J. Roodt

发表

Tirofiban versus abciximab: tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates

W. V. Rensburg, J. Roodt, S. Lamprecht, 2012, Clinical and Experimental Medicine.

Rational humanization of the powerful antithrombotic anti-GPIbα antibody: 6B4

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2006, Thrombosis and Haemostasis.

Inhibition of von Willebrand factor-platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons.

H. Deckmyn, K. Vanhoorelbeke, J. Roodt, 2012, Blood.

Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs.

P. Stanssens, M. Lauwereys, K. Silence, 2011, Blood.

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus).

H. Deckmyn, K. Vanhoorelbeke, J. Roodt, 2010, Blood.

Antithrombotic effect of platelet glycoprotein Ib-blocking monoclonal antibody Fab fragments in nonhuman primates.

H. Deckmyn, J. Roodt, S. Lamprecht, 2000, Arteriosclerosis, thrombosis, and vascular biology.

N-acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura.

H. Deckmyn, José A López, C. Tersteeg, 2017, Blood.

Correlation of in vitro platelet quality measurements with in vivo platelet viability in human subjects

J. Roodt, R. Goodrich, Junzhi Li, 2006, Vox sanguinis.

The humanized anti-glycoprotein Ib monoclonal antibody h6B4-Fab is a potent and safe antithrombotic in a high shear arterial thrombosis model in baboons

H. Deckmyn, J. Roodt, S. Lamprecht, 2008, Thrombosis and Haemostasis.

Coronary artery in-stent stenosis persists despite inhibition of the von Willebrand factor - collagen interaction in baboons

S. Janssens, H. Deckmyn, S. D. De Meyer, 2007, Thrombosis and Haemostasis.

The Effect of Monoclonal Anti-human-platelet Antibodies on Platelet Kinetics in a Baboon Model: IgG Subclass Dependency

J. Roodt, P. Badenhorst, L. Coetzee, 2000, Thrombosis and Haemostasis.

PLATSAK, a potent antithrombotic and fibrinolytic protein, inhibits arterial and venous thrombosis in a baboon model.

J. Roodt, S. Lamprecht, H. Kotze, 2000, Thrombosis research.

Antithrombotic Activity of Bay u3405, a Thromboxane A2-Antagonist, in Patients with Dacron Aortic Grafts: a Random Controlled Clinical Trial

R. Schall, M. G. Lötter, J. Roodt, 1993, Thrombosis and Haemostasis.

A human monoclonal antibody inhibiting partially factor VIII activity reduces thrombus growth in baboons

P. Verhamme, J. Saint-Remy, M. Jacquemin, 2009, Journal of thrombosis and haemostasis : JTH.

Determination of the dosage of recombinant hirudin to inhibit arterial thrombosis in baboons.

J. Roodt, S. Lamprecht, P. Badenhorst, 2000, Journal of pharmaceutical sciences.

Influence of platelet membrane sialic acid and platelet-associated IgG on ageing and sequestration of blood platelets in baboons.

M. G. Lötter, J. Roodt, P. Badenhorst, 1993, Thrombosis and haemostasis.

Concurrent label method with 111In and 51Cr allows accurate evaluation of platelet viability of stored platelet concentrates

J. Roodt, A. Heaton, S. Holme, 1993, British journal of haematology.

Guidance for diagnosis and treatment of disseminated intravascular coagulation from harmonization of the recommendations from three guidelines

V. Laux, H. Redl, S. Bahrami, 2017 .

Influence of Platelet Membrane Sialic Acid and Platelet-Associated IgG on Ageing and Sequestration of Blood Platelets in Baboons

J. Roodt, P. Badenhorst, V. Wyk, 1993, Thrombosis and Haemostasis.

Evaluation of (o)-[77Br]bromohippuran as renal tubular function agent.

C. Herbst, A. van Aswegen, A. Otto, 1985, The International journal of applied radiation and isotopes.

Radionuclide cholescintigraphic imaging: an evaluation of several 99mTc labelled hepatobiliary radiopharmaceuticals.

A. van Aswegen, A. Otto, J. Van Wyk, 1986, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

In Vivo Inhibition of Acute Platelet-Dependent Thrombosis in a Baboon Model by BAY U3405, a Thromboxane A2-Receptor Antagonist

J. Roodt, S. Lamprecht, P. Badenhorst, 1993, Thrombosis and Haemostasis.

The influence of platelet-graft interaction on platelet survival in patients with aortobifemoral Dacron grafts.

C. Herbst, J. Roodt, P. Badenhorst, 1992, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

Comparison of oxine and tropolone methods for labeling human platelets with indium-111.

J. Roodt, P. Badenhorst, H. Kotze, 1991, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura.

J. Holz, F. Callewaert, H. Ulrichts, 2012, Blood.

Dual inhibition of thrombin and activated factor X attenuates disseminated intravascular coagulation and protects organ function in a baboon model of severe Gram-negative sepsis

M. van Griensven, V. Laux, H. Redl, 2017, Critical Care.

Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4.

J. Desmet, H. Deckmyn, K. Vanhoorelbeke, 2006, Thrombosis and haemostasis.

Blood platelet kinetics in normal subjects modelled by compartmental analysis

J. Roodt, P. Badenhorst, M. Sweetlove, 2004, European Journal of Nuclear Medicine.

The Cape Chacma baboon is not suitable for evaluating human targeted anti-GPVI agents

J. Roodt, P. Badenhorst, W. J. Janse van Rensburg, 2015, Platelets.

baboon model of acquired thrombotic thrombocytopenic purpura Short title: ALX-0681 treatment of acquired TTP in baboons Authors

J. Holz, F. Callewaert, H. Ulrichts, 2017 .

ALX-0081 Nanobody™, an Engineered Bivalent Anti-Thrombotic Drug Candidate with Improved Efficacy and Safety as Compared to the Marketed Drugs.

K. Silence, P. Casteels, H. Jonckheere, 2006 .

baboon model of acquired thrombotic thrombocytopenic purpura Short title: ALX-0681 treatment of acquired TTP in baboons Authors

J. Holz, F. Callewaert, H. Ulrichts, 2017 .