Song Gao

发表

Hepatoenteric recycling is a new disposition mechanism for orally administered phenolic drugs and phytochemicals in rats

V. Tam, R. Singh, Yifan Tu, 2021, eLife.

A New Strategy to Rapidly Evaluate Kinetics of Glucuronide Efflux by Breast Cancer Resistance Protein (BCRP/ABCG2)

Taijun Yin, Song Gao, M. Hu, 2012, Pharmaceutical Research.

Significantly Decreased and More Variable Expression of Major CYPs and UGTs in Liver Microsomes Prepared from HBV-Positive Human Hepatocellular Carcinoma and Matched Pericarcinomatous Tissues Determined Using an Isotope Label-free UPLC-MS/MS Method

Jian Shi, Song Gao, M. Hu, 2014, Pharmaceutical Research.

Impact of diet on irinotecan toxicity in mice.

M. Ittmann, R. Ghose, Song Gao, 2018, Chemico-biological interactions.

Absolute quantification of UGT1A1 in various tissues and cell lines using isotope label-free UPLC-MS/MS method determines its turnover number and correlates with its glucuronidation activities.

Taijun Yin, Song Gao, M. Hu, 2014, Journal of pharmaceutical and biomedical analysis.

Role of Bacterial Translocation in the Progressive and Delayed Irinotecan Induced Diarrhea.

M. Overman, R. Ghose, Song Gao, 2018 .

Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity

B. Moorthy, R. Ghose, Song Gao, 2020, Expert opinion on drug metabolism & toxicology.

Optimal Piperacillin-Tazobactam Dosing Strategies against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae

V. Tam, R. Cantón, Song Gao, 2018, Antimicrobial Agents and Chemotherapy.

Response to Letter to the Editor on “Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein”

Taijun Yin, Song Gao, M. Hu, 2012, Drug Metabolism and Disposition.

Determination of pharmacokinetics of chrysin and its conjugates in wild-type FVB and Bcrp1 knockout mice using a validated LC-MS/MS method.

Taijun Yin, Song Gao, M. Hu, 2015, Journal of agricultural and food chemistry.

Enhancement of Oral Bioavailability of 20(S)-Ginsenoside Rh2 through Improved Understanding of Its Absorption and Efflux Mechanisms

Taijun Yin, Song Gao, M. Hu, 2011, Drug Metabolism and Disposition.

Validated LC-MS/MS method for the determination of 3-hydroxflavone and its glucuronide in blood and bioequivalent buffers: application to pharmacokinetic, absorption, and metabolism studies.

Taijun Yin, Song Gao, M. Hu, 2013, Journal of pharmaceutical and biomedical analysis.

Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoids.

Song Gao, M. Hu, Baojian Wu, 2013, Molecular pharmaceutics.

Age-and Region-Dependent Disposition of Raloxifene in Rats

Dong Liang, Song Gao, M. Hu, 2021, Pharmaceutical Research.

Development and validation of ultra-high-performance liquid chromatography–mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats

Li Li, Song Gao, Ting Du, 2021 .

Development and validation of ultra-high-performance liquid chromatography-MS method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats.

Li Li, Dong Liang, Taijun Yin, 2020, Journal of separation science.

Development and validation of an LC-MS/MS method for the quantification of flavonoid glucuronides (wogonoside, baicalin, and apigenin-glucuronide) in the bile and blood samples: application to a portal vein infusion study.

Lei Zhou, Li Li, Yifan Tu, 2020, Analytical biochemistry.

Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice.

R. Singh, Song Gao, M. Hu, 2010, Journal of pharmaceutical and biomedical analysis.

Bioavailability challenges associated with development of anti-cancer phenolics.

Song Gao, M. Hu, Ming Hu, 2010, Mini reviews in medicinal chemistry.

A validated liquid chromatography-tandem mass spectrometry method for the determination of methyl gallate and pentagalloyl glucopyranose: application to pharmacokinetic studies.

