T. Nagai

发表

Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cells

I. Komuro, T. Minamino, Kaoru Ito, 2013, Hypertension Research.

Urotensin II inhibits the proliferation but not the differentiation of cardiac side population cells

I. Komuro, Y. Zou, M. Kanda, 2011, Peptides.

Promotion of cardiac regeneration by cardiac stem cells.

I. Komuro, I. Shiojima, T. Nagai, 2005, Circulation research.

[Regenerative medicine for heart diseases].

I. Komuro, T. Nagai, 2009, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine.

Angiotensin II Type 1a Receptor Is Involved in Cell Infiltration, Cytokine Production, and Neovascularization in Infarcted Myocardium

I. Komuro, T. Sugaya, T. Minamino, 2004, Arteriosclerosis, thrombosis, and vascular biology.

G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes

I. Komuro, T. Minamino, Y. Zou, 2005, Nature Medicine.

Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II

S. Kudoh, I. Komuro, A. Fukamizu, 2004, Nature Cell Biology.

Microtubule Stabilization in Pressure Overload Cardiac Hypertrophy

Hiroshi Sato, D. Menick, T. Nagai, 1997, Journal of Cell Biology.

Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes.

I. Komuro, H. Kasanuki, H. Akazawa, 2013, The Journal of Biological Chemistry.

Corrigendum: IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

I. Komuro, I. Shiojima, Yuzuru Ito, 2014, Nature.

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

I. Komuro, I. Shiojima, Yuzuru Ito, 2008, Nature.

Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction

A. Iwama, I. Komuro, H. Akazawa, 2016, PloS one.

Implication of cardiac remodeling in heart failure: mechanisms and therapeutic strategies.

I. Komuro, H. Hasegawa, T. Nagai, 2003, Internal medicine.

Csx/Nkx2-5 Is Required for Homeostasis and Survival of Cardiac Myocytes in the Adult Heart*

Y. Hiroi, I. Komuro, I. Shiojima, 2002, The Journal of Biological Chemistry.

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors prevent the development of cardiac hypertrophy and heart failure in rats.

I. Komuro, H. Hasegawa, M. Asakawa, 2003, Journal of molecular and cellular cardiology.

Naoto Cardiac Hypertrophy In Vitro and In Vivo Plays a Critical Role in Inhibition of γ Peroxisome Proliferator-Activated Receptor

H. Uozumi, I. Komuro, T. Kadowaki, 2002 .

A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5

S. Kudoh, I. Komuro, N. Mochizuki, 2004, The Journal of cell biology.

Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Inhibition of Cardiac Hypertrophy In Vitro and In Vivo

H. Uozumi, I. Komuro, T. Kadowaki, 2002 .

Prognostic evaluation of congestive heart failure in patients with Duchenne muscular dystrophy--retrospective study using non-invasive cardiac function tests.

T. Nagai, 1989, Japanese circulation journal.

Diphtheria Toxin-induced Autophagic Cardiomyocyte Death Plays a Pathogenic Role in Mouse Model of Heart Failure*

I. Komuro, Y. Zou, H. Akazawa, 2004, Journal of Biological Chemistry.

Reactive oxygen species are critical in the oleic acid-mediated mitogenic signaling pathway in vascular smooth muscle cells.

B. Egan, T. Nagai, G. Lu, 1998, Hypertension.

Pathway in Vascular Smooth Muscle Cells Mediated Mitogenic Signaling − Reactive Oxygen Species Are Critical in the Oleic Acid

B. Egan, T. Nagai, G. Lu, 1998 .

Beating is necessary for transdifferentiation of skeletal muscle‐derived cells into cardiomyocytes

I. Komuro, H. Akazawa, H. Wada, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

REACTIVE OXYGEN SPECIES INDUCE CARDIOMYOCYTE APOPTOSIS PARTLY THROUGH TNF-α

S. Kudoh, Y. Yazaki, I. Komuro, 2002 .

Lipopolysaccharide-Induced Tumor Necrosis Factor-Activated Receptor Activators Inhibit − Peroxisome Proliferator

