L. Morford

发表

Preclinical safety evaluations supporting pediatric drug development with biopharmaceuticals: strategy, challenges, current practices.

C. Bowman, D. Blanset, W. Halpern, 2011, Birth defects research. Part B, Developmental and reproductive toxicology.

Rethinking developmental toxicity testing: Evolution or revolution?

A. Piersma, T. Knudsen, A. Hoberman, 2018, Birth defects research.

α‐Phenyl‐N‐tert‐butyl nitrone attenuates methamphetamine‐induced depletion of striatal dopamine without altering hyperthermia

C. Vorhees, G. Cappon, L. Morford, 1996, Synapse.

Applying a weight of evidence approach to the evaluation of developmental toxicity of biopharmaceuticals.

C. Bowman, D. Blanset, W. Halpern, 2018, Regulatory toxicology and pharmacology : RTP.

12.19 – Developmental Neurotoxicology

J. Henck, L. Morford, 2010 .

Juvenile Toxicity Testing to Support Clinical Trials in the Pediatric Population

M. Beck, A. Faqi, L. Morford, 2012 .

LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.

Matthew M. Abernathy, R. Gimeno, F. Willard, 2022, Cell metabolism.

Hazard identification and predictability of children's health risk from animal data.

W. Breslin, J. DeSesso, J. Henck, 2004, Environmental health perspectives.

The benefits, limitations and opportunities of preclinical models for neonatal drug development

G. Schmitt, S. Seo, A. Inselman, 2022, Disease models & mechanisms.

Prenatal phenytoin exposure and spatial navigation in offspring: effects on reference and working memory and on discrimination learning.

C. Vorhees, L. Morford, M. A. Schilling, 1999, Neurotoxicology and teratology.

Toxicology and Nonclinical Safety Assessment in Pharmaceutical Discovery and Development

Matthew M. Abernathy, V. Reynolds, J. Bhalli, 2021 .

Science‐Based Approach to Harmonize Contraception Recommendations in Clinical Trials and Pharmaceutical Labels

K. Turner, C. Bowman, K. Thompson, 2022, Clinical pharmacology and therapeutics.

Periadolescent rats (P41-50) exhibit increased susceptibility to D-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21-30 or P31-40) or adult rats (P51-60).

Sandra L. Wood, C. Vorhees, A. Mccrea, 2005, Neurotoxicology and teratology.

Interactions of dopamine D1 and D2 receptor antagonists with D‐methamphetamine‐induced hyperthermia and striatal dopamine and serotonin reductions

C. Vorhees, L. Morford, H. Broening, 2005, Synapse.

Ontogeny of methamphetamine-induced neurotoxicity and associated hyperthermic response.

C. Vorhees, G. Cappon, L. Morford, 1997, Brain research. Developmental brain research.

Evaluation of neonatal exposure to cocaine on learning, activity, startle, scent marking, immobility, and plasma cocaine concentrations.

C. Vorhees, G. Cappon, L. Morford, 2000, Neurotoxicology and teratology.

Effects of prenatal cocaine on Morris and Barnes maze tests of spatial learning and memory in the offspring of C57BL/6J mice.

C. Vorhees, L. Morford, M. T. Williams, 2000, Neurotoxicology and teratology.

3,4-Methylenedioxymethamphetamine (Ecstasy)-Induced Learning and Memory Impairments Depend on the Age of Exposure during Early Development

Charles V. Vorhees, C. Vorhees, L. Morford, 2001, The Journal of Neuroscience.

Administration of D,L-fenfluramine to rats produces learning deficits in the Cincinnati water maze but not the Morris water maze: relationship to adrenal cortical output.

Sandra L. Wood, C. Vorhees, A. Mccrea, 2002, Neurotoxicology and teratology.

Developmental D‐methamphetamine treatment selectively induces spatial navigation impairments in reference memory in the Morris water maze while sparing working memory

Sandra L. Wood, C. Vorhees, T. Wallace, 2003, Synapse.

Elevations in plasmatic titers of corticosterone and aldosterone, in the absence of changes in ACTH, testosterone, or glial fibrillary acidic protein, 72 h following D,L-fenfluramine or D-fenfluramine administration to rats.

C. Vorhees, A. Mccrea, L. Morford, 2001, Neurotoxicology and teratology.

Preweaning treatment with methamphetamine induces increases in both corticosterone and ACTH in rats.

C. Vorhees, A. Mccrea, L. Morford, 2000, Neurotoxicology and teratology.

Developmental 3,4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection stress

Sandra L. Wood, C. Vorhees, A. Mccrea, 2003, Brain Research.

Adult Learning Deficits after Neonatal Exposure tod-Methamphetamine: Selective Effects on Spatial Navigation and Memory

C. Vorhees, L. Morford, M. S. Moran, 2000, The Journal of Neuroscience.

Enhancement of cocaine-induced hyperthermia fails to elicit neurotoxicity.

C. Vorhees, G. Cappon, L. Morford, 1998, Neurotoxicology and teratology.

Impaired spatial and sequential learning in rats treated neonatally with d‐fenfluramine

C. Vorhees, L. Morford, G. Gudelsky, 2002, The European journal of neuroscience.

Genetic differences in spatial learning between Dark Agouti and Sprague-Dawley strains: possible correlation with the CYP2D2 polymorphism in rats treated neonatally with methamphetamine.

C. Vorhees, G. Cappon, L. Morford, 1999, Pharmacogenetics.

Current Topics in Postnatal Behavioral Testing

C. Vorhees, J. Henck, L. Morford, 2016, International journal of toxicology.

Juvenile Bone Toxicity: Study Considerations, Regulations, and Techniques for Assessment

M. McVean, K. Funk, L. Morford, 2022, International journal of toxicology.

PDGFRα monoclonal antibody: Assessment of toxicity in juvenile mice administered a murine surrogate antibody of olaratumab

M. Bhaskaran, L. Morford, D. Luffer-Atlas, 2023, Birth defects research.

Assessing Risks in Children | Mini-monograph Critical Periods and Important Milestones in Development Hazard Identification and Predictability of Children's Health Risk from Animal Data

W. Breslin, J. DeSesso, J. Henck, 2022 .