P. Conlon

发表

Human endometriosis is associated with plasma cells and overexpression of B lymphocyte stimulator

Jose Rojas, Albert Zlotnik, R. Maki, 2007, Proceedings of the National Academy of Sciences.

Effect of IL-7 on the growth of fetal thymocytes in culture.

J. Watson, P. Morrissey, P. Conlon, 1989, Journal of immunology.

Murine thymocytes proliferate in direct response to interleukin-7.

S. Reed, R. Nordan, P. Morrissey, 1989, Blood.

Molecular Determinants of Melanocortin 4 Receptor Ligand Binding and MC4/MC3 Receptor Selectivity

R. Maki, S. Nickolls, Xiaochuan Wang, 2003, Journal of Pharmacology and Experimental Therapeutics.

Short peptide-based tolerogens without self-antigenic or pathogenic activity reverse autoimmune disease.

D. Mitchell, L. Steinman, N. Grabie, 1998, Journal of immunology.

Functional domains of recombinant bactericidal/permeability increasing protein (rBPI23).

D. Burke, P. Conlon, D. Kelner, 1994, The Journal of biological chemistry.

Antigen Specific Immunotherapy of Multiple Sclerosis

L. Steinman, P. Conlon, 2001, Journal of Clinical Immunology.

NBI‐5788, an altered MBP83‐99 peptide, induces a T‐helper 2–like immune response in multiple sclerosis patients

J. Antel, P. Crowe, P. Conlon, 2000, Annals of neurology.

Microbial Epitopes Act as Altered Peptide Ligands to Prevent Experimental Autoimmune Encephalomyelitis

A. Sette, H. Garren, L. Steinman, 1999, The Journal of experimental medicine.

Autoimmune Disease Self-Antigenic or Pathogenic Activity Reverse Short Peptide-Based Tolerogens Without

D. Mitchell, L. Steinman, N. Grabie, 1998 .

Viral damage and the breakdown of self-tolerance

L. Steinman, P. Conlon, 1997, Nature Medicine.

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

U. Utz, A. Waisman, D. Mitchell, 1996, Nature.

Differential signaling and hierarchical response thresholds induced by an immunodominant peptide of myelin basic protein and an altered peptide ligand in human T cells.

A. Gaur, J. Sidney, A. Sette, 1998, Human immunology.

Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factor.

V. Price, K. Grabstein, P. Conlon, 1986, Science.

Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma

S. Reed, C. Nathan, K. Grabstein, 1987, The Journal of experimental medicine.

Interleukin-4 (B-cell stimulatory factor-1) augments the in vivo generation of cytotoxic cells in immunosuppressed animals.

P. Morrissey, K. Grabstein, P. Conlon, 1989, Biotechnology therapeutics.

Interleukin 1 regulates hematopoietic activity, a role previously ascribed to hemopoietin 1.

A. Larsen, P. Conlon, R. Tushinski, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Body Weight Regulation by Selective MC4 Receptor Agonists and Antagonists

N. Ling, Beth A. Fleck, M. Joppa, 2003, Annals of the New York Academy of Sciences.

Affinity Crosslinking and SDS-PAGE

T. Hopp, P. Conlon, S. Gillis, 2003 .

Detection and characterization of high affinity plasma membrane receptors for human interleukin 1

C. March, T. Hopp, S. Dower, 1985, The Journal of experimental medicine.

bactericidal / permeability-increasing protein fragment of lipid A required for binding of a recombinant Characterization of the structural elements in

D. Lill-Elghanian, C. Tsai, H. Kasler, 1994 .

Fas-Mediated Cell Death of Brain Microglia The Chemokine Fractalkine Inhibits

K. Bacon, P. Conlon, S. Boehme, 2000 .

The Chemokine Fractalkine Inhibits Fas-Mediated Cell Death of Brain Microglia

K. Bacon, P. Conlon, S. Boehme, 2000, Journal of Immunology.

Cytokine-dependent thymocyte responses: characterization of IL 1 and IL 2 target subpopulations and mechanism of action.

C. Henney, P. Conlon, S. Gillis, 1982, Journal of immunology.

Prolonged expression of lipopolysaccharide (LPS)-induced inflammatory genes in whole blood requires continual exposure to LPS

P. Conlon, R. Dedrick, Russell L. Dedrick, 1995, Infection and immunity.

Regulation of murine macrophage proinflammatory and anti‐inflammatory cytokines by ligands for peroxisome proliferator‐activated receptor‐γ: counter‐regulatory activity by IFN‐γ

P. Crowe, Eric B. Johnson, P. Conlon, 2002, Journal of Leukocyte Biology.

Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines

C. March, T. Hopp, K. Grabstein, 1986, The Journal of experimental medicine.

Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines

C. March, T. Hopp, K. Grabstein, 1986, The Journal of experimental medicine.

Granulocyte-macrophage colony-stimulating factor

S. Reed, P. Morrissey, K. Grabstein, 1989 .

Granulocyte/macrophage colony stimulating factor. A potent activation signal for mature macrophages and monocytes.

S. Reed, P. Morrissey, K. Grabstein, 1989, International archives of allergy and applied immunology.

PRECURSOR FREQUENCY AND LYTIC SPECIFICITY OF INTERLEUKIN 2 AND INTERLEUKIN 4‐RESPONSIVE MURINE LYMPHOCYTES

K. Grabstein, P. Conlon, M. Widmer, 1990, Transplantation.

Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms

L. Steinman, P. Crowe, P. Conlon, 1997, Journal of Neuroimmunology.

Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87–99)

U. Utz, L. Steinman, Roland Martin, 1996, European journal of immunology.

Molecular Characterization of Interleukin 2

J. Watson, M. B. Frank, C. Henney, 1982, Federation proceedings.

Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration.

K. Bacon, P. Crowe, S. K. Sullivan, 1999, Journal of immunology.

Immunological characterization and therapeutic activity of an altered-peptide ligand, NBI-6024, based on the immunodominant type 1 diabetes autoantigen insulin B-chain (9-23) peptide.

D. Wegmann, P. Gottlieb, A. Putnam, 2002, Diabetes.

Administration of IL-7 to normal mice stimulates B-lymphopoiesis and peripheral lymphadenopathy.

P. Morrissey, K. Charrier, P. Conlon, 1991, Journal of immunology.

The effects of interleukin-2 (IL-2) on primary in vivo immune responses

P. Conlon, S. Hefeneider, S. Gillis, 1982 .

Stress and autoimmunity: the neuropeptides corticotropin-releasing factor and urocortin suppress encephalomyelitis via effects on both the hypothalamic-pituitary-adrenal axis and the immune system.

N. Ling, L. Steinman, W. Vale, 1997, Journal of immunology.

Administration of IL-7 to mice with cyclophosphamide-induced lymphopenia accelerates lymphocyte repopulation.

D. Williams, P. Morrissey, P. Conlon, 1991, Journal of immunology.

Anatomy of mitochondrial DNA from Paramecium aurelia

R. Maki, P. Conlon, J. Laping, 2004, Molecular and General Genetics MGG.

Human T-cell response to myelin basic protein peptide (83-99): Extensive heterogeneity in antigen recognition, function, and phenotype

B. Hemmer, H. McFarland, R. Martin, 1997, Neurology.

Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen.

B. Gallis, P. Conlon, D. Mochizuki, 1986, The Journal of biological chemistry.

Human thymocytes express CCR-3 and are activated by eotaxin.

N. Taylor, T. Schall, K. Franz-Bacon, 1999, Blood.

Immunomodulation in Type 1 Diabetes by NBI‐6024, an Altered Peptide Ligand of the Insulin B(9−23) Epitope

R. Maki, P. Gottlieb, A. Putnam, 2006, Scandinavian journal of immunology.

Localization of human mononuclear cell interleukin 1.

T. Hopp, K. Prickett, K. Grabstein, 1987, Journal of immunology.

SJL and NOD macrophages are uniquely characterized by genetically programmed, elevated expression of the IL‐12(p40) gene, suggesting a conserved pathway for the induction of organ‐specific autoimmunity

Eric B. Johnson, P. Conlon, D. Beller, 2001, Journal of leukocyte biology.

Control of experimental contact sensitivity.

S. Miller, S. Miller, P. Conlon, 1980, Advances in immunology.

Efficient induction of immediate tolerance to contact sensitivity by hapten-modified spleen cells requires Ia+ cells compatible with recipient

P. Conlon, H. Claman, J. Moorhead, 1979, Nature.

The induction of tolerance to DNFB contact sensitivity using hapten modified lymphoid cells. I. Cellular requirements for rapid induction of tolerance.

P. Conlon, H. Claman, J. Moorhead, 1980, Cellular immunology.

Molecular Modification of Lymphokines by in Vitro Mutagenesis

D. Cosman, S. Dower, A. Larsen, 1987, Annals of the New York Academy of Sciences.

Persistence of immune responses to altered and native myelin antigens in patients with multiple sclerosis treated with altered peptide ligand.

A. Bar-Or, J. Antel, P. Duquette, 2002, Clinical immunology.

Production of IL-1α and IL-1β by clones of EBV transformed, human B cells

A. Larsen, P. Conlon, S. Gillis, 1987 .

The induction of tolerance to DNFB contact sensitivity by using hapten-modified lymphoid cells. III. Effects of hapten concentration on the ability of MLS-disparate cells to induce rapid unresponsiveness.

S. Miller, P. Conlon, H. Claman, 1980, Journal of immunology.

The intricate interplay among body weight, stress, and the immune response to friend or foe.

L. Steinman, R. Maki, P. Conlon, 2003, The Journal of clinical investigation.

Altered Peptide Ligands and MS Treatment

L. Steinman, P. Conlon, 2002, Science.

Immunosuppressive phenotype of corticotropin-releasing factor transgenic mice is reversed by adrenalectomy.

N. Ling, A. Gaur, E. D. De Souza, 1997, Cellular immunology.

Human interleukin 1. Purification to homogeneity

C. March, T. Hopp, S. Erb, 1985, The Journal of experimental medicine.

In vivo interleukin 2 administration augments the generation of alloreactive cytolytic T lymphocytes and resident natural killer cells.

C. Henney, P. Conlon, S. Hefeneider, 1983, Journal of immunology.

Phosphorylation of the CD8 antigen on cytotoxic human T cells in response to phorbol myristate acetate or antigen-presenting B cells.

B. Gallis, P. Conlon, D. Mochizuki, 1987, Journal of immunology.

Serological visualization of interleukin 2.

P. Conlon, S. Hefeneider, S. Gillis, 1983, Science.

Generation of anti-peptide monoclonal antibodies which recognize mature CSF-2 alpha (IL 3) protein.

C. March, T. Hopp, L. Park, 1985, Journal of immunology.

Regulation of murine macrophage proinflammatory and anti-inflammatory cytokines by ligands for peroxisome proliferator-activated receptor-gamma: counter-regulatory activity by IFN-gamma.

P. Crowe, Eric B. Johnson, P. Conlon, 2002, Journal of leukocyte biology.

Lymphokine purification by reversed-phase high-performance liquid chromatography.

M. L. Remerowski, C. March, P. Conlon, 1984, Journal of chromatography.

Reactivity of monoclonal antibody E5 with endotoxin. II. Binding to short- and long-chain smooth lipopolysaccharides.

P. Conlon, H. Gazzano-Santoro, J. B. Parent, 1992, Circulatory shock.

Limiting dilution analysis of interleukin 2 and colony-stimulating factor producer cells in normal and autoimmune mice.

C. Henney, S. Dower, P. Conlon, 1984, Journal of immunology.

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

C. March, T. Hopp, D. Cerretti, 1985, Nature.

Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.

L. Steinman, Roland Martin, J. Oksenberg, 2002, Annual review of neuroscience.

Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

R. Black, C. March, T. Hopp, 1988, The Journal of biological chemistry.

Evaluation of experimentally induced Fusobacterium necrophorum infections in mice

P. Conlon, K. Hepper, G. W. Teresa, 1977, Infection and immunity.

The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.

K. Prickett, D. Cosman, S. Dower, 1987, The Journal of biological chemistry.

A rapid biologic assay for the detection of interleukin 1.

P. Conlon, 1983, Journal of immunology.

A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification

Kathryn S. Prickett, Carl J. March, C. March, 1988, Bio/Technology.

IL-1 as adjuvant. Role of T cells in the augmentation of specific antibody production by recombinant human IL-1 alpha.

S. Reed, K. Grabstein, P. Conlon, 1989, Journal of immunology.

Purification to homogeneity of a human hematopoietic growth factor that stimulates the growth of a murine interleukin 3-dependent cell line.

J. Watson, C. March, P. Crosier, 1986, Journal of immunology.

Interleukine-1 purifiée

C. March, T. Hopp, D. Cerretti, 1985 .

Characterization of γ-Aminobutyric Acid Receptor GABAB(1e), a GABAB(1) Splice Variant Encoding a Truncated Receptor*

R. Maki, G. Barry, P. Conlon, 2000, The Journal of Biological Chemistry.

Effect of infection with murine recombinant retroviruses containing the v-src oncogene on interleukin 2- and interleukin 3-dependent growth states.

J. Watson, P. Conlon, S. Gillis, 1987, Journal of immunology.

Biochemical comparison of murine colony-stimulating factors secreted by a T cell lymphoma and a myelomonocytic leukemia.

J. Watson, P. Conlon, S. Gillis, 1984, Journal of immunology.

Identification of differentially expressed genes induced by transient ischemic stroke.

R. Maki, G. Barry, A. Foster, 2002, Brain research. Molecular brain research.

High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide

P. Elsbach, J. Weiss, P. Conlon, 1992, Infection and immunity.

Regulation of antibody production in vitro by granulocyte-macrophage colony stimulating factor.

V. Price, D. Cosman, K. Grabstein, 1986, The Journal of molecular and cellular immunology : JMCI.

Nature of hapten-modified determinants involved in induction of T cell tolerance and suppressor T cells to NDFB contact sensitivity.

H. Grey, S. Colon, M. Sy, 1980, Journal of immunology.

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial

A. Evans, M. Filippi, C. Pozzilli, 2000, Nature Medicine.

The Immunobiology of Multiple Sclerosis: An Autoimmune Disease of the Central Nervous System

L. Steinman, J. Oksenberg, Jingwu Z. Zhang, 1999, Neurobiology of Disease.

Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology.

R. Houghten, C. Pinilla, B. Hemmer, 1998, Journal of immunology.

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin.

A. Gaur, W. Kwok, P. Gottlieb, 2001, The Journal of clinical investigation.

Development and characterization of antiserum to murine granulocyte-macrophage colony-stimulating factor.

L. Park, P. Conlon, D. Urdal, 1986, Journal of immunology.

IL 1 expression in a clone of human T cells.

A. Larsen, P. Conlon, R. Acres, 1987, Journal of immunology.

The treatment of induced immune deficiency with interleukin-2.

C. Henney, P. Conlon, S. Gillis, 1985, Immunology letters.

Contribution of Individual Amino Acids Within MHC Molecule or Antigenic Peptide to TCR Ligand Potency1

Clemencia Pinilla, Bernhard Hemmer, Henry F. McFarland, 2000, The Journal of Immunology.

Cytokine-dependent thymocyte responses. II. Generation of cytotoxic T lymphocytes from immature thymocytes.

C. Henney, P. Conlon, S. Gillis, 1982, Journal of immunology.

Lymphopoiesis and IL-7.

J. Watson, P. Morrissey, R. Goodwin, 1990, International journal of cell cloning.

Reactivity of monoclonal antibody E5 with endotoxin. I. Binding to lipid A and rough lipopolysaccharides.

P. Conlon, H. Gazzano-Santoro, J. B. Parent, 1992, Circulatory shock.

Induction of tolerance to 1-fluoro-2,4-dinitrobenzene contact sensitivity with hapten-modified lymphoid cells. II. Selective tolerance in F1 mice of T cell subsets recognizing 1-fluoro-2,4- dinitrobenzene associated with parental major histocompatibility complex antigens

S. Miller, P. Conlon, H. Claman, 1980, The Journal of experimental medicine.

Rational design, synthesis, and structure-activity relationships of aryltriazoles as novel corticotropin-releasing factor-1 receptor antagonists.

D. Grigoriadis, Chen Chen, P. Crowe, 2005, Journal of medicinal chemistry.

Molecular characterization of interleukin 2.

J. Watson, M. B. Frank, C. Henney, 1982, Immunological reviews.

Modifications of peptide ligands enhancing T cell responsiveness imply large numbers of stimulatory ligands for autoreactive T cells.

J. Coligan, B. Hemmer, H. McFarland, 1997, Journal of immunology.

In vivo treatment with IL-1 reduces the severity and duration of antigen-induced arthritis in rats.

G. Callis, C. Jacobs, P. Conlon, 1988, Journal of immunology.

A RECOMBINANT AMINO‐TERMINAL FRAGMENT OF BACTERICIDAL/PERMEABILITY INCREASING PROTEIN (rBPI23) INHIBITS SOLUBLE CD14‐MEDIATED LIPOPLYSACCHARIDE‐INDUCED ENDOTHELIAL ADHERENCE FOR HUMAN NEUTROPHILS

P. Conlon, Kun Huang, Dianne M. Fishwild, 1994, Shock.

A recombinant amino terminal fragment of bactericidal/permeability‐increasing protein inhibits the induction of leukocyte responses by LPS

P. Elsbach, J. Weiss, P. Conlon, 1993, Journal of leukocyte biology.

Lymphokines: from conjecture to the clinic.

T. Hopp, V. Price, D. Cosman, 1986, Seminars in oncology.

Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells

S. Reed, R. Nordan, P. Morrissey, 1989, The Journal of experimental medicine.

The Interleukin- 1 Receptor Binds the Human Interleukin- la! Precursor but Not the Interleukin- 1@ Precursor*

Gillis, S. Dower, Steven, 2001 .

Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23

D. Lill-Elghanian, H. Kasler, P. Conlon, 1995, Infection and immunity.