P. Pithayanukul, Song Gao, M. Hu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats.

Dong Liang, Song Gao, M. Hu, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development and validation of a highly sensitive UPLC-MS/MS method for simultaneous determination of aconitine, mesaconitine, hypaconitine, and five of their metabolites in rat blood and its application to a pharmacokinetics study of aconitine, mesaconitine, and hypaconitine

W. Liu, Song Gao, M. Hu, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

Validated LC-MS/MS method for the determination of maackiain and its sulfate and glucuronide in blood: application to pharmacokinetic and disposition studies.

Taijun Yin, Song Gao, M. Hu, 2011, Journal of pharmaceutical and biomedical analysis.

Amino acid facilitates absorption of copper in the Caco-2 cell culture model.

Taijun Yin, Song Gao, M. Hu, 2014, Life sciences.

Determining &bgr;-lactam exposure threshold to suppress resistance development in Gram-negative bacteria

A. Oliver, V. Tam, R. Cantón, 2017, The Journal of antimicrobial chemotherapy.

Disposition of flavonoids via recycling: Direct biliary excretion of enterically or extrahepatically derived flavonoid glucuronides.

S. Basu, Taijun Yin, Song Gao, 2016, Molecular nutrition & food research.

In vitro glucuronidation of methyl gallate and pentagalloyl glucopyranose by liver microsomes.

P. Pithayanukul, Song Gao, M. Hu, 2016, Drug metabolism and pharmacokinetics.

Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt.

Li Li, Lijun Zhu, R. Ghose, 2020, Toxicology and applied pharmacology.

The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.

Wei Liu, Taijun Yin, Song Gao, 2013, Toxicology letters.

Metabolic profiles of Xiao Chai Hu Tang in mouse plasma, bile and urine by the UHPLC-ESI-Q-TOF/MS technique.

J. Chen, Shiming Du, Song Gao, 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Glucuronides Hydrolysis by Intestinal Microbial β-Glucuronidases (GUS) Is Affected by Sampling, Enzyme Preparation, Buffer pH, and Species

Dong Liang, Song Gao, M. Hu, 2021, Pharmaceutics.

Acute changes in colonic PGE2 levels as a biomarker of efficacy after treatment of the Pirc (F344/NTac-Apc am1137) rat with celecoxib

Li Li, Taijun Yin, Song Gao, 2019, Inflammation Research.

Accurate quantification of PGE2 in the polyposis in rat colon (Pirc) model by surrogate analyte‐based UPLC–MS/MS

L. Kwong, R. Dashwood, R. Singh, 2018, Journal of pharmaceutical and biomedical analysis.

Simultaneous determinations of 17 marker compounds in Xiao-Chai-Hu-Tang by LC-MS/MS: Application to its pharmacokinetic studies in mice.

Li Li, Song Gao, M. Hu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The role of gut microbial β-glucuronidase in drug disposition and development.

Clement T Y Chan, T. Savidge, R. Singh, 2022, Drug discovery today.

Xiao-Chai-Hu-Tang (XCHT) Intervening Irinotecan's Disposition: The Potential of XCHT in Alleviating Irinotecan-Induced Diarrhea.

S. Basu, Li Li, R. Ghose, 2019, Current cancer drug targets.

Bioactivity and Bioavailability of Ginsenosides are Dependent on the Glycosidase Activities of the A/J Mouse Intestinal Microbiome Defined by Pyrosequencing

R. Gibbs, J. Petrosino, Zhi-Hong Jiang, 2012, Pharmaceutical Research.

Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis

L. Hedstrom, V. Jala, B. Haribabu, 2013, Antimicrobial Agents and Chemotherapy.

Metabolite Identification of a Novel Anti-Leishmanial Agent OJT007 in Rat Liver Microsomes Using LC-MS/MS

Song Gao, Ting Du, Manvir Kaur, 2022, Molecules.

