Kwangwook Ahn

发表

Piperidine acetic acid based γ-secretase modulators directly bind to Presenilin-1.

K. Bales, Douglas S. Johnson, Yue-Ming Li, 2011, ACS chemical neuroscience.

Activation and intrinsic γ-secretase activity of presenilin 1

Xulun Zhang, S. Sisodia, Yue-Ming Li, 2010, Proceedings of the National Academy of Sciences.

Structure of γ-Secretase and Its Trimeric Pre-activation Intermediate by Single-particle Electron Microscopy*

W. Rice, I. Ubarretxena-Belandia, F. Renzi, 2011, The Journal of Biological Chemistry.

Imaging and Functional Analysis of γ-Secretase and Substrate in a Proteolipobead System with an Activity-Based Probe.

Yue-Ming Li, Kwangwook Ahn, M. Gilchrist, 2016, Analytical chemistry.

Soluble oligomers of the intramembrane serine protease YqgP are catalytically active in the absence of detergents.

I. Ubarretxena-Belandia, Yue-Ming Li, Kwangwook Ahn, 2008, Biochemistry.

Anti-neuroinflammatory activity of 1,5-benzodiazepine derivatives.

Eunjung Moon, S. Kim, Sung-Hoon Kim, 2010, Bioorganic & medicinal chemistry letters.

Pentacycle derivatives as cannabinoid CB1 receptor ligands.

Min Ju Kim, Jinhwa Lee, Kwangwook Ahn, 2009, Bioorganic & medicinal chemistry letters.

A substituted 3,4-dihydropyrimidinone derivative (compound D22) prevents inflammation mediated neurotoxicity; role in microglial activation in BV-2 cells.

Eunjung Moon, S. Kim, Kwangwook Ahn, 2012, Bioorganic & medicinal chemistry letters.

Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists.

Jong Yup Kim, Jinhwa Lee, Kwangwook Ahn, 2009, Bioorganic & medicinal chemistry letters.

γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin*

K. Bales, Christopher W. am Ende, Martin Pettersson, 2013, The Journal of Biological Chemistry.

Increased Expression of PS1 Is Sufficient to Elevate the Level and Activity of γ-Secretase In Vivo

D. Price, P. Wong, S. Sisodia, 2011, PloS one.

Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand.

Min Ju Kim, Jinhwa Lee, Kwangwook Ahn, 2010, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.

Jong Yup Kim, Jinhwa Lee, Kwangwook Ahn, 2008, Bioorganic & medicinal chemistry.

Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonists.

Jinhwa Lee, Kwangwook Ahn, H. Seo, 2008, Bioorganic & medicinal chemistry letters.

Modulation of γ-Secretase Reduces β-Amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease

Xulun Zhang, Rudolph E. Tanzi, Sangram S. Sisodia, 2010, Neuron.

Identification of a tetratricopeptide repeat-like domain in the nicastrin subunit of γ-secretase using synthetic antibodies

A. Koide, S. Koide, G. Dolios, 2012, Proceedings of the National Academy of Sciences of the United States of America.

ChemInform Abstract: anti-Neuroinflammatory Activity of 1,5-Benzodiazepine Derivatives.

Eunjung Moon, S. Kim, Sung-Hoon Kim, 2010 .