C. Metcalfe

发表

Expression of immunoreactive glutathione S-transferases in hepatic neoplasms induced by aflatoxin B1 or 1,2-dimethylbenzanthracene in rainbow trout (Oncorhynchus mykiss).

H. Ferguson, T. Koçal, M. A. Hayes, 1990, Carcinogenesis.

The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies

M. Wadhwa, R. Thorpe, J. Derrick, 2019, The Journal of Biological Chemistry.

Extended terpyridyl and triazine complexes of d6-metal centres

Jim A. Thomas, H. Adams, C. Metcalfe, 2002 .

Immunoregulation through membrane proteins modified by reducing conditions induced by immune reactions

A. Barclay, C. Metcalfe, M. Stegmann, 2013, European journal of immunology.

The first World Health Organization International Standard for infliximab products: A step towards maintaining harmonized biological activity

M. Wadhwa, C. Bird, P. Rigsby, 2018, mAbs.

Labile disulfide bonds are common at the leucocyte cell surface

P. Cresswell, A. Barclay, L. Ciaccia, 2011, Open Biology.

Structures of CD6 and Its Ligand CD166 Give Insight into Their Interaction

C. Robinson, Steven Johnson, S. Lea, 2015, Structure.

Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase

P. Moody, M. Blakeley, A. Ostermann, 2014, Science.

Tuning the formation of a covalent haem-protein link by selection of reductive or oxidative conditions as exemplified by ascorbate peroxidase.

S. Ferguson, C. Metcalfe, E. Raven, 2007, The Biochemical journal.

Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

S. Mundell, C. Metcalfe, G. Pula, 2016, PloS one.

Commonly setting biological standards in rare diseases

Javier Martin, G. Mattiuzzo, N. Rose, 2019, Expert Opinion on Orphan Drugs.

Reduction of leucocyte cell surface disulfide bonds during immune activation is dynamic as revealed by a quantitative proteomics workflow (SH-IQ)

A. Barclay, C. Metcalfe, M. Stegmann, 2018, Open Biology.

Proton delivery to ferryl heme in a heme peroxidase: enzymatic use of the Grotthuss mechanism.

I. Efimov, P. Moody, C. Metcalfe, 2011, Journal of the American Chemical Society.

Autocatalytic formation of green heme: evidence for H2O2-dependent formation of a covalent methionine-heme linkage in ascorbate peroxidase.

Kuldip Singh, C. Metcalfe, S. Mistry, 2004, Journal of the American Chemical Society.

Homodimerization of the Lymph Vessel Endothelial Receptor LYVE-1 through a Redox-labile Disulfide Is Critical for Hyaluronan Binding in Lymphatic Endothelium

D. Jackson, A. Yamauchi, Omer Dushek, 2016, The Journal of Biological Chemistry.

Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor

P. Cresswell, A. Barclay, C. Metcalfe, 2012, Open Biology.

Fine Specificity and Molecular Competition in SLAM Family Receptor Signalling

Marion H. Brown, T. Wilson, C. Metcalfe, 2014, PloS one.

A Review of Methodologies for the Detection, Quantitation, and Localization of Free Cysteine in Recombinant Proteins: A Focus on Therapeutic Monoclonal Antibodies

C. Metcalfe, 2022, Frontiers in Molecular Biosciences.

CD44 Binding to Hyaluronic Acid Is Redox Regulated by a Labile Disulfide Bond in the Hyaluronic Acid Binding Site

A. Barclay, C. Metcalfe, M. Stegmann, 2015, PloS one.

Kinetically inert transition metal complexes that reversibly bind to DNA.

Jim A. Thomas, C. Metcalfe, 2003, Chemical Society reviews.

Studies on the interaction of extended terpyridyl and triazine metal complexes with DNA.

Jim A. Thomas, C. Metcalfe, Chatna Rajput, 2006, Journal of inorganic biochemistry.

A proximity-based in silico approach to identify redox-labile disulfide bonds: The example of FVIII

R. Pisano, A. Riches, C. Metcalfe, 2022, PloS one.

A facile synthetic route to bimetallic ReI complexes containing two dppz DNA intercalating ligands.

Jim A. Thomas, C. Metcalfe, M. Webb, 2002, Chemical communications.

An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective.

P. Moody, C. Metcalfe, E. Raven, 2010, Archives of biochemistry and biophysics.

A facile route to bimetallic ruthenium dipyridophenazine complexes.

Jim A. Thomas, C. Metcalfe, I. Haq, 2004, Inorganic chemistry.

A ruthenium dipyridophenazine complex that binds preferentially to GC sequences.

Jim A. Thomas, H. Adams, C. Metcalfe, 2003, Chemical communications.

Maintaining ‘standards’ for biosimilar monoclonal antibodies

M. Wadhwa, S. Hufton, C. Schneider, 2021, Nature Biotechnology.

Nature of the Ferryl Heme in Compounds I and II*

P. Moody, C. Metcalfe, E. Raven, 2010, The Journal of Biological Chemistry.

Evidence for heme oxygenase activity in a heme peroxidase.

P. Moody, C. Metcalfe, Zoi Pipirou, 2009, Biochemistry.

Electrochemical and photophysical properties of DNA metallo-intercalators containing the ruthenium(II) tris(1-pyrazolyl)methane unit.

Jim A. Thomas, H. Adams, S. Foxon, 2007, Inorganic Chemistry.

Deprotonation of a ruthenium (II) complex incorporating a bipyrazole ligand leading to optical and electrochemical switching

Jim A. Thomas, H. Adams, C. Metcalfe, 2001 .

Peroxide-dependent formation of a covalent link between Trp51 and the heme in cytochrome c peroxidase.

V. Guallar, A. Bottrill, C. Metcalfe, 2009, Biochemistry.

OX133, a monoclonal antibody recognizing protein-bound N-ethylmaleimide for the identification of reduced disulfide bonds in proteins

A. Barclay, I. Jones, E. Fenouillet, 2016, mAbs.

Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase.

P. Moody, C. Metcalfe, J. Basran, 2008, Biochemistry.

Crystal structure of guaiacol and phenol bound to a heme peroxidase

Emma L Raven, Emma J Murphy, Clive L Metcalfe, 2012, The FEBS journal.

The Tuberculosis Prodrug Isoniazid Bound to Activating Peroxidases*

K. Brown, P. Moody, C. Metcalfe, 2008, Journal of Biological Chemistry.

Kinetically Inert Transition Metal Complexes that Reversibly Bind to DNA

Jim A. Thomas, C. Metcalfe, Clive Metcalfe, 2003 .

Observation of broken time-reversal symmetry in the heavy-fermion superconductor UPt3

M. Blakeley, W. Halperin, A. Ostermann, 2014, Science.

Nature of the Ferryl Heme in Compounds I and II*

P. Moody, C. Metcalfe, E. Raven, 2010, The Journal of Biological Chemistry.

Evaluation of Tryptic Peptides from Neisseria meningitidis Outer Membrane Proteins PorA and PorBDigestion, Peptides

C. Metcalfe, J. Wheeler, A. Bristow, 2017 .