27-Hydroxyoleanolic Acid Type Triterpenoid Saponins from Anemone raddeana rhizome

Jincai Lu, Song Gao, Li-hua Fan, 2010, Natural product communications.

A novel strategy for screening bioavailable quality markers of traditional Chinese medicine by integrating intestinal absorption and network pharmacology: Application to Wu Ji Bai Feng Pill.

D. Yuan, Li Li, Taijun Yin, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies.

Taijun Yin, Song Gao, Rongjin Sun, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Oral Bioavailability Challenges of Natural Products Used in Cancer Chemoprevention

S. Basu, A. Deb, Song Gao, 2013 .

Pharmacokinetic and Metabolic Profiling of Key Active Components of Dietary Supplement Magnolia officinalis Extract for Prevention against Oral Carcinoma.

Li Li, R. Singh, Taijun Yin, 2020, Journal of agricultural and food chemistry.

Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP

Taijun Yin, Song Gao, Shufan Ge, 2015, Pharmaceutical Research.

Sensitive and robust UPLC-MS/MS method to determine the gender-dependent pharmacokinetics in rats of emodin and its glucuronide.

Wei Liu, Song Gao, Zhongqiu Liu, 2011, Journal of pharmaceutical and biomedical analysis.

Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B).

Taijun Yin, Song Gao, M. You, 2015, Journal of ethnopharmacology.

Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method.

Taijun Yin, Song Gao, M. You, 2010, Journal of pharmaceutical and biomedical analysis.

Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre‐exposure prophylaxis

R. L. Hood, A. Ballerini, A. Grattoni, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Glucuronidation: driving factors and their impact on glucuronide disposition

S. Basu, Jian Shi, R. Singh, 2017, Drug metabolism reviews.

Bioavailability challenges associated with development of saponins as therapeutic and chemopreventive agents.

S. Basu, A. Deb, Song Gao, 2012, Current drug targets.

Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides.

Taijun Yin, Song Gao, Yingjie Wei, 2017, Molecular pharmaceutics.

Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis

M. You, E. Szabo, R. Lubet, 2013, Molecular carcinogenesis.

Development and validation of a rapid and sensitive UPLC-MS/MS assay for simultaneous quantification of paclitaxel and cyclopamine in mouse whole blood and tissue samples.

Chun Li, C. Hsiao, Song Gao, 2019, Biomedical chromatography : BMC.

Racial Disparity in Drug Disposition in the Digestive Tract

Dong Liang, Song Gao, Edward C. Bell, 2021, International journal of molecular sciences.

Pharmacokinetics and Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Neutropenic Murine Pneumonia Model

V. Tam, Song Gao, Jian Zhou, 2017, Antimicrobial Agents and Chemotherapy.

Characterization of the Major Components in Different Green Tea Dietary Supplements using HPLC and Multivariate Statistical Analysis

W. Jian, Song Gao, Guangyi Yang, 2015 .

Comparative Pharmacokinetic Profiling of Different Polymyxin B Components

V. Tam, Song Gao, Pooja Manchandani, 2016, Antimicrobial Agents and Chemotherapy.

Development and validation of an UPLC-MS/MS method for the quantification of irinotecan, SN-38 and SN-38 glucuronide in plasma, urine, feces, liver and kidney: Application to a pharmacokinetic study of irinotecan in rats.

S. Basu, Taijun Yin, Song Gao, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Inhibition of P-Glycoprotein Leads to Improved Oral Bioavailability of Compound K, an Anticancer Metabolite of Red Ginseng Extract Produced by Gut Microflora

Jing-Rong Wang, Taijun Yin, Song Gao, 2012, Drug Metabolism and Disposition.

Comparison of Absolute Expression and Turnover Number of COX-1 and COX-2 in Human and Rodent Cells and Tissues

Zuoxu Xie, H. Himburg, Li Li, 2022, Journal of inflammation research.

A validated ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of polymyxin B in mouse serum and epithelial lining fluid: application to pharmacokinetic studies.

