C. Stiff

发表

Piperidine acetic acid based γ-secretase modulators directly bind to Presenilin-1.

K. Bales, Douglas S. Johnson, Yue-Ming Li, 2011, ACS chemical neuroscience.

Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH).

B. Cravatt, J. Dunbar, Yun-Song Song, 2009, Bioorganic & medicinal chemistry letters.

O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors.

B. Cravatt, M. Niphakis, Douglas S. Johnson, 2012, ACS chemical neuroscience.

Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors.

D. Romero, M. Zhong, M. T. Sweeney, 2007, Bioorganic & medicinal chemistry letters.

Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles.

D. Rohrer, K. Marotti, A. Thorarensen, 2007, Bioorganic & medicinal chemistry letters.

A simple determination of alkylsilane monolayer population density

G. Fryxell, J. Linehan, C. Stiff, 2006 .

Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy.

Gregory W. Kauffman, David S. Ramirez, L. Pustilnik, 2017, MedChemComm.

Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability.

Gregory W. Kauffman, L. Pustilnik, A. Stepan, 2015, ACS medicinal chemistry letters.

Protocol for the Direct Conversion of Lactones to Lactams Mediated by 1,5,7-Triazabicyclo[4.4.0]dec-5-ene: Synthesis of Pyridopyrazine-1,6-diones.

Christopher W. am Ende, Danica A Rankic, C. Stiff, 2017, The Journal of organic chemistry.

Mechanistic and pharmacological characterization of PF-04457845 : a highly potent and selective FAAH inhibitor that reduces inflammatory and noninflammatory pain

Shobha N. Bhattachar, D. Nomura, B. Cravatt, 2011 .

Studies on the Bisoxazoline and (-)-Sparteine Mediated Enantioselective Addition of Organolithium Reagents to Imines.

S. Denmark, N. Nakajima, O. J. Nicaise, 2008, Advanced synthesis & catalysis.

Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin.

Gregory W. Kauffman, L. Pustilnik, A. Stepan, 2015, Bioorganic & medicinal chemistry letters.

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

Benjamin F. Cravatt, Paul Wren, Shobha N. Bhattachar, 2011, Journal of Pharmacology and Experimental Therapeutics.

Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.

Raymond C Stevens, Marya Liimatta, R. Stevens, 2009, Chemistry & biology.

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.

Shobha N. Bhattachar, B. Cravatt, D. T. Dudley, 2011, ACS medicinal chemistry letters.

Bacterial translation inhibitors, 1-acylindazol-3-ols as anthranilic acid mimics.

D. Rohrer, K. Marotti, A. Thorarensen, 2008, Bioorganic & medicinal chemistry letters.

Novel γ-secretase modulators: a review of patents from 2008 to 2010

Gregory W. Kauffman, Martin Pettersson, Christopher W. am Ende, 2011, Expert opinion on therapeutic patents.

Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.

Malcolm C. Mackenny, P. Fish, T. Ryckmans, 2008, Bioorganic & medicinal chemistry letters.

Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators.

Gregory W. Kauffman, L. Pustilnik, S. Sakya, 2014, Journal of medicinal chemistry.

Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators.

Gregory W. Kauffman, L. Pustilnik, S. Sakya, 2012, Bioorganic & medicinal chemistry letters.

Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.

R. Stevens, J. Long, B. Cravatt, 2009, Chemistry & biology.

Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.

Malcolm C. Mackenny, P. Fish, T. Ryckmans, 2008, Bioorganic & medicinal chemistry letters.