M. Asakawa, T. Oka, T. Nagai, 2000 .

Peroxisome Proliferator–Activated Receptor Activators Inhibit Lipopolysaccharide-Induced Tumor Necrosis Factor-α Expression in Neonatal Rat Cardiac Myocytes

I. Komuro, M. Asakawa, T. Oka, 2000 .

A Crucial Role of Activin A-Mediated Growth Hormone Suppression in Mouse and Human Heart Failure

N. Hagiwara, I. Komuro, T. Okano, 2011, PloS one.

SSBP1: A Target Molecule for Prevention of Fibrosis

M. Kanda, T. Nagai, 2018 .

Leukemia Inhibitory Factor Enhances Survival of Cardiomyocytes and Induces Regeneration of Myocardium After Myocardial Infarction

I. Komuro, T. Minamino, Y. Zou, 2003, Circulation.

Adult Cardiac Sca-1-positive Cells Differentiate into Beating Cardiomyocytes*

I. Komuro, H. Kasanuki, H. Akazawa, 2004, Journal of Biological Chemistry.

Anti-In fl ammatory Peptides From Cardiac Progenitors Ameliorate Dysfunction After Myocardial Infarction

I. Komuro, Yoshio Kobayashi, M. Kanda, 2014 .

Anti‐Inflammatory Peptides From Cardiac Progenitors Ameliorate Dysfunction After Myocardial Infarction

I. Komuro, Yoshio Kobayashi, M. Kanda, 2014, Journal of the American Heart Association.

G-CSF Prevents Cardiac Remodeling after Myocardial Infarction by Activating Jak/STAT in Cardiomyocytes(Vascular Regeneration (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

I. Komuro, T. Minamino, M. Harada, 2005 .

Heat Shock Transcription Factor 1 Protects Cardiomyocytes From Ischemia/Reperfusion Injury

I. Komuro, T. Minamino, Y. Zou, 2003, Circulation.

Cardiac sarcoidosis evaluated by multimodality imaging.

I. Komuro, S. Nomura, N. Funabashi, 2011, International journal of cardiology.

5-HT2A receptors stimulate mitogen-activated protein kinase via H2O2 generation in rat renal mesangial cells

J. Raymond, G. Collinsworth, J. S. Grewal, 2000 .

5-HT(2A) receptors stimulate mitogen-activated protein kinase via H(2)O(2) generation in rat renal mesangial cells.

J. Raymond, G. Collinsworth, J. S. Grewal, 2000, American journal of physiology. Renal physiology.

The Clinical Effect of Aprindine on Ventricular Extrasystole

Masato Nakamura, M. Inagaki, T. Nagai, 1992 .

Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo.

H. Uozumi, I. Komuro, T. Kadowaki, 2002, Circulation.

Cardiac side population cells and Sca-1-positive cells.

I. Komuro, T. Nagai, K. Matsuura, 2013, Methods in molecular biology.

Macrophage Inflammatory Protein-1α Relates to the Recruitment of Inflammatory Cells in Myosin-Induced Autoimmune Myocarditis in Rats

K. Hiroshima, H. Ohwada, M. Hiroe, 2001, Laboratory Investigation.

Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes.

I. Komuro, T. Saito, M. Asakawa, 2000, Circulation research.

Neonatal Rat Heart Response to Pressure Overload.

M. Kanda, T. Nagai, 2017, International heart journal.

The cell cycle can be a new target for the treatment of cardiac hypertrophy?

H. Takano, T. Nagai, I. Komuro, 2001, Journal of molecular and cellular cardiology.

5-Hydroxytryptamine1A receptor/Gibetagamma stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of src in chinese hamster ovary fibroblasts.

J. Raymond, G. Collinsworth, J. S. Grewal, 2000, The Biochemical journal.

Peripheral-blood or bone-marrow mononuclear cells for therapeutic angiogenesis?

T. Minamino, H. Toko, K. Tateno, 2002, The Lancet.

Detection of Takayasu arteritis in early stage by computed tomography.

