Jaewhan Song

发表

Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer

S. Hewitt, Jae-seok Roe, Joon-Yong Chung, 2019, Cell Death & Differentiation.

The roles of ubiquitination in extrinsic cell death pathways and its implications for therapeutics.

K. Bae, Sang Chul Lee, Jaewhan Song, 2019, Biochemical pharmacology.

Functional genomics approach using mice.

Han-Woong Lee, Han-Woong Lee, Young Hoon Sung, 2004, Journal of biochemistry and molecular biology.

Jab1 as a mediator of nuclear export and cytoplasmic degradation of p53.

Jaewhan Song, Eun-Woo Lee, W. Oh, 2006, Molecules and cells.

PML-IV functions as a negative regulator of telomerase by interacting with TERT

Eui Tae Kim, Jaewang Ghim, Jin-Hyun Ahn, 2009, Journal of Cell Science.

Oleanolic acid regulates NF-κB signaling by suppressing MafK expression in RAW 264.7 cells

Kyung-A Hwang, Jaewhan Song, Yu-Jin Hwang, 2014, BMB reports.

Post-Translational Regulation of ARF: Perspective in Cancer

D. Oh, Jaewhan Song, Jinho Seo, 2020, Biomolecules.

Necroptosis molecular mechanisms: Recent findings regarding novel necroptosis regulators

D. Oh, Jaewhan Song, Jinho Seo, 2021, Experimental & Molecular Medicine.

Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex

P. Vandenabeele, Han-Woong Lee, Young-June Jin, 2020, Cell Death & Differentiation.

Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Y. Ahn, D. H. Kim, Kyoung-Jin Oh, 2019, Cell Death & Disease.

MafK positively regulates NF-kB activity by enhancing CBP-mediated p65

Kyung-A Hwang, Jaewhan Song, Haeng-Ran Kim, 2013 .

Jab1 has negative effects on p53-mediated genotoxic stresses.

Sangsik Lee, Jaewhan Song, Eun-Woo Lee, 2009, BMB reports.

Deubiquitinases: Modulators of Different Types of Regulated Cell Death

Seungyeon Kim, Jaewhan Song, Choong-Sil Lee, 2021, International journal of molecular sciences.

Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.

S. Hewitt, Soo-Youl Kim, C. Choi, 2017, Cancer research.

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

S. Hewitt, Joon-Yong Chung, Hanbyoul Cho, 2015, Nature Communications.

Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC

Soo-Youl Kim, Soohyung Lee, Jaewhan Song, 2018, Scientific Reports.

Regulatory Network of ARF in Cancer Development

Jaewhan Song, S. Han, A. Ko, 2018, Molecules and cells.

Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF

S. Hewitt, Soo-Youl Kim, C. Choi, 2018, Cell Death & Differentiation.

Targeting the WEE1 kinase as a molecular targeted therapy for gastric cancer

Seok-Jun Kim, Jaewhan Song, Kyung-Hee Chun, 2016, Oncotarget.

Dynamics of ARF regulation that control senescence and cancer

Jaewhan Song, S. Han, A. Ko, 2016, BMB reports.

CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3

P. Vandenabeele, J. Seong, Cheolju Lee, 2016, Nature Cell Biology.

K6 linked polyubiquitylation of FADD by CHIP prevents death inducing signaling complex formation suppressing cell death

Cheolju Lee, Jaewhan Song, Jinho Seo, 2018, Oncogene.

Cytoplasmic MYC is an anti-necroptotic protein

Jaewhan Song, Eun-Woo Lee, D. Seong, 2020, Molecular & cellular oncology.

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells.

Jae-Ho Kim, Younghun Kim, Sang-Wook Kim, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

Differentiation of West Nile virus-infected animals from vaccinated animals by competitive ELISA using monoclonal antibodies against non-structural protein 1.

K. Chung, Jaewhan Song, J. Yeh, 2012, Vector borne and zoonotic diseases.

Galectin-3 activates PPARγ and supports white adipose tissue formation and high-fat diet-induced obesity.

Seok-Jun Kim, Kyung-A Hwang, Jaewhan Song, 2015, Endocrinology.

Hematopoietic malignancies associated with increased Stat5 and Bcl-x L expressions in Ink4a/Arf-deficient mice

Han-Woong Lee, S. Park, C. Cheong, 2005, Mechanisms of Ageing and Development.

Hsp70 functions as a negative regulator of West Nile virus capsid protein through direct interaction

Jaewhan Song, W. Oh, 2006, Biochemical and Biophysical Research Communications.

Targeting Oxidative Phosphorylation Reverses Drug Resistance in Cancer Cells by Blocking Autophagy Recycling

Soo-Youl Kim, H. Jang, S. Woo, 2020, Cells.

Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF

I. Choi, Han-Woong Lee, Ji‐Young Shin, 2012, Journal of the National Cancer Institute.

Acceleration of Gastric t umorigenesis t hrough MK r N1-Mediated Posttranslational r egulation of p14A r F

I. Choi, Ji‐Young Shin, M. Lee, 2012 .

Role of INK4a locus in normal eye development and cataract genesis

Han-Woong Lee, C. Kee, C. Cheong, 2006, Mechanisms of Ageing and Development.

Non-Hodgkin Lymphoma Occurred in Psoas Muscle

Jaewhan Song, J. Kim, Jin Kim, 2013 .

The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in metabolism, immunity, and cancer

K. Park, Jaewhan Song, Jung-Hoon Kim, 2015, Archives of Pharmacal Research.

Identification of MYC as an antinecroptotic protein that stifles RIPK1–RIPK3 complex formation

P. Vandenabeele, A. Oberst, S. Ha, 2020, Proceedings of the National Academy of Sciences.

Anti-cancer effect of a quinoxaline derivative GK13 as a transglutaminase 2 inhibitor

Jaewhan Song, Y. Gong, Se-Jin Kim, 2013, Journal of Cancer Research and Clinical Oncology.

Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis

Han-Woong Lee, J. Ro, Seok-Jun Kim, 2012, Nature Communications.

Bag1 Functions In Vivo as a Negative Regulator of Hsp70 Chaperone Activity

H. Kampinga, R. Morimoto, E. Nollen, 2000, Molecular and Cellular Biology.

Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer.

Y. Huh, Kyoung-Jin Oh, K. Bae, 2020, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of translation and induction of apoptosis by Bunyaviral nonstructural proteins bearing sequence similarity to reaper.

Daniel A. Colón-Ramos, R. Morimoto, R. Hollingsworth, 2003, Molecular biology of the cell.

The roles of FADD in extrinsic apoptosis and necroptosis.

Sangsik Lee, Jaewhan Song, Jinho Seo, 2012, BMB reports.

Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling

C. Choi, E. Jho, Jaewhan Song, 2018, Oncogene.

Camptothecin and topotecan inhibit adipocyte differentiation by inducing degradation of PPARγ.

Sangsik Lee, Jaewhan Song, M. Jeong, 2015, Biochemical and biophysical research communications.

Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

R. Morimoto, S. Kornbluth, Jaewhan Song, 2001, The EMBO journal.

Bag1–Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth

R. Morimoto, Jaewhan Song, M. Takeda, 2001, Nature Cell Biology.

Regulator of Hsp70 Chaperone Activity Bag1 Functions in Vivo as a Negative

H. Kampinga, R. Morimoto, E. Nollen, 1999 .

Dual loss of USP10 and p14ARF protein expression is associated with poor prognosis in patients with small intestinal adenocarcinoma

Seung‐Mo Hong, C. Choi, J. Yi, 2018, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

D. Lane, Jaewang Ghim, M. Lee, 2009, The EMBO journal.

West Nile virus capsid protein induces p53‐mediated apoptosis via the sequestration of HDM2 to the nucleolus

Han-Woong Lee, S. Pyo, Jaewhan Song, 2007, Cellular microbiology.

STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy

Ji‐Young Shin, Hwajung Yi, Jaewhan Song, 2012, Clinical & Experimental Metastasis.

Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer

I. Choi, Seok-Jun Kim, Jaewhan Song, 2015, Clinical & Experimental Metastasis.

Targeting epithelial-mesenchymal transition pathway in hepatocellular carcinoma

Jaewhan Song, 2020, Clinical and molecular hepatology.

Multifaceted C-terminus of HSP70-interacting protein regulates tumorigenesis via protein quality control

Jaewhan Song, Jinho Seo, D. Seong, 2019, Archives of Pharmacal Research.

Multifaceted C-terminus of HSP70-interacting protein regulates tumorigenesis via protein quality control

Jaewhan Song, Jinho Seo, D. Seong, 2019, Archives of Pharmacal Research.

MafK positively regulates NF-κB activity by enhancing CBP-mediated p65 acetylation

Kyung-A Hwang, Jaewhan Song, Eun-Woo Lee, 2013, Scientific Reports.

Overall survival of pancreatic ductal adenocarcinoma is doubled by Aldh7a1 deletion in the KPC mouse

H. Jang, S. Woo, H. Kim, 2021, Theranostics.

Migrating Cells Dispose of Damaged Mitochondria into the Surrounding Environment

Jaewhan Song, Choong-Sil Lee, 2021, Molecules and cells.

Jab1 Induces the Cytoplasmic Localization and Degradation of p53 in Coordination with Hdm2*

Han-Woong Lee, Eun-Woo Lee, Han-Woong Lee, 2006, Journal of Biological Chemistry.

Extratelomeric functions of telomerase.

Han-Woong Lee, H. Chung, C. Cheong, 2005, Current molecular medicine.

The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in metabolism, immunity, and cancer

K. Park, Jaewhan Song, Jung-Hoon Kim, 2015, Archives of pharmacal research.

E3 LigaseCapsid Protein by Functioning as an MKRN1 Induces Degradation of West Nile

Jaewhan Song, J. Moon, W. Oh, 2012 .