V. Tam, Song Gao, D. Chow, 2013, The Journal of antimicrobial chemotherapy.

Breast Cancer Resistance Protein (ABCG2) Determines Distribution of Genistein Phase II Metabolites: Reevaluation of the Roles of ABCG2 in the Disposition of Genistein

Taijun Yin, Song Gao, Wen Jiang, 2012, Drug Metabolism and Disposition.

Developing nutritional component chrysin as a therapeutic agent: Bioavailability and pharmacokinetics consideration, and ADME mechanisms

Dong Liang, Song Gao, Ting Du, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Development and validation of a sensitive LC–MS/MS method for simultaneous determination of eight tyrosine kinase inhibitors and its application in mice pharmacokinetic studies

Yifan Tu, Taijun Yin, Song Gao, 2018, Journal of pharmaceutical and biomedical analysis.

Design and Synthesis of a Novel NIR Celecoxib-Based Fluorescent Probe for Cyclooxygenase-2 Targeted Bioimaging in Tumor Cells

Zuoxu Xie, Li Li, Taijun Yin, 2020, Molecules.

Highly variable contents of phenolics in St. John's Wort products affect their transport in the human intestinal Caco-2 cell model: pharmaceutical and biopharmaceutical rationale for product standardization.

Taijun Yin, Song Gao, Wen Jiang, 2010, Journal of agricultural and food chemistry.

An UPLC-MS/MS method for quantifying tetrandrine and its metabolite berbamine in human blood: Application to a human pharmacokinetic study.

Meiling Zhu, Song Gao, Chenning Zhang, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bioactivity and Bioavailability of Ginsenosides are Dependent on the Glycosidase Activities of the A/J Mouse Intestinal Microbiome Defined by Pyrosequencing

R. Gibbs, J. Petrosino, Taijun Yin, 2013, Pharmaceutical Research.

Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles.

Song Gao, Yong Ma, Ming Hu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Establishment and use of new MDCK II cells overexpressing both UGT1A1 and MRP2 to characterize flavonoid metabolism via the glucuronidation pathway.

Taijun Yin, Song Gao, Guangyi Yang, 2016, Molecular Nutrition & Food Research.

A New Strategy to Rapidly Evaluate Kinetics of Glucuronide Efflux by Breast Cancer Resistance Protein (BCRP/ABCG2)

Taijun Yin, Song Gao, Baojian Wu, 2012, Pharmaceutical Research.

Acute changes in colonic PGE2 levels as a biomarker of efficacy after treatment of the Pirc (F344/NTac-Apc am1137) rat with celecoxib

Li Li, Taijun Yin, Song Gao, 2019, Inflammation Research.

Jian Shi, Song Gao, Ying Wang, 2015, Pharmaceutical Research.

Metabolism of Phenolic Compounds in LPS-stimulated Raw264.7 Cells Can Impact Their Anti-inflammatory efficacy: Indication of Hesperetin.

Taijun Yin, Song Gao, Haoqing Chen, 2018, Journal of agricultural and food chemistry.

Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies

P. Dash, Jing Zhao, Taijun Yin, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP

Taijun Yin, Song Gao, Shufan Ge, 2016, Pharmaceutical Research.

S. Basu, Taijun Yin, Song Gao, 2016, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Enhancement of oral bioavailability of ginsenoside 20(s)-Rh2 through improved understanding of its absorption and efflux mechanisms

Taijun Yin, Song Gao, Zhen Yang, 2011 .

Optimized rat models better mimic patients with irinotecan-induced severe diarrhea

Li Li, R. Singh, Taijun Yin, 2024, Toxicology mechanisms and methods.

Determination of pharmacokinetics of chrysin and its conjugates in wild-type FVB and Bcrp1 knockout mice using a validated LC-MS/MS method.

Taijun Yin, Song Gao, Shufan Ge, 2015, Journal of agricultural and food chemistry.