pooled raw milk of healthy sheep and goats: an underestimated, global concern of food safety.

O. Taglialatela‐Scafati, A. Galeone, A. Virgilio, 2015, Journal of agricultural and food chemistry.

Synthesis of a New N1‐Pentyl Analogue of Cyclic Inosine Diphosphate Ribose (cIDPR) as a Stable Potential Mimic of Cyclic ADP Ribose (cADPR)

G. Piccialli, L. Mayol, A. Galeone, 2002 .

Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer.

M. Zollo, Pasqualino de Antonellis, D. Spano, 2012, European journal of medicinal chemistry.

INTERACTION OF DISTAMYCIN A AND NETROPSIN WITH QUADRUPLEX AND DUPLEX STRUCTURES: A COMPARATIVE 1H-NMR STUDY

L. Mayol, A. Randazzo, A. Galeone, 2002, Nucleosides, nucleotides & nucleic acids.

1 H-NMR study of the interaction of distamycin A and netropsin with the parallel stranded tetraplex [d(TGGGGT)]4

L. Mayol, A. Randazzo, A. Galeone, 2001 .

Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads

E. Panza, D. Marasco, A. Galeone, 2022, International Journal of Molecular Sciences.

Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives

A. Russo, G. Russo, A. Pepe, 2020, Nucleic acids research.

Thrombin binding aptamer analogues containing inversion of polarity sites endowed with antiproliferative and anti-motility properties against Calu-6 cells.

A. Russo, G. Russo, L. Mayol, 2018, Biochimica et biophysica acta. General subjects.

The "Janus face" of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications.

A. Russo, G. Russo, L. Mayol, 2018, Bioorganic chemistry.

Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative

Nicola Borbone, Giuseppe Cirino, Elisa Rivieccio, 2015, Nucleic acids research.

Synthesis of two distamycin analogues and their binding mode to d(CGCAAATTTGCG)2 in the 2:1 solution complexes as determined by two-dimensional 1H-NMR.

M. Conte, L. Mayol, P. Lombardi, 1995, Journal of medicinal chemistry.

Automated solid phase synthesis of cyclic oligonucleotides: a further improvement.

G. Piccialli, L. Mayol, D. Montesarchio, 1995, Bioorganic & Medicinal Chemistry.

Facile preparation of cyclic oligoribonucleotides

G. Piccialli, L. Mayol, A. Messere, 1993 .

Solid phase synthesis of 5-hydroxymethyluracil containing DNA

V. Hsu, D. Avizonis, M. Conte, 1992 .

Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands.

Salvatore Florio, Francesco Paduano, Francesco Trapasso, 2011, Bioorganic & medicinal chemistry.

SOLID-PHASE SYNTHESIS OF CYCLIC OLIGODEOXYRIBONUCLEOTIDES : INTERMOLECULARVERSUS INTRAMOLECULAR COUPLING

G. Piccialli, D. Montesarchio, A. Messere, 1991 .

5‐Hydroxymethyl‐2′‐Deoxyuridine Residues in the Thrombin Binding Aptamer: Investigating Anticoagulant Activity by Making a Tiny Chemical Modification

L. Mayol, A. Galeone, A. Virgilio, 2014, Chembiochem : a European journal of chemical biology.

Effect of a modified thymine on the structure and stability of [d(TGGGT)]4 quadruplex.

G. Barone, C. Giancola, L. Mayol, 2003, International journal of biological macromolecules.

Affinity, stability and polarity of binding of the TATA binding protein governed by flexure at the TATA Box.

E. Geiduschek, L. Mayol, E. Yu, 1998, Journal of molecular biology.

Twin Hydroxymethyluracil-A Base Pair Steps Define the Binding Site for the DNA-bending Protein TF1*

E. Geiduschek, L. Mayol, M. Figueiredo, 1997, The Journal of Biological Chemistry.

Localized DNA flexibility contributes to target site selection by DNA-bending proteins.

E. Geiduschek, L. Mayol, A. Galeone, 1996, Journal of molecular biology.

1H NMR studies of the 5-(hydroxymethyl)-2'-deoxyuridine containing TF1 binding site.

J. Bramham, X. Jia, L. Mayol, 1996, Nucleic acids research.

Synthesis and characterisation of poly(D,L-lactic acid)-idoxuridine conjugate.

M. G. Rimoli, F. Forni, M. Vandelli, 1999, Journal of controlled release : official journal of the Controlled Release Society.

SYNTHESIS OF 5-METHYLAMINO-2′-DEOXYURIDINE DERIVATIVES

B. Catalanotti, L. Mayol, A. Galeone, 2001, Nucleosides, nucleotides & nucleic acids.

Syntheses of [1-15N]-2′-Deoxyinosine, [4-15N]-2′-DeoxyAICAR, and [1-15N]-2′-Deoxyguanosine

G. Piccialli, B. Catalanotti, L. Mayol, 1999 .

Studies on Alternate Strand Triple Helix Formation by Oligodeoxyribonucleotides Containing A 3′-3′ Phosphodiester Bond

G. Piccialli, L. Mayol, A. Pepe, 1998 .

Synthesis of a novel N-1 carbocyclic, N-9 butyl analogue of cyclic ADP ribose (cADPR)

G. Piccialli, L. Mayol, A. Galeone, 2002 .

Syntheses of [1-15N]-2′-Deoxyinosine, [4-15N]-2′-DeoxyAICAR, and [1-15N]-2′-Deoxyguanosine.

G. Piccialli, B. Catalanotti, L. Mayol, 1999 .

A novel pyrimidine tetrad contributing to stabilize tetramolecular G-quadruplex structures.

L. Mayol, A. Pepe, R. Filosa, 2016, Organic & biomolecular chemistry.

Thermodynamics of melting of the circular dumbbell d〈pCGC‐TT‐GCG‐TT〉

J. H. Ippel, J. Pikkemaat, L. Mayol, 1995 .

2'-Deoxy-8-(propyn-1-yl)adenosine-containing oligonucleotides: effects on stability of duplex and quadruplex structures.

B. Catalanotti, L. Gomez‐Paloma, L. Mayol, 2000, Bioorganic & medicinal chemistry letters.

Oligonucleotide delivery in cancer therapy

G. De Rosa, D. De Stefano, A. Galeone, 2010, Expert opinion on drug delivery.

MicroRNA-199b-5p Impairs Cancer Stem Cells through Negative Regulation of HES1 in Medulloblastoma

P. Northcott, O. Delattre, A. Brunetti, 2009, PloS one.

Metastatic group 3 medulloblastoma is driven by PRUNE1 targeting NME1–TGF-&bgr;–OTX2–SNAIL via PTEN inhibition

O. Delattre, F. Tirone, A. Brunetti, 2018, Brain : a journal of neurology.

Monomolecular G-quadruplex structures with inversion of polarity sites: new topologies and potentiality

A. Russo, G. Russo, L. Mayol, 2017, Nucleic acids research.

MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines

A. Falanga, G. Rosa, S. Galdiero, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

Structural Investigations on the Anti‐HIV G‐Quadruplex‐Forming Oligonucleotide TGGGAG and Its Analogues: Evidence for the Presence of an A‐Tetrad

L. Mayol, A. Galeone, A. Virgilio, 2012, Chembiochem : a European journal of chemical biology.

Synthesis of quadruplex‐forming tetra‐end‐linked oligonucleotides: Effects of the linker size on quadruplex topology and stability

G. Piccialli, Jussara Amato, L. Mayol, 2009, Biopolymers.

Aptamers Against the β-Conglutin Allergen: Insights into the Behavior of the Shortest Multimeric(Intra)Molecular DNA G-Quadruplex

Miriam Jauset-Rubio, M. Svobodová, T. Mairal, 2021, International journal of molecular sciences.

Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity

L. Mayol, A. Pepe, A. Galeone, 2015, Nucleic acids research.

Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide.

Nicola Borbone, Giuseppe Cirino, Giorgia Oliviero, 2008, Bioorganic & medicinal chemistry.

miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma

P. Tassone, P. Tagliaferri, M. Caraglia, 2019, Molecular therapy. Nucleic acids.

The abasic site lesions in the human telomeric sequence d[TA(G(3)T(2)A)(3)G(3)]: a thermodynamic point of view.

C. Giancola, A. Galeone, A. Virgilio, 2012, Biochimica et biophysica acta.

Transferrin-Conjugated SNALPs Encapsulating 2′-O-Methylated miR-34a for the Treatment of Multiple Myeloma

P. Tassone, P. Tagliaferri, M. Caraglia, 2014, BioMed research international.

Effect of the Introduction of an A-Residue into A Quadruplex Forming Oligonucleotide Containing A 5′-5′ Polarity of Inversion Site

L. Mayol, A. Randazzo, A. Galeone, 2007, Nucleosides, nucleotides & nucleic acids.

A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3'-3' or 5'-5' inversion of polarity site.

L. Mayol, A. Randazzo, A. Galeone, 2005, Chemical communications.

Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4.

Giuseppe Bifulco, Luigi Martino, Simone Di Micco, 2007, Journal of the American Chemical Society.

Design and NMR study of an immobile DNA four-way junction containing 38 nucleotides.

F. J. Overmars, J. Pikkemaat, L. Mayol, 1997, European journal of biochemistry.

Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide G-quadruplexes with double 3'-external G-quartets.

A. Galeone, A. Virgilio, D. Monchaud, 2019, International journal of biological macromolecules.

Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures

C. Giancola, L. Martino, L. Mayol, 2009, Nucleic acids research.

UNUSUAL MONOMOLECULAR DNA QUADRUPLEX STRUCTURES USING BUNCH-OLIGONUCLEOTIDES

G. Piccialli, L. Mayol, A. Galeone, 2005, Nucleosides, Nucleotides & Nucleic Acids.

A BUNCH-OLIGONUCLEOTIDE FORMING STABLE MONOMOLECULAR QUADRUPLEX CONTAINING A T-TETRAD

G. Piccialli, L. Mayol, A. Galeone, 2005, Nucleosides, Nucleotides & Nucleic Acids.

Synthesis and characterization of monomolecular DNA G-quadruplexes formed by tetra-end-linked oligonucleotides.

G. Piccialli, Jussara Amato, L. Mayol, 2006, Bioconjugate chemistry.

Synthesis and Characterization of Tetra-End Linked Oligonucleotides Capable of Forming Monomolecular G-Quadruplexes

G. Piccialli, Jussara Amato, L. Mayol, 2007, Nucleosides, nucleotides & nucleic acids.

Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway

E. Panza, A. Galeone, A. Virgilio, 2023, International journal of molecular sciences.

Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes

J. Plavec, A. Galeone, A. Virgilio, 2012, Nucleic acids research.

The insertion of two 8-methyl-2′-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands

L. Mayol, A. Pepe, A. Galeone, 2011, Nucleic acids research.

Exploring the binding of d(GGGT)4 to the HIV-1 integrase: An approach to investigate G-quadruplex aptamer/target protein interactions.

L. Mayol, E. Pedone, L. Pirone, 2016, Biochimie.

The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives.

L. Mayol, R. Filosa, A. Galeone, 2016, Mini reviews in medicinal chemistry.

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes.

J. Mergny, A. Galeone, A. Virgilio, 2011, Biochimie.

Effects of the introduction of inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT.

L. Mayol, A. Pepe, A. Galeone, 2009, Bioorganic & medicinal chemistry.

Investigating the properties of TBA variants with twin thrombin binding domains

E. Pedone, L. Pirone, A. Galeone, 2019, Scientific Reports.

Improved thrombin binding aptamer analogues containing inversion of polarity sites: structural effects of extra-residues at the ends.

L. Mayol, R. Filosa, A. Galeone, 2016, Organic & biomolecular chemistry.

8-Methyl-2′-deoxyguanosine incorporation into parallel DNA quadruplex structures

L. Mayol, A. Randazzo, A. Galeone, 2005, Nucleic acids research.

Effects of 8-methyl-2'-deoxyadenosine incorporation into quadruplex forming oligodeoxyribonucleotides.

L. Mayol, A. Randazzo, A. Galeone, 2005, Bioorganic & medicinal chemistry.

Conformation of the circular dumbbell d〈pCGC-TT-GCG-TT〉: Structure determination and molecular dynamics

J. H. Ippel, J. Pikkemaat, L. Mayol, 1995 .

An NMR study of the conformation and thermodynamics of the circular dumbbell d [formula: see text] Slow exchange between two- and four-membered hairpin loops.

J. H. Ippel, J. Pikkemaat, L. Mayol, 1992, Journal of biomolecular structure & dynamics.

Slow conformational exchange in DNA minihairpin loops: A conformationalstudy of the circular dumbbell d〈pCGC‐TT‐GCG‐TT〉

J. H. Ippel, J. Pikkemaat, L. Mayol, 1995 .

Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops

E. Novellino, I. Gomez-Monterrey, S. Haider, 2018, Scientific Reports.

A Topological Classification of G-Quadruplex Structures

L. Mayol, A. Galeone, A. Virgilio, 2007, Nucleosides, nucleotides & nucleic acids.

Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops

E. Novellino, I. Gomez-Monterrey, S. Haider, 2018, Scientific Reports.

A Mini-Library of TBA Analogues Containing 3′-3′ and 5′-5′ Inversion of Polarity Sites

L. Mayol, A. Randazzo, A. Galeone, 2007, Nucleosides, nucleotides & nucleic acids.

More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures.

L. Mayol, A. Galeone, A. Virgilio, 2014, Organic & biomolecular chemistry.

A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site.

L. Mayol, A. Galeone, A. Virgilio, 2013, Chemical communications.

G-triplex stability in human telomeric DNA with epigenetic modification/oxidative damage to thymine

M. Caterino, C. Giancola, A. Galeone, 2018, Journal of Thermal Analysis and Calorimetry.

Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction

A. Zampella, Carmen Festa, A. Galeone, 2022, International journal of molecular sciences.

PNA-DNA Chimeras Forming Quadruplex Structures

G. Piccialli, L. Mayol, A. Randazzo, 2003, Nucleosides, nucleotides & nucleic acids.