G. Christie

发表

A Human Homolog of Angiotensin-converting Enzyme

Nigel M. Hooper, Eric Karran, Anthony J. Turner, 2000, The Journal of Biological Chemistry.

Identification of a novel aspartic protease (Asp 2) as beta-secretase.

C. Southan, F. Walsh, T. Smith, 1999, Molecular and cellular neurosciences.

Structure-activity relationship of hydroxamate-based inhibitors on the secretases that cleave the amyloid precursor protein, angiotensin converting enzyme, CD23, and pro-tumor necrosis factor-alpha.

N. Hooper, R. Mayer, A. Faller, 2002, Biochemistry.

Structure−Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor-α†

N. Hooper, R. Mayer, A. Faller, 2002 .

Presenilins--in search of functionality.

D. Allsop, E. Karran, J. Davis, 1998, Biochemical Society transactions.

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

David G. Tew, C. Southan, F. Walsh, 1999, Molecular and Cellular Neuroscience.

Prodomain Processing of Asp1 (BACE2) Is Autocatalytic*

C. Dingwall, S. Moore, I. Hussain, 2001, The Journal of Biological Chemistry.

Drug-protein conjugates--XVII. The effect of storage on the antigenicity and immunogenicity of benzylpenicillin in the rat.

B. K. Park, G. Christie, J. Coleman, 1988, Biochemical pharmacology.

Drug-protein conjugates--XII. A study of the disposition, irreversible binding and immunogenicity of penicillin in the rat.

N. Kitteringham, B. K. Park, G. Christie, 1987, Biochemical pharmacology.

ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.

C. Southan, P. Murdock, F. Walsh, 2000, Molecular and cellular neurosciences.

Endocytosis and recycling of the complex between CD23 and HLA‐DR in human B cells

P. Murdock, B. Sutton, S. Karagiannis, 2001, Immunology.

CD23 (FcepsilonRII) release from cell membranes is mediated by a membrane-bound metalloprotease.

D. Earnshaw, R. Mayer, G. Christie, 1998, The Biochemical journal.

Potential roles of metalloprotease mediated ectodomain cleavage in signaling by the endothelial receptor tyrosine kinase Tie-1.

M. McCarthy, N. Brindle, G. Christie, 1999, Laboratory investigation; a journal of technical methods and pathology.

In vitro cytocidal effects on Trypanosoma brucei and inhibition of Leishmania major GP63 by peptidomimetic metalloprotease inhibitors.

N. Hooper, G. Christie, J. Bangs, 2001, Molecular and biochemical parasitology.

A survey of the prevalence of penicillin-specific IgG, IgM and IgE antibodies detected by ELISA and defined by hapten inhibition, in patients with suspected penicillin allergy and in healthy volunteers.

A. Breckenridge, B. K. Park, G. Christie, 1988, British journal of clinical pharmacology.

Drug-protein conjugates--XVIII. Detection of antibodies towards the antimalarial amodiaquine and its quinone imine metabolite in man and the rat.

A. Breckenridge, B. K. Park, G. Christie, 1989, Biochemical pharmacology.

Neurobiology: Inhibitor of neurite outgrowth in humans

R. Prinjha, F. Walsh, S. Moore, 2000, Nature.

ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site

C. Southan, P. Murdock, F. Walsh, 2000, Molecular and Cellular Neuroscience.

Drug-protein conjugates--XIII. The disposition of the benzylpenicilloyl hapten conjugated to albumin.

N. Kitteringham, B. K. Park, G. Christie, 1987, Biochemical pharmacology.

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

D. Owen, E. Karran, J. Hawkins, 2000, The Biochemical journal.

Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

D. Riddell, C. Dingwall, I. Hussain, 2001, Current Biology.

Design of Antisense (Complementary) Peptides as Selective Inhibitors of Cytokine Interleukin-1†

Andrew D. Miller, J. Raynes, G. Christie, 1997 .

IgE secretion is attenuated by an inhibitor of proteolytic processing of CD23 (FcεRII)

P. Murdock, R. Mayer, B. Bolognese, 1997 .

IgE secretion is attenuated by an inhibitor of proteolytic processing of CD23 (Fc epsilonRII).

P. Murdock, R. Mayer, L. Marshall, 1997, European journal of immunology.

In search of an enzyme: the β-secretase of Alzheimer's disease is an aspartic proteinase

C. Dingwall, D. Simmons, D. Howlett, 2000, Trends in Neurosciences.

Characterization of peptidyl boronic acid inhibitors of mammalian 20 S and 26 S proteasomes and their inhibition of proteasomes in cultured cells.

M. Mclaughlin, D. Allsop, S. Assinder, 2000, The Biochemical journal.

Inhibition of β‐Amyloid Aggregation and Neurotoxicity by Complementary (Antisense) Peptides

Andrew D. Miller, G. Christie, J. Heal, 2002, Chembiochem : a European journal of chemical biology.

A search within the IL-1 type I receptor reveals a peptide with hydropathic complementarity to the IL-1beta trigger loop which binds to IL-1 and inhibits in vitro responses.

A. Miller, J. Raynes, K. Ray, 1999, Molecular immunology.

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

D. Owen, E. Karran, J. Hawkins, 2000, The Biochemical journal.

Identification of a soluble, high affinity human interleukin 4 binding protein in normal human urine.

G. Christie, B. Weston, I. Dacey, 1995, Cytokine.

Fibrillogenesis of beta-amyloid.

D. Allsop, E. Karran, D. Howlett, 1998, Biochemical Society transactions.

Biological activity associated with a high molecular weight form of β-amyloid.

D. Allsop, E. Karran, K. H. Jennings, 1999 .