Naomi L Kruhlak

发表

Assessing the Structural and Pharmacological Similarity of Newly Identified Drugs of Abuse to Controlled Substances Using Public Health Assessment via Structural Evaluation

Christopher R Ellis, Rebecca Racz, Naomi L Kruhlak, 2019, Clinical pharmacology and therapeutics.

A structural feature-based computational approach for toxicology predictions

Naomi L Kruhlak, Chihae Yang, Luis G Valerio, 2010, Expert opinion on drug metabolism & toxicology.

Transitioning to composite bacterial mutagenicity models in ICH M7 (Q)SAR analyses.

Naomi L Kruhlak, Lidiya Stavitskaya, Curran Landry, 2019, Regulatory toxicology and pharmacology : RTP.

Construction and Consensus Performance of (Q)SAR Models for Predicting Phospholipidosis Using a Dataset of 743 Compounds

Naomi L Kruhlak, Amabel M Orogo, Sydney S Choi, 2012, Molecular informatics.

In silico toxicology protocols.

Tudor I. Oprea, Naomi L Kruhlak, Lidiya Stavitskaya, 2018, Regulatory toxicology and pharmacology : RTP.

Combined Use of MC4PC, MDL-QSAR, BioEpisteme, Leadscope PDM, and Derek for Windows Software to Achieve High-Performance, High-Confidence, Mode of Action–Based Predictions of Chemical Carcinogenesis in Rodents

Naomi L Kruhlak, R Daniel Benz, Chihae Yang, 2008, Toxicology mechanisms and methods.

Construction and analysis of a human hepatotoxicity database suitable for QSAR modeling using post-market safety data.

Naomi L Kruhlak, Xiao Zhu, N. Kruhlak, 2014, Toxicology.

Genetic toxicology in silico protocol.

Raymond R Tice, Naomi L Kruhlak, Lidiya Stavitskaya, 2019, Regulatory toxicology and pharmacology : RTP.

Testing computational toxicology models with phytochemicals.

Naomi L Kruhlak, R Daniel Benz, Luis G Valerio, 2010, Molecular nutrition & food research.

Progress in QSAR toxicity screening of pharmaceutical impurities and other FDA regulated products.

Naomi L Kruhlak, R Daniel Benz, Edwin J Matthews, 2007, Advanced drug delivery reviews.

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: is aromatic N-oxide a structural alert for predicting DNA-reactive mutagenicity?*

Naomi L Kruhlak, Lidiya Stavitskaya, Alexander Amberg, 2018, Mutagenesis.

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans. Part A: use of FDA post-market reports to create a database of hepatobiliary and urinary tract toxicities.

Naomi L Kruhlak, R Daniel Benz, Edwin J Matthews, 2009, Regulatory toxicology and pharmacology : RTP.

A comprehensive model for reproductive and developmental toxicity hazard identification: I. Development of a weight of evidence QSAR database.

Naomi L Kruhlak, Edwin J Matthews, Joseph F Contrera, 2007, Regulatory toxicology and pharmacology : RTP.

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part B. Use of (Q)SAR systems for early detection of drug-induced hepatobiliary and urinary tract toxicities.

Naomi L Kruhlak, R Daniel Benz, Gilles Klopman, 2009, Regulatory toxicology and pharmacology : RTP.

A comprehensive model for reproductive and developmental toxicity hazard identification: II. Construction of QSAR models to predict activities of untested chemicals.

Naomi L Kruhlak, Gilles Klopman, Edwin J Matthews, 2007, Regulatory toxicology and pharmacology : RTP.

Comparison of MC4PC and MDL-QSAR rodent carcinogenicity predictions and the enhancement of predictive performance by combining QSAR models.

Naomi L Kruhlak, R Daniel Benz, Edwin J Matthews, 2007, Regulatory toxicology and pharmacology : RTP.

Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.

Naomi L Kruhlak, R Daniel Benz, Edwin J Matthews, 2004, Current drug discovery technologies.

Identification of structure-activity relationships for adverse effects of pharmaceuticals in humans: Part C: use of QSAR and an expert system for the estimation of the mechanism of action of drug-induced hepatobiliary and urinary tract toxicities.

Naomi L Kruhlak, R Daniel Benz, Edwin J Matthews, 2009, Regulatory toxicology and pharmacology : RTP.

Development of a Phospholipidosis Database and Predictive Quantitative Structure-Activity Relationship (QSAR) Models

Naomi L Kruhlak, Sydney S Choi, Joseph F Contrera, 2008, Toxicology mechanisms and methods.