I. Komuro, Katsuya Yoshida, N. Funabashi, 2002, International Journal of Cardiology.

AFLUID April 47/4

J. Raymond, G. Collinsworth, J. S. Grewal, 2000 .

Cardiac sarcoidosis complicated with atrioventricular block and wall thinning, edema and fibrosis in left ventricle: confirmed recovery to normal sinus rhythm and visualization of edema improvement by administration of predonisolone.

I. Komuro, N. Funabashi, M. Uehara, 2011, International journal of cardiology.

Systemic Transfusion of Human Umbilical Cord-Derived Mesenchymal Stromal Cells　- Toward Less Invasive and More Effective Cell Therapy for Severe Peripheral Arterial Disease.

T. Nagai, 2022, Circulation journal : official journal of the Japanese Circulation Society.

Angiosarcoma in the right atria demonstrated by fusion images of multislice computed tomography and positron emission tomography using F-18 Fluoro-Deoxyglucose.

M. Miyazaki, I. Komuro, N. Funabashi, 2007, International journal of cardiology.

Changes in the peptidergic innervation in the carotid body of rats chronically exposed to hypercapnic hypoxia: an effect of arterial CO2 tension.

T. Kawakami, T. Takenaka, T. Nagai, 2002, Histology and histopathology.

Reactive oxygen species in mechanical stress-induced cardiac hypertrophy.

Y. Zou, R. Nagai, I. Komuro, 2001, Biochemical and biophysical research communications.

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

I. Komuro, I. Shiojima, S. Nomura, 2012, Cell.

Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice.

Teruo Okano, Hiroshi Kasanuki, Tatsuya Shimizu, 2009, The Journal of clinical investigation.

Promotion of CHIP-Mediated p53 Degradation Protects the Heart From Ischemic Injury

I. Komuro, I. Shiojima, S. Nomura, 2010, Circulation research.

Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling

T. Noda, I. Komuro, I. Shiojima, 2015, Nature Communications.

Inhibitory molecules in signal transduction pathways of cardiac hypertrophy.

I. Komuro, Y. Zou, H. Akazawa, 2002, Hypertension research : official journal of the Japanese Society of Hypertension.

Integrins Play a Critical Role in Mechanical Stress–Induced p38 MAPK Activation

S. Kudoh, I. Komuro, Y. Zou, 2002, Hypertension.

Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo

I. Komuro, A. Uezumi, H. Akazawa, 2007, The Journal of cell biology.

Gene and cytokine therapy for heart failure: molecular mechanisms in the improvement of cardiac function.

I. Komuro, T. Nagai, 2012, American journal of physiology. Heart and circulatory physiology.

Phosphatidylinositol 3-Kinase–Akt Pathway Plays a Critical Role in Early Cardiomyogenesis by Regulating Canonical Wnt Signaling

Hiroyuki Aburatani, Hiroyuki Takano, Hiroshi Akazawa, 2005, Circulation research.

Angiotensin II Induces Premature Senescence of Vascular Smooth Muscle Cells and Accelerates the Development of Atherosclerosis via a p21-Dependent Pathway

I. Komuro, S. Kaneko, T. Minamino, 2006, Circulation.

Cardiac Hypertrophic and Developmental Regulation of the β-Tubulin Multigene Family*

D. Menick, K. Blade, G. Cooper, 1999, The Journal of Biological Chemistry.

Integrin-Dependent and -Independent Signaling During Pressure-Overload Cardiac Hypertrophy

M. Zile, C. Baicu, C. Willey, 2000 .

Critical Roles of Muscle-Secreted Angiogenic Factors in Therapeutic Neovascularization

I. Komuro, F. Nomura, T. Minamino, 2006, Circulation research.

Angiotensin II Induces Premature Senescence of Vascular Smooth Muscle Cells and Accelerates the Development of Atherosclerosis via a p 21-Dependent Pathway

I. Komuro, S. Kaneko, T. Minamino, 2006 .

Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases.