MKRN1 Induces Degradation of West Nile Virus Capsid Protein by Functioning as an E3 Ligase

Jaewhan Song, Eun-Woo Lee, J. Moon, 2009, Journal of Virology.

The Cellular Inhibitor of the PKR Protein Kinase, P58IPK, Is an Influenza Virus-activated Co-chaperone That Modulates Heat Shock Protein 70 Activity*

M. Katze, Seng-Lai Tan, R. Morimoto, 1999, The Journal of Biological Chemistry.

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

D. Hwang, S. Koo, J. Seong, 2018, Nature Communications.

Mitochondrial dysfunction induced by callyspongiolide promotes autophagy-dependent cell death

Jae-seok Roe, Soohyung Lee, Jaewhan Song, 2021, BMB reports.

DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis

Young-Guen Kwon, Young-Myeong Kim, Haiying Zhang, 2022, BMC biology.

Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-α-Induced Apoptosis via Different Routes.

S. Kang, D. Kang, Jaewhan Song, 2019, Cell reports.

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury

P. Vandenabeele, S. Fulda, J. Bräsen, 2017, Cell Death and Disease.

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice.

B. Cho, Han-Woong Lee, J. Choi, 2012, The international journal of biochemistry & cell biology.

Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC

D. Hong, J. Son, Jaewhan Song, 2016, Cell Death & Disease.

SWCNTs induced autophagic cell death in human bronchial epithelial cells.

Jae-Ho Kim, Jae-Hyeok Lee, M. Cho, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy

Ji‐Young Shin, Hwajung Yi, Jaewhan Song, 2012, Clinical & Experimental Metastasis.

Biocompatible and Biodegradable Neuromorphic Device Based on Hyaluronic Acid for Implantable Bioelectronics

Won Kyung Min, Y. Rim, Jaewhan Song, 2021, Advanced Functional Materials.

Generation of reversible Rb-knockdown mice

Han-Woong Lee, S. Park, C. Cheong, 2005, Mechanisms of Ageing and Development.

C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ

M. Lee, Soyeon Shin, Jaewhan Song, 2017, Scientific Reports.

Transglutaminase 2-Mediated p53 Depletion Promotes Angiogenesis by Increasing HIF-1α-p300 Binding in Renal Cell Carcinoma

Jaewhan Song, S. Oh, Seon-Hyeong Lee, 2020, International journal of molecular sciences.

Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer

I. Choi, Seok-Jun Kim, Jaewhan Song, 2015, Clinical & Experimental Metastasis.

IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death

Jaewhan Song, Young Woo Nam, Chi Hyun Hwang, 2023, Cell Death & Differentiation.

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

D. Hwang, S. Koo, J. Seong, 2018, Nature Communications.

New role of E3 ubiquitin ligase in the regulation of necroptosis

Jaewhan Song, Jinho Seo, Eun-Woo Lee, 2016, BMB reports.

Deubiquitylation and stabilization of Notch1 intracellular domain by ubiquitin-specific protease 8 enhance tumorigenesis in breast cancer

S. Hewitt, Jae-seok Roe, S. Do, 2019, Cell Death & Differentiation.

Glatiramer acetate attenuates the activation of CD4+ T cells by modulating STAT1 and −3 signaling in glia

E. Park, H. Kim, Jaewhan Song, 2017, Scientific Reports.

Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC

Jaewhan Song, Jinho Seo, Soo-Mi Lee, 2018, Scientific Reports.

Cytoplasmic pro-apoptotic function of the tumor suppressor p73 is mediated through a modified mode of recognition of the anti-apoptotic regulator Bcl-XL

Ji-Young Lee, S. Chi, M. Yoon, 2018, The Journal of Biological Chemistry.

Jab1 Mediates Cytoplasmic Localization and Degradation of West Nile Virus Capsid Protein*

Han-Woong Lee, S. Pyo, Jaewhan Song, 2006, Journal of Biological Chemistry.

Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation

Kyung-A Hwang, K. Park, Jaewhan Song, 2013, Cell Death and Differentiation.

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells.

Jae-Ho Kim, Younghun Kim, Sang-Wook Kim, 2014, Toxicology in vitro : an international journal published in association with BIBRA.

USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics

Jaewhan Song, Eun-Woo Lee, D. Seong, 2015, Cell Death and Differentiation.

Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF.

S. Hewitt, C. Choi, J. Fukuoka, 2017, Cancer research.

Camptothecin and topotecan inhibit adipocyte differentiation by inducing degradation of PPARγ.

Sangsik Lee, Jaewhan Song, M. Jeong, 2015, Biochemical and biophysical research communications.

Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice.

B. Cho, Han-Woong Lee, J. Choi, 2012, The international journal of biochemistry & cell biology.

Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation.

Jaewhan Song, W. Oh, 2003, Molecules and cells.