B. Henkle

发表

Select animal models of colitis and their value in predicting clinical efficacy of biological therapies in ulcerative colitis

J. Bilsborough, Marie F. Fiorino, B. Henkle, 2020, Expert opinion on drug discovery.

Predictability of Peripheral Lymphocyte Reduction of Novel S1P1 Agonists by In Vitro GPCR Signaling Profile

R. Bürli, E. Tominey, B. Henkle, 2013, Journal of biomolecular screening.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase.

T. Harvey, R. Syed, C. Dominguez, 2005, Bioorganic & medicinal chemistry letters.

Articular Mesenchymal Stem Cell ( MSC ) and Effects of Growth Differentiation Factor-5 ( GDF-5 )

S. Davis, B. Henkle, J. Whoriskey, 2011 .

Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitors.

Matthew R. Lee, A. Tasker, Bin Wu, 2010, Journal of medicinal chemistry.

Identification of triazolopyridazinones as potent p38α inhibitors.

S. Chmait, B. Herberich, Matthew R. Lee, 2012, Bioorganic & medicinal chemistry letters.

Part 2: Structure-activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.

S. Chmait, K. Miner, Matthew R. Lee, 2010, Bioorganic & medicinal chemistry letters.

Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass*

Thomas M. Dillon, Alain Balland, Gregory C. Flynn, 2008, Journal of Biological Chemistry.

Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase.

Christopher Mohr, Lisa Sherman, S. Chmait, 2010, Journal of medicinal chemistry.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

Xin Huang, David Powers, Daniela Metz, 2006, Journal of medicinal chemistry.

Adenoviral gene transfer is inhibited by soluble factors in malignant pleural effusions.

R. Batra, S. Dubinett, B. Henkle, 2000, American journal of respiratory cell and molecular biology.

Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold.

R. Syed, B. Herberich, Matthew R. Lee, 2008, Journal of medicinal chemistry.

3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase.

R. Syed, Matthew R. Lee, A. Tasker, 2008, Journal of medicinal chemistry.

Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.

S. Chmait, K. Miner, Matthew R. Lee, 2009, Bioorganic & medicinal chemistry letters.

Structural and Functional Characterization of Disulfide Isoforms of the Human IgG 2 Subclass *

Douglas S Rehder, T. Dillon, P. Bondarenko, 2008 .

Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase.

S. Chmait, B. Herberich, Matthew R. Lee, 2010, Journal of medicinal chemistry.