I. Komuro, Y. Zou, H. Akazawa, 2003, Antioxidants & redox signaling.

Sodium calcium exchanger plays a key role in alteration of cardiac function in response to pressure overload

A. Yao, M. Shimoyama, I. Komuro, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle

I. Komuro, H. Kasanuki, T. Minamino, 2004, The Journal of cell biology.

Regeneration of the Cardiac Conduction System by Adipose Tissue-Derived Stem Cells.

I. Komuro, Yoshio Kobayashi, M. Kanda, 2015, Circulation journal : official journal of the Japanese Circulation Society.

Effects of antiarrhythmic drugs on the hyperpolarization-activated cyclic nucleotide-gated channel current.

M. Miyazaki, I. Komuro, T. Kishimoto, 2009, Journal of pharmacological sciences.

Stretch-modulation of second messengers: effects on cardiomyocyte ion transport.

S. Kudoh, I. Komuro, Y. Zou, 2003, Progress in biophysics and molecular biology.

Molecular and cellular mechanisms of mechanical stress-induced cardiac hypertrophy.

I. Komuro, Y. Zou, H. Akazawa, 2002, Endocrine journal.

DDAVP Does not Induce the Release of Thrombomodulin from Endothelial Cells

T. Nagai, H. Niwano, Hoyu Takahashi, 1991, Thrombosis and Haemostasis.

Direct measurement of Ca2+ concentration in the SR of living cardiac myocytes.

A. Miyawaki, A. Yao, O. Kohmoto, 2004, Biochemical and biophysical research communications.

Steroid-responsive thromboangiitis obliterans

I. Komuro, T. Minamino, A. Naito, 2004, The Lancet.

Clinical Benefit of a Therapy with OPC-13340, a Calcium Antagonist, on Exercise Hemodynamics in Effort Angina

T. Nagai, Toshihiro Saito, Y. Inagaki, 1991 .

Ca2+—Dependent Signaling Pathways Through Calcineurin and Ca2+ Calmodulin—Dependent Protein Kinase in Development of Cardiac Hypertrophy

I. Komuro, Y. Zou, H. Akazawa, 2003 .

Pleiotropic effects of cytokines on acute myocardial infarction: G-CSF as a novel therapy for acute myocardial infarction.

I. Komuro, H. Akazawa, M. Harada, 2003, Current pharmaceutical design.

Implantation of cardiac progenitor cells using self-assembling peptide improves cardiac function after myocardial infarction.

I. Komuro, M. Kanda, A. Naito, 2010, Journal of molecular and cellular cardiology.

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

I. Komuro, I. Shiojima, T. Minamino, 2012, Cell.

Mitochondrial Aldehyde Dehydrogenase 2 Plays Protective Roles in Heart Failure After Myocardial Infarction via Suppression of the Cytosolic JNK/p53 Pathway in Mice

P. Ping, I. Komuro, T. Kawamoto, 2014, Journal of the American Heart Association.

Pericardial Grafting of Cardiac Progenitor Cells in Self-Assembling Peptide Scaffold Improves Cardiac Function After Myocardial Infarction

H. Akazawa, M. Kanda, T. Nagai, 2023, Cell transplantation.

Cdc42 plays a critical role in assembly of sarcomere units in series of cardiac myocytes.

Y. Yazaki, I. Komuro, R. Nagai, 2003, Biochemical and biophysical research communications.

Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice.

N. Hagiwara, I. Komuro, T. Okano, 2009, Journal of Clinical Investigation.

Gene and cytokine therapy for heart failure: molecular mechanisms in the improvement of cardiac function.

I. Komuro, T. Nagai, 2012, American journal of physiology. Heart and circulatory physiology.

Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo

I. Komuro, A. Uezumi, H. Akazawa, 2007, The Journal of cell biology.

Microtubule Stabilization in Pressure Overload Cardiac Hypertrophy

Hiroshi Sato, D. Menick, T. Nagai, 1997, The Journal of cell biology.

The role of PPARgamma-dependent pathway in the development of cardiac hypertrophy.

I. Komuro, H. Hasegawa, T. Nagai, 2003, Timely topics in medicine. Cardiovascular diseases.