I. Alfonso

发表

Untargeted assignment and automatic integration of 1H NMR metabolomic datasets using a multivariate curve resolution approach.

R. Tauler, Francesc Puig-Castellví, I. Alfonso, 2017, Analytica chimica acta.

Unraveling the Multistimuli Responses of a Complex Dynamic System of Pseudopeptidic Macrocycles.

R. Tauler, Francesc Puig-Castellví, I. Alfonso, 2017, Chemistry.

Designed folding of pseudopeptides: the transformation of a configurationally driven preorganization into a stereoselective multicomponent macrocyclization reaction.

S. Luis, M. Burguete, I. Alfonso, 2008, Chemistry.

Crystal structures of the HCl salts of pseudopeptidic macrocycles display “knobs into holes” hydrophobic interactions between aliphatic side chains

S. Luis, M. Burguete, I. Alfonso, 2009 .

Polyhydroxylated bicyclic isoureas and guanidines are potent glucocerebrosidase inhibitors and nanomolar enzyme activity enhancers in Gaucher cells.

T. Butters, A. Llebaria, I. Alfonso, 2011, Journal of the American Chemical Society.

Supramolecular protection from the enzymatic tyrosine phosphorylation in a polypeptide.

S. Luis, I. Alfonso, E. Faggi, 2016, Chemical communications.

Pseudopeptidic compounds for the generation of dynamic combinatorial libraries of chemically diverse macrocycles in aqueous media.

I. Alfonso, Jordi Solà, Joan Atcher, 2016, Organic & biomolecular chemistry.

Study of the Chemoselectivity in the Aminolysis Reaction of Methyl Acrylate Catalysed by Lipase B from Candida antarctica

V. Gotor‐Fernández, I. Alfonso, V. Gotor, 2005 .

Asymmetric organic synthesis with enzymes

I. Alfonso, V. Gotor, Eduardo García-Urdiales, 2008 .

Copper(ii) complexes of macrocyclic and open-chain pseudopeptidic ligands: synthesis, characterization and interaction with dicarboxylates.

Laura Rodríguez, I. Alfonso, M. Bolte, 2015, Dalton transactions.

Pseudopeptidic cages as receptors for N-protected dipeptides.

S. Luis, A. Moure, I. Alfonso, 2014, The Journal of organic chemistry.

Molecular recognition of N-protected dipeptides by pseudopeptidic macrocycles: a comparative study of the supramolecular complexes by ESI-MS and NMR.

S. Luis, M. Burguete, I. Alfonso, 2010, Organic & biomolecular chemistry.

15N NMR spectroscopic and theoretical GIAO-DFT studies for the unambiguous characterization of disubstituted 1,2,3-triazoles.

A. Messeguer, I. Alfonso, J. Bujons, 2013, Organic & biomolecular chemistry.

Comprar Asymmetric Organic Synthesis with Enzymes | Vicente Gotor | 9783527318254 | Wiley

I. Alfonso, V. Gotor, Eduardo García-Urdiales, 2008 .

Pseudopeptidic fluorescent on-off pH sensor based on pyrene excimer emission: Imaging of acidic cellular organelles

S. Luis, I. Alfonso, J. Casas, 2016 .

Salt-induced adaptation of a dynamic combinatorial library of pseudopeptidic macrocycles: unraveling the electrostatic effects in mixed aqueous media.

A. Moure, I. Alfonso, Joan Atcher, 2015, Chemistry.

Cationic Peptides and Peptidomimetics Bind Glycosaminoglycans as Potential Sema3A Pathway Inhibitors.

A. Messeguer, A. Moure, I. Alfonso, 2016, Biophysical journal.

Dynamic Covalent Identification of an Efficient Heparin Ligand.

A. Messeguer, I. Alfonso, D. Carbajo, 2018, Angewandte Chemie.

Dynamic Covalent Identification of an Efficient Heparin Ligand

A. Messeguer, I. Alfonso, D. Carbajo, 2018, Angewandte Chemie.

MCR-ALS analysis of 1H NMR spectra by segments to study the zebrafish exposure to acrylamide

R. Tauler, Francesc Puig-Castellví, B. Piña, 2020, Analytical and Bioanalytical Chemistry.

The effect of DMSO in the aqueous thiol–disulphide dynamic covalent chemistry of model pseudopeptides

I. Alfonso, Joan Atcher, 2013 .

From simplicity to complex systems with bioinspired pseudopeptides.

I. Alfonso, 2016, Chemical communications.

Minimalistic amino amides as models to study N–H⋯π interactions and their implication in the side chain folding of pseudopeptidic molecules

S. Luis, I. Alfonso, E. Faggi, 2013 .

Molecular rotors as simple models to study amide NH-aromatic interactions and their role in the folding of peptide-like structures.

S. Luis, M. Burguete, I. Alfonso, 2007, The Journal of organic chemistry.

Compression of multidimensional NMR spectra allows a faster and more accurate analysis of complex samples.

R. Tauler, Francesc Puig-Castellví, B. Piña, 2018, Chemical communications.

Efficient synthesis of pseudopeptidic molecular cages.

S. Luis, A. Moure, I. Alfonso, 2012, Chemistry.

Chiral triazolium salts and ionic liquids: from the molecular design vectors to their physical properties through specific supramolecular interactions.

S. García‐Granda, E. García‐Verdugo, S. Luis, 2013, Chemistry.

Enantiopure Triazolium Salts: Chemoenzymatic Synthesis and Applications in Organocatalysis

S. García‐Granda, E. García‐Verdugo, S. Luis, 2011 .

Biocatalytic and biomimetic aminolysis reactions: useful tools for selective transformations on polyfunctional substrates.

I. Alfonso, V. Gotor, 2004, Chemical Society reviews.

An efficient dynamic asymmetric catalytic system within a zinc-templated network.

I. Alfonso, Jordi Solà, C. Jimeno, 2019, Chemical communications.

A Dynamic Chemical Network for Cystinuria Diagnosis.

I. Alfonso, Jordi Solà, María J. Lafuente, 2018, Angewandte Chemie.

Stereoselective recognition of the Ac-Glu-Tyr-OH dipeptide by pseudopeptidic cages.

S. Luis, I. Alfonso, E. Faggi, 2015, Organic & biomolecular chemistry.

Gemini amphiphilic pseudopeptides: synthesis and preliminary study of their self-assembling properties

S. Luis, M. Burguete, I. Alfonso, 2010 .

Sensing, transport and other potential biomedical applications of pseudopeptides.

S. Luis, I. Alfonso, E. Faggi, 2019, Current medicinal chemistry.

Biological activity of synthetic ionophores: ion transporters as prospective drugs?

R. Quesada, I. Alfonso, 2013 .

Unraveling the molecular recognition of amino acid derivatives by a pseudopeptidic macrocycle: ESI-MS, NMR, fluorescence, and modeling studies.

S. Luis, M. Burguete, I. Alfonso, 2009, The Journal of organic chemistry.

Conformational promiscuity in triazolamers derived from quaternary amino acids mimics peptide behaviour.

I. Alfonso, Jordi Solà, M. Bolte, 2015, Organic & biomolecular chemistry.

Highly diastereoselective amplification from a dynamic combinatorial library of macrocyclic oligoimines.

I. Alfonso, V. Gotor, Almudena González-Álvarez, 2006, Chemical communications.

Optically active macrocyclic hexaazapyridinophanes decorated at the periphery: synthesis and applications in the NMR enantiodiscrimination of carboxylic acids

E. Busto, V. Gotor‐Fernández, I. Alfonso, 2010 .

Efficient syntheses of new chiral peptidomimetic macrocycles through a configurationally driven preorganization

S. Luis, M. Burguete, I. Alfonso, 2005 .

Chemoenzymatic syntheses of new optically active C2-symmetrical macrocyclic polyazacyclophanes

I. Alfonso, V. Gotor, Mercedes Rubio, 2005 .

Structurally disfavoured pseudopeptidic macrocycles through anion templation.

S. Luis, M. Burguete, I. Alfonso, 2011, Chemical communications.

Molecular recognition of zwitterions with artificial receptors.

I. Alfonso, Jordi Solà, 2020, Chemistry, an Asian journal.

Reversible Self-Assembly of Water-Soluble Gold(I) Complexes.

M. Malfois, J. C. Lima, Laura Rodríguez, 2017, Inorganic chemistry.

Novel supramolecular nanostructures constituted by the noncovalent self-organization of small metallophilic molecules

Guez, M. Malfois, J. C. Lima, 2017 .

Biocatalytic approaches toward the synthesis of both enantiomers of trans-cyclopentane-1,2-diamine.

I. Alfonso, V. Gotor, A. Luna, 2002, Organic letters.

Sequential biocatalytic resolution of (±)-trans-cyclohexane-1,2-diamine. Chemoenzymatic synthesis of an optically active polyamine

C. Astorga, I. Alfonso, V. Gotor, 1996 .

Intramolecular hydrogen bonding guides a cationic amphiphilic organocatalyst to highly stereoselective aldol reactions in water

I. Alfonso, Ángel M. Valdivielso, C. Jimeno, 2015 .

Update 1 of: Enantioselective enzymatic desymmetrizations in organic synthesis.

I. Alfonso, Ignacio Alfonso, Eduardo García-Urdiales, 2011, Chemical reviews.

Deciphering the roles of multiple additives in organocatalyzed Michael additions.

X. Companyó, I. Alfonso, C. Jimeno, 2016, Chemical communications.

Microbial transformation of two 15α-hydroxy-ent-kaur-16-ene diterpenes by Mucor plumbeus

Victoria González-Vallejo, I. Alfonso, B. Fraga, 2010 .

Enantioselective enzymatic desymmetrizations in organic synthesis.

I. Alfonso, V. Gotor, Eduardo García-Urdiales, 2005, Chemical reviews.

Regioselective Synthesis of a Family of β‐Lactams Bearing a Triazole Moiety as Potential Apoptosis Inhibitors

A. Messeguer, I. Alfonso, M. Orzáez, 2016, ChemistryOpen.

Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole Moiety.

E. Pérez-Payá, A. Messeguer, I. Alfonso, 2015, Chemistry.

A ferromagnetic [Cu3(OH)2]4+ cluster formed inside a tritopic nonaazapyridinophane: crystal structure and solution studies.

S. García‐Granda, E. Garcı́a-España, F. Lloret, 2009, Angewandte Chemie.

Selective Host Amplification from a Dynamic Combinatorial Library of Oligoimines for the Syntheses of Different Optically Active Polyazamacrocycles

S. García‐Granda, I. Alfonso, V. Gotor, 2004 .

Unprecedented asymmetric induction through configurationally stable lithium N-(α-methylbenzyl)phosphinamides. A new entry to enantiomerically pure γ-aminophosphinic acids and esters

M. Iglesias, I. Alfonso, I. Fernández, 2005 .

Lipase catalysed Michael addition of secondary amines to acrylonitrile.

I. Alfonso, V. Gotor, Oliver Torre, 2004, Chemical communications.

Optimizing the control of apoptosis by amide/triazole isosteric substitution in a constrained peptoid.

E. Pérez-Payá, A. Messeguer, I. Alfonso, 2013, European journal of medicinal chemistry.

Exploiting complexity to implement function in chemical systems.

I. Alfonso, Jordi Solà, C. Jimeno, 2020, Chemical communications.

CHEMOENZYMATIC SYNTHESES OF POLYAMINES AND TETRAAZAMACROCYCLES

C. Astorga, I. Alfonso, V. Gotor, 2002 .

The emergence of halophilic evolutionary patterns from a dynamic combinatorial library of macrocyclic pseudopeptides.

A. Moure, I. Alfonso, Joan Atcher, 2013, Chemical communications.

Desymmetrization of dimethyl 3-substituted glutarates through enzymatic ammonolysis and aminolysis reactions

I. Alfonso, V. Gotor, M. López-García, 2003 .

Conformationally Biased Selective Alkylation of trans-Cyclohexane-1,2-bis(sulfonamide) Assisted by Solvent-Tuned Protecting Groups: Applications to the Synthesis of a Large Optically Active Polyazamacrocycle†

I. Alfonso, V. Gotor, C. Peña, 2006 .

From salts to ionic liquids by systematic structural modifications: a rational approach towards the efficient modular synthesis of enantiopure imidazolium salts.

S. García‐Granda, E. García‐Verdugo, S. Luis, 2010, Chemistry.

Structural studies of two protonated forms of a C2 symmetrical optically active cyclam derivative

S. García‐Granda, C. Astorga, I. Alfonso, 2000 .

Anion-templated syntheses of pseudopeptidic macrocycles.

S. Luis, M. Burguete, I. Alfonso, 2006, Angewandte Chemie.

A Degenerate Metal-Templated Catalytic System with Redundant Functional Groups for the Asymmetric Aldol Reaction

I. Alfonso, Jordi Solà, C. Jimeno, 2022, The Journal of organic chemistry.

Highly efficient biocatalytic resolution of cis- and trans-3-aminoindan-1-ol: syntheses of enantiopure orthogonally protected cis- and trans-indane-1,3-diamine.

I. Alfonso, V. Gotor, M. López-García, 2004, Chemistry.

Chiral Molecular Receptors Based on trans-Cyclohexane-1,2-diamine

I. Alfonso, 2010 .

A simple helical macrocyclic polyazapyridinophane as a stereoselective receptor of biologically important dicarboxylates under physiological conditions.

E. Garcı́a-España, V. Gotor‐Fernández, I. Alfonso, 2008, The Journal of organic chemistry.

A highly enantioselective abiotic receptor for malate dianion in aqueous solution.

E. Garcı́a-España, I. Alfonso, V. Gotor, 2006, Chemical communications.

An azamacrocyclic receptor as efficient polytopic chiral solvating agent for carboxylic acids

I. Alfonso, V. Gotor, Almudena González-Álvarez, 2006 .

Structurally Selective Assembly of a Specific Macrobicycle from a Dynamic Library of Pseudopeptidic Disulfides

I. Alfonso, Jordi Solà, María J. Lafuente, 2019, ChemSystemsChem.

Adaptive Correction from Virtually Complex Dynamic Libraries: The Role of Noncovalent Interactions in Structural Selection and Folding.

I. Alfonso, Jordi Solà, Joan Atcher, 2015, Chemistry.

Constitutional self-selection from dynamic combinatorial libraries in aqueous solution through supramolecular interactions.

I. Alfonso, Jordi Solà, Joan Atcher, 2014, Chemical communications.

Non‐covalent Interactions for the Preparation of Pseudopeptidic Synthetic Compounds and Materials

I. Alfonso, Jordi Solà, 2016 .

Tight and selective caging of chloride ions by a pseudopeptidic host.

S. Luis, M. Burguete, I. Alfonso, 2014, Chemistry.

Tuning chloride binding, encapsulation, and transport by peripheral substitution of pseudopeptidic tripodal small cages.

S. Luis, M. Burguete, R. Quesada, 2012, Chemistry.

Supramolecular control for the modular synthesis of pseudopeptidic macrocycles through an anion-templated reaction.

S. Luis, M. Burguete, I. Alfonso, 2008, Journal of the American Chemical Society.

Anion Recognition and Induced Self-Assembly of an α,γ-Cyclic Peptide To Form Spherical Clusters.

J. Granja, M. Amorín, I. Alfonso, 2016, Angewandte Chemie.

Receptors for Zwitterionic Species

S. Luis, I. Alfonso, F. Galindo, 2012 .

Live-Cell-Templated Dynamic Combinatorial Chemistry.

I. Alfonso, D. Carbajo, J. Bujons, 2020, Angewandte Chemie.

Entropy-driven homochiral self-sorting of a dynamic library.

I. Alfonso, Joan Atcher, J. Bujons, 2017, Chemical communications.

Spontaneous macrocyclization through multiple dynamic cyclic aminal formation.

E. Pérez-Inestrosa, I. Alfonso, D. Carbajo, 2021, Chemical communications.

Bioinspired chemistry based on minimalistic pseudopeptides.

S. Luis, I. Alfonso, 2014, Accounts of chemical research.

Stimulus responsive self-assembly of Gemini Amphiphilic Pseudopeptides

S. Luis, M. Burguete, I. Alfonso, 2011 .

Crystal Structure of the N-Benzyloxycarbonyl-alanyl-phenylalanyl-methyl Ester: The Importance of the H-Bonding Pattern

S. Luis, M. Burguete, I. Alfonso, 2011 .

Structural diversity in the self-assembly of pseudopeptidic macrocycles.

E. García‐Verdugo, S. Luis, M. Burguete, 2010, Chemistry.

Chiral imidazolium receptors for citrate and malate: the importance of the preorganization.

E. García‐Verdugo, S. Luis, Raúl Porcar, 2014, The Journal of organic chemistry.

pH-dependent chloride transport by pseudopeptidic cages for the selective killing of cancer cells in acidic microenvironments.

R. Quesada, I. Alfonso, J. Casas, 2019, Angewandte Chemie.

Dynamic Combinatorial Optimization of In Vitro and In Vivo Heparin Antidotes

M. Guerra-Rebollo, E. Prats, I. Alfonso, 2022, Journal of medicinal chemistry.

Interplay between hydrophilic and hydrophobic interactions in the self-assembly of a gemini amphiphilic pseudopeptide: from nano-spheres to hydrogels.

S. Luis, M. Burguete, I. Alfonso, 2012, Chemical communications.

Silver complexes of peptidomimetic polyazapyridinophanes. The influence of the bonding cavity size and the nature of side chains.

S. Luis, J. Miravet, I. Alfonso, 2006, Organic & biomolecular chemistry.

A hydrogen-bonding-modulated molecular rotor: environmental effect in the conformational stability of peptidomimetic macrocyclic cyclophanes.

S. Luis, M. Burguete, I. Alfonso, 2006, The Journal of organic chemistry.

Cycloalkane-1,2-diamine derivatives as chiral solvating agents. Study of the structural variables controlling the NMR enantiodiscrimination of chiral carboxylic acids

I. Alfonso, V. Gotor, Javier González‐Sabín, 2008 .

New pincer-like receptor derived from trans-cyclopentane-1,2-diamine as a chiral shift reagent for carboxylic acids

I. Alfonso, V. Gotor, Javier González‐Sabín, 2007 .

Simple and straightforward synthesis of novel enantiopure ionic liquids via efficient enzymatic resolution of (±)-2-(1H-imidazol-1-yl)cyclohexanol

S. García‐Granda, E. García‐Verdugo, S. Luis, 2007 .

Optically Active Hexaazamacrocycles: Protonation Behavior and Chiral‐Anion Recognition

J. Lehn, I. Alfonso, V. Gotor, 2001 .

Chemoenzymatic syntheses of two optically active hexa-azamacrocycles

I. Alfonso, V. Gotor, F. Rebolledo, 1999 .

Electrospray Ionization Mass Spectrometry (ESI-MS) as a Useful Tool for Fast Evaluation of Anion and Cation Complexation Abilities of a Cyclam Derivative

C. Astorga, I. Alfonso, V. Gotor, 2005 .

Solvent dependent selective alkylation of a bis(sulfonamide) for the synthesis of a DNA-binding chiral polyamine

N. Voelcker, I. Alfonso, V. Gotor, 2005 .

Metal-driven assembly of peptidic foldamers: formation of molecular tapes

I. Alfonso, Jordi Solà, M. Bolte, 2016 .

pH‐Dependent Chloride Transport by Pseudopeptidic Cages for the Selective Killing of Cancer Cells in Acidic Microenvironments

R. Quesada, I. Alfonso, J. Casas, 2019, Angewandte Chemie.

Synthesis of second-generation self-assembling Gemini Amphiphilic Pseudopeptides.

S. Luis, I. Alfonso, M. Isabel Burguete, 2019, Journal of colloid and interface science.

Biological activity of synthetic ionophores: ion transporters as prospective drugs?

R. Quesada, I. Alfonso, 2013 .

Molecular cages for biological applications.

I. Alfonso, Jordi Solà, Lucía Tapia, 2021, Organic & biomolecular chemistry.

Conformational analysis of a model synthetic prodiginine.

D. Quiñonero, R. Quesada, M. García-Valverde, 2012, The Journal of organic chemistry.

Synthesis and stereoselective DNA binding abilities of new optically active open-chain polyamines.

N. Voelcker, I. Alfonso, V. Gotor, 2007, The Journal of organic chemistry.

Chiral Molecular Receptors Based on Trans-Cyclohexane-1,2- Diamine

I. Alfonso, 2010 .

Catalyzed Oxidative Corrosion of Porous Silicon Used as an Optical Transducer for Ligand–Receptor Interactions

N. Voelcker, M. Ghadiri, I. Alfonso, 2008, Chembiochem : a European journal of chemical biology.

Desymmetrization of Dimethyl 3‐Substituted Glutarates Through Enzymatic Ammonolysis and Aminolysis Reactions.

I. Alfonso, V. Gotor, M. López-García, 2003 .

OPTICALLY ACTIVE TETRAAZAMACROCYCLES ANALOGOUS TO CYCLAM

C. Astorga, I. Alfonso, V. Gotor, 1999 .

Chemoenzymatic Approach to a (R)-3, 4-Diaminobutanoic Acid Derivative with a Suitable Orthogonal Protection for Solid Phase Peptide Synthesis

I. Alfonso, V. Gotor, M. López-García, 2004 .

A copper-templated, bifunctional organocatalyst: a strongly cooperative dynamic system for the aldol reaction.

I. Alfonso, Jordi Solà, C. Jimeno, 2017, Organic & biomolecular chemistry.

Dynamic assembly of a zinc-templated bifunctional organocatalyst in the presence of water for the asymmetric aldol reaction.

I. Alfonso, Jordi Solà, C. Jimeno, 2015, Chemical communications.

Targeting redox metabolism: the perfect storm induced by acrylamide poisoning in the brain

T. Ziv, A. Admon, M. Faria, 2020, Scientific Reports.

Detection, synthesis and characterization of metabolites of steroid hormones conjugated with cysteine

Ó. Pozo, A. Fabregat, R. Ventura, 2013, Steroids.

Deciphering the Underlying Metabolomic and Lipidomic Patterns Linked to Thermal Acclimation in Saccharomyces cerevisiae.

Romà Tauler, Carmen Bedia, Benjamin Piña, 2018, Journal of proteome research.

A quantitative 1H NMR approach for evaluating the metabolic response of Saccharomyces cerevisiae to mild heat stress

R. Tauler, B. Piña, I. Alfonso, 2015, Metabolomics.

1H NMR metabolomic study of auxotrophic starvation in yeast using Multivariate Curve Resolution-Alternating Least Squares for Pathway Analysis

Romà Tauler, Benjamin Piña, Francesc Puig-Castellví, 2016, Scientific Reports.

Semaphorin 3A—Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

A. Messeguer, A. Moure, I. Alfonso, 2021, Pharmaceuticals.

AuNP–Polymeric Ionic Liquid Composite Multicatalytic Nanoreactors for One-Pot Cascade Reactions

E. García‐Verdugo, S. Luis, S. Montolio, 2016 .

Live‐Cell‐Templated Dynamic Combinatorial Chemistry

I. Alfonso, D. Carbajo, J. Bujons, 2020, Angewandte Chemie.

Chemical modulation of peptoids: synthesis and conformational studies on partially constrained derivatives.

E. Pérez-Payá, A. Messeguer, G. Sanclimens, 2011, Chemistry.

Lipase Catalyzed Michael Addition of Secondary Amines to Acrylonitrile.

I. Alfonso, V. Gotor, Oliver Torre, 2004 .

Comparative analysis of 1H NMR and 1H-13C HSQC NMR metabolomics to understand the effects of medium composition in yeast growth.

R. Tauler, B. Piña, I. Alfonso, 2018, Analytical chemistry.

Inhibition of Sema-3A Promotes Cell Migration, Axonal Growth, and Retinal Ganglion Cell Survival

A. Barzilai, A. Messeguer, M. Safrin, 2021, Translational vision science & technology.

Highly stable oil-in-water emulsions with a gemini amphiphilic pseudopeptide

S. Luis, M. Burguete, I. Alfonso, 2015 .

An introduction to one- and two-dimensional lineshape analysis of chemically exchanging systems

C. Waudby, I. Alfonso, 2023, Journal of Magnetic Resonance Open.

Recent Developments in Chiral Polynitrogenated Synthetic Receptors for Anions

I. Alfonso, 2008 .

Dynamic Stereoselection of Peptide Helicates and Their Selective Labeling of DNA Replication Foci in Cells.

Jean‐Didier Maréchal, M. Vázquez, G. Sciortino, 2020, Angewandte Chemie.

Synthesis and characterization of 6β-hydroxyandrosterone and 6β-hydroxyetiocholanolone conjugated with glucuronic acid.

Ó. Pozo, A. Fabregat, R. Ventura, 2015, Drug Testing and Analysis.