H. Griffin

发表

The Reservoir of Persistent Human Papillomavirus Infection; Strategies for Elimination Using Anti-Viral Therapies

J. Doorbar, Ke Zheng, N. Egawa, 2022, Viruses.

Mutations in HPV18 E1^E4 Impact Virus Capsid Assembly, Infectivity Competence, and Maturation

Margaret E McLaughlin-Drubin, C. Meyers, J. Doorbar, 2017, Viruses.

Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples

J. Doorbar, K. Cuschieri, K. Kavanagh, 2018, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Title : Stratification of HPV-Induced Cervical Pathology using the Virally-Encoded Molecular Marker E 4 in Combination with p 16 and MCM

W. Quint, A. Singer, R. Jach, 2015 .

Role of E6 in Maintaining the Basal Cell Reservoir during Productive Papillomavirus Infection

Ke-Jia Zheng, J. Doorbar, N. Egawa, 2022, Journal of virology.

Delta-Like Ligand–Notch1 Signaling Is Selectively Modulated by HPV16 E6 to Promote Squamous Cell Proliferation and Correlates with Cervical Cancer Prognosis

G. Kenter, R. D. de Menezes, J. Doorbar, 2021, Cancer Research.

Title : Investigating Diagnostic Problems of CIN 1 and 2 Associated with High-Risk HPV by Combining the Novel Molecular Biomarker PanHPV E 4 with P 16 ink 4 a

Wim, H. Huras, K. Okoń, 2015 .

Characterization of events during the late stages of HPV16 infection in vivo using high-affinity synthetic Fabs to E4.

S. Napthine, G. Winter, N. Coleman, 1997, Virology.

The E1 (cid:217) E4 Protein of Human Papillomavirus Type 16 Associates with a Putative RNA Helicase through Sequences in Its C Terminus

R. Elston, S. Stacey, S. Napthine, 2000 .

Principles of epithelial homeostasis control during persistent human papillomavirus infection and its deregulation at the cervical transformation zone.

Yuwen Chen, J. Doorbar, N. Egawa, 2021, Current opinion in virology.

E6AP is important for HPV E6’s role in regulating epithelial homeostasis and its loss impairs keratinocyte commitment to differentiation

Ke-Jia Zheng, J. Doorbar, N. Egawa, 2022, bioRxiv.

Refining our understanding of cervical neoplasia and its cellular origins

J. Doorbar, H. Griffin, 2019, Papillomavirus research.

Investigating Diagnostic Problems of CIN1 and CIN2 Associated With High-risk HPV by Combining the Novel Molecular Biomarker PanHPVE4 With P16INK4a

W. Quint, R. Jach, H. Huras, 2015, The American journal of surgical pathology.

Human papillomavirus molecular biology and disease association

J. Doorbar, N. Egawa, H. Griffin, 2015, Reviews in medical virology.

Functional Analysis of the Human Papillomavirus Type 16 E1∧E4 Protein Provides a Mechanism for In Vivo and In Vitro Keratin Filament Reorganization

P. McIntosh, M. Omary, P. Walker, 2004, Journal of Virology.

Human Papillomaviruses; Epithelial Tropisms, and the Development of Neoplasia

K. Egawa, J. Doorbar, N. Egawa, 2015, Viruses.

E4 Antibodies Facilitate Detection and Type-Assignment of Active HPV Infection in Cervical Disease

W. Quint, C. van Hoof, F. Struyf, 2012, PloS one.

Structural Analysis Reveals an Amyloid Form of the Human Papillomavirus Type 16 E1∧E4 Protein and Provides a Molecular Basis for Its Accumulation

P. McIntosh, K. Raj, J. Eccleston, 2008, Journal of Virology.

Whole tissue cervical mapping of HPV infection: Molecular evidence for focal latent HPV infection in humans

W. Quint, H. Svanholm, J. Doorbar, 2019, Papillomavirus research.

Organization of Human Papillomavirus Productive Cycle during Neoplastic Progression Provides a Basis for Selection of Diagnostic Markers

Lesley Morris, Nicholas Coleman, P. Lambert, 2003, Journal of Virology.

Intrabody strategies for the treatment of human papillomavirus-associated disease

J. Doorbar, H. Griffin, 2007, Expert opinion on biological therapy.

Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy

Mark M. Davis, J. Casanova, L. Notarangelo, 2021, Cell.

Inhibition of papillomavirus protein function in cervical cancer cells by intrabody targeting.

R. Elston, G. Winter, J. Doorbar, 2006, Journal of molecular biology.

Modulation of basal cell fate during productive and transforming HPV‐16 infection is mediated by progressive E6‐driven depletion of Notch

R. Mahmood, J. Doorbar, H. Griffin, 2017, The Journal of pathology.

The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions

M. Feltkamp, G. Inman, C. Proby, 2018, Front. Microbiol..

Human Papillomavirus type 16 Causes a Defined Subset of Conjunctival In Situ Squamous Cell Carcinomas

W. Quint, R. Mahmood, I. Rennie, 2019, Modern Pathology.

The E1∧E4 Protein of Human Papillomavirus Type 16 Associates with a Putative RNA Helicase through Sequences in Its C Terminus

R. Elston, S. Stacey, S. Napthine, 2000, Journal of Virology.

Roles for E1-independent replication and E6-mediated p53 degradation during low-risk and high-risk human papillomavirus genome maintenance

T. Kiyono, J. Doorbar, Tomomi Nakahara, 2019, PLoS pathogens.

HPV16 and 18 genome amplification show different E4-dependence, with 16E4 enhancing E1 nuclear accumulation and replicative efficiency via its cell cycle arrest and kinase activation functions

R. Mahmood, J. Doorbar, N. Egawa, 2017, PLoS pathogens.

Stratification of HPV-Induced Cervical Pathology using the Virally-Encoded Molecular Marker E4 in Combination with p16 or MCM

W. Quint, A. Singer, R. Jach, 2015, Modern Pathology.

Inhibition of E6-induced degradation of its cellular substrates by novel blocking peptides.

R. Elston, P. McIntosh, L. Banks, 2004, Journal of molecular biology.

Characterization of beta papillomavirus E4 expression in tumours from Epidermodysplasia Verruciformis patients and in experimental models.

H. Pfister, S. Landolfo, J. Doorbar, 2012, Virology.

Restoration of the LFA‐3 adhesion pathway in Burkitt's lymphoma cells using an LFA‐3 recombinant vaccinia virus: consequences for T cell recognition

M. Rowe, A. Rickinson, J. Brooks, 1992, European journal of immunology.

The early detection of cervical cancer. The current and changing landscape of cervical disease detection

R. Crawford, J. Doorbar, N. Egawa, 2020, Cytopathology : official journal of the British Society for Clinical Cytology.

Identification of the skin virome in a boy with widespread human papillomavirus‐2‐positive warts that completely regressed after administration of tetravalent human papillomavirus vaccine

F. Mignone, A. Matteelli, J. Doorbar, 2015, The British journal of dermatology.

Identification of the skin virome in a young boy with widespread HPV2-positive warts that completely regressed after administration of tetravalent human papillomavirus vaccine Running title: HPV2 variant in warts and vaccine outcome

F. Mignone, A. Matteelli, J. Doorbar, 2022 .

Cervical cell lift: A novel triage method for the spatial mapping and grading of precancerous cervical lesions

P. Sasieni, R. Crawford, J. Doorbar, 2022, EBioMedicine.

Reconstruction of Human Papillomavirus Type 16-Mediated Early-Stage Neoplasia Implicates E6/E7 Deregulation and the Loss of Contact Inhibition in Neoplastic Progression

N. Coleman, I. Roberts, J. Doorbar, 2012, Journal of Virology.

E1^E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epithelium

P. McIntosh, J. Doorbar, H. Griffin, 2010, Journal of Cell Science.

HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation

Ke-Jia Zheng, J. Doorbar, N. Egawa, 2023, PLoS